The Cell: Guide Questions

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    Oncotic Pressure colloid osmotic

    pressure

    osmotic pressureexerted by proteinsthat tends to pullwater into the

    circulatory system attract or pull fluid into

    its compartment

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    Osmotic pressure The hydrostatic

    pressure that will

    prevent movement ofwater from the

    compartment of low

    osmolarity to a

    compartment of highosmolarity.

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    Osmolality

    The total concentration of solute per Kg of the solvent

    Effective Osmolale RC of 1: completely impermeable

    Induces permanent change in volume

    Total Osmole Total number of both the effective and ineffective

    osmole

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    Tonicity

    a measure of the osmotic pressure of two

    solutions separated by a semipermeablemembrane

    influenced only by non-penetrating solutes

    Varying levels of tonicity determine watermovement

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    Differentiate Hypertonic, Isotonic and

    Hypotonic Solutions

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    Hypertonic Solution Cell placed in asolution of NPS

    greater than 300

    mOsm

    Cell Shrinks

    Decrease in cell

    volume The cell has higher

    water concentration

    compared to the

    solution.

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    Isotonic Solution Cell placed in a

    solution of NPS equal

    to 300 mOsm

    Cell Size Remains The cell has the same

    water concentrationcompared to thesolution.

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    Hypotonic Solution Cell placed in a solution

    of NPS less than 300

    mOsm

    Cell Swells

    Increase in cell volume

    The cell has lower water

    concentration compared to

    the solution.

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    Dehydration

    It is a decrease in total bodywater without anequal reduction in total bodysodium.

    Dehydrated patient withborderline blood pressure Drink more water until you reach

    at least a daily consumption ofbetween 10 - 12 glasses

    exercise as much as hydrationbecause exercise may improvevessel tone & increase bloodvolume

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    Dehydration Treatment(Davidsons Principles and Practice of Internal Medicine 19

    th

    Ed.)

    Mild: 0.9% saline 1 litre i.v. 6-12

    hours hourly

    Moderate: 0.9% saline 1 litres i.v. over

    2-4 hours

    Severe: 0.9% saline 2 litres i.v. over

    4-6hours