©2016 HGST, Inc. All rights reserved.

Storage Solutions for Healthcare and Life SciencesDavid Hiatt, Market Development - Healthcare and Life Sciences

August 23, 2016

9/6/2016 2

Long Live Data™

HGST and WD are independent subsidiaries of Western Digital Corporation

Sandisk is now integrated into both subsidiaries

Rich Heritage

Powerful Platform

Company Formation

©2015 HGST, Inc. All rights reserved. Confidential

9/6/2016

Long Live Data™

3

Executing on Our Strategic PrioritiesRecent Acquisitions

Expanding our capabilities and investing for ongoing growth

9/6/2016

Long Live Data™

4©2016 HGST, Inc. All rights reserved.

SOFTWARE

ClusteringManagement

Storage Analytics

STORAGEACTIVE ARCHIVE

Data AnalyticsBackup and ArchiveCloud Infrastructure

CAPACITY SCALE HDD

Backup – Object Storage

CAPACITY HDD

Cloud Storage – Hyperscale

SAS SSD

Online Transactions – HPC

PERFORMANCE HDD

Processing – Content Serving

NVMe

Databases &Analytics

Data Center Product Portfolio

HGST innovates at every level

of the storage stack – from the

fastest solid-state drives to the

densest storage systems

available.

9/6/2016

Long Live Data™

5

Our Connection to Life Sciences

©2015 HGST, Inc. All rights reserved. Confidential

Private testing centers– Partnering with large biopharmas

– 23 and Me / Pfizer depression study

New business models– Data brokers

Precision medicine– Enabled by digital pathology and genomic

sequencing

– Connecting systems for single view of patient

Interest in Digital Pathology accelerating– Europe leads United States

– Companies looking to go all digital

Partly cloudy outlook– Cloud providers partnering with med tech

Age of informatics - analytics platforms– Delivering insights from vast quantities of data

– Indica Labs, Inspirata, Proscia

Data is being shared and retained longer– Larger images and more complex image analysis

– Elixir, National Data Services

9/6/2016

Long Live Data™

6

HGST in Your Lab

©2015 HGST, Inc. All rights reserved. Confidential

Local workstations– Sequencers & Microscopes

– Flash, HDD & SSD

– Value: faster data/image capture and transfer

Processing server cluster– PCIe SSD for data acceleration

– Infiniflash for primary storage and buffering

– Value: analytics and acceleration, allows use of less specialized servers

Active Archive System & JBODS– Consolidate tier-2 and backup into single

shared archive

– Value: collaboration, cloud scalability, greater data durability

9/6/2016 7

Long Live Data™

©2015 HGST, Inc. All rights reserved.

Traditional storage solutions don’t fit data at scale

DIY storage is inefficient

Cloud storage costs are not predictable

Compliance and security concerns

Getting data to the cloud

More Data, More Challenges

9/6/2016 8

Long Live Data™

AWS Public CloudPrivate Cloud w/Bursting

Leverages the Power and Scale of Object Storage

9/6/2016 9

Long Live Data™

What Does 1 Petabyte Look Like? InfiniFlash System™

Ultra-dense High Capacity Flash storage– Up to 512TB in 3U, Scale-out software for PB scale capacity

Highly scalable performance–Industry leading IOPS/TB

Robust storage services –Automatic rebalancing

–Hot Software upgrade

–Snapshots, replication, thin provisioning

–Fully hot swappable, redundant

Integrated with a broad array of SDS platforms–Spectrum Scale, Red Hat, OpenStack + Ceph, Nexenta

9/6/2016

Long Live Data™

©2016 HGST, Inc. All rights reserved.

Built upon the software technology heritage of

Active Archive OS 4.1.1

• Rateless Erasure Code• 3 geo dispersion • Encryption – DARE• Usability improvements• BitDynamics®

• BitSpread™

Complete scale-up and scale-out object storage system

©2015 HGST, Inc. All rights reserved.

672TB-4.7PB raw capacity

Unbreakable Durability

Breakthrough TCO

Linear Scale Performance

Simplified Management

What Does 5 Petabytes Look Like? Active Archive System™

©2016 HGST, Inc. All rights reserved.

Thank You

Please Join Us Later for the Reception

9/6/2016 12

Long Live Data™

Value Comparison

Private CloudPublic Cloud

Pros– Single point of contact

One throat to choke

– Entirely Opex

– Operational expertise

– Broad developer support

– Dynamic compute scalability

– Ease of application deployment

Cons– Longitudinal data TCO -

– Significant egress costs

– Security and compliance concerns

Proof of secure erase and data locality

Pros– More cost effective than AWS

Longitudinal data TCO - $$$$$$$$$

Glacier cost structure w/std. cloud performance

– Local support and resources (SDSC)

– Primary customer; specialized experts directly involved

– Data locality and security

– AWS-like storage availability w/o replication

– Allows geo-dispersion among research partners (TACC, etc.)

– No ingress/ egress costs

Cons– Multiple partners

– Small developer community

– Ease of application deployment ???

9/6/2016

Long Live Data™

13

Challenges with Traditional Storage Architectures

©2015 HGST, Inc. All rights reserved. Confidential

Complex architecture with multiple tiers of expensive specialized storage

Limited scalability

Costly storage software licensing

Higher system management costs

Expense of onsite and offsite tape storage for disaster recovery

Overhead of tape media management

No protection from data degradation means no guarantee archives will be readable

9/6/2016

Long Live Data™

14

Customer Pain Points

©2015 HGST, Inc. All rights reserved. Confidential

Costly infrastructure does not scale (NAS and/or tape), hindering research

Infrastructure does not support global collaboration and shared file access

Complex infrastructure with data silos and diverse software apps

Unexpected storage requirements

Machines in constant use, more data is generated

What’s creating new opportunity?

Faster, cheaper instruments mean more scenarios investigated more data kept longer

New tools and analytics mean new insights from old data increasing data value

Technology advancements have downstream effects lens change = 2-5x more data per image

9/6/2016

Long Live Data™

Life Sciences Use Cases

Active Archive

Genomics

Bioimaging

Journal Archives

©2016 HGST, Inc. All rights reserved.

9/6/2016

Long Live Data™

16

Life Sciences Workflows

©2015 HGST, Inc. All rights reserved. Confidential

Genomics– Genome sequenced and raw data is generated,

highly compressible text data

– Multiple passes made to generate desired quality/accuracy

– Genome is reconstructed/aligned from data during processing phase

– Variants to reference genome identified and recorded

– Output: structured data file of variants

Bioimaging– Image data captured from slides (little

compression)

– Image processing and distortion correction

– Analyze image to measure size, composition, etc.

– Output: image composites and measurement data

– 3D and cryo-electron microscopes mean giga- and tera-pixel images

Similar but different