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    Marie Azeneth A. Josol, RPh

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    The metric system is the internationally

    accepted system of weights and measures and

    is the official system of the United States

    Pharmacopeia (USP) and National Formulary

    (NF).

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    The base units (the primary units of

    measurement) of the metric system are gram

    for weight, liter for volume, and meter for

    length. In this system, prefixes are used to show

    which portion of the base unit is being

    considered. It is important that you learn the

    most commonly used prefixes.

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    SI METRIC SYSTEM

    UNIT ABBREVIATION EQUIVALENTS

    WEIGHT gram (base unit) g 1 g = 1000 mgmilligram mg 1 mg = 1000 mcg = 0.001 gmicrogram mcg (or g) 1mcg = 0.001 mg = 0.000001gkilogram kg 1 kg = 1000 g

    VOLUME liter ( base unit ) L ( or ) 1 L = 1000 mlmilliliter mL ( or m ) 1 ml = 1cc = 0.001 Lcubic centimeter cc 1 cc = 1 ml = 0.001 L

    LENGTH meter ( base unit ) m 1 m = 100 cm = 1000 mmcentimeter cm 1 cm = 0.01 m = 10 mmmillimeter mm 1mm = 0.001 m = 0.1 cm

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    EXAMPLE 1 :

    Convert: 0.3 g to mg Equivalent: 1 g = 1000 mg. Conversion

    factor is 1000

    THINK: Larger to smaller: (x)

    Multiply by 1000 0.3 x 1000 = 300 mg

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    EXAMPLE 2 :

    Convert 5000 mL to L Equivalent: 1L = 1000 mL. Conversion

    factor is 1000

    THINK: Smaller to larger : ()

    Divide by 1000 5000 () 1000 = 5L

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    common systems ofmeasurement include the

    apothecaries system and the

    avoirdupois system.

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    The apothecaries system is the traditional

    and historic system of weights and measures

    used in pharmacy.

    system is expressed by unique units and

    symbols, namely the minims (m ), grain (gr.),scruple (), drachm or dram (), ounce (0z),

    pound (lb.).

    The avoirdupois system uses the three unitsof weight, the grain (gr), ounce (oz), and

    pound (lb.).

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    Conversion Equivalents of Length

    1 meter (m) = 39.37 in

    1 inch (in) = 2.54 cm

    Conversion Equivalents of Volume1 fluidounce (f3) = 29.57 mL = 30 mL

    1 pint (pt) = 473 mL

    1 gallon (US) = 3785 mL

    1 gallon (US) = 128 f3Conversion Equivalents of Weight

    1 gram (g) = 15.432 gr

    1 kilogram (Kg) = 2.2 lb

    1 grain (gr) = 0.065 g or 65 mg1 oz ( 437.5 gr ) = 28.35 g

    1 lb ( 7,000 gr ) = 454 g

    Common Household Equivalents

    1 teaspoon ( tsp or t ) = 5 mL

    1 tablespoon ( tbsp or T ) = 15 mL

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    The apothecary system was the first

    system of medication measurement used

    by pharmacists and physicians.

    The grain (gr) has the same value of

    weight in both the apothecaries andavoirdupois systems.

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    Convert each of the following:

    6.35 mm to inches

    2.5 L to fluidounces

    12.5 g to grains 6.5 grains to milligrams

    2 pt. to milliliters

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    A nurse telephones a pharmacy regarding

    the proper quantity of an injection to

    administer to a pediatric patient from a 1

    ml vial contaiing 0.1mg of digoxin. The

    attending physician had prescribed a doseof 25mcg. How many ml should be the

    pharmacists response?

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    A hospital pharmacist is asked to prepare an

    intravenous infusion of dopamine. Based on the

    patients weight the pharmacist calculate a doseof 500mcg/min. for continuous infusion. The

    concentration of the infusion is 400mcg/250ml.

    What is the concentration of the infusion on

    mcg/ml basis? How many ml of dopamine is thepatient to receive in the first hour treatment?

    How long will infusion last?

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    Case 1:

    0.1mg/ml= 100mcg/ml

    35 mcg X 1ml/100mcg=1/4ml or 2.5ml

    Case 2:

    Conc. Of infusion, mcg/ml

    400mg= 400,000mcg

    400mg:250ml =400,000mcg/250ml=1600mcg/ml

    Mg, dopamine 1st hour

    500mcg/1min X 60 min/Hr X1mg/1000mcg

    = 30mg/hour

    Infusion duration

    400mg X 1min/500mcg X1000mcg/1mg = 800min or 13hour and 20 mins.

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    e.g :Convert 140F to C:

    5F = 9C + 160 (formula)

    5(140) = 9C + 160

    700 = 9C + 160700 - 160 = 9C

    540 = 9C

    60 = C