Swine vesiculardisease
-
Upload
mahmoud-ghonim -
Category
Education
-
view
331 -
download
1
Transcript of Swine vesiculardisease
![Page 1: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/1.jpg)
Swine Vesicular Disease
Porcine Enterovirus Infection
![Page 2: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/2.jpg)
Center for Food Security and Public Health Iowa State University - 2004
OverviewOverview
• Organism• Economic Impact• Epidemiology• Transmission• Clinical Signs• Diagnosis and Treatment• Prevention and Control • Actions to take
![Page 3: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/3.jpg)
The Organism
![Page 4: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/4.jpg)
Center for Food Security and Public Health Iowa State University - 2004
Swine Vesicular DiseaseSwine Vesicular Disease
• Virus−Family Picornaviridae
Genus Enterovirus• Related to human enterovirus• Unrelated to other porcine enteroviruses
−Survives for long periods in environment and in meat products
−Resistant to Temperatures up to 157 oF pH ranging from 2.5-12
![Page 5: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/5.jpg)
Importance
![Page 6: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/6.jpg)
Center for Food Security and Public Health Iowa State University - 2004
HistoryHistory
• 1966: First identified in Italy−Confirmed in
Hong Kong Japan Western Europe
• Eradication successful in most countries
• Outbreaks−1990s: Italy, Spain, Portugal
![Page 7: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/7.jpg)
Center for Food Security and Public Health Iowa State University - 2004
Economic ImpactEconomic Impact
• Does not cause severe production losses
• Major economic importance−Difficult to distinguish from foot-and-
mouth disease−Control measures, eradication costly−Trade restrictions
![Page 8: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/8.jpg)
Epidemiology
![Page 9: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/9.jpg)
Center for Food Security and Public Health Iowa State University - 2004
Geographic DistributionGeographic Distribution
• Has occurred in− Italy, Hong Kong, England, Wales, Japan,
Germany, Poland, Switzerland, Greece and Spain
• Has not occurred in North America or Australia
• Eradicated from most countries• As of 2003, only found in Italy and
Portugal
![Page 10: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/10.jpg)
Center for Food Security and Public Health Iowa State University - 2004
Morbidity/MortalityMorbidity/Mortality
• Moderately contagious• Compared to foot-and-mouth
−Lower morbidity, less severe lesions• Mortality not generally a concern
−Low in adult pigs−Up to 10% in piglets
• No persistent infection• Protective antibody developed
![Page 11: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/11.jpg)
Transmission
![Page 12: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/12.jpg)
Center for Food Security and Public Health Iowa State University - 2004
Animal TransmissionAnimal Transmission
• Contact − Infected animals or feces
• Ingestion − Contaminated meat scraps
• Excretion of virus− Nose, mouth, feces− Up to 48 hrs. before clinical signs seen− Shed in feces for >3 months after infection
![Page 13: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/13.jpg)
Center for Food Security and Public Health Iowa State University - 2004
Human TransmissionHuman Transmission
• Laboratory workers−Contact with SVD pigs or SVDV−Variety of illnesses developed
Traceable to SVDV infection Seroconversion Mild clinical disease One case of meningitis
![Page 14: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/14.jpg)
Animals and Swine Vesicular Disease
![Page 15: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/15.jpg)
Center for Food Security and Public Health Iowa State University - 2004
Clinical SignsClinical Signs
• Incubation period: 2-7 days• Very similar to foot-and-mouth disease• Vesicles and erosions
− Snout, mammary glands, coronary band, interdigital areas
• Neurological signs rare• Abortion not typically seen• Recovery within 2-3 weeks
− Little permanent damage
![Page 16: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/16.jpg)
Center for Food Security and Public Health Iowa State University - 2004
Foot & Mouth Disease
Vesicular Stomatitis
Swine Vesicular Disease
Vesicular Exanthema of
Swine
Clinical Signs by Species
All vesicular diseases produce a fever with vesicles that progress to erosions in the mouth, nares, muzzle, teats, and feet
Cattle
Oral & hoof lesions, salivation, drooling, lameness, abortions,
death in young animals, "panters";
Disease Indicators
Vesicles in oral cavity, mammary glands, coronary
bands, interdigital space
Not affected Not affected
Pigs
Severe hoof lesions, hoof sloughing, snout vesicles, less severe
oral lesions: Amplifying Hosts
Same as cattle
Severe signs in animals housed on
concrete; lameness, salivation,
neurological signs, younger more
severe
Deeper lesions with granulation tissue
formation on the feet
Sheep & Goats
Mild signs if any; Maintenance Hosts
Rarely show signs Not affected Not affected
Horses, Donkeys,
Mules Not affected
Most severe with oral and coronary
band vesicles, drooling, rub
mouths on objects, lameness
Not affected Not affected
![Page 17: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/17.jpg)
Center for Food Security and Public Health Iowa State University - 2004
Clinical SignsClinical Signs
• Vesicles−Feet−Snout−Tongue−Teat
![Page 18: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/18.jpg)
Center for Food Security and Public Health Iowa State University - 2004
Clinical Comparisons: Snouts Clinical Comparisons: Snouts
• Swine Vesicular Disease
• Vesicular Stomatitis
• Foot and Mouth Disease
• Vesicular Exanthema
![Page 19: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/19.jpg)
Center for Food Security and Public Health Iowa State University - 2004
Clinical Comparisons: FeetClinical Comparisons: Feet
•Swine Vesicular Disease
•Foot-and-mouth
•Vesicular Exanthema
Photos: www.aphis.usda.gov
![Page 20: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/20.jpg)
Center for Food Security and Public Health Iowa State University - 2004
Post Mortem LesionsPost Mortem Lesions
• Vesicles are the only post mortem lesions
![Page 21: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/21.jpg)
Center for Food Security and Public Health Iowa State University - 2004
Differential DiagnosisDifferential Diagnosis
• Foot-and-mouth disease• Vesicular stomatitis• Vesicular exanthema of swine• Chemical or thermal burns
![Page 22: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/22.jpg)
Center for Food Security and Public Health Iowa State University - 2004
SamplingSampling
• Before collecting or sending any samples, the proper authorities should be contacted
• Samples should only be sent under secure conditions and to authorized laboratories to prevent the spread of the disease
![Page 23: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/23.jpg)
Center for Food Security and Public Health Iowa State University - 2004
DiagnosisDiagnosis
• Clinical−Vesicles and erosions on mouth and feet
• Laboratory testing−Essential to rule out other vesicular
diseases• Available tests
−ELISA, direct complement fixation−Virus isolation−Serology: Virus neutralization, ELISA
![Page 24: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/24.jpg)
SVD in Humans
![Page 25: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/25.jpg)
Center for Food Security and Public Health Iowa State University - 2004
SVD in HumansSVD in Humans
• Incubation period: 1-2 weeks• Clinical signs
−Mild influenza-like symptoms−Generalized abdominal and muscle pain−Aseptic meningitis (one case)−No vesicular lesions
• Diagnosis: seroconversion• Treatment: supportive care
![Page 26: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/26.jpg)
Prevention and Control
![Page 27: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/27.jpg)
Center for Food Security and Public Health Iowa State University - 2004
Recommended ActionsRecommended Actions
• Notification of Authorities−Federal:
Area Veterinarian in Charge (AVIC) www.aphis.usda.gov/vs/area_offices.htm
−State veterinarian www.aphis.usda.gov/vs/sregs/official.htm
• Quarantine
![Page 28: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/28.jpg)
Center for Food Security and Public Health Iowa State University - 2004
ControlControl
• Slaughter− Infected pigs−Pigs in contact with SVD pigs−Disposal
• Disinfection−1% sodium hydroxide + detergent−Oxidizing agents− Iodophors + detergent
![Page 29: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/29.jpg)
Center for Food Security and Public Health Iowa State University - 2004
VaccinationVaccination
• Never been done• Inactivated vaccines
−Not commercially available
• We all need to do our part−Keep our pigs healthy and
free of disease
![Page 30: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/30.jpg)
Center for Food Security and Public Health Iowa State University - 2004
Additional ResourcesAdditional Resources
• World Organization for Animal Health (OIE)− www.oie.int
• USAHA FAD – “The Gray Book”− www.vet.uga.edu/vpp/gray_book
• Food and Agriculture Organization of the United Nations− www.fao.org
• USDA-APHIS website− www.aphis.usda.gov
![Page 31: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/31.jpg)
Acknowledgments
Development of this presentation was funded by a grant from the Centers for Disease Control and Prevention to the Center for Food Security and Public Health at Iowa State University.
![Page 32: Swine vesiculardisease](https://reader035.fdocuments.in/reader035/viewer/2022062406/558a6569d8b42a5f4a8b45e0/html5/thumbnails/32.jpg)
Author:
Co-authors:
Reviewer:
Jean Marie Gladon, BS
Kristina Rovid Spickler, DVM, PhDKristina August, DVMJames Roth, DVM, PhD
Bindy Comito Sornsin, BA
Acknowledgments