Chapter 11 Cell Communication. Concept Check Questions Chapter 11 Cell Communication.
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Transcript of Chapter 11 Cell Communication. Concept Check Questions Chapter 11 Cell Communication.
Chapter 11
Cell Communication
Concept Check Questions
Chapter 11
Cell Communication
Explain how nerve cells provide examples of both local and long-distance signaling.
Chapter 11
Cell Communication
Explain how nerve cells provide examples of both local and long-distance signaling.
Synapse = localElectrical = long distance
Chapter 11
Cell Communication
Nerve growth factor (NGF) is a water-soluble signal molecule. Would you expect the receptor for NGF to be intracellular or in the plasma membrane?
Why?
Chapter 11
Cell Communication
Nerve growth factor (NGF) is a water-soluble signal molecule. Would you expect the receptor for NGF to be intracellular or in the plasma membrane?
Why? Hydrophylic
Chapter 11
Cell Communication
What is a protein kinase, and what is its role in a signal transduction pathway?
Chapter 11
Cell Communication
What is a protein kinase, and what is its role in a signal transduction pathway?
A protein that phosphorylates another protein, often in a cascade.
Chapter 11
Cell Communication
When a signal transduction pathway involves a phosphorylation cascade, how does the cell’s response get turned off?
Chapter 11
Cell Communication
Protein kinase = onProtein phosphatase = off
Chapter 11
Cell Communication
Upon activation of phospholipase C by ligand binding to a receptor, what effect does the IP3-gated calcium channel have on Ca2+ concentration in the cytosol?
Chapter 11
Cell Communication
Gate opens.Ca++ flows out of ER.
[Ca++] goes up.
Chapter 11
Cell Communication
How can a target cell’s response to a hormone be amplified more than a millionfold?
Chapter 11
Cell Communication
How can a target cell’s response to a hormone be amplified more than a millionfold?
cascade
Chapter 11
Cell Communication
How can a target cell’s response to a hormone be amplified more than a millionfold?
cascade
Chapter 11
Cell Communication
How can a target cell’s response to a hormone be amplified more than a millionfold?
cascade
Chapter 11
Cell Communication
How can a target cell’s response to a hormone be amplified more than a millionfold?
cascade
Chapter 11
Cell Communication
How can a target cell’s response to a hormone be amplified more than a millionfold?
cascade
Chapter 11
Cell Communication
Explain how two cells with different scaffolding proteins could behave differently in response to the same signaling molecule.
Chapter 11
Cell Communication
Chapter 11
Cell Communication
Chapter 11
Cell Communication
Chapter 11
Cell Communication
Chapter 11
Cell Communication