THE NERVOUS SYSTEM PART 1 CHAPTER 11. Nervous System Figure 11.1.
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Transcript of THE NERVOUS SYSTEM PART 1 CHAPTER 11. Nervous System Figure 11.1.
THE NERVOUS SYSTEM
PART 1
CHAPTER 11
Nervous System
Figure 11.1
Nervous System
The master controlling and communicating system of the body
Functions
Sensory input – monitoring stimuli occurring inside and outside the body
Integration – interpretation of sensory input
Motor output – response to stimuli by activating effector organs
Organization of the Nervous System
Central nervous system (CNS)
Brain and spinal cord
Integration and command center
Peripheral nervous system (PNS)
Paired spinal and cranial nerves
Carries messages to and from the spinal cord and brain
5Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Levels of Organization
Sensory (afferent) division
Sensory afferent fibers – carry impulses from skin, skeletal muscles, and joints to the brain
Visceral afferent fibers – transmit impulses from visceral organs to the brain
Motor (efferent) division
Transmits impulses from the CNS to effector organs
Peripheral Nervous System (PNS): Two Functional Divisions
Somatic nervous system
Conscious control of skeletal muscles
Autonomic nervous system (ANS)
Regulates smooth muscle, cardiac muscle, and glands
Divisions – sympathetic and parasympathetic
Motor Division: Two Main Parts
sensorynerves
axons ofmotor nerves
somaticsubdivision
(motor functions)
autonomicsubdivision
(visceralfunctions)
sympathetic
Peripheral Nervous System
para-sympathetic
CentralNervousSystem
brain
spinalcord
AFFERENT EFFERENT
Autonomic nervous system (ANS)
The two principal cell types of the nervous system are:
Neurons – excitable cells that transmit electrical signals
Supporting cells – cells that surround and wrap neurons
Histology of Nerve Tissue
The supporting cells (neuroglia or glial cells):
Provide a supportive scaffolding for neurons
Segregate and insulate neurons
Guide young neurons to the proper connections
Promote health and growth
Supporting Cells: Neuroglia
Most abundant, versatile, and highly branched glial cells
They cling to neurons and their synaptic endings, and cover capillaries
Functionally, they:
Support and brace neurons
Anchor neurons to their nutrient supplies
Guide migration of young neurons
Control the chemical environment
Astrocytes
Astrocytes
Figure 11.3a
Microglia – small, ovoid cells with spiny processes
Phagocytes that monitor the health of neurons
Ependymal cells – range in shape from squamous to columnar
They line the central cavities of the brain and spinal column
Microglia and Ependymal Cells
Microglia and Ependymal Cells
Figure 11.3b, c
Oligodendrocytes – branched cells that wrap CNS nerve fibers
Schwann cells (neurolemmocytes) – surround fibers of the PNS
Satellite cells surround neuron cell bodies with ganglia
Oligodendrocytes, Schwann Cells, and Satellite Cells
Figure 11.3d, e
Oligodendrocytes, Schwann Cells, and Satellite Cells
Structural units of the nervous system
Composed of a body, axon, and dendrites
Long-lived, amitotic, and have a high metabolic rate
Their plasma membrane functions in:
Electrical signaling
Cell-to-cell signaling during development
Neurons (Nerve Cells)
blood vessels
outer connective tissue of one nerve
unsheathed node axon
myelin sheath
many neurons bundled together inside a connective tissue sheath
axon of one neuron
axon
axon endings
cell body
dendrites
axon
cell bodyaxon
endingperipheral axon
receptor endings
Sensory NeuronMotor NeuronInterneuron
cell body
Neurons (Nerve Cells)
Figure 11.4b
Contains the nucleus and a nucleolus
Is the major biosynthetic center
Is the focal point for the outgrowth of neuronal processes
Has no centrioles (hence its amitotic nature)
Has well-developed Nissl bodies (rough ER)
Contains an axon hillock – cone-shaped area from which axons arise
Nerve Cell Body (Perikaryon or Soma)
Armlike extensions from the soma
Called tracts in the CNS and nerves in the PNS
There are two types: axons and dendrites
Processes
Short, tapering, and diffusely branched processes
They are the receptive, or input, regions of the neuron
Electrical signals are conveyed as graded potentials (not action potentials)
Dendrites of Motor Neurons
Slender processes of uniform diameter arising from the hillock
Long axons are called nerve fibers
Usually there is only one unbranched axon per neuron
Rare branches, if present, are called axon collaterals
Axonal terminal – branched terminus of an axon
Axons: Structure
Generate and transmit action potentials
Secrete neurotransmitters from the axonal terminals
Movement along axons occurs in two ways
Anterograde — toward axonal terminal
Retrograde — away from axonal terminal
Axons: Function
Whitish, fatty (protein-lipoid), segmented sheath around most long axons
It functions to:
Protect the axon
Electrically insulate fibers from one another
Increase the speed of nerve impulse transmission
Myelin Sheath
Formed by Schwann cells in the PNS
A Schwann cell:
Envelopes an axon in a trough
Encloses the axon with its plasma membrane
Has concentric layers of membrane that make up the myelin sheath
Neurilemma – remaining nucleus and cytoplasm of a Schwann cell
Myelin Sheath and Neurilemma: Formation
Schwann cell
Myelin Sheath and Neurilemma: Formation
Figure 11.5a-c
Gaps in the myelin sheath between adjacent Schwann cells
They are the sites where axon collaterals can emerge
Nodes of Ranvier (Neurofibral Nodes)
A Schwann cell surrounds nerve fibers but coiling does not take place
Schwann cells partially enclose 15 or more axons
Unmyelinated Axons
Amyotrophic Lateral Sclerosis ALS
Both myelinated and unmyelinated fibers are present
Myelin sheaths are formed by oligodendrocytes
Nodes of Ranvier are widely spaced
There is no neurilemma
Axons of the CNS
White matter – dense collections of myelinated fibers
Gray matter – mostly soma and unmyelinated fibers
Regions of the Brain and Spinal Cord
Structural:
Multipolar — three or more processes
Bipolar — two processes (axon and dendrite)
Unipolar — single, short process
Neuron Classification
Functional:
Sensory (afferent) — transmit impulses toward the CNS
Motor (efferent) — carry impulses away from the CNS
Interneurons (association neurons) — shuttle signals through CNS pathways
Neuron Classification
Comparison of Structural Classes of Neurons
Table 11.1.1
Comparison of Structural Classes of Neurons
Table 11.1.2
Comparison of Structural Classes of Neurons
Table 11.1.3