THE COMPANY

GESAN DESIGNS AND PRODUCES ITS OWN RANGE OF CLINICAL CHEMISTRY REAGENTS

Stable liquid reagents

Bulk or OEM manufacturing

Customized packaging and labelling

Design of rinse solutions for every automa-tic analyzer

Vial size optimization on customer request

Gesan was established in early ’90s. Its early mission was the trading of analytic instrumentation and laboratory products.

The continuos investment for research and development has made Gesan to become a production reality, providing to customer higher quality performances.

Dynamism and fl exibility make Gesan able to follow research and innovations.Our goal is the customer satisfaction, providing products and services at maximum quality levels.

All stages in the production

cycle, from raw materials

supplying to logistics, to sa-

les and service & support,

are managed and controlled

by our QMS (Quality Manage-

ment System), 9001:2000 ISO,

13485:2004 certifi ed.

GESAN IS QUALITY

GESAN IS ENVIRONMENT

The whole production site and

all the activities performed,

are designed in the view of

reducing environmental bur-

dens. The Environment mana-

gement system is 14001:2004

ISO Certifi ed.

Our reagents begin their lifecycle from the best raw materials available on the market..

Gesan owns a double osmosys based on a water purifi cation unit which can reach a conducibility value of 0,2 µS!

All stages, such as design control, order processing, vendor qualifi cation, administration and technical support, are addressed by our QMS, which guarantees strict in-process controls.

The correlation studies performed comparing Gesan reagents results with other reference methods, con-fi rmed very good accuracy and precision of obtained analytical results.

Our product range is designed to sati-sfy all international standards, coerci-ve and not, like IVD european directive (98/97/EC) and the strict requirements of the CE mark.

Gesan specialists debug the appli-cation methods on automatic analyzers avai-lable in the Ge-san QC Laboratory.

Additional commercial automatic analyzer application methods are available on request.

The fi lled and packaged

reagents while waiting

for marketing, are stored

at correct temperature

and humidity conditions

in our warehouse or

refrigerating rooms.

Gesan fi lling plant is able to guarantee higher precision in product measuring and vial integrity.

No more pipets!With Gesan reagents it is enough to put one vial content into another!

Liquid reagents ready to use

Packaging fi ts the real needs of the user

Available either in mono and birea-gent :

R1 and R2 already measured:

Safer for the user

Pipets become useless

Avoid reagent pollution

No errors in working solution preparation

Liquid reagents ready to use

Packaging fi ts the real needs of the

Available either in mono and birea-

R1 and R2 already measured:

Liquid reagents ready to use

Packaging fi ts the real needs of the user

Available either in mono and birea-gent :

R1 and R2 already measured:

ALBUMIN LR ALKALINE PHOSPHATASE LRALT-GPT LRAST-GOT LRAMYLASE LRAMMONIAPANCREATIC AMYLASE LRBILE ACID LRCALCIUM ARSENAZO LRCALCIUM CPC LRDIRECT FREE CALCIUM LRCHLORIDE LRCHOLESTEROL MONOREAGENT LRHDL DIRECT CHOLESTEROL LRLDL DIRECT CHOLESTEROL LRCHOLINESTRASE LRDIBUCAINE LRCK NAC LRCK MB LRCOPPER LRCREATININE LRDIRECT BILIRUBIN LRTOTAL BILIRUBIN LRGAMMA GT LRGLUCOSE MONOREAGENT LR

FRUCTOSAMINE LRG6PDH LYHOMOCYSTEINE LRIRON LRLDH LRLACTATO (LYO)LIPASE LRLITHIUM LYMAGNESIUM LRPHOSPHORUS LRPOTASSIUM LRSODIUM LRTOTAL PROTEIN LRTRIGLYCERIDES MONOREAGENT LRUREA UV LRURIC ACID MONOREAGENT LRZINC LRBICARBONATE (CO2)ALCOHOL TOTAL LIPIDS LRURINARY PROTEINS LRASOCRPRFIgA

IgGIgMIgE C3C4α-ACID GLICOPROTEINAPO A1APO BFERRITINTRANSFERRINα-2 MACROGLOBULINβ2 MICROGLOBULINα-1 ANTITRYPSINANTITROMBIN IIILP(a)APTOGLOBINFIBRINOGENMICROALBUMINHbA1c direct PHENOBARBITAL CRP UHS KAPPA CHAIN λ CHAIN

MANUAL SEROLOGIC TEST LATEX GESAN

RHEUMATOLOGY

Antistreptolysin A.S.O.

C-Reactive protein

R.F. Rheumatoid Factor

SYPHILIDE

ANTIGEN VDRL

R.P.R

TPHA

VARIOUS

BETA-HCG sensibility: 300Ul/L

INFECTIOUS MONONUCLEOSIS

LUPUS ERYTHEMATOSUS

WAALER ROSE

EMOSTASIS REAGENTS

ACTIVATED P.T.T

CALCIUM CLORURE

CALCIUM THROMBOPLASTIN “S” ISI 1.1-1.2

FIBRINOGEN

NORMAL PLASMA

PATOLOGIC PLASMA

WASHING SOLUTION FOR AUTOMATED ANALYZERS

CONCENTRATED WASHING SOLUTION

OPTICAL CELL WASH

CALIBRATORS AND CONTROLS ARE AVAILABLE FOR ALL METHOD

CLINICAL CHEMISTRY REAGENTS LIST

All our diagnostics are liquid, CE marked pre measured

and guarantee the strictly compliance with European IVD regulations.

Upon request, we are able to producebulk diagnostic and

kit in OEM or in customized packaging

200 VETERINARY DEDICATED KITS

PRODUCT METHOD CODENUMBER OF TEST

ALBUMIN LR BCG BROMOCRESOL GREEN

C1200150V 160

ALKALINE PHOSPHATASE LR

DEA DGKC C3000120V 70

ALT-GPT LR KINETIC UV OPTIMIZED IFCC

C3800120V 80

AST-GOT LR KINETIC UV OPTIMIZED IFCC

C3700120V 80

AMYLASE LR CNPG3 C1400110V 40

BILE ACIDS LR ENZYMATIC C1100140V 135

CALCIUM ARSENAZO LR ARSENAZO III C1850120V 70

CHLORIDE LR MERCURIOUSTHIOCYANATE

C2100120V 80

CHOLESTEROL LR CHOD-PAP C2230150V 160

DIRECT HDL CHOLESTEROL LR

CLEARANCE C2210120V 60

DIRECT LDL CHOLESTEROL LR

CLEARANCE C2220120V 60

CHOLINESTERASE LR HEXACYANOFERRATE III

C2500120V 90

CK NAC LR KINETIC OPTIMIZED DGKC-IFCC

C1900120V 80

CREATININE LR JAFFE’ C2700210V 80

COPPER LR Di Br Paesa C4600130V 95

PRODUCT METHOD CODENUMBER OF TEST

DIRECT BILIRUBIN LR JENDRASSIK-GROF MO-DIFIED

C1700120V 80

FRUCTOSAMINE LR NBT C3400110V 30

GAMMA GT LR SZASZ C3500120V 90

GLUCOSE LR GOD-POD C3650150V 160

IRON LR FERENE C2900120V 80

LDH LR KINETIC OPTIMIZED SCE

C4000120V 80

LACTATE ENZYMATIC LO-POD C4100110V 35

LIPASE LR TURBIDIMETRIC C4750150V 190

MAGNESIUM LR XYLIDIYL BLUE C4400120V 80

PHOSPHOROUS LR BLUE MOLYBDATE C3300120V 80

POTASSIUM LR TURBIDIMETRIC C4900120V 90

SODIUM ENZYMATIC C4950140V 150

TOTAL BILIRUBIN LR JENDRASSIK-GROF MO-DIFIED

C1600120V 80

TOTAL PROTEIN LR BIURET C4500120V 60

TRYGLICERIDES LR GPO-PAP C4730150V 160

UREA UV LR KINETIC UV UREASE-GLDH

C4800150V 160

URIC ACID LR URICASE POD-PAP C1000150V 215

URINARY PROTEINS LR PYROGALLOL RED C4550120V 60

PHENOBARBITAL LR TURBIDIMETRIC C5600120V 90

CRP VET LR TURBIDIMETRIC C710VET 200

CHOLESTEROL LRCLEARANCE C2220120V 60

CHOLINESTERASE LR HEXACYANOFERRATE III

C2500120V 90

CK NAC LR KINETIC OPTIMIZED DGKC-IFCC

C1900120V 80

CREATININE LR JAFFE’ C2700210V 80

COPPER LR Di Br Paesa C4600130V 95

TRYGLICERIDES LR GPO-PAP C4730150V 160

UREA UV LR KINETIC UV UREASE-GLDH

C4800150V 160

URIC ACID LR URICASE POD-PAP C1000150V 215

URINARY PROTEINS LR PYROGALLOL RED C4550120V 60

PHENOBARBITAL LR TURBIDIMETRIC C5600120V 90

CRP VET LR TURBIDIMETRIC C710VET 200

200 DEDICATED KITS 200 DEDICATED KITS

PRODUCT METHOD TEST

200

ALBUMIN LR BCG BROMOCRESOL GREEN 518

ALKALINE PHOSPHATASE LR DEA DGKC4561152

ALT-GPT LR KINETIC UV OPTIMIZED IFCC 1280AST-GOT LR KINETIC UV OPTIMIZED IFCC 1280AMYLASE LR CNPG3 245BILE ACIDS LR ENZIMATIC 135PANCREATIC AMYLASE LR KINETIC ENZIMATIC 200CALCIUM ARSENAZO LR ARSENAZO III 1309DIRECT FREE CALCIUM LR New! CPC 100CHLORIDE LR MERCURIOUS THIOC YANATE 518CHOLESTEROL LR New! CHOD-PAP 1309DIRECT HDL CHOLESTEROL LR CLEARANCE 580DIRECT LDL CHOLESTEROL LR CLEARANCE 195CHOLINESTERASE LR HEXAC YANOFERRATE III 364CK NAC LR KINETIC OPTIMIZED DGKC-IFCC 338CK MB LR ENZYMATIC 150CREATININE LR JAFFE’ 1036COPPER LR Di Br Paesa 382

DIRECT BILIRUBIN LR JENDRASSIK-GROF MODIFIED5071280

FRUCTOSAMINE LR NBT 456GAMMA GT LR SZASZ 507GAMMA GT LR SZASZ 1280GLUCOSE LR New! GOD-POD 1309IRON LR FERENE 1280LDH LR KINETIC OPTIMIZED SCE 356LACTATE ENZYMATIC LO-POD 105LIPASE LR COLORIMETRICA 190MAGNESIUM LR XYLIDIYL BLUE 518PHOSPHOROUS LR BLUE MOLYBDATE 518POTASSIUM LR TURBIDIMETRIC 570

PRODUCT METHODTEST

200

POTASSIUM LR TURBIDIMETRIC 1400SODIUM ENZYMATIC 150TOTAL BILIRUBIN LR JENDRASSIK-GROF MODIFIED 507TOTAL BILIRUBIN LR JENDRASSIK-GROF MODIFIED 1280TOTAL PROTEIN LR BIURET 1309TRYGLICERIDES LR New! GPO-PAP 1309UREA UV LR KINETIC UV UREASE-GLDH 1309URIC ACID LR URICASE POD-PAP 1309URINARY PROTEINS LR PYROGALLOL RED 516ASO TURBIDIMETRIC 180CRP TURBIDIMETRIC 180RF TURBIDIMETRIC 180CRP UHS New! TURBIDIMETRIC 100IgA TURBIDIMETRIC 150IgG TURBIDIMETRIC 150IgM TURBIDIMETRIC 150IgE New! TURBIDIMETRIC 115C3 TURBIDIMETRIC 150C4 TURBIDIMETRIC 150β2 MICROGLOBULIN TURBIDIMETRIC 180LAMBDA CHAIN New! TURBIDIMETRIC 250KAPPA CHAIN New! TURBIDIMETRIC 250PHENOBARBITAL New! TURBIDIMETRIC 90TRANSFERRIN TURBIDIMETRIC 160LP(a) TURBIDIMETRIC 70MICROALBUMIN TURBIDIMETRIC 160FERRITIN TURBIDIMETRIC 100HbA1c direct New! ENZYMATIC 130HOMOC YSTEINE New! ENZYMATIC 115SISTEMIC SOLUTIONEXTRA WASH CHEM

200 VETERINARY DEDICATED KITS

www.gesanproduction.it

Via Fiera dell’Eremita, 71

91021 Campobello di Mazara - Italy

Phone + 39 0 924 912396

Telefax + 39 0 924 912534

overseas@gesanproduction.it

GESAN in the WORLD !!!

Rev. 03 Ott. 09

Gesan Chem 100Semi-Automatic

Biochemistry Analyzer

Photometric system:

Light source: 6V 10W long-life halogen lamp

Filters: 340,405,492,510,546,578,620nm;±2

nm pass-band

Thermostatic control:

Flow cell temperature: 25, 30, 37 °C, peltier

elements

Precision: ±0.1°C

Measuring system:

Measuring range: 0-3.000 O.D.

Photometric linearity: 0.2A~0.5A±5%,0.5A~

1.0A±4%,1.0A~1.5A±2%

Photometric accuracy: ±1% from 0 to 3.000 O.D.

Reading cuvette:

32ul quartz glass flow through cell

400ul microcuvette

1000ul microcuvette

www.gesanproduction.it Gesan Italy Tel. +39 924 912396 Fax. +39 924 912534

CHEMICAL CHEMISTRY

ALBUMIN LRALKALINE PHOSPHATASE LRALT-GPT LRAST-GOT LRAMYLASE LRCALCIUM ARSENAZO LRCALCIUM CPC LRFREE CALCIUM LRCHLORIDE LRCHOLESTEROL LRCHOLESTEROL MONOREAGENT LRHDL DIRECT CHOLESTEROL LRLDL DIRECT CHOLESTEROL LRCHOLINESTERASE LRDIBUCAINE LRCK NAC LRCREATININE LRCOPPER LRDIRECT BILIRUBIN LRFRUCTOSAMINE LRGAMMA GT LRGLUCOSE LRGLUCOSE MONOREAGENT LRIRON LRT.I.B.CLDH LRLACTATELIPASE LRLITHIUM LRMAGNESIUM LRPHOSPHOROUS LRPOTASSIUM LRSODIUMTOTAL BILIRUBIN LRTOTAL PROTEIN LRTRYGLICERIDES LRTRYGLICERIDES MONOREAGENT LRUREA UV LRURIC ACID LRURIC ACID MONOREAGENT LRBILE ACIDURINARY PROTEINS LRHOMOCYSTEINE LR

TURBIDIMETRIC REAGENTS

ASO TURBILATEXCRP TURBILATEXRF TURBILATEXIGA IGGIGMC3C4α-ACID GLICOPROTEINAPO A1APO BFERRITINTRANSFERRINα-2MACROGLUBULINβ2 MICROGLOBULINα-1 ANTITRYPSINANTITROMBIN IIILP(α)APTOGLOBINFIBRINOGENKAPPA CHAINLAMBA CHAINMICROALBUMINHBA1C DIRECT

ASO LATEX CRP LATEX RF LATEX RPR-CARBONVDRL ANTIGENTPHAWR LATEX WITH CONTROL 100 TESTSIM LATEX WITH CONTROL 50 TESTSSS HCG (SENSIBILITY:300UI/L)

LIQUID DRUGS OF ABUSE REAGENTS

ALCOHOL URINEANPHETAMINE URINEBARBITURATES URINEBENZODIAZEPINES URINECOCAINE METABOLITE URINECOTININE URINEECSTASY (MDMA) URINEMETHADONE URINEMETHADONE METABOLITE (EDDP) URINEOPIATES URINEOXICODONE URINEPCP URINEPROPOXYPHENE URINETHC (CANNABIS) URINE

THERAPEUTIC DRUGS MONITORING

DIGITOXINDIGOXINGENTAMICINPHENOBARBITALPHENYTOINTHEOPHYLLINEVALPROIC ACID

CALIBRATORS AND CONTROLS FOR ALL METHODS

www.gesanproduction.it

CLINICAL CHEMISTRY REAGENTS PRODUCTION

Technical Specifications

Operation features

Power Supply:

Sampling Arm:

Diluter Syringe:

Hydrauuc System:

Wash Station:

Reagents Tray:

Samples Tray:

240 / 100 Vac, 50 / 60 Hrz, single phase with ground On-off switch for Instrument. Independent on-off swltch for refri-gerated reagent plate. Power consumption: less than 200 VA (external PC excluded)

1 sampling needle, 110 mm needle strokeCapacitive liquid level detector Needle shock sensorReagent preheat reel

Long life ceramic plunger Syringe capacity, 500 μl Syringe resolutlon, 0.38 μl

8 self-priming peristaltic pumps (life 1000 hrs) with repla-ceable neoprene cassette (llfe 500 hrs) 2 vacuum pumps, Pinch valve, Manifold Container: Water, 20 l; Cleaning solu-tion, 2 l; Waste, 20 lequipped with level sensor and safety connections

Needles: 6 dispensating, 6 aspiration, 1 clearing (8 step washing sequence for each cuvette)

Refrigerate and removable rack, 30 bottles

(Chem 200 standard) Removable tray, 60 numbered posl-tlons, tubes of 12 -13 mm, 5 - 7 mi / cups of 0.5-1.5 ml(Optional) Removable tray, 20 + 20 numbered positions,20 tubes of 12 -16 mm / 20 cups (Hitachi type)

Cuvette Rotor Reaction Cells:

Optical Group

Photoamplifier:

Control:

External Computer

80 washable BIONEX® cuvettes which allow approximately 20 000 tests for a fully loaded rotor Optic path 6 mm, 220 - 400 ul reactìon volume 100W heating resistance, tempe-rature sensor, safety thermostat

1 halogen lamp (6 V, 10 W) with extended UV emission 2 focusing lenses, optical glass 10-posltion filter disk: 8 po-sitions provided with Interference filters of 340, 405, 505, 546, 578, 600,650, 700 nm wavelengths, 1 free position and 1 solid position for dark reading. Direct reading reaction cuvettes, 6mm optical path ±2 nm on peak wavelength, band pass of ±10 nm

Photoelectric detector, Signal amplifier:Response range, 340 nm to 900 nm Photometric range, O to 3.0 Abs ±0.003 Abs Linearity, ±0.5% full scale Precision: 1 CV% (0.050 to 1.500 Abs) Stability: daily reader offset, less than 1% drift for day

Real-time multitasking microprocessor based control Easy access to the electronics

(Minimum requirements) Intel Pentium IV family with 2 GHz, 20 Gb HD, 512 Mb ram, CD/R 17” monitor, 1280 x 1024 resolution. Keyboard and mouse RS232 standard COM1 serial port Windows® XP pro with ,NET framework 2.0

Sample Diluition :

Temperature Control:

Types Of Tests:

Test Runs:

Measurement Rates:

In-needle dilution if allowed by method’s sample volumes Automatic pre-dilution in a reaction cuvette, up to 1:100

Reagent refrigeration, about -15 °C below room tempera-ture. Reagent preheating reel, O to 100% heat settingReaction cells, heating unit can be set from room tempera-ture up to 42 °C ±0.2 °C (108 °F ±0.5 °F)

Endpoint, Bichromatlc endpoint, Differential endpoint, Differential endpoint sample blank, Fixed Time, Kinetic

Urgent / random

200 tests/hour for mono reagent run Maximum incubation + reading time: single reagent mode, one reading every 20 sec double reagent mode, one reading every 24 sec Typical precision, endpoint 2.5 CV% / kinetic 2.5 CV% Carry-over, lower that 15 parts per million

Start-up:

Calibratton :

Maintenance :

Printing Report:

Needle Washing:

The start-up procedure is run at power-on: self-test,reader offset of optics, wash and check of all cuvettes

Reagent blank subtraction, 1 to 8 standards per test method Linear: factor, linear, linear regression (standard’s repetitions) Non linear (3 interpolation types): cubic-spline, poly-linear and logit-log four parameters. Free standard / control positions on all the sample plate Result can be re-calculated when changing factor or curve

Procedures programmed by component life counters

Single test, complete sample, work sheet, method and QCs Automatic sample reports upon test completion if reque-sted

Sampling needle washed internally and extenaly with Sy-stem solution after every operation

Gesan Chem 300Gesan Chem 300Auto-Chemistry Analyzer

Gesan Chem 300

Stirrer

points

Single100 ml, 70 ml or 20 ml universal reagent bottles

methods.

Gesan Chem 300 clinical analyser

300

300 300

meet the

at

by hand