TATIOO: }:;-SoiL( IS

TATIOO: }:;-SoiL( BIRTIIDA TE: IS<;'.;; em SEX:7r��r" SIRE: IV;;"C

DAM: NtrT STUDY: J ..

J.Ji('-0-i<c ,_

CLINICAL SUMMARY

EXPOSURE DATE: AGE AT EXPOSURE: / \ DEATHDATE: 'jt;53 ;; (�C'_) AGE AT DEATH: /7c�

DAYS POST-EXPOSURE:

INHALAnON TOXICOLOGY RESEARCH INSTITUTE GROSS NECROPSY REPORT n ��1! \ol"l

Date "1'133 Ol Time .fa._;__QQ_ Weight 'g. 5 kg.

1'5Sa.u us111 anoo 11

UI>IAHOI IIIOUClt CAICII

Clmic,an BPI M 110?f'" l..vv') Principal Investigator "T \ =f L\\.n.1' ,..-

Stams (circle) H&E

Number of Slides

IOEPATICLN AHTMESS(HTtRICLN

A-R Specials

� Sacdfice'b 0 Euth,�d

;

4 Authod,ed By!:/..£<.,.,4..({��

0 Died- Found By ____ _._ j//<L.._ _____ _

Clinical Diagnosis _ _,\-:,.\uo"-'''-'""""'c;...\""---'d"'-'-' .J.2-'5'\----'50fc"• F.-,e..A

iia<or SAMPlED FOR HISTOPATHOLOGY

WEIGHTS AND MEASUREMENTS

Ht. Wt. _gm LV+S _gm RT.V _gm

AAV_cm LAV __ cm PV __ cm AV __ cm

LVM _em AVM_cm Lung ____ gm

TBLN __ gm Adrenal __ gm Thyroid __ gm

Kidneys __ gm Liver ___ gm Spleen ___ gm

Brain ___ gm Panc. __ X __ X __ em

Other ----------------

PROVISIONAL ANATOMIC DIAGNOSIS

CENTRAL RECORDS

MEDICAL HISTORY OF DOG: 1552U

PROBLEMS

BORN Female Giardiasis

Assigned to MRIC

Otitis externa, bilateral, chronic BAL: RL

BAL: LA, LC, LD, RD, RC, RA

Otitis externa, bilateral, re-occurrence

BAL: LA, LC, LD, RD, RA, RC

Dental calculus, mild

BAL: Trachea, LA,LC,LD,RD,RC,RA

Lymphopenia (900/cumm)

Narrowed IV disc spaces L4-L 7

SACRIFICED

MAB:adm

file: C:\DEAD\1552U.MED

DATE CURRENT DATE

NOTED � RESOLVED

89200

89256

91022

91202

91214

92043

91227

92237

92236

93049

93195

94269

94332

89286

91240

TREATMENTS AND/OR DIETS OF DOG: 1552U

89257 Flagyl, 1/2 Tablet, Oral, Sid for 5 days 90064 Placed on 9 oz. diet 90309 Placed on 12 oz diet 91148 Placed on 9 oz diet 91227 Ears cleaned with EPI-Otic 92142 Ear Examination 92148 Ear examination

/adm WP FILE: c:ll552UI.tre

� ��0.��

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I �

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- INH "TIOIFI bltiCbtUGV RESEARCH INSTITUTE

1S52U 89200 M

RADIATION INDUCED CANCE! -��

(A{21C 'N·O,TF/!::J57VID . 9-Zia·-'i<./ "'y <-"'4

RADIOLOGY

Type of Exam:

·D Chest

0 Abdomen

[2S Survey

0 Extremity

D Othec -----

Anesthesia:

D lnnovar·vet

Rl Atropine I""-\ D Diabutal

D Surital

[1j Holottm!O .1:::-;�<..Y� D Other f'<<;.e C). 2. ....._,

Preparation:--------------------------------

Special Instructions:-----------------------------

Ctin;r.ian'----��::::....e::>..e��"'------- Date_-'-l-"V-1,'/CL/ ________ _

CENTRAL RECORDS

PHYSICAL EXAMINATION (AN)

(Short Form) t4.0. 1 c _):-J. t\ ("'\ \c Tattoo Number \')•-:}.:)_\) (N-Normal) (A-Abnormal)

A. Date '1'1·).'\"( ')It,<\ \r,,l B. Weight�gm

1. Attitude 2. Conformation 3. Hydration

C. Height (Shoulder) __ ._

D. Body Temp. (rectal)\C.O.J£.

4. Nutritional status 5. Superficial lymph nodes 6. Membrane color

E. Pulse Rate (femoral )..J..3...k F. Respiration (rate/min. ).2J.)

7. Skin and ears 8. Eyes 9. Musculoskeletal system

G. General Condition: 10. Respiratory system

1. Comatose 2. Poor 3. Fair

�

11. Cardiovascular system 12. Alimentary system 13. Urinary system 14. Genital system 15. Nervous system 16. Endocrine system 17. Teeth and gums

COMMENTS: ·---------------------- -------- -

---------------------------

Cl i11ician

� ��;;��0�0��:��0� �

� ��;;;i��o�o��o� �

\LATION TOXICOLOGY RESEARCH INSTITUTE

1SS2U 89200 II

RADIATION INDUCED CANCER

-RADIOLOGY

Type of Exam:

), Chest

0 Abdomen

0 Survey

0 Extremity

Anesthesia:

0 lnnovar-vet

�· Atropine \ ""\ 0 Diabutal

0 Surital /VI RIC wo-tt- 1 soc.oos c\0"'-'> ']<!;Jet D Other ----- Pf mtm1mnr :r:.:sv-f/ v """""'---'

'tsQ Other A;< <- 0 · 'd-""' I s/�y Preparation:--------------------------------


l n�ation : --:-:-:-T-----------------------------�o.-_.,-,o 1\J ..J..-

Clinir.ian __ __.,..��;L---- Date tj{t.;f,J

CENTRAL RECORDS

\LATION TOXICOLOGY RESEARCH INSTITUTE ______ .,

lSSZU 89200 K

RAOIATIO� l�OUCfO CANCfR

RAOIOLOGY

Type of Exam:

�Chest

0 Abdomen

D Survey

0 Extremity

L\)() tt= I 3[�� \a D cto"" '1 So'S I Other ___ _

IZ.h�

Anesthesia:

D lnnovar·vet

Jli. Atropine \IN\\ 0 Diabutal

0 Surital

'(1(� -:r::;;-sof\u r"""-"

::¢- Othe< .A (( 0.-;;!_ ""'\ Preparation:--------------------------------


clinki•n•----�-"-'""'....,k�=L-------- Date

CENTRAL RECORDS

•.• rlALATION TOXICOLOGY RESEARCH INSTITUTE

------- _ .:Fk i1 ma-a:- .. ------liorrJfADJO LOGY

" . Type of Exam: Anesthesia:

0 Chest 0 lnnovar-vet

0 Abdomen �Atropine ( """"'( 15S 1U 89200 �

&sucvey 0 Diabutal RADUT!ON

0 O INDUCED CANCER Ext,emity Sudtal

Luo* I �873 0 Dthe, ____ ")& --- :C-mr.\..,� d.o""- q 03 �3':> 1"1. Othe' A C( u. d �J

3/c..�_t}3 Preparation:--------------------------------


Clinir:ian•-----�-'F�""-";..�=:_ _______ _

CENTRAL RECORDS

Date __ 7,_,3"-'Z=._7,_,0::_ _________ _

MEDICAL HISTORY DF DOG: 1552U

PROBLEMS

BORN Female Giardiasis Assigned to MRIC Otitis externa, bilateral, chronic BAL: RL BAL: LA, LC, LD, RD, RC, RA

Otitis externa, bilateral, re-occurrence BAL: LA< LC < LD < RD, RA, RC

Dental calculus, mild

TRC:adm file: C:\ 1552U\.MED

DATE CURRENT DATE

NOTED STATUS RESOlVED

89200

89256

91022

91202

91214

92043

91227

92237

92236

89286

91240

INTEROFFICE MEMORANDUM

TO:

FROM:

Steve Batson/ Animal care

Fredine LaueW

August 9, 1993

SUBJECT: Request for assistance in the drawing of blood from dogs on study 1 FY91-026 (cost code 4071).

On Tuesday, Aug. 10, and Wednesday 1 Aug. 25 dogs on the MRIC study (FY91-026) will be bled by personal in the clinic. They will need a person to restrain the dogs. In the past Diane Bolton has assisted. It would be a great help if a person could assist on the dates above with this duty.


August 10, 1993

TO: Vet. Med.

FROM: F. Lauer�

SUBJECT: Dogs to be bled on Tues .. August 10, 1993.

Below is a list of dogs that will be bled on Tuesday. 40 mls (4 large purple tops) of blood will be drawn from each dog.

Q.illi KENNEL 11 15346 9201 21 15336 J17 31 1552U M02 41 15565 M02 51 15486 M07 61 1524A M07 71 1535T M32 81 1525U M33 91 1526U M33

-- --·- ---

� � � �

� g �

g ! i � ��

� �:��t:� �

� �

� � � <

A.

•• c. D. £. F. &.

'---

I'IIYSICAL EXNIIIIATIOII (All) (Short Fol"ll) 11.0. 1 , 1 L 1 ::J.

Tattao Nllllbll' lc- < �'-(N·Hol"llll) (A-Abnormal)

1! i"" I i"::> Dltt fl '->1"\� 1. Attitude 2. Confol"'llltlon

llelght ) ( • CC 911 3 • Hydration -Height (Shoulder) __ ._

4. Nutritional sutus 5. Superficial l,Y��Ph nodes = lody r_.. (rectal ).Jl..l. • ..,1:. &. Mlmbrane color

Pulse Rite (f..,ral l..J..1L 7. Skin and 11rs 8. Eyes Respiration (rate/•in. )� 9. MusCIIloskeletll syst•

.:ieneral Condition: 10. Respiratory syst• u. Clrdiovascular sysU. 1. CoMtoSI 12. A11...,tlry sysU. 2. Poor 13. Urlnarr syst• 3. Fafr 14. &tftita SysU. 4. liood --=-- 15. Nervous systa. 5. Excllllftt --... u. £ndocri ne sys U. 17. Tilth and.-

C!JIIEIITS:

{ TICMfcfaft

• r

'!HALATION TOXICOLOGY RESEARCH INSTITUTE Jiil"ff"ft�1:;tO£

15 52 u 89200

�[(" OF RADI CT"fR THAN !MM f y <;1· 02 6 4 r' 1

RADIOLOGY

Type of Exam:

0 Chest

0 Abdomen

'0.. survey

0 Extremity

Anesthesia:

0 lnnovar-vet

0 Diabutal

0 Surital

WO:tl- t-z-3/S9. 0 l- '\,:',057 Othe• ----- -g .-.- 1 sJ t"'""""'-"--o-u"'- "'/z.u l '\3

MAl'-' 'SZL Othe• Ace_ 0 • ;;2. ""'-\

Preparation:--------------------------------

Special Instructions: __ \.L"'.!.L. _ _.M=o�"-thcl..!: -'------''5""-'v:c_.r,__,-J.o:...::::J"'---- ------------

� Clinidanl __ ��""-4 :.-,��-:;;:;;. =-------oate __ t.:,f\?<..:'�,P� ---------

cafl1tAL RECORDS

-·-a: "'""&.._,....,.,!,l..:.:i�HAJ,ATION TOXICOLOGY RESEARCH INSTITUTE

R"0NCHOSCOPY REPORT

Anesthesia: Cf'i'-' lnnovar.Vet & Atropine

15 szu 89200 Diabutal

Dosage

/ /

Surital I/

/

MFCH OF RADI CTHFR THA� IMft r., , - oz� � .. J-Lccrcc.,./.. 0 <.(if?'(.:;;,'

Other A� J,r, ·� .n oZ,.,.._(

Procedures

Rigid Bronchoscope

Flexible Bronchoscope

Photographs

Visual Findings

RIGHT LEFT

Diagnosis

Clinician Date

WHITE- CENTRAL RECORDS CANARY CLINICAL PINK PATHOLOGIST

/Route

v /

/ /

� 5G


PROBlEMS

BORN Female

Giardiasis

Assigned to MRIC Otitis externa, bilateral, chronic

BAL: RL

TRC:adm

file: C:\ 1552U\.MED

DATE CURRENT DATE NOTED lli\Il& RESOLVED

89200

89256

91022

91202

91214

89286


89257 Flagyl, 1/2 Tablet, Oral, Sid for 5 days 90064 Placed on 9 oz. diet 90309 Placed on 12 oz diet 91148 Placed on 9 oz diet 91227 Ears cleaned with EPI-Otic 92142 Ear Examination 92148 Ear examination

/adm WP FILE: c:\1552U\.tre

January 27, 1993

TO: Vet. Med.

FROM: F. Lauefip.


SUBJECT: Dogs to be bled on Thurs., January 28, 1993.

Below is a list of dogs that will be bled on Thursday. 40 mls (4 large purple tops) of blood will be drawn from each dog.

DOG KENNEL 1533B K35 1534B K35 1552U L 11 1556S L 11 1524A M07 1548B M07 1535T M32 1525U M33 1526U M33 1545T M46

PHYSICAL EXAMINATION (AN)

{ShortForm) \4.0. I::;L"''S<-!8 Tattoo Number !S5Ql, V (N-Normal) (A-Abnormal)

A. Date 9;;Q.'3Cc 't /03\"1'2..-B. Weight '1]00 gm

c. Height (Shoulder) __ ._

D. Body Temp. (rectal ).JQQ_._Q_ E. Pulse Rate (femoral )..J23_ F. Respiration (rate/min. )___lb. G. General Condition:

1. Comatose 2. Poor 3. Fair 4. Good :-::-----....

. � ent _-J

COMMENTS:

I. Attitude 2. Conformation 3. Hydration 4. Nutritional status

_

5. Superficial lymph nodes _

6. Membrane color 7. Skin and ears B. Eyes 9. Musculoskeletal system

10. Respiratory system 11. Cardiovascular system 12. Alimentary system 13. Urinary system 14. Genital system 15. Nervous system 16. Endocrine system 17. Teeth and gums

Cl irlician


August 18, 1992

TO: Vet. Med.

FROM: F. LauerBP SUBJECT: Dogs to be bled on Thurs., August 20, 1992.

Below is a list of dogs that will be bled on Thursday. 40 mls {4 large purple tops) of blood will be drawn from each dog.

DOG

1526U 15338 15348 1552U 1556S 1524A 15488 1535T 1525U 1545T

KENNEL

9201 K35 K35 Lll

Lll

M07 M07 M32 M33 M46

Diagnosis

Clinician

INHAlATION TOXICOlOGY RESEARCH INSTITUTE

BRONCHOSCOPY REPORT

Anesthesia: 1-<J lnnovar-Vet & Atropine

IS -.�zoo Diabutal

•>CH Of RADI Surital

l=laktthane T�.(u /arr...;;f.L rrurR THAN IMP\ F¥01-026 � e 1 Oth" u �·

LEFT

Date

WHITE- CENTRAL RECORDS CANARY- CLINICAL PINK PATHOLOGIST

Dosage Route

<;<i.-4>1-� I T,\..o-\ •• ,.J so.

� � .

� ! �

�

":::��::: � c_-l

CLINICAL OBSERVATION

Th':::, c\0 w� \.)rc,..JJ'vJ--t-o '\-� '-'\o""'>p;1-ev\ ft>v-

('(_� \i <A.lu �� d ( c:._\r\ .- 0 n I c:..

Q ><--1-e- r" C\.. _ tht_ �r -'S

C-l�.�� O<-V\d odor\e_ss

HOSPITAL ADMISSION a n d DISCHARGE --

1 55 2 u 8 92 00

MfCH OF RADI OTHfR THA� IMM FY<il-026 'c 71

-

Kennel.-!:::fl___ q)J:1.7 81.)-1/

l. 2. 3. 4. 5. 6. 7. 8. 9.

10. 11. 12. 13.

Temp...1JkL..L_Pulse I 0/0Resp�ieight CJ.(d<'f i�: Presenting problem Chrooit Mth"> f.XItmttL y16· History bt!l!kr<A ·

Attitude Confonnation Hydration tlutritional status Super. lymph nodes Membrane co 1 or Skin and ears Eyes flusculoskeletal sys. Respiratory sys.

-

Cardiovascular sys. Alimentary sys. Urinary sys. Genital sys. Nervous sys. Endocrine sys. Teeth and gums

Abnorm.

Comm� : �g� �i}::. ?:(!2'.Ll;nn%:::ti&i£�1i!l;;>,uf:;p�l72ti'f?*

Tentative Diagnosis tJf('th � Date Released_9-'-'-'l <1'--'-� -tl ____ DISCHARGE

Complete physica� �done 4Aaaur ?<d;c> Cl inician._...�Clili_....JL..L..L.=..... _________ _ SUMMARY

' � '1! I

'I r• -� I

Julian Appe

Date tite

f?/;;}, l o.,o.<:l G-qp.;>? 6 'it:t>- 0

: C\. \�>,\ Q

'/)."',)- (..,

lqJl3'>

c -;-;:,-4,

CLINICAL CHAI

,, ) F General Comments:

0> ,:. c. r l A •.

'

Bowels

1\j tJ ,J

tv

/..

; �·M

Urine T p R COMMENTS

('/;,, /, 0 �- I IP?; 11::,\ ')u>-r "'} ..lA.�/,( ..VJ"f IJ\<..; c •. f VJ�,.,r,d / Gf· 'M' i£1 ''"' Nl.l

'" )J,;}, r:n - u:-n>YwV>J 1 ('/,j,;y. �,<"-(' I " ' _,!. '0 '-1-/,, bai• '"' c -;{; ' h.-, -tori a, .()

)'%., li(M_ ·� "'" lf,v )H<.l �'1"""\vo.(',.'-,'-.<, v:fr . .f :,:c.u < 1\c L ii».l ··,; lA.( u.''- LJ.... k(......__

""'- {!-,_ (, . �. ( � j '> ,_w,-, /ht,� :11uX rlnr, ,,n� 1-arcn fn me+ab

f.t.:r t'l hr.,_ ,! n rlrlll Fer exDn< rre. e;h,.,

ul'""' I_, '{-

II rPht'" .-h, -1-f.o hoso;f.o.J rnrvn l:w-rrtYH'' r'r1/d

j, I l1 fi,[,, lc � t! b....t.' IU.d. �(;g .s.J

,l u ) �I .c... .• A + . ,!;. ,.:olu£ r:t..,"r . ' ;,,, .1

ABBREVIATIONS. Appetite. F•fair, G-good, P-poor, 0-none. Bowels: N-normal, D-diarrhea, DB-diarrhea with blood, 0-no feces.

Urine: N-normal, A-abnormal, 0-none.

·-'

ORDER. SHEET

General Comments:

' F " .

' .

Jul 1 an1 Date I ORDER Clinician

h ::>?'l! � _,i_U'k <--ect "C '>/1�.-c'-'-' +! L • 'f.< (QA,__ (t� • .t -n1'� !LJ /'JCJ'7 1 11 k..ztx

!

!

I

I

'

i

i

i r i

I

I

"2-'�XM L::.)t\._ ' 'i ,, __) 1-1 i, l)vl:,

�

-�

'

work Order Issued CoMpleted

- -

�- I

I

I

I I I


BY: Lj/1 �'tA-< l ,,_, ?L-L-ANIMAL ID N•:.___:__:_:> �"---'!f=-----

DATE: 5 f t)/q> Cr�niJ, I I

� clo0� o__ �

�; ��L<__ �+�<, � C}LtfUL

.� � Mlu.� �" k£__

lNHALATION TOXICOLOGY RESEARCH INSTITUTE

BRONCHOSCOPY REPORT

Procedures

155ZU 89200

PHCU Of RADI rTHfR THA� 1"11 fY?1-QZ6 4 r, 71

Rigid Bronchoscope


Photographs

Visual Findings

RIGHT LEFT

Diagnosis

Clinician

j

WHITE CENTRAL RECORDS CANARY CLINICAL PINK PATHOLOGIST

EXPOSURE DATA SHEET- LARGE ANIMAL EXPOSURES

ANIMAL TATTOO #: __ 1_5 _5 _2. _1L:..:.._ __ Venfled by (Initials)'¢ � �

EXPOSURE DATE: ___ _::i'f:..:._Z_I Ic.:"'..:./ __ JULIAN DATE: 7"12.3 '<:.

STUDY DIRECTOR:_J�.F�.�Ldellc�h�n�e�r-------------------

AEROSOL SCIENTIST:�M�.D�-�HllOllO�V�e�r----------------

EXPOSURE SYSTEM OPERATOR: _ _E€Q�8uf..::C��------------

PROTOCOL NO. FY91-026 PROTOCOL TITLE: Mechanisms of

Radiation-Induced Cancer

COST CODE:_�40�7Ll�--- PROJECT TITLE: Mechanisms of Radiation-

Induced Cancer

TOXICANT: ____ 2_3�9P�u�1_6_9Y�b�------------------

METHOD OF EXPOSURE: [INHALATION_X_ INSTILLATION ____ INTRAVENOUS_

OTHER. __________________ _

EXPERIMENT #: 5n''/.ooY

SPECIES: Beagle Dog

ANIMAL#: Oo'J

WEIGHT (kg) : __ cr'-.-'-;>.'-'5""--- SEX:

COMMENTS•---------------------------

xc: Medica 1 Records (Green copy) Mr. E.B. Barr Study Director

1 ); 'U 8?200

rc H OF RAO' I.HR THA'� ffll!'l

F"" , 1-02 6. ' 1

Procedures

Rigid Bronchoscope


Photographs

Visual Findings

RIGHT

Diagnosis

Clinician

INHALATION TOXICOLOGY RESEARCH INSTITUTE BRONCHOSCOPY REPORT

' Anesthesia: 7J;fji) lnnovar-Vet & Atropine

Diabutal

Surital v

Dosage

/

/ /

!

Halothane/0, L"'1%>�;�z

Other Ace�o.-ft1.o..Cl '2-MI

LEFT

Date

WHITE- CENTRAL RECORDS CANARY- CLiNICAL PINK PATHOLOGIST

4 oute

/ /

/

(/1\,a..\ 55(


ANIMAL ID N°.: _ _,_J_· '-r-""- '"-------

DATE: �I

/ ,, I C,. ;:/�;.u /Yt"'<.

/ x"�c JJu 11..£ ;/c 1)

ol/ld I '4. .be{

:;;;;;;;_ 7. I (' ,, n.ucf

")/u, ol-e ,6 . c;/r.l

I 'I C>rU.._.c_ PI'

0 L ' r,.l-)1£

1121 -/{ 1)'1,)

.;, " J, It c-fu...Lc_ h4

' \ fr

,, "" "" c,T- ""r

-C-Yl ""'-

,c /ay !( ��., /1, � ;

PHYSICAl EXAMINATION (AN) (Short Form)

Tattoo Number i ')Sd u

w.o .. _......!.l....:'..!'lcc...i-/:...._ __ _

A. Date 1-11,-q 1 B. Weight I 0000 gm c. Height (Shoulder)

__ .

_

D. Body Temp. (rectal)� • ..:::_ E. Pulse Rate (femoral)� F. Respiration (rate/min.)� G. General Condition:

1. Comatose 2. Poor 3. Folr 4. Good �. Excellent

COMMENTS:

_]__fJ_

<+:· kl

J I

Technician

(N-Nonnal) (A-Abnormal)

1. 2. 3. 4. 5. 6. 7. a. 9.

10. II. 12. 13. 14. 15. 16. 17.

Attitude Conformation Hydration Nutritional status Superficial lymph nodes-Membrane color �

··skin and ears Eyes Musculoskeletal system Respiratory system Cardiovascular system Alimentary system Urinary system Genital system Nervous system Endocrine system Teeth and gums

CJL,.::,·� , 1-,1:� r-:r � ..... _ Arfk4� e

f

Cllolclan

7

J:•AGt;: PR01DCDL FY91-026

MECHANISMS OF RADIATI•)N INDUCED CANCER

ASSIGNED AS •)F •;'11.:01:. 1Ju! v .:.r:;, 1 ·� ·:, 1)

T ATTOI) VM!:.THDTE SE�< \IM_CSTC D ·.;M_ TITLE

1''541 T :::·�;' 14"5 F 41)71 RP.DIATII)N INDUCED CfiNCER

1':·4.:L: :::·:•/ 1 '34 M 41)71 G:AQIATION INDUC ED CANCEr.:

l':.A..:S :::·�I/ 1'54 F 4(1{ 1 F.;lDIATI(tN INDUCED ':.ANCER

1'544.l :: �. '!5':1 M 4(•71 RADIATION HJOU(ED C AN(Ef".:

1�-141:: ::·:,, 1':··=1 M 4071 RADIATION INDUCED c A�J.: :s·

��44S :.;:·='.:1':··:, F ·�(·7! F:<\0 � ·:oT ii)N fNDUCEJ •:MKfF:

1'544T :::·:.OJ15':;;, F 4071 RADIAT!(IN INGUCEO ·: Ar�CEF-·

1'544U :39/ 1'5:, F 4(171 RADIATION INDUCED CANCEF\

1545T ::;·;·; 11!.:3 F 4071 RADIATION INDUCED •:-AN(ER

1546A ::.:·=·; 1·::.5 M 4071 RADIATION INDUCED C AN(ER

154.:,.(: :39/165 M 41)71 RADIATION INDUCED CANCER

15463 ::;·;1/ 1·.:.5 F 4071 RADIATION INDUCED C.ANC::::R

1546T :;:·=1/ ltE.? F -1.(171 RADIATION tNDUCED C�NCER

1 547A :;:·:;;,; lr.:.::> M 4071 RADIATION I NDUCED C ANCER

1547S :3'?/ 1�.::: F 4071 RADIATION INDUCED CANCER

1547T ::;:'?; 168 F 4071 RADIATION INDUCED CAf.JCER

1547U :3';'1/168 F 4071 RAOIATit)N INDUCED CANCER

1548A :39/t:::.:. M 4071 RADIATION INDUCED CANCER

15488 :39/18.:: M 4071 RADIATION INDUCED CANCER

154::.:c ::.:·?/ t:::: M 41)71 RADIATION INDUCED CAN(.ER

1!5485 89/1:32; F 4071 RADIATION INDUCED CANCER

1�48T a·:;.;1sz: F 4071 RADIATION INDUCED CANCER

1548V $9/182 F 4071 RADIATION INDUCED CANCER

1550E 8'�/ 1'?1 M 4071 RADIATION INDUCED CANC ER 1!551C :39/1'?6 M 4071 RADIATION INDUCED CANCER

1551S 89/196 F 4071 RADIATION INDUCED CANCER

1 '551 T :39/1'?6 F 4071 RADIATION INDUCED CANC ER

1!5!52:A 891:200 M 4071 RADIATION INDUCED CANCER

15529 :3;9/200 M 4071 RADIATION INDUCED CANCER

15!525 :s·:;>;zoo F 4071 RADIATION INDUCED CANCER

1552T 8'?/200 F 4071 RADIATION INDUCED CANCER

15!52U 8'?/200 F 4071 RADIATION INDUCED CANCER

155:3A 89/2()6 M 4071 RADIATION INDUCED CANCER

1�'53S 89/206 F 4071 RAD IATION INDUCED CANCER

1!5!5?A 89"342 M 4071 RADIATION INDUCED CANCER

1556S 89/342 F 4071 RAD I ATION INDUCED CANCER

15!57S 89/3'53 F 4071 RADIATION INDUCED CANCER

PROBLEMS

BORN Female

Giardiasis

file: C:\1552U\.MED


DATE CURRENT DATE NOTED � RESOLVED

89200

89256 89286


89257 Flagyl, 1/2 Tablet, Oral, Sid for 5 days 90064 Placed on 9 oz. diet 90309 Placed on 12 oz diet 91148 Placed on 9 oz diet

/adm WP FILE: c:\1552UI.tre

A.

8.

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PHYSICAl EXAMINATION (AN) (Short form) w.o .. _�O"'-<]'-'s::!""-"§...,.(e'-7...._

Tattoo Number I 'S 5,2 L) (N-Nonna 1) (A-Abnormal )

Date '10,.-;{Me a:/2..3/qo Weight j OQQO 9"'

Height (Shoulder) __ ._

Body Temp. (rectal ).ili!J.._L Pulse Rate (femoral)� Respiration (rate/min.)� General Condition:

1. Comatose 2. Poor 3. Fair

� �

1. 2. 3. 4. s. 6. 7. 8. 9.

10. 11. 12. 13. 14. 15. 16. 17 0

Attitude Conformation Hydration _ Nutritional status

_ Superficial lymph nodes _

Membrane co 1 or ··skin and ears

Eyes Musculoskeletal system Respiratory system Cardiovascular system Alimentary system Urinary system Genital system Nervous system Endocrine system Teeth and gums

COMMENTS :

Clinician

· - -.-------

. --�-:-----

NEW MEXICO DEPARTMENT OF AGRICULTURE

VETERINARY DIAGNOSTIC SERVICES 700 Camino de Salud NE Albuquerque. New Mexico 87106 Phone (505) 841·2576

Page: 2

9002061 1541T 9002062 15428 9002063 1542S 9002064 1542T

9002065 1543S 9002066 1544A 9002067 15448 9002068 1544S 9002069 1544T

9002070 1544U 9002071 1545T 9002072 1546A 9002073 15468 9002074 1546C 9002075 1546D 9002076 1546E 9002077 1546F 9002078 1546G 9002079 1546S 9002080 1546T 9002081 1547A 9002082 1547S 9002083 1547T 9002084 1547U 9002085 1548A 9002086 15488 9002087 1548C 9002088 1548S 9002089 1548T 9002090 1548V 9002091 15508 9002092 1550T 9002093 1551C 9002094 I 55 IS 9002095 1551T 9002096 1552A 90020'17 15528 9002098 1552S 9002099 1552T 9002100 1552U 9002101 1553A 9002102 1553B 9002103 1553S 9002104 1553T

1:640

I :160 1:160

1:160 1:40 I :80 I :80 I :20 I :20 1:40 I :40 I :1280 I :80 I :40 I :640 I :1280 I :640

1:160 I :80

I :160 I :40 I :320 I :40

I :80 I :40 I :40 I :40 1:640 I :80

I :640 I :640

1:320 I :1280

I :640 I :320 I :40 I :1280 1:640 I :160 I :80 1:160

1:80 1:80 1:160

Case: 90-02025 Species: Canine

Owner: Lovelace P090005110006 Animal Name:

INHALATION TOXICOLOGY RESEARCH INSTITUTE URINE/FECAL REPORT

HISTORY (Reason for submission)

REQUESTED BY OATE SUBMITTEO /Cl)/,5/o<J

0URINALYSIS COLLECTION METHOD

Compression ___________ _

Cathete rization __________ __

Cage _____________ _

Other _____________ _

CHEMISTRY (chemstrip-8) Sugar ____________ _;m;;,;g/..::dl Albumin ___________ _:me::: g= /dl

OMICROSCOPIC COMMENTS DIRECT'

Hemoglobin ERY/ug CYTOCENTRIFUGE Acetone ____________ _

Bilirubin ____________ _

Urobilinogen __________ _cmc:glc:;dl

Occult blood __________ ER_Y-'-/u--" g

Nitrite Sp. Gr -------------pH ________________________ _

Color _____________ _

Turbidity ____________ _

TECH/PATH

MICROSCOPIC �Parasites

Date

DTrypsin OOther WBC _______________________ __ Procedure Used __ ____________ _

ABC ________________________ __ Results Casts

Hyaline ____________ _

Granular ____________ _

WBC or ABC ___________ _

Other _____________ _

Bacteria ____________ _

Renal Cells -------------Crystals ____________ __

(}1() p():A_a.-uLu �

TECH/PATH---..L./;AlfJ'-"---� , • NTRAL RECORDS


Jjo;;J-U HISTORY (Reason for submission)

REQUESTED BY

0 URINALYSIS COLLECTION METHOD

Compression ___________ _

Catheterization __________ __

Cage _____________ _

Other _____________ _

CHEMISTRY (chemstrip·B) Sugar ____________ .::mC!:gjce. d l

Albumin, ___________ _:::m]!gj;::d l

DATE SUBMITTED

OMICROSCOPIC COMMENTS DIRECT

Hemoglobin ERY/ug CYTOCENTAIFUGE

Acetone ____________ _

Bilirubin ____________ _

Urobilinogen __________ .::m::.!g::::i d l

Occult blood ________ _

---=.ER�Y:c_/� ug

Nitrite ------------

Sp Gr -------------

pH _______________________ _

Color _____________ _

Turbidity ____________ _

MICROSCOPIC

TECH/PATH

J:tl'Parasites

Date

0Trypsin OOther WBC ___________________ _____ __ Procedure Used ______________ _

ABC ________________________ _ ReStJits Casts:

Hyaline ____________ _

Granular ____________ _

WBC or RBC. ___________ _

Other ____________ _

Bacteria ____________ __

Renal Cells ___________ _

Crystals ---------------

TECH/PATH __ ___.C£2""'"''----- Date �he.,JR2

--'L RAL RfCORDS


/rf'&J-U HISTORY (Reason for submission)

REQUESTED BY

0 URINALYSIS COLLECTION METHOD

Compression•------------

Catheterization __________ _

Cage _____________ _

Other _____________ _

CHEMISTRY (chemstrip·8) Sugar ____________ _:_m2g/:_:: d l Albumin•------------"''""'-"g/dl

DATE SUBMITTED

OMICRDSCOPIC COMMENTS DIRECT

fr.erx-krf

Po s;d

Ca11i5

Hemoglobin EAY/ug CYTOCENTAIFUGE Acetone ____________ _

Bilirubin ____________ _

Urobilinogen __________ _:_m:;,gc::;/ dl Occult blood _________ _:_ER_:_Y_:_ i�u g

Nitrite ------------

Sp Gr -------------pH ____________ _

Color _____________ _

Turbidity ____________ _

MICROSCOPIC

TECH/PATH

��sC

¢�EOUESTED parasites

JYI�/-rot7tdt{ <ol.t:!_

(;, "- Gr � rcL<a

r-eksf /Cre<..l

Date

0Trypsin OOther WBC ___________ _ Procedure Used ______________ _ ABC _ _ _ _ _ _ _ _ _ _ _ _ _

Casts Hyaline'-------------

Granular ____________ _

WBC or ABC ___________ _

Other ____________ _

Bacteria ____________ _

Renal Cells ___________ _

Crystals-------------

C.E'IITRAL RFCORDS

Results

& �cb � �� 'V.s-15 tf-

� TECH/PATH ___ __:C():.>..'---- Da • e" --:.�q.f..t.,t {..t.f;);,:.L.f_ .__ rt

.·

OBSERVATION

ev: t55i! S E :Wne s ANIMAL Ill: /55) 1._/tft'r Date: 'i';qJS !e clfl3 /s'J

/SS::l'A/

ISSJ t3 v

155�5-!55oJT/ /S':>JU.

77Jese pu..pfHw -!esl-eci ;:;os ihVe. fOr

#!0 will k (Jiatf'd

on tnd-ron;dcoole SO,m:J )K� X 5 cl. 7he;r

-k{'al Nil/ k re/es-kcl of '-fk t'mX

o+ </he Ire a fmM-1-.

/ j{/(}· P CeClJle.. piau <fAuu._ � pu<J on ; / z. fcJ;Ie._ +-

/'f)e_-fron,da-zole Cr:to;;'jl) Pa sicl x.Sd fhe/11 !'€ -ks-1 k ccd Scuv,fJ Le__

UOEROFnCEMEMO�UM January 22, !991

TO: Dr. F. F. Hahn

FROM: Dr. B. A Muggenburg �

SUBJECI': Mechanisms of Radiation Induced Cancer: Assignment of Dogs for Studies Other than Immunology

The dogs listed in the attached tables are available for this study for exposure

after January I, 1991. We have assigned equal numbers of males (59) and females (59).

These dogs were born from May, 1987 to September, 1991. This allows for an exposure

window beginning now until October, 1991. Ten extra dogs were assigned to allow for

the exclusion of dogs that receive too much or too little plutonium aerosol.

BAM:pls WI Attachments

XC: Dr. C H. Hobbs Dr. D. G. Thomassen Dr. B. B. Boecker Dr. N. F. Johnson Dr. K. J. Nikula Dr. D. G. Burt

TABLE 1

Mechanism of Radiation Induced Cancers: Assignment of Dogs for Studies Other Than Immunology

[emal�attoo Birthdat� Female!J'attoo Blrthdate

1498 u 87180 1525 s 88348

1501 T 87227 1529 T 88023

1502 s 87228 1537 T 89123

1508T 88043 1541 T 89145

1509 s 88062 1542 s 89154

1509T 88062 1545 T 89163

1509 u 88062 1546 s 89165

1511 s 88088 1546 T 89165

1511 u 88088 1547 s 89168

1512 s 88111 1547 T 89168

1512 u 88111 1547 u 89168

1514 T 88133 1548 s 89182

1514 v 88133 1548 T 89182

1515 T 88141 1548 v 89182

1515 u 88141 1550T 89191

1515 v 88141 1551 s 89196

1516T 88146 1551 T 89196

1516 u 88146 1552 s 89200

1517 u 88160 1552 T 89200

1521 s 88279 1552 u 89200

1521 T 88279 1553 s 89206

1521 u 88279 1553 T 89206

1522 s 88323 1553 u 89206

1522 v 88323 1556 s 89342

1522 w 88323 1557 s 89353

1523 s 88330 1560 s 90055

1523 T 88330 1560T 90055

1523 u 88330 1565 s 90163

1523 v 88330 1567 s 90270

1524 s 88340

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