UCSD CSRRP(Clinician-Scientst Radiology Residency Program)

Overview for Applicants

Program Co-Directors

Claude B. Sirlin, M.D.Diagnostc Radiology

csirlin@ucsd.edu

Isabel Newton, M.D., Ph.D.Interventonal Radiology

inewton@ucsd.edu

Beverly Sastri, M.B.ADept. of Radiologybsastri@ucsd.edu

Administrator

Vision

• Our vision for our program: • To become the best radiology research residency

training program in U.S.

• Our vision for you: • To prepare you as a radiology clinician-scientst

• Fundable as independent PI or co-investgator in team science 2

Missions

3

• Train clinician-scientsts in radiology

• Cultvate their career development and growth

• Nurture a passion for academics

Motivation• Clinician scientsts needed to lead contnued progress of radiology

• Talent is not enough, supplemental training is required

4Commercial Loan Broker Training Program

Program Philosophy

5

• Botom up

• Teamwork, camaraderie, support

Program Design

• Maximize research tme, opportunites, success

• Clinical training

• Leadership experience

• Teamwork and empowerment

6

ProtectedResearch

12 Months ** * ** * ** * ** *

* 6 weeks per year, usually as three 2-week blocks

R1 Year R2 Year R3 Year R4 Year R5 Year

RESEARCH & CLINICAL TRAINING

(IR/DR PATHWAY)

R6 Year

Advanced IR training

Advanced IR training

ClinicalRadiology

DR or IR/DR Pathway Rotatons, plus Clinical Curriculum Lectures, Interdisciplinary Conferences, Educatonal Courses

DR or IR/DR Pathway Rotatons, plus Clinical Curriculum Lectures, Interdisciplinary Conferences, Educatonal Courses

Program Design

One year of protected research up front

6 weeks of protected research in each of the clinical years

Rigorous clinical training for next 4 years

New!

EncouragedEncouraged

ContnueContnueRefine and update IDP through structure mentorship

(see below)Formulate

IDPIndividual

Development Plan

EncouragedEncouragedTraining in

Ethics & RigorFormal courses

ContnueContnueStructured Mentorship

R1 Year R2 Year R3 Year R4 Year R5 Year

CAREER DEVELOPMENT (IR/DR PATHWAY)

R6 Year

MonthlyWorkshops

ChiefResidency

Meetngs w/ Dept. Chair & PDs to plan fellowship/beyond

Complete K-, R-, or equivalent grant applicaton

Society grant applicaton

ContnueContnueStrategic

Career Planning

EncouragedEncouragedScientfic Meetngs

& Presentatons

LeadershipTraining

EncouragedEncouragedGrant Writng

Course

Outreach & Diversity

Outreach Leader

Reinforcement of formal courses through workshops (see above), mentor’s lab meetngs, and supplementary training

Regular meetngs with scientfic mentors, career mentors, and PDs to discuss progress and solve problems, using IDPs (see above) as cornerstone

Trainees atend ≥ 1 scientfic meetng in R1 year and ≥ 1 scientfic meetng in R2-R5 years, give ≥ 1 department-wide scientfic presentaton each year

EncouragedEncouraged

ContnueContnueRefine and update IDP through structure mentorship

(see below)Formulate

IDPIndividual

Development Plan

EncouragedEncouragedTraining in

Ethics & RigorFormal courses

ContnueContnueStructured Mentorship

R1 Year R2 Year R3 Year R4 Year R5 Year

CAREER DEVELOPMENT (IR/DR PATHWAY)

R6 Year

MonthlyWorkshops

CSRRP ChiefResidency

Meetngs w/ Dept. Chair & PDs to plan fellowship/beyond

Complete K-, R-, or equivalent grant applicaton

Society grant applicaton

ContnueContnueStrategic

Career Planning

EncouragedEncouragedScientfic Meetngs

& Presentatons

LeadershipTraining

EncouragedEncouragedGrant Writng

Course

Outreach & Diversity

Outreach Leader

Reinforcement of formal courses through workshops (see above), mentor’s lab meetngs, and supplementary training

Regular meetngs with scientfic mentors, career mentors, and PDs to discuss progress and solve problems, using IDPs (see above) as cornerstone

Trainees atend ≥ 1 scientfic meetng in R1 year and ≥ 1 scientfic meetng in R2-R5 years, give ≥ 1 department-wide scientfic presentaton each year

Town Hall Meetings

EncouragedEncouraged

ContnueContnueRefine and update IDP through structure mentorship

(see below)Formulate

IDPIndividual

Development Plan

EncouragedEncouragedTraining in

Ethics & RigorFormal courses

ContnueContnueStructured Mentorship

R1 Year R2 Year R3 Year R4 Year R5 Year

CAREER DEVELOPMENT (IR/DR PATHWAY)

R6 Year

MonthlyWorkshops

CSRRP ChiefResidency

Meetngs w/ Dept. Chair & PDs to plan fellowship/beyond

Complete K-, R-, or equivalent grant applicaton

Society grant applicaton

ContnueContnueStrategic

Career Planning

EncouragedEncouragedScientfic Meetngs

& Presentatons

LeadershipTraining

EncouragedEncouragedGrant Writng

Course

Outreach & Diversity

Outreach Leader

Reinforcement of formal courses through workshops (see above), mentor’s lab meetngs, and supplementary training

Regular meetngs with scientfic mentors, career mentors, and PDs to discuss progress and solve problems, using IDPs (see above) as cornerstone

Trainees atend ≥ 1 scientfic meetng in R1 year and ≥ 1 scientfic meetng in R2-R5 years, give ≥ 1 department-wide scientfic presentaton each year

CSRRP End of Year Parties

Mentorship is a key component

• 1 or 2 lab mentors

• Career development mentor

11

Anders Dale Cynthia Santillan David Kleinfeld

Delores Pretorius Eric Ahrens Eric Chang Graeme Bydder

Haydee Ojeda Isabel Newton Jiang Du Mingxiong Huang

Nathan Gianneschi Richard Buxton Roland Lee Thomas Liu

Claude Sirlin

Current Mentors

David Vera

Bob Mattrey

Albert Hsiao

Translational research is emphasiȣed

• Translational imaging research

• Knowledge of human biology develop & validate imaging technologies

• Observatons in humans understand biological underpinnings

12

• Modalities: MRI, CT, US, PET, NM, optcs, MEG, MRI-PET (planned)

• Models: animals, humans

• Organ systems: neuro, cardiac, vascular, pulmonary, GI, GU, MSK

• Processes: cancer, aging, metabolic dz, infamm dz, degeneraton,…

• Research: targeted agents, instrumentaton, sofware, validaton, …

• Depts: Radiology, Cell/Molec Biol, Bioengineering, Physics,…

• Institutes: UCSD, Salk, Sanford-Burnham, Scripps, Novarts13

Many research options are available

We ofer wide-ranging workshopsTopics• Leadership

• Career development, career development awards

• Starting and running a lab

• Success in academics

• Collaboration/networking

• Patents

• Commercialiȣation: industrial relationships, start-ups

• Grant writing

• Manuscript writing

• Ethics

• YOU decide14

Speakers• David Brenner (dean of

medical school)

• Alex Norbash (chair of radiology)

• Chairs of other departments

• Scot Lippman (director of cancer center

• Basic scientists

• Clinician scientists

• YOU decide

15

Julie Bykowski MD

Ed Wong MD/PhD

2010

David Karow MD/PhD

Takeshi YokooMD/PhD

2011

Isabel NewtonMD/PhD

Mat CroninMD

2012

Alan ChiangMD/PhD

Moh Eghtedari MD/PhD

2013

Sid TavriMD

August Tuan MD/PhD

Farshad MoradiMD/PhD

2014

Michael HahnMD/PhD

Rahul DesikanMD/PhD

2015

Paul MurphyMD/PhD

Emmi OlsonMD/PhD

David HeisterMD/PhD

2016

Chris MaloneMD

Rebecca RakowMD/PhD

2017

Kaȣim Narsinh MD

Nineteen CSRRP residents have graduated

16

Ghiam Yamin MD/PhD

Andrew SungMD

Yr4

Jun Rho MD

James Tom MD/PhD

Neal Corson MD/PhD

Brendon Bagley MD

Yr3

Yr2

Kal RestomMD/MS

Vipul ShethMD/PhD

Alex VeȣeridisMD/PhD

Yr5

Souda FaȣeliMD/MPH

Amin JahromiMD/PhD

William HongMD/MS

Yr1

Tara RetsonMD/MhD

Kang WangMD/PhD

Adam SearlemanMD/PhD

Fifeen CSRRP residents are in the program now

Our trainees do cutting-edge research and land great fellowships and faculty positions

Alumni ‘06 ‘07 ‘08 ‘09 ‘10 ‘11 ‘12 ‘13 ‘14 ‘15 ‘16 ‘17 ‘18 ‘19 ‘20 ‘21 ‘22

2010 Julie Bykowski MD

Ed Wong MD/PhD

2011 David Karow MD/PhD

Takeshi Yokoo MD/PhD

2012 Matt Cronin MD

Isabel Newton MD/PhD

2013 Alan Chiang MD/PhD

Moh Eghtedari MD/PhD

2014 Farshad Moradi MD/PhD

Sid Tavri MD

August Tuan MD/PhD

2015 Rahul Desikan MD/PhD

Mike Hahn MD/PhD

2016 David Heister MD/PhD

Paul Murphy MD/PhD

Emmi Olson MD/PhD

2017 Kazim Narsinh MD

Chris Malone MD

Rebecca Rakow MD/PhD

UCSD NeuroUCSD NeuroBrain ASLBrain ASL UCSDUCSD

MMP ImagingMMP Imaging Private PracticePrivate Practice

MEGMEG UPUP UP NeuroUP Neuro

Stem Cell Labeling Stem Cell Labeling MGHMGH Case West. IRCase West. IR

Pulmonary ASLPulmonary ASL MiamiMiami Private PracticePrivate Practice

Cancer Stem CellsCancer Stem Cells UCSDUCSD UCSD IRUCSD IR

Susceptibility MRISusceptibility MRI UCSFUCSF Private PracticePrivate Practice

Acousto-OpticsAcousto-Optics UCSDUCSD UCSD BreastUCSD Breast

MRI Fatty LiverMRI Fatty Liver MGHMGH UTSW BodyUTSW Body

Self-assembling probes Self-assembling probes UCSDUCSD UCSD BodyUCSD Body

fMRIfMRI UCSD NucsUCSD Nucs

US molecular imagingUS molecular imaging

DWI modelingDWI modeling UCLAUCLA UCSDUCSD

MEG brain traumaMEG brain trauma UCSDUCSD PPPP

MRI DementiaMRI Dementia UCLAUCLA UCSD BodyUCSD Body

MRI DementiaMRI Dementia UCSFUCSF UCSFUCSF

H2O2 ImagingH2O2 Imaging UWUW

MRI Stem CellsMRI Stem Cells UPUP

DWI Breast CancerDWI Breast Cancer UCSDUCSD

Clinician-Scientist Program:

Current Trainees ‘06 ‘07 ‘08 ‘09 ‘10 ‘11 ‘12 ‘13 ‘14 ‘15 ‘16 ‘17 ‘18 ‘19 ‘20 ‘21 ‘22

2018 Kal Restom MD/MS

Vipul Sheth MD/PhD

Alex Vezeridis MD/PhD

2019 Andrew Sung MD

Ghiam Yamin MD/PhD

2020 Brendon Bagley MD

Jun Rho MD

James Tom MD/PhD

Neal Corson MD/PhD

2021 Souda Fazeli MD/MPH

William Hong MD/MS

Amin Jahromi MD/PhD

2022 Tara Retson MD/PhD

Adam Searleman MD/PhD

Kang Wang MD/PhD

UTE multiple sclerosisUTE multiple sclerosis

Nanotechnology imagingNanotechnology imaging

Pulmonary ASLPulmonary ASL

DWI prostate cancerDWI prostate cancer

Brain ASLBrain ASL

MRI cell trackingMRI cell tracking

Neurovasc. couplingNeurovasc. coupling

MEGMEG

DWI renal cancerDWI renal cancer

MRI liver diseaseMRI liver disease

F-19 MRI inflammationF-19 MRI inflammation

Patient reported outcomesPatient reported outcomes

AI for Cardiac DiseaseAI for Cardiac Disease

UTE MRIUTE MRI

AI for Liver DiseaseAI for Liver Disease

• Over 200 peer-reviewed articles

• 17 of the 32 trainees have received at least one grant

• over $3.9M in cumulative funding

• 14 of 32 trainees have received the prestgious RSNA research resident grant, including all 3 first-year CSRRP trainees in 2017!

• 19 residents graduated by 2017:

• 10 in academic faculty positions

• 3 in fellowship

Resident Accomplishments as of 2017

19

T32 Award – 7/07-6/12 T32 Award – 7/13-6/18

Program Timeline

~3 residents/year

20

0

3

6

9

12

15

'05 '06 '07 '08 '09 '10 '11 '12 '13 '14 '15 '16 '17 '18 '19 '20 '21

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