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  1. 1. STrengthening the Reporting of OBservational studies in Epidemiology - Nutritional Epidemiology STROBE-nut An extension of the STROBE statement The STROBE-nut consortium Lachat et al. (2016) PLoS Med. ;13(6):e1002036
  2. 2. In this presentation What are research reporting guidelines and why do they matter How to use research reporting guidelines correctly What is STROBE What is STROBE-nut: a STROBE extension for nutritional epidemiology Where to find more information
  3. 3. Why better reporting matters Poor reporting is a major source of research waste Published trial reports: 4089% were non-replicable1 Most studies had at least one primary outcome changed, introduced, or omitted from the protocol1 Research papers are incomplete Authors may not know what essential information to include Reviewers/editors may not know what should be included Consequence Incorrect interpretation of findings Loss of studies and information 1 Glasziou et al. 2014.. The Lancet, 383, 267-276
  4. 4. EQUATOR: Research reports should present sufficient information to allow a full evaluation of the presented data and further use of these findings Reporting guidelines: lessons for journal editors from the EQUATOR Network Presentation Altman EQUATOR 2014
  5. 5. What are reporting guidelines? Tools for authors, reviewers and editors to ensure completeness and transparency of manuscripts Contain items to be reported Organized mainly As a checklist, explicit text, a flow diagram or a combination Following the structure of a research paper (Introduction, Methods, Results, Discussion and Conclusion) Examples: CONSORT, PRISMA, SPIRIT 2Turner et al. 2012. Systematic Reviews, 1. evidence shows that use of reporting guidelines influenced reporting quality of reporting of randomized controlled trials2
  6. 6. What are reporting guidelines Not A straitjacket for research papers Restrictions in writing style, creativity or clarity of papers Instructions that interfere with the editorial or review process Quality appraisal tools for studies
  7. 7. STROBE-statement STROBE: STrengthening the Reporting of OBservational studies Evidence-based, minimum set of recommendations for reporting of observational studies. A set of 22 items to report cohort studies, case-control studies and cross-sectional studies. STROBE-extensions STROBE-extensions: provide guidance for specific areas e.g. STREGA: Genetic Associations STOBE-ME: Molecular Epidemiology STROME-ID: Infectious Diseases
  8. 8. Nutritional epidemiology Assess the diet-disease relationship in humans Nutritional epidemiology is one of the younger disciplines in epidemiology Indications that reporting is problematic E.g. 13 of the 17 literature reviews for the 5th revision of the Nordic Nutrition Recommendations report a lack of methodological details causing lower quality rating or exclusion of papers.3 3Nordic Council of Ministers (2014)
  9. 9. STROBE-nut An extension of the STROBE- statement for nutritional epidemiology and dietary assessment Checklist of 24 recommendations Use checklist together with STROBE-nut paper STROBE- nut explanation and elaboration document (under preparation) Other STROBE extensions e.g. STROBE-ME The STROBE explanation & elaboration document
  10. 10. Method Start 2014 Collaboration between 4 research groups Input from 3 Delphi rounds with 53 external experts Consensus through 3 face-to-face meetings
  11. 11. Get involved Reporting guidelines rely on their usefulness for users Continuous & interactive process to improve recommendations Submit feedback, comments, and new evidence on the STROBE nut website or [email protected]
  12. 12. Resources Equator network : Research waste Downloads Updates and translations.. User comments