Steroidogenic pathways for the major steroid hormones. All steroid hormones are produced through a series of enzymatic reactions that modify cholesterol molecules, such as by varying the side groups attached to them. Each steroidogenic organ can produce only those steroid hormones for which it has a complete set of the enzymes needed to appropriately modify cholesterol, after fi rst converting it to pregneneolone. The active hormones produced in the steroidogenic pathways are highlighted by screens. The intermediates that arenot biologically active in humans are not screened. The adrenal cortex has the enzymes necessary to convert cholesterol into the mineralocorticoid aldosterone, the glucocorticoid cortisol, and the weak androgen dehydroepiandrosterone. The testes can synthesize the potent androgen testosterone. The ovaries produce various estrogens and progesterone.

Gangguan fungsi adrenokorteks

Gangguan fungsi adrenokorteks