© CAMAG 2018

SUCCESS STORY CAMAG – INNOSUISSE (CTI)Markus Wyss, Ph.D.

CEO, CAMAG

CAMAG – 60 years dedicated to chromatography

CAMAG was founded 1958 in Muttenz, Switzerland

Niche business: Production of Aluminum Oxide for chromatography

World-market leader: Instruments and software for High-Performance Thin-Layer

Chromatography (HPTLC), an analytical method

Launched: Automated high-throughput elution instrument (DBS-MS 500) to analyze dried

blood spots in clinical diagnostics

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CAMAG – Global Presence

CAMAG Muttenz (Headquarters): provides

direct sales & services within Switzerland

and to countries having no appointed

distributor

Two subsidiaries:

CAMAG Berlin for Germany, The Netherlands,

Belgium & Austria

CAMAG Scientific Inc. for North America

More than 70 distributors serving more than 90

countries worldwide

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TLC in all its versions

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Instrumental TLC

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Application

Detection

Documentation

Development

The Plate

Comparison of multiple Samples: Curcuma

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0.1 g/mL methanol, ultrasonication for 10 min; centrifugation; toluene - acetic acid (4:1)

Limit-Test for THC-free Cannabis samples

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A breakout for CAMAG: Dried Blood Spot Analysis

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INNOSUISSE (CTI) Projects with CAMAG

2010: DBS-MS direct blood spot analysis system for Mass Spectrometer

Prof. Dr. Agathe Koller-Hodac

2012: DMS/DBS-MS: Extension of the capabilities to suit the hospital market for therapeutic

drug monitoring Prof. Dr. Agathe Koller-Hodac

& PD Dr. Manuel Haschke

2014: Automated extraction of dired blood for the newborn screening

Prof. Dr. Götz Schlotterbeck

PD Dr. Ralph Fingerhut

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Institut für Labortechnologie

Hochschule für Life Sciences

Institut für Labortechnologie

DBS-MS 500 Dried Blood Spot Analysis for Diagnostics

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Robotics

Optical card

recognition

Software

Extraction

Internal

standard

application

Blood spotting

Cleaning

DBS-LC-MS/MS System used for Newborn-Screening, Forensic and Therapeutic Drug Monitoring

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Automated High-Performance Thin-Layer Chromatography (HPTLC) for Routine Analysis

HPTLC format and layer (20 x 10 cm, 200 µm layer thickness)

Proper instruments for all steps (including software)

Standardized methodology

Validated methods

results in

Reproducible results

plate to plate, day to day, lab to lab …

cGMP compliance

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New Instruments in Development

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INNOSUISSE (CTI) Projects with CAMAG on HPTLC

2014: Next generation High-Performance Thin-Layer Chromatography (HPTLC)

Prof. Dr. Agathe Koller- Hodac

2017: Next generation High-Performance Thin-Layer Chromatography: Integration of

additional functionality in specific modules to complete the Next Generation concept.

Prof. Dr. Agathe Koller- Hodac

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Institut für Labortechnologie

Institut für Labortechnologie

Benefit for the Research Partners to apply for a INNOSUISSE (CTI) Project

Applied research - to be commercialized immediately

Generation of IP rights (outside the field of interest of the industrial partner)

Education of the next generation of scientists

Access to commercially relevant research topics

….but not optimal for basic research projects

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Benefit for Industry Partner to apply for a INNOSUISSE (CTI) Project

Reduce time to market

Be able to choose from cutting-edge technology - without permanent employment

Generate IP in the field of interest – competitive advantage

Focused on Switzerland, all handled within the Swiss administration

Mentor to help file the request - experts to challenge it

Optimal for SME’s

….but industrial partner has to be ready to invest into the future (> 50% own investment)

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© CAMAG 2018

Additional Information: www.camag.com

or during the follow-up in our discussion group tonight