Turku PET Centre

Turku PET Centre

EXTRACTING ARTERIAL BLOOD CURVE FROM PET IMAGE - UPDATE

Abdominal aorta in [15O]H2O studies

05/08/23 Turku PET Centre

Improved method

• Method contains– 95% thresholding– Recovery coefficient

• User has to specify the range of planes• Initial value for diameter is not needed

05/08/23 Turku PET Centre

Thresholding

• For each frame– Find the pixel with maximum activity (inside the vessel)– Include all pixels where activity value is greater than

0.95*maximum activity (=thresholding)– Calculate mean

=> thresholded TAC

05/08/23 Turku PET Centre

Recovery coefficient

• Estimate diameter of the vessel• Calculate the recovery coefficient

2

2

2*2.3551

R

FWHM

RC e

05/08/23 Turku PET Centre

Resulting input TAC

RC * thresholded TAC

05/08/23 Turku PET Centre

Diameter estimates (mm)

subject 04064 04066 04079 04085 04104 04106 04122 04132plane3 14.84 14.15 18.76 13.27 17.98 16.39 16.910 15.1 16.3 16.711 16.6 16.8 16.7 13.0 16.4 16.812 15.2 15.2 13.9 14.0 11.7 15.413 15.5 15.1 13.2 15.6 18.2 17.6 14.4 18.214 14.1 13.8 14.3 14.9 13.7 14.0 14.8 16.415 17.2 14.6 15.5 15.9 15.0 12.1 16.4 16.4mean 15.60753 15.10586 14.71063 14.94992 15.63047 15.42950 15.57845 16.99924median 15.33046 15.06145 14.34608 15.26634 14.98045 16.29435 15.44876 16.44909sd 1.121504 1.106532 1.388988 1.263116 2.308937 2.247811 1.031579 1.00873

05/08/23 Turku PET Centre

Result TACs

05/08/23 Turku PET Centre

AUC correlations

050001000015000200002500030000350004000045000

0 10000 20000 30000 40000 50000

AUC (blood pump TAC)

AU

C (i

mag

e in

putT

AC

)

05/08/23 Turku PET Centre

Future plans

• Article dealing with input extraction• Validation of diameter estimates with help of

ultrasound results• Comparisons with ICA