Suggestions For Peri-Procedural Management Of Edoxaban

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Suggestions For Peri-Procedural Management Of Edoxaban Published on Anticoagulation Services (https://depts.washington.edu/anticoag/home) Suggestions For Peri-Procedural Management Of Edoxaban . CrCl T 1/2 Time of last dose of edoxaban prior to procedure (peri-procedural bridging is generally not required) Standard Risk of Bleeding High Risk of Bleeding 1 (major surgery, spinal puncture or placement of spinal/epidural catheter, and other situations in which complete hemostasis is required 1 ASRA 4th edition 2018: hold 72 hours for all patients prior to neuraxial procedures, without regard for influence of renal function on half-life and clearance 80-95 ml/min 10-14 hrs at least 24 hours at least 48 hours 50-79 ml/min 10-14 hrs 30-49 ml/min 10-14 hrs 15-29 ml/min 17 hrs at least 48 hours at least 72 hours < 15 ml/min unknown edoxaban assay is currently unavailable at UWMedicine to determine absence of drug effect Source URL (modified on 06/28/2018 - 15:38): https://depts.washington.edu/anticoag/home/co ntent/suggestions-peri-procedural-management-edoxaban ©2014 University of Washington Page 1 of 1

Transcript of Suggestions For Peri-Procedural Management Of Edoxaban

Suggestions For Peri-Procedural Management Of EdoxabanPublished on Anticoagulation Services(https://depts.washington.edu/anticoag/home)

Suggestions For Peri-Procedural Management Of Edoxaban .CrCl T 1/2 Time of last dose of edoxaban prior to

procedure

(peri-procedural bridging is generally notrequired)

Standard Risk ofBleeding

High Risk ofBleeding1

(major surgery, spinal puncture or placement of spinal/epiduralcatheter, and other situations in which complete hemostasis is

required

1ASRA 4th edition 2018: hold 72 hours for all patients prior toneuraxial procedures, without regard for influence of renal function

on half-life and clearance

80-95 ml/min 10-14 hrs at least 24 hours at least 48 hours50-79 ml/min 10-14 hrs30-49 ml/min 10-14 hrs 15-29 ml/min 17 hrs at least 48 hours at least 72 hours< 15 ml/min unknown edoxaban assay is currently unavailable at

UWMedicine to determine absence of drug effect

Source URL (modified on 06/28/2018 - 15:38): https://depts.washington.edu/anticoag/home/content/suggestions-peri-procedural-management-edoxaban

©2014 University of WashingtonPage 1 of 1