Urinary Track Infection

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    Paired kidney

    UretersUrinary bladder

    Urethra

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    Cystitis and urethritis, the two

    forms of lower urinary track

    infection (UTI), are nearly ten

    times more common in femalesthan in males. Lower UTI is also

    a prevalent bacterial disease in

    children, with girls also most

    commonly affected.

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    In men and in children of either sex,

    lower UTIs are usually related toanatomic or physiologic

    abnormalities and therefore require

    extremely close evaluation. UTIstypically respond readily to

    treatment, but recurrence and

    resistant bacterial flare-up during

    therapy are possible..

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    Ascending infection by a singlegram negative enteric

    bacterium ( ESCHERIA COLI,KLEBSIELLA,PROTEUS,ENTERO

    BACTER,PSEUDONOMAS, OR

    SERRATIA)

    Simultaneous infection with

    multiple pathogens.

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    Benign prostatic hyperplasiaBowel incontinence

    CatheterizationCystoscopy

    DiabetesHistory of analgesic or reflux

    nephropathy

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    Immobility or decreased

    mobility Incomplete emptying of the

    bladder (in elderly patients)

    Indwelling urinary catheter

    Lack of adequate fluids

    Pregnancy

    Prostatitis

    Urethral strictures

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    Abdominal pain or tenderness overthe bladder area.

    Chills

    Cramps or bladder spasm Dysuria Feeling o f warmth during

    urination Fever, flank pain

    Hematuria

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    Itching

    Low back painMalaise

    Nausea, vomitting

    Nocturia

    Urethral discharge in males

    Urinary frequency and

    urgency

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    Characteristic signs and symptoms andmicroscopic urinalysis showing redblood cell and white blood cell counts

    greater than 10 high power fieldsuggest lower UTI. A clean catch, midstream urine

    specimen revealing a bacterial count ofmore than 100,000/ml confirms thediagnosis. Lower counts don't necessarilyrule out infection,

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    Especially if the patient is voiding

    frequently, because bacteria require

    30 to 45 minutes to reproduce in

    urine. Careful midstream, clean

    catch collection is preferred tocatheterization, which can reinfect

    the bladder with urethral bacteria.

    Sensitivity testing determines theappropriate therapeutic

    antimicrobial agent.

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    Sensitivity testing determines the

    appropriate therapeutic

    antimicrobial agent.

    Voiding cystoureterography or

    excretory urography maydisclose congenital anomalies

    that predispose the patient torecurrent UTIs.

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    Appropriate antimicrobials are thetreatment of choice for most initial

    lower UTIs. a 7 to 10 day course of

    antibiotic therapy is standard, but

    recent studies suggest that a single

    dose of an antibiotic or a 3 to 5 dayantibiotic regimen may be sufficient

    to render the urine sterile.

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    After 3 days of urine antibiotic

    therapy, urine culture should

    show no organisms.

    If the urine isnt sterile after 3

    days of antibiotic therapy,

    bacterial resistance has probably

    occurred, making the use ofdifferent antimicrobial necessary.

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    Single dose antibiotic therapy

    with amoxicillin or cotrimoxazole

    may be effective in females with

    an acute, uncomplicated UTI. A

    urine culture taken 1 to 2 weekslater indicates whether the

    infection has been eradicated

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    Teach the female patient how toclean the perineum properly and

    keep the labia separated during

    voiding to collect a clean-catch,

    midstream urine specimen. Explain

    that an uncontaminated midstreamspecimen is essential for accurate

    diagnosis.

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    Watch for GI disturbances from

    antimicrobial therapy.Teach the patient how to

    prevent and treat UTIs.

    Collect all urine samples for

    culture sensitivity testing

    carefully and promptly..

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    Paracetamol

    AmpicillinGentamicin sulfate

    Bacillus clausil