Suresh Query

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Drug Information Center RVS/SVCOP Query on: 17.08.2015 Chittoor 517127 A.P Answered on: 17.08.2015 Query: Treatment of streptococcal induced endocarditis?. Query from : Hari mam Name: 12GT1T0025 Phone/e-mail:[email protected] Thank you for asking a query. Please ask more queries on the same or other topics. Answering may take 3 working days. Dept. of Pharmacy Practice, RVS Hospital, RVS Nagar, Chittoor (dt) E-mail: Phone:. Disclaimer: This is a confidential message, please discard or return it if you are not the intended recipient. It is highly advisable to refer other standard drug information resources for more complete or specific answers.

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Transcript of Suresh Query

Page 1: Suresh Query

Drug Information Center RVS/SVCOP Query on: 17.08.2015 Chittoor 517127 A.P Answered on: 17.08.2015

Query: Treatment of streptococcal induced endocarditis?.

Query from : Hari mam Name: 12GT1T0025 Phone/e-mail:[email protected]

Thank you for asking a query. Please ask more queries on the same or other topics. Answering may take 3 working days.

Answer:

Treatment of Endocarditis Caused by Penicillin-Sensitive Streptococci: The penicillins, often in combination with gentamicin, remain the cornerstones of therapy for endocarditis caused by penicillin-susceptible streptococci. For penicillin-allergic patients, vancomycin is substituted. IV ceftriaxone, given once daily for 4 weeks, is another option, and even a 2-week course in combination with gentamicin. 

ANTIBIOTIC,DOSAGE REGIMEN,DURATION (Weeks)Penicillin G,12-18 MU IV q24h,4Ceftriaxone,2g IV q24h,4Ceftriaxone plus gentamicin,2g IV q24h,1mg/kg IV q8h,2Vancomycin,1g IV q12h,4

Treatment of Endocarditis Caused by Penicillin-Insensitive Streptococci: penicillin-insensitive streptococci, the penicillin dosage is higher and duration of therapy is 2 weeks. Gentamicin is given for the first 2 weeks; both penicillin and gentamicin are given for 6 weeks. Patients who are penicillin-allergic, should receive vancomycin.

ANTIBIOTIC,DOSAGE REGIMEN,DURATION (Weeks)Penicillin G or ceftriaxone plus gentamicin,4 MU IV q4h,4-6,2g IV q24h,4-6,1mg/kg IV/IM,q8h,2Vancomycin,1g IV q12h,4-6

ANSWERED BY: SURESH.T REFERENCE: www.clevelandclinicmeded.com

Dept. of Pharmacy Practice, RVS Hospital, RVS Nagar, Chittoor (dt) E-mail: Phone:. Disclaimer: This is a confidential message, please discard or return it if you are not the intended recipient. It is highly advisable to refer other standard drug information resources for more complete or specific answers.

Page 2: Suresh Query

Drug Information Center RVS/SVCOP Query on: 17.08.2015 Chittoor 517127 A.P Answered on: 17.08.2015

Dept. of Pharmacy Practice, RVS Hospital, RVS Nagar, Chittoor (dt) E-mail: Phone:. Disclaimer: This is a confidential message, please discard or return it if you are not the intended recipient. It is highly advisable to refer other standard drug information resources for more complete or specific answers.