ENCAPSULATIONENCAPSULATIONNeutral Pellets and Coating Polymers

S ug a r P e l l e t s

Grade

Sugar Pellets SS

Sugar Pellets SS

Sugar Pellets SS

Sugar Pellets SS

Sugar Pellets SS

Sugar Pellets SS

Sugar Pellets SS

Sugar Pellets SS

Sugar Pellets SS

Sugar Pellets SS

Sugar Pellets SS

Sugar Pellets SS

Sugar Pellets SS

Sugar Pellets SS

Sugar Pellets SS

Sugar Pellets SS

Sugar Pellets SS

Sugar Pellets SS

Sugar Pellets SS

Sugar Pellets SS

Sugar Pellets SS

Sugar Pellets SS

Sugar Pellets SS

Sugar Pellets SS

Sugar Pellets SS

Sr. No.

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

20

21

22

23

24

25

Mesh Size (ASTM)

120 – 140

100 – 120

80 – 100

70 – 80

60 – 70

50 – 60

45 – 50

45 – 60

40 – 60

40 – 50

40 – 45

35 – 55

35 – 50

35 – 45

35 – 40

30 – 35

25 – 30

20 – 25

18 – 20

16 – 20

16 – 18

14 – 16

12 – 16

12 – 14

10 – 12

Diameter In mm (µm)

0,106 – 0,125

0,125 – 0,150

0,150 – 0,180

0,180 – 0,212

0,212 – 0,250

0,250 – 0,300

0,300 – 0,355

0,250 – 0,355

0,250 – 0,425

0,300 – 0,425

0,355 – 0,425

0,355 – 0,500

0,300 – 0,500

0,400 – 0,450

0,425 – 0,500

0,500 – 0,600

0,600 – 0,710

0,710 – 0,850

0,850 – 1,000

0,850 – 1,180

1,000 – 1,180

1,180 – 1,400

1,400 – 1,700

1,400 – 1,700

1,700 – 2,000

We do customized special cores / pellets for customers on their annual product requirements.

Disclaimer : This information and our technical advice - whether verbal, in writing or by way of trials - are given in good faith but without warranty, and this also applies where proprietary rights of third parties are involved. Our advice does not release you from the obligation to verify the information currently provided - especially that contained in our safety data and technical information sheets - and to test our products as to their suitability for the intended processes and uses. The application, use and processing our products and the products manufactured by you on the basis of our technical advice are beyond our control and, therefore, entirely your own responsibility.

Sugar Pellets Definitions:

l SPRAYSPHERES™ - SS contains not more than 92 percent of sucrose. Calculated on the dried basis. The dried basis. The remainder consists of

corn starch as per the European Pharmacopoeia.

l Compliance with Ph. Eur., USP/ NF and JP.

l Produced in accordance with the cGMP.

Sugar pellets particle size specifications:

Particle size distribution (analyzed by laser diffraction) shows the symmetrical character of the distribution. The single model profile, associated a

very homogeneous population of SPRAYSPHERES™ - SS.

Sugar Pellets Application:

Used as cores to be coated in the manufacture of dry pharmaceutical / Nutraceutical / herbal / homeopathy form especially for controlled release &

specially formulations.

SPRAYSPHERES™ - Speciality Products (SS):

Definition:

SPRAYSPHERES™ - SS base of sugar & starch pellets coated with cationic polymers.

Application:

l Suitable for very low / high dosage forms and for drugs with a low therapeutic margin.

l Used as cores to be coated in the manufacture of highly hygroscopic / soluble drugs / unstable drug.

l Using SPRAYSPHERES™ - SS can be converted to ready to fill pellet technology.

l Starter cores for Delayed release / Sustained release / time release / pulse release / Controlled release & Immediate release applications, etc.

Application

Used as drug - free cores / starter cores for controlled or sustained release,

immediate release, delayed release applications.

S t a rc h P e l l e t s

Grade

Starch Pellets STS

Starch Pellets STS

Starch Pellets STS

Starch Pellets STS

Starch Pellets STS

Starch Pellets STS

Starch Pellets STS

Starch Pellets STS

Starch Pellets STS

Starch Pellets STS

Sr. No.

1

2

3

4

5

6

7

8

9

10

Mesh Size (ASTM)

12 - 14

16 - 18

18 - 20

20 - 30

30 - 40

40 - 50

50 - 60

60 - 80

80 - 100

100 - 200

We do customized special cores / pellets for customers on their annual product requirements.

Starch Pellets Definitions:

l

The dried basis. The remainder consists of sugar.

l Produced in accordance with the cGMP.

Application:

l Suitable for very low / high dosage forms and for drugs with a low therapeutic margin.

l Used as cores to be coated in the manufacture of highly hygroscopic / soluble drugs /

unstable drug.

l Using SPRAYSPHERES™ - STS can be converted to ready to fill pellet technology.

l Starter cores for Delayed release / Sustained release / time release / pulse release /

Controlled release & Immediate release applications, etc.

Starch spheres contain more than 92 percent of starch. Calculated on the dried basis.

Used as spherical seed cores for drug layering & film coating.

Also used in manufacture of granules / beadlets with sustained /

controlled release, taste masking & other special properties.

Diameter In mm (µm)

1,400 – 1,700

1,000 – 1,180

0,850 – 1,000

–

–

0,300 – 0,425

0,250 – 0,300

–

0,150 – 0,180

–

Application

La c t o s e P e l l e t s

We do customized special cores / pellets for customers on their annual product requirements.

Lactose Pellets Definitions:

l

basis. The dried basis. The remainder consists of Starch.

l Produced in accordance with the cGMP.

l Completely for water soluble application a substitute for sugar.

Application:

l Suitable for very low / high dosage forms and for drugs with a low therapeutic margin.

l Used as cores to be coated in the manufacture of highly hygroscopic / soluble drugs /

unstable drug.

l Using SPRAYSPHERES™ - LS can be converted to ready to fill pellet technology.

l Starter cores for Delayed release / Sustained release / time release / pulse release /

Controlled release & Immediate release applications, etc.

Lactose spheres contain more than 80 percent of lactose. Calculated on the dried

Disclaimer : This information and our technical advice - whether verbal, in writing or by way of trials - are given in good faith but without warranty, and this also applies where proprietary rights of third parties are involved. Our advice does not release you from the obligation to verify the information currently provided - especially that contained in our safety data and technical information sheets - and to test our products as to their suitability for the intended processes and uses. The application, use and processing our products and the products manufactured by you on the basis of our technical advice are beyond our control and, therefore, entirely your own responsibility.

Grade

Lactose Pellets LS

Lactose Pellets LS

Lactose Pellets LS

Lactose Pellets LS

Lactose Pellets LS

Lactose Pellets LS

Lactose Pellets LS

Lactose Pellets LS

Sr. No.

1

2

3

4

5

6

7

8

Mesh Size (ASTM)

18 / 20

20 / 30

30 / 40

40 / 50

50 / 60

60 / 80

80 / 100

100 / 200

Used as spherical seed cores for drug layering & film coating.

Also used in manufacture of granules / beadlets with sustained /

controlled release, taste masking & other special properties.

Diameter In mm (µm)

0,850 – 1,000

–

–

0,300 – 0,425

0,250 – 0,300

–

0,150 – 0,180

–

Application

Ca l c i um Ca rbo na t e P e l l e t s

We do customized special cores / pellets for customers on their annual product requirements.

Grade

Calcium Carbonate Pellets CS -100

Calcium Carbonate Pellets CS-102

Calcium Carbonate Pellets CS-203

Calcium Carbonate Pellets CS-305

Calcium Carbonate Pellets CS-507

Calcium Carbonate Pellets CS-708

Sr. No.

1

2

3

4

5

6

Particle size range (µm)

75 - 212

106 - 212

150 - 300

300 - 500

500 - 710

710 - 850

Used as spherical seed cores for drug layering & film coating.

Also used in manufacture of granules / beads with sustained /

controlled release, taste masking & other special properties.

Diameter In mm (µm)

–

–

–

–

–

–

Disclaimer : This information and our technical advice - whether verbal, in writing or by way of trials - are given in good faith but without warranty, and this also applies where proprietary rights of third parties are involved. Our advice does not release you from the obligation to verify the information currently provided - especially that contained in our safety data and technical information sheets - and to test our products as to their suitability for the intended processes and uses. The application, use and processing our products and the products manufactured by you on the basis of our technical advice are beyond our control and, therefore, entirely your own responsibility.

SPRAYSPHERES™ - CS

l Calcium Carbonate Neutral Pellets consist of CaCO3 and also used for the controlled release and MUPS formulations in nutraceutical and

pharmaceutical medicine.

l Adapted for controlled release or sustained release formulations to produce spherical granules or pellets which have the most suitable size and

dissolution profile.

Calcium Carbonate Pellets Definitions:

l The SPRAYSPHERES™ - CS have been developed using calcium carbonate (90%) as base and other ingredient is maize starch.

l Calcium carbonate complying with Ph. Eur / USP / NF.

l Manufacturing in accordance with the cGMP.

Calcium Carbonate General Properties:

l Nearly white hard, uniform and spherical particles. (sphericity degree average >90%)

l Very low friability level.

l Calcium carbonate high physiochemical inertness improves the stability of the finished product.

l Uniform and consistent loading.

l Calcium give a improved taste and mouth feel for the pellets.

l For PH dependent applications

Calcium Carbonate Particle Size Specifications:

l Minimum of 92% (w/w) of SPRAYSPHERES™ - CS are between the lower and the upper limits of the size stated on the label.

l The SPRAYSPHERS™ - CS selection is obtained by the decreasing size by sieving method.

Calcium Carbonate Application:

l Used as cores to be coated in the manufacture of dry pharmaceutical forms. It enables greater accuracy and consistency in drug layering and

coating.

l Suitable for non-carcinogenic products.

l Ph controlled applications, these starter cores give a specific ph to the dissolution profile.

l Adopted to controlled release or sustained release formulations SPRAYSPHERES™ - CS make it easy to produce spherical micro granules which

have the most suitable size and dissolution profile to each specific purpose.

Application

Disclaimer : This information and our technical advice - whether verbal, in writing or by way of trials - are given in good faith but without warranty, and this also applies where proprietary rights of third parties are involved. Our advice does not release you from the obligation to verify the information currently provided - especially that contained in our safety data and technical information sheets - and to test our products as to their suitability for the intended processes and uses. The application, use and processing our products and the products manufactured by you on the basis of our technical advice are beyond our control and, therefore, entirely your own responsibility.

Ta r t a r i c A c i d P e l l e t s

We do customized special cores / pellets for customers on their annual product requirements.

Grade

Tartaric Acid Pellets TS

Tartaric Acid Pellets TS

Tartaric Acid Pellets LS

Tartaric Acid Pellets TS

Tartaric Acid Pellets TS

Tartaric Acid Pellets TS

Tartaric Acid Pellets TS

Sr. No.

1

2

3

4

5

6

Particle size range (µm)

20 / 30

30 / 40

40 / 50

50 / 60

60 / 80

80 / 100

100 / 200

Used as spherical seed cores for drug layering & film coating.

Also used in manufacture of granules / beads with sustained /

controlled release, taste masking & other special properties.

Diameter In mm (µm)

–

–

–

–

–

–

–

SPRAYSPHERES™ - TS

l Tartaric acid pellets and also used for the controlled release and MUPS formulations in nutraceutical and pharmaceutical medicine.

l Adapted for controlled release or sustained release formulations to produce spherical granules or pellets which have the most suitable size and

dissolution profile.

l Tartaric acid complying with Ph. Eur / USP / NF.

l Manufacturing in accordance with the cGMP.

Tartaric acid General Properties:

l Very low friability level.

l Tartaric acid high physiochemical inertness improves the stability of the finished product.

l Uniform and consistent loading.

l For PH dependent applications

Tartaric acid pellet Application:

l Used as cores to be coated in the manufacture of dry pharmaceutical forms. It enables greater accuracy and consistency in drug layering and

coating.

l Suitable for non-carcinogenic products.

l Ph controlled applications; these starter cores give a specific ph to the dissolution profile.

Ma nni t o l P e l l e t s

We do customized special cores / pellets for customers on their annual product requirements.

Grade

Mannitol Pellets MAS

Mannitol Pellets MAS

Mannitol Pellets MAS

Mannitol Pellets MAS

Mannitol Pellets MAS

Mannitol Pellets MAS

Mannitol Pellets MAS

Mannitol Pellets MAS

Sr. No.

1

2

3

4

5

6

7

8

Mesh Size (ASTM)

18 / 20

20 / 30

30 / 40

40 / 50

50 / 60

60 / 80

80 / 100

100 / 200

Used as spherical seed cores for drug layering & film coating.

Also used in manufacture of granules / beadlets with sustained /

controlled release, taste masking & other special properties.

Diameter In mm (µm)

0,850 – 1,000

–

–

0,300 – 0,425

0,250 – 0,300

–

0,150 – 0,180

–

Application

Application

SPRAYSPHERES™ - MAS

Manitol Pellets Definitions:

l

l Produced in accordance with the cGMP.

l Completely for water soluble application a substitute for sugar.

Application:

l Suitable for very low / high dosage forms and for drugs with a low therapeutic margin.

l Used as cores to be coated in the manufacture of highly hygroscopic / soluble drugs / unstable drug.

l Using SPRAYSPHERES™ - MAS can be converted to ready to fill pellet technology.

l Starter cores for Delayed release / Sustained release / time release / pulse release / Controlled release & Immediate release applications, etc.

Manitol spheres contain more than 80 percent of Manitol. Calculated on the dried basis. The dried basis. The remainder consists of Starch.

S i l i c a P e l l e t s

SPRAYSPHERES™ - AS

Silica Pellets Neutral pellets Consist of SiO2 and mainly used as a core for drug loading of insoluble and instable drug. Also used in MUPS

technology.

Silica Pellets Definitions:

l The SPRAYSPHERES™ - AS have been developed using Silicon dioxide (< 75%) as base.

l Silica complying with Ph. Eur / USP / NF.

l Manufacturing in accordance with the cGMP.

Silica Pellets General properties:

l Nearly white hard, uniform and spherical particles. (Sphericity degree average >90%)

l Very low friability level.

MCC Pe l l e t s

SPRAYSPHERES™ - MS

Microcrystalline Cellulose Pellets Neutral pellets for sugar free products, highly soluble & controlled released formulation products.

MCC Pellets Definitions:

l The SPRAYSPHERES™ - MS have been developed using microcrystalline cellulose (MCC) as base.

l Microcrystalline cellulose is purifies, partly devolymerised cellulose, prepared from alpha cellulose.

l MCC complying with Ph. Eur.

l Manufacturing in accordance with the cGMP.

MCC Pellets General properties:

l Nearly white hard, uniform and spherical particles. (Sphericity degree average >90%)

l Very low friability level.

l MCC high physiochemical inertness improves the stability of the finished product.

l Insoluble in water, absolute ethanol, acetone.

We do customized special cores / pellets for customers on their annual product requirements.

Grade

Silica Pellets AS-100

Silica Pellets AS-102

Silica Pellets AS-203

Silica Pellets AS-305

Silica Pellets AS-507

Silica Pellets AS-708

Sr. No.

1

2

3

4

5

6

Particle size range (µm)

75 - 212

106 - 212

150 - 300

300 - 500

500 - 710

710 - 850

Used as spherical seed cores for drug layering & film coating.

Also used in manufacture of granules / beads with sustained /

controlled release, taste masking & other special properties.

Diameter In mm (µm)

–

–

–

–

–

–

Application

We do customized special cores / pellets for customers on their annual product requirements.

Grade

MCC Pellets MS-100

MCC Pellets MS-102

MCC Pellets MS-203

MCC Pellets MS-305

MCC Pellets MS-507

MCC Pellets MS-708

Sr. No.

1

2

3

4

5

6

Particle size range (µm)

75 - 212

106 - 212

150 - 300

300 - 500

500 - 710

710 - 850

Used as spherical seed cores for drug layering & film coating.

Also used in manufacture of granules / beads with sustained /

controlled release, taste masking & other special properties.

Diameter In mm (µm)

–

–

–

–

–

–

Application

Disclaimer : This information and our technical advice - whether verbal, in writing or by way of trials - are given in good faith but without warranty, and this also applies where proprietary rights of third parties are involved. Our advice does not release you from the obligation to verify the information currently provided - especially that contained in our safety data and technical information sheets - and to test our products as to their suitability for the intended processes and uses. The application, use and processing our products and the products manufactured by you on the basis of our technical advice are beyond our control and, therefore, entirely your own responsibility.

Disclaimer : This information and our technical advice - whether verbal, in writing or by way of trials - are given in good faith but without warranty, and this also applies where proprietary rights of third parties are involved. Our advice does not release you from the obligation to verify the information currently provided - especially that contained in our safety data and technical information sheets - and to test our products as to their suitability for the intended processes and uses. The application, use and processing our products and the products manufactured by you on the basis of our technical advice are beyond our control and, therefore, entirely your own responsibility.

We do customized Projects / Development for customer based on their annual requirement of the product. Pellets from 50 - 2500 micron sizes possible.

Neutral Excipients

Spraypol L-30D-55

Spraypol E-100

Spraypol EPO

Spraypol L-100

Spraypol S-100

Sr. No.

1

2

3

4

5

Percentage (%)

30.00%

100%

100%

100%

100%

Therapeutical

Polymer for enteric coating

Polymer for enteric coating

Polymer for enteric coating

Polymer for enteric coating

Polymer for enteric coating

PH Release

PH 7.5 - 5

PH 1 - 1.5

PH 1 - 1.5

PH 6 - 7

PH up to 7.5

A c ry l i c Co a t i ng Po l y mer

Application: Drug delivery in Jejunum.

Functionality: Anionic polymer of methacrylic acid and ethacrylates with -COOH functional groups.

L - 30 D - 55

Application: Taste and odour masking, insolating coating, transdermal applications, moisture protection.

Functionality: Cationic polymer with dimethylaminoethyl ammonium functional groups.

E - 100

Application: Taste and odour masking, Insolating coating, transdermal applications, moisture protection.

Functionality: Cationic polymer with dimethylaminoethyl ammonium functional groups.

EPO

Application: Drug delivery in Jejunum.

Functionality: Anionic polymer of methacrylic acid and ethacrylates with -COOH functional groups.

L - 100

Application: Drug delivery in Jejunum.

Functionality: Anionic polymer of methacrylic acid and ethacrylates with -COOH functional groups.

S - 100

DUODENUM PH > 5.5

SPRAYPOL L 30 D-55

JEJUNM PH 6-7

TIME CONTROLLEDSUSTAINED RELEASE

SPRAYPOL L 100COLON ASCENDENS PH 6-7

SPRAYPOL S 100

IIEUM PH UP TO 7.5

SPRAYPOL S 100

STOMACH PH 1- 1.5

SPRAYPOL E 100

SPRAYPOL EPO

Survey No. 146, H. No.1 (PT),

Vasai Phata Highway Junction, Pelhar,

Nh8, Vasai (E) - 401 208, Maharashtra (India).

Tel. : (+91-22) 30018900 / 30018915 - 98

Mob. : (+91) 986 723 6594

Fax : (+91-22) 30018908 / 30018913

E-mail : umang@umangpharmatech.com

Today the company has three major divisions: Personal care, Bakery and food ingredients, Pharmaceutical division for innovative dosage form development.

Websites:www.umangpharmatech.comwww.umangengineering.comwww.extruderspheronizer.com

Umang Pharmatech Pvt. Ltd. A truly global organization...

Today the company has three major divisions: Personal care, Bakery and food ingredients, Pharmaceutical division for innovative dosage form development.

Websites:www.concept-machines.comwww.coating-machines.com

Today the company has three major divisions: Personal care, Bakery and food ingredients, Pharmaceutical division for innovative dosage form development.

Websites:www.umangpharma.comwww.cosmeticbeads.com

Today the company has three major divisions: Personal care, Bakery and food ingredients, Pharmaceutical division for innovative dosage form development.

Websites:www.umangpharma.comwww.edibleglitters.comwww.ediblefilm.co.uk

Today the company has three major divisions: Personal care, Bakery and food ingredients, Pharmaceutical division for innovative dosage form development.

Websites:www.umangpharmaceuticals.comwww.pharmaceuticalpellets.comwww.pharma-spheres.com

Today the company has three major divisions: Personal care, Bakery and food ingredients, Pharmaceutical division for innovative dosage form development.

Websites:www.umangpharmaceuticals.comwww.micro-pellets.comwww.pharma-spheres.com

Umang was incepted in the year 1982, with an objective to serve the clients with all kinds of equipments and accessories under one roof.

Within a very short span of time, we succeeded to be the most reliable brand name in the market supplying equipments and solutions to the

Pharmaceutical industry for Pelletization and granulation solutions.

In 2007, the company ventured into solutions for Personal care industry majorly focusing on Oral care products, giving encapsulated

ingredients for cooling applications. In 2009, the company further integrated itself to give solutions for Bakery and food applications like

Chewing gum, mouth dissolving films etc. Today the company has three major divisions: Personal care, Bakery and food ingredients,

Pharmaceutical division for innovative dosage form development like geletain beads, Edible films, innovative encapsulation applications.

© 2012. All rights reserved.

Pelletization and Edible Film Solutions Concept Range

Personal Care and Detergents Bakery and Food Decoration

Pharmaceutical and Nutraceutical Neutral Pellets and Coating Polymers