Understanding Smoking Etiology through TVE Models Society for Research on Nicotine and Tobacco March...
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Transcript of Understanding Smoking Etiology through TVE Models Society for Research on Nicotine and Tobacco March...
Understanding Smoking Etiology through TVE Models
Society for Research on Nicotine and Tobacco
March 13, 2012
Understanding is influenced by the view…
Nicotine Dependence Symptoms
… and by the timing of that view
Direction of relationship between smoking and ND?
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7 20 38 75 150
Pro
ba
bil
ity
of
De
pe
nd
en
ce
Number of Cigarettes/ Wk
predicted
observed
Dierker et al., 2007, UpTERN data
Relationship between Smoking Quantity and DSM-IV Nicotine Dependence
Methods
Sample: Social-Emotional Contexts of Adolescent Smoking Patterns (SECASP) Study, a longitudinal study of novice adolescent smokers with 6 assessment waves (baseline and 6, 15, 24, and 48 months following baseline).
• Former experimenters (<100 cigarettes/life; no smoking 90 days) • Recent experimenters (<100 cigarettes/life, smoked in 90 days)• Current smokers (>100 cigarettes/life,smoked in past 30 days)
Measures:
Smoking regularity: # days smoked/ past 30.
Smoking/Tobacco exposure: # cigarettes/past 7 days.
Nicotine dependence: Average score on the 10-item adolescent version of the NDSS
Smoking Quantity
Nicotine Dependence
Implications ….
• Intervening on smoking behavior following early exposures with programs that focus on limiting exposure and helping kids to recognize symptoms.
• Low level smokers who have established somewhat more regular patterns will require intervention that addresses symptoms of dependence.
TVE providing an important additional perspective…
Acknowledgements
Arielle Selya, Jennifer Rose, Robin Mermelstein, Don Hedecker, Runze Li and Xianming Tan
Center Grant (NIDA DA010075) awarded to the Methodology Center, Penn State University
P01CA098262 from the National Cancer Institute
R01 DA022313-01A2, R01 DA022313-02S1 and R21DA024260 from the National Institute on Drug Abuse