THE SWOLLEN OPTIC DISC IN CHILDHOOD Differencial Diagnosis · The Swollen Optic Disc in Childhood...
Transcript of THE SWOLLEN OPTIC DISC IN CHILDHOOD Differencial Diagnosis · The Swollen Optic Disc in Childhood...
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THE SWOLLEN OPTIC DISC IN CHILDHOOD
Differencial Diagnosis
GEORGIA CHROUSOS, M.D
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The Swollen Optic Disc in Childhood
• “Optic disc swelling “ and “optic disc edema” are used interchangably
• Papilledema means optic disc swelling due to elevated intracranial pressure
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The Swollen Optic Disc in Childhood
• “Optic disc elevation” is a common referral
• The nature of the underlying disorder can often be predicted from the wording of the referring physician’s phone call
- bil., with headaches and normal vision?
- optic disc swelling and acute visual loss?
- Blurring of the nasal disc margins noted as an incidental finding in an otherwise healthy child?
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The Swollen Optic Disc in Childhood
I. INCREASED INTRACRANIAL PRESSURE
II. OPTIC NEURITIS
III. OPTIC NERVE TUMORS
IV. PRIMARY OCULAR DISEASES
V. SYSTEMIC DISORDERS
VI. PSEUDOPAPILLEDEMA
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The Swollen Optic Disc in Childhood
I. INCEASED INTRACRANIAL PRESSURE
1. INTRACRANIAL MASS LESION
2. PSEUDOTUMOR CEREBRI ( IDIOPATHIC
INTRACRANIAL HYPERTENSION)
Papilledema
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The Swollen Optic Disc in Childhood -papilledema
I. INCREASED INTRACRANIAL PRESSURE
• Normal vision
• Headaches ( frequently present upon
awakening )
• Transient visual obscurations
• Nausea, vomitting
• Diplopia, when present, is usually
due to a 6th CN palsy
Papilledema
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The Swollen Optic Disc in Childhood
I. INCREASED INTRACRANIAL PRESSURE
• Bil.optic disc edema
• Venous distension
• Partial obscuration of the major retinal vessels
• Hyperemia of the disc
• Partial or complete oblitaration of the cup
• Absent venous pulsations
• Flame-shaped hemes
• Cotton wool spots
Papilledema
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The Swollen Optic Disc in Childhood
I. INCREASED INTRACRANIAL PRESSURE
Papilledema
w/up
MRI ( not a CT !!)
CSF opening pressure/analysis
MR Venogram
Other
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The Swollen Optic Disc in Childhood
I. INCREASED INTRACRANIAL PRESSURE
Pseudotumor cerebri ( Idiopathic Intracranial Hypertension)
1. Primary (no recognized cause)
2. Secondary ,associated with:
• Neurological disease (dural venous
sinus thrombosis ) Hx of trauma?
• Systemic diseases (severe anemia)
•
Medications(
corticosteroids,tetracyclin, Vitamin A
intoxication)
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The Swollen Optic Disc in Childhood
I. INCREASED INTRACRANIAL PRESSURE
Pseudotumor cerebri ( Idiopathic Intracranial Hypertension)
1. Sex ratio in children 1:1
2. Obesity not a factor under age 10
yrs
3. Headaches not always present
1. Spontaneous remission commom
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The Swollen Optic Disc in Childhood
II. OPTIC NEURITIS ( post-infectious, MS, ADEM)
• Bil. or unilateral
• Decreased vision • Optic nerve swelling
• Discomfort / pain with extraocular movements
• Decreased color perception
• Visual fields scotomas
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The Swollen Optic Disc in Childhood
II. OPTIC NEURITIS
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The Swollen Optic Disc in Childhood
• Slight to moderate decrease of vision
• Macular star
NEURORETINITIS
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The Swollen Optic Disc in Childhood
III. OPTIC NERVE TUMORS
Optic nerve gliomas
• decreased vision
• proptosis
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The Swollen Optic Disc in Childhood
IV. PRIMARY OCULAR DISEASES
• Intraocular inflammation and hypotony
- juvenile rheumatoid arthritis
- sarcoidosis
- pars planitis
• Traumatic optic neuropathy
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The Swollen Optic Disc in Childhood
V. SYSTEMIC DISORDERS
• Diabetic papillopathy
• Malignant Hyrertension
• Sarcoidosis
• Leukemia
• Other
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The Swollen Optic Disc in Childhood
VI. PSEUDOPAPILLEDEMA
. Optic Nerve Drusen
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The Swollen Optic Disc in Childhood
VI. PSEUDOPAPILLEDEMA
Optic Nerve Drusen Drusen: German word ,originally meant tumor or swelling
• Elevated disc (in children primarily burried drusen)
• Scalloped margins
• Elimination of the cup
• Anomalous disc vasculature
• Less commonly a peripapillary heme
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The Swollen Optic Disc in Childhood
VI. PSEUDOPAPILLEDEMA
Optic Nerve Drusen
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The Swollen Optic Disc in Childhood
VI. PSEUDOPAPILLEDEMA
Optic Nerve Drusen
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OCT
NORMAL
DRUSEN
PAPILLEDEMA
Arch Ophthalmol 2009;127(1):45-49
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The Swollen Optic Disc in Childhood
Papilledema Optic nerve drusen
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The Swollen Optic Disc in Childhood
VI. PSEUDOPAPILLEDEMA
.
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THANK YOU!
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The Swollen Optic Disc in Childhood
VI. PSEUDOPAPILLEDEMA
.
“Nasal blurring”
What should you do?
- Nothing ?
- ultrasound ?
- MRI ?
- LP ?
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Date of download: 10/29/2015 Copyright © 2015 American Medical
Association. All rights reserved.
From: Differentiating Optic Disc Edema From Optic Nerve Head Drusen on Optical Coherence Tomography
Arch Ophthalmol. 2009;127(1):45-49. doi:10.1001/archophthalmol.2008.524
Line scan images with a 4.0-mm diameter (radius, 2.0 mm) that were obtained from the fast optic disc scans on optical coherence
tomography. The images represent a normal optic nerve (A), optic nerve head drusen with moderate (B) and marked (C) elevation,
and optic disc edema with mild (D), moderate (E), and marked (F) elevation, based on the papilledema grading scale of Johnson et
al. The “lumpy-bumpy” internal contour of the optic nerve head in optic nerve head drusen (B), the recumbent “lazy V” pattern of the
subretinal hyporeflective space in optic disc edema (D), and the subretinal hyporeflective space measurement at radii 0.75 mm, 1.5
mm, and 2.0 mm from the optic disc center (E) are depicted.
Figure Legend:
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The Swollen Optic Disc in Childhood
VI. PSEUDOPAPILLEDEMA
. Optic Nerve Drusen
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The Swollen Optic Disc in Childhood
I. INCREASED INTRACRANIAL PRESSURE
Pseudotumor cerebri ( Idiopathic Intracranial Hypertension)