Supporting Information for Synthesis, Molecular …Sowjanya Polepalli,b Gundla Rambabuc...
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1 Supporting Information for Synthesis, Molecular Docking and in vitro Antiproliferative activity of Novel Pyrano[3,2- c]carbazole derivatives Pannala Padmaja,* a Basireddy V. Subba Reddy, b Nishant Jain, b Srinivasa Rao Mutheneni, b Priyanka Bollepelli, b Sowjanya Polepalli, b Gundla Rambabu c Pedavenkatagari Narayana Reddy* c Table of content 1. Copies of 1 H and 13 C NMR spectra of products 2-16 Electronic Supplementary Material (ESI) for New Journal of Chemistry. This journal is © The Royal Society of Chemistry and the Centre National de la Recherche Scientifique 2016
Transcript of Supporting Information for Synthesis, Molecular …Sowjanya Polepalli,b Gundla Rambabuc...
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Supporting Information for
Synthesis, Molecular Docking and in vitro Antiproliferative activity of Novel Pyrano[3,2-
c]carbazole derivatives
Pannala Padmaja,*a Basireddy V. Subba Reddy,b Nishant Jain,b Srinivasa Rao Mutheneni,b Priyanka Bollepelli,b
Sowjanya Polepalli,b Gundla Rambabuc Pedavenkatagari Narayana Reddy*c
Table of content
1. Copies of 1H and
13C NMR spectra of products 2-16
Electronic Supplementary Material (ESI) for New Journal of Chemistry.This journal is © The Royal Society of Chemistry and the Centre National de la Recherche Scientifique 2016
2
3
13C NMR of 11a in CDCl3
0.00.00.50.51.01.01.51.52.02.02.52.53.03.03.53.54.04.04.54.55.05.05.55.56.06.06.56.57.07.07.57.58.08.0
1H NMR of 11a in DMSO
N
O O
O
OO
4
13C NMR of 11b in CDCl3
0.00.00.50.51.01.01.51.52.02.02.52.53.03.03.53.54.04.04.54.55.05.05.55.56.06.06.56.57.07.07.57.58.08.08.58.5
1H NMR of 11b in DMSO
N
O O
O
OO
5
0.00.00.50.51.01.01.51.52.02.02.52.53.03.03.53.54.04.04.54.55.05.05.55.56.06.06.56.57.07.07.57.58.08.08.58.5
1H NMR of 11d in CDCl3
N
O O
NH
NH
O O
OO
00101020203030404050506060707080809090100100110110120120130130140140150150160160
N
O O
NH
NH
O
OO
O
13C NMR of 11d in CDCl3
6
0.00.00.50.51.01.01.51.52.02.02.52.53.03.03.53.54.04.04.54.55.05.05.55.56.06.06.56.57.07.07.57.58.08.08.58.5
1H NMR of 11e in CDCl3
N
O O
NN H
OO
00101020203030404050506060707080809090100100110110120120130130140140150150160160
13C NMR of 11e in CDCl3
N
O O
OO
N
NH
7
0.00.00.50.51.01.01.51.52.02.02.52.53.03.03.53.54.04.04.54.55.05.05.55.56.06.06.56.57.07.07.57.58.08.08.58.59.09.0
1H NMR of 11f in CDCl3
N
O O
NN
OO
-10-1000101020203030404050506060707080809090100100110110120120130130140140150150160160
13C NMR of 11f in CDCl3
N
O O
OO
N
N
8
00112233445566778899
1H NMR of 11g in CDCl3
N
O O
NN
Cl
OO
00101020203030404050506060707080809090100100110110120120130130140140150150160160
13C NMR of 11g in CDCl3
N
O O
OO
N
N
Cl
9
-0.5-0.50.00.00.50.51.01.01.51.52.02.02.52.53.03.03.53.54.04.04.54.55.05.05.55.56.06.06.56.57.07.07.57.58.08.08.58.5
1H NMR of 11h in CDCl3
N
O O
NN Cl
OO
00101020203030404050506060707080809090100100110110120120130130140140150150160160
13C NMR of 11h in CDCl3
N
O O
OO
N
N Cl
10
0.00.00.50.51.01.01.51.52.02.02.52.53.03.03.53.54.04.04.54.55.05.05.55.56.06.06.56.57.07.07.57.58.08.08.58.5
1H NMR of 11i in CDCl3
N
O O
NN CN
OO
00101020203030404050506060707080809090100100110110120120130130140140150150160160
13C NMR of 11i in CDCl3
N
O O
OO
N
N CN
11
0.00.00.50.51.01.01.51.52.02.02.52.53.03.03.53.54.04.04.54.55.05.05.55.56.06.06.56.57.07.07.57.58.08.0
1H NMR of 11j in CDCl3
N
O O
NN Br
OO
00101020203030404050506060707080809090100100110110120120130130140140150150
13C NMR of 11j in CDCl3
N
O O
OO
N
N Br
12
001122334455667788991010
1H NMR of 12a in CDCl3
N
O O
OH
00252550507575100100125125150150175175200200
N
O O
OH
13C NMR of 12a in CDCl3+ DMSO
13
0011223344556677889910101111
1H NMR of 12b in DMSO
N
O O
OH
00252550507575100100125125150150175175200200
13C NMR of 12b in DMSO
NH
O O
O
14
0011223344556677889910101111
1H NMR of 12f in DMSO
N
O O
H
NN
00101020203030404050506060707080809090100100110110120120130130140140150150160160
13C NMR of 12f in DMSO
NH
O O
N
N
15
0011223344556677889910101111
1H NMR of 12i in DMSO
N
O O
H
NN CN
00101020203030404050506060707080809090100100110110120120130130140140150150160160170170
13C NMR of 12i in DMSO
NH
O O
N
N CN
16
00112233445566778899101011111212
1H NMR of 12j in DMSO
N
O O
H
NN Br
00101020203030404050506060707080809090100100110110120120130130140140150150
13C NMR of 12j in DMSO
NH
O O
N
N Br
