TOLIVS: A Typology Of Loss In Vaccine Supply Chains

Ioannis Daskalopoulos, Stephen Hailes, UCL

George Roussos, Birkbeck College, University of London

Tony Delamothe, British Medical Journal

Mohamed Ahmed, UCL

Leo Brown, Peter Eyres, Netfuse

Contact i.daskalopoulos@ucl.ac.uk

• Founded in 2000, 370mln children vaccinated.

• From manufacture to use between 5% and 50% loss in vaccines

• Urgency in drastically reducing loss

• Diseases do not respect borders

The GAVI Alliance

The Vaccine Supply Chain• Infrastructure Limitations

The Vaccine Supply Chain• Organisational Challenges

– EVM (The Effective Vaccine Management)

– HERMES (Highly Extensible Resource for Modelling Supply Chains)

• Robust Vaccine Tracking System– Improve data quality, quantity, reliability and timeliness

• Operation Along the Chain of Delivery

• Cloud based Information Management

TOLIVS Project

TOLIVS Architecture

ublox c027 Internet of Things Platform

Storage Movement Temperature

APNGateway

Global Roaming

JSON over UDP

Amazon EBS

Device Transport Cloud

TOLIVS Project

TOLIVS Project

TOLIVS Project

15:16:23 15:44:32 16:11:08 16:44:37 17:13:41 17:42:00 18:09:43 18:40:16 19:50:32 20:16:17 20:44:24 21:11:17 21:38:17 22:07:11 22:33:14 22:57:58 23:25:400

5

10

15

20

25

30

Temperature Variation

Time of measurement

Tem

pera

ture

oC

• Working Experimental Prototypes

• Power management

• Deployment with real shipments

• Proposal based on acquired information

TOLIVS Project

Special Thanks• Andrew Garnett, WHO, UNICEF, PATH• Paul Colrain, Jan Grevendonk, WHO• Sophie Newland, PATH• Joannie Robertson, Patrick Lydon, GAVI• Prof Heather Zar, Red Cross War Memorial Childrens Hospital

Cape Town• Dr Raul Isturiz, Dr David Coles, Pfizer• Abdigani Diriye, IBM Research – Catholic University of Eastern

Africa• Dakota Gruener, Oliver Wyman• Rae Harbird, Jan Medvesek, UCL• Marc Castello, uBlox• Steve Brewer, ITaaU+

TOLIVS Project