The Cardiovascular System: The Heart Heart pumps over 1 million gallons per year Over 60,000 miles...
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Transcript of The Cardiovascular System: The Heart Heart pumps over 1 million gallons per year Over 60,000 miles...
The Cardiovascular System: The Heart
• Heart pumps over 1 million gallons per year
• Over 60,000 miles of blood vessels
Functions
• Transport oxygen & carbon dioxide to and from tissues
• Transports nutrients, waste products, and hormones
• Regulates body temperature• Plays a role in the immune response
Important Facts
• A healthy adult heart pumps about 5 liters of blood out per minute.
• During vigorous exercise, the amount of blood pumped out of the heart per minute drastically increases.
• If the heart stops contracting, blood flow throughout the body stops.
• If the heart stops functioning for a few minutes life will end.
Circulation
• Heart is two pumps in one!!!• Pulmonary —right side of heart
forcing blood to flow to the lungs and back to the left side of the heart
• Systemic —left side of heart forces blood to flow to all other tissues in the body and back to the right side of the heart
Circulation
Size, Form, and Location of Heart
• Shaped like a blunt cone
• About the size of a closed fist
• In thoracic cavity between the lungs
• Apex —blunt, rounded point; most inferior part of heart
• Base —larger, flat portion; directed superiorly and slightly posteriorly
Anatomy of the Heart
• Pericardium —double layered, closed sac that surrounds the heart– Pericardial cavity —
space around the heart
• Filled with a thin layer of pericardial fluid—helps reduce friction as the heart moves within the pericardial sac
Layers of Heart Wall
• Epicardium– visceral layer of
serous pericardium
• Myocardium – cardiac muscle
layer is the bulk of the heart
• Endocardium– chamber lining &
valves
Concept Check
• About how big is your heart? What is the inferior portion called? The superior?
• How many miles of blood vessels does your body contain?
• What are the two types of circulation the heart does?
• What are the functions of the circulatory system?
• What are the three layers of the heart?• What surrounds the heart in the body?
Myocardial Thickness and Function
• Thickness of myocardium varies according to the function of the chamber
• Atria are thin walled, deliver blood to adjacent ventricles
• Ventricle walls are much thicker and stronger– right ventricle supplies blood to the lungs (little flow resistance)– left ventricle wall is the thickest to supply systemic circulation
Thickness of Cardiac Walls
Myocardium of left ventricle is much thicker than the right.
External Anatomy of Heart
• Superior/Inferior Vena Cava —carry blood from body to right atrium
• Pulmonary veins —carry blood from lungs to left atrium
• Pulmonary arteries —carry blood from heart to the lungs
• Aorta —carry blood from the heart to the rest of the body
Heart Chambers
• Atria—2 upper chambers– Receives blood from veins– Contraction of atria forces blood into
ventricles • Ventricle—2 lower chambers
– Pump blood out of the heart into arteries– Left is thicker than rightSeptum—separates heart into right and
left sections
Right atrium
Right ventricle
Left atrium
Left ventricle
Septum
SuperiorVena Cava
Aorta
Heart Valves
• Atrioventricular valves—located between atria and ventricles– Prevent blood from
backflow into atrium
• Tricuspid valve—between right atrium & right ventricle
• Bicuspid (mitral) valve—between left atrium & left ventricle
tricuspid
bicuspid
Heart Valves
• Aortic semilunar valve—blood flow from left ventricle to aorta– Prevents backflow
• Pulmonary semilunar valve—blood flow from right ventricle to pulmonary trunk– Prevents backflow
Path of Blood Through Heart
• Enters through Superior/Inferior Vena Cava—Right atrium—tricuspid valve—Right ventricle—pulmonary semilunar valve—pulmonary arteries—lungs—Left atria—bicuspid valve—left ventricle—aortic semilunar valve—aorta
• SA node– cluster of cells in wall of Rt. Atria– begins heart activity that spreads to both atria– excitation spreads to AV node
• AV node– in atrial septum, transmits signal to bundle of
His
• AV bundle of His – the connection between atria and ventricles– divides into bundle branches & purkinje fibers,
large diameter fibers that conduct signals quickly
Conduction System of Heart
Electrocardiogram---ECG or EKG
• EKG– Action potentials of all
active cells can be detected and recorded
• P wave– atrial depolarization
• P to Q interval– conduction time from
atrial to ventricular excitation
• QRS complex – ventricular depolarization
• T wave– ventricular repolarization
Conduction of the Heart
• Fibrillation—heart acting as a lot of pacemakers causing the heart to contract rapidly – Reduces the output of the heart by only a few
milliliters of blood per minute when it occurs in the ventricles—these needs to stop quickly before death sets in
• Defibrillation—a strong electrical shock is applied to the chest region– Trying to cause heart to go back into normal
fibrillation
Auscultation
• Stethoscope• Sounds of heartbeat are from
turbulence in blood flow caused by valve closure– first heart sound (lubb) is created with the
closing of the atrioventricular valves– second heart sound (dupp) is created with
the closing of semilunar valves
Blood Pressure
• Systole—contraction of the ventricles– Atria are relaxed allowing blood to collect– Immediately atrioventricular valves closes– Once pressure builds beyond pressure in aorta
and pulmonary trunk, blood is forced into pulmonary trunk and aorta
• Diastole—relaxation of the ventricles– Atria contract allowing blood to flow into
ventricles– Ventricular pressure decreases– Semilunar valves close
Exercise and the Heart
• Sustained exercise increases oxygen demand in muscles.
• Benefits of aerobic exercise (any activity that works large body muscles for at least 20 minutes, preferably 3-5 times per week) are;– increased cardiac output– increased HDL and decreased triglycerides– improved lung function– decreased blood pressure– weight control.
Congestive Heart Failure • Causes of CHF
– coronary artery disease, hypertension, MI, valve disorders, congenital defects
• Left side heart failure– less effective pump so more blood remains in
ventricle– heart is overstretched & even more blood remains– blood backs up into lungs as pulmonary edema– suffocation & lack of oxygen to the tissues
• Right side failure – fluid builds up in tissues as peripheral edema
Risk Factors for Heart Disease
• Risk factors in heart disease: – high blood cholesterol level– high blood pressure– cigarette smoking– obesity & lack of regular exercise.
• Other factors include:– diabetes mellitus– genetic predisposition– male gender– high blood levels of fibrinogen– left ventricular hypertrophy
Coronary Artery Disease • Heart muscle receiving
insufficient blood supply– narrowing of
vessels---atherosclerosis, artery spasm or clot
– atherosclerosis--smooth muscle & fatty deposits in walls of arteries
• Treatment– drugs, bypass graft,
angioplasty, stent
Clinical Problems• MI = myocardial infarction
– death of area of heart muscle from lack of O2
– replaced with scar tissue– results depend on size & location of damage
• Blood clot– use clot dissolving drugs streptokinase or t-
PA & heparin– balloon angioplasty
• Angina pectoris----heart pain from ischemia of cardiac muscle
By-pass Graft
Stent in an Artery
• Maintains patency of blood vessel
Cardiac Cycle
• Repetitive pumping process that begins with the onset of cardiac muscle contraction and ends with the beginning of the next contraction
• Pressure changes—Blood moves from areas of high pressure to low pressure
• Blood Pressure– Systole– Diastole
Abnormal Heart Sounds
• Called murmurs• Result of faulty valves—valve doesn’t
close tightly allowing blood to enter• Makes a swishing sound immediately
after closure of the valve– Example: incompetent bicuspid valve
makes a swishing sound after first heart sound
Regulation of Heart Function
• Cardiac output— volume of blood pumped by either ventricle of the heart each minute– Cardiac output= stroke volume x heart
rate• Stroke volume— the volume of blood
pumped per ventricle each time the heart contracts
• Heart rate— the number of times the heart contracts each minute