UPenn Prevention Research Center’s CPCRN

Collaborating Center

University of Pennsylvania (UPenn) Prevention Research Center is a new PRC, 2014-2019

Principal Investigator: Karen Glanz, PhD, MPH

This presentation was supported by Cooperative Agreement Number U48 DP005053 from the Centers for Disease Control and Prevention. The findings and conclusions in this presentation are those of the author(s) and do not necessarily represent the official position of the Centers for Disease Control and Prevention.

BackgroundPurpose of the CPCRN:to work with partners to accelerate the implementation of evidence-based cancer prevention and control in communities

Context of our CPCRN Collaborating Center:• UPenn PRC focus: community-based chronic disease

prevention and reducing health disparities in Southeastern Pennsylvania

• Deeply involved with the Abramson Cancer Center (ACC) at the University of Pennsylvania

• We have worked on & are involved with relevant community organizations including state and local health departments and federally qualified health centers.

Specific Aims1. Establish and maintain the infrastructure within the UPenn PRC to lead and manage a program of community-based intervention research in cancer prevention and control.

2. Form and expand partnerships to advance community-based intervention research in cancer prevention and control in Southeastern Pennsylvania (SEPa) and the surrounding region.

3. Expand community-based dissemination and implementation research on cancer prevention and control in SEPa and the region, including the state of Pennsylvania, through the use of:a) Evidence Academies and b) A Community-Engaged Scholars program of collaborative pilot

grant funding.

Planned Research Aim

Address critical gaps in the uptake of evidence-based strategies to increase colorectal cancer screening - by conducting implementation

research to increase systematic and opportunistic screening for colorectal cancer in primary care settings

- especially for disadvantaged and minority adults

Our TeamKaren Glanz, PhD, MPH (PI)

• PI of the Emory University PRC and CPCRN Network Center from 2004 to 2009

• Director, Community Engagement & Research Core, UPenn CTSA• Director, Recruitment – Outcomes Core (ROAR), Abramson Cancer

Center• Co-Chair, Implementation Sciences Working Group, 2012-2013• Member, Community Guide Task Force

Chyke A. Doubeni, MD, FRCS, MPH• Presidential Associate Professor of Family Medicine and

Community Health, and Associate Professor of Epidemiology• (Multiple) PI, PROSPR Network (CRC screening improvement)• HMO Research Network• CRC Screening, quality of screening, health disparities

Our Team (cont’d)David T. Grande, MD, MPA•Internist, health policy researcher•Making improvements to the health care safety net in Philadelphia•FQHC’s, emerging healthcare delivery/technology, reimbursement, access to care

Carmen E. Guerra, MD, MSCE•Associate Director of Diversity and Outreach, ACC•Cancer screening research, vulnerable populations, navigators•Active in regional & state cancer organizations and public health

John R. Kimberly, PhD (Wharton School)• Organizational behavior, health care management, implementation

science• Chair, Implementation Sciences Working Group, 2011-2013

Cathy Melvin, PhD, MPH • Consultant (MUSC)

Ideas/ProjectsAccess to care and cancer screening in FQHC's under the Affordable Care Act

• Multiple costs and influx of new patients• Lines between free screenings and deductibles • Affect on screening utilization and use of evidence-based

interventions to promote screening• Collaboration to study and identify ways to improve screening in

lower-income populations

Why a Network Project? • Healthcare markets are heterogeneous, states have varied policies,

and hard to do a strong study in a single institution or geographic area

• Results would be more impactful with cross-center network collaboration

Ideas: Cross-Center ProjectsCervical cancer screening:  Implementation of new guidelines

• New Cervical Cancer screening guidelines were released by the USPSTF and other professional groups in 2012

• Potential for de-escalation of intensity and frequency of screening, do-it-yourself home testing, HPV testing combined with Pap tests, and changing clinical practices

• Study of the implementation of new guidelines could be timely and important

Why a Network Project? • CPCRN collaborating centers have relationships with different types

of healthcare institutions and clinics  • A multi-center study on this topic would be stronger than one

conducted in a single institution or geographic area • Results of a "starter" cross-center network collaboration on this topic

could rapidly lead to a larger implementation science study

Questions, Comments