SPF-290S Analyzer System

Optometrics Corporation

• MeetsNEWFDAUVAin-vitrotestprocedure• SupportsrevisedBootsprotocol• NowwithNEWValidationKit• NEWWinSPFsoftwarev4.0• Windows®AutomationandMeasurementSoftware

SettingthestandardforIn-VitroSPFassaysof:

LotionsCreamsCosmeticsFabrics

SPF-290S Analyzer System

Optometrics CorporationADynasilCompany

LASER COMPONENTS (UK) LtdGoldlay House, 114 Parkway, Chelmsford, Essex. CM2 7PR, Phone: 01245 491 499, Fax: 01245 491 801, [email protected]

Products• Gratings Originals and Replicated, Ruled and Holographic;

Grazing Incidence, Echelles, Telecom and Transmission Gratings

• Beamsplitters Reflecting/Transmitting

Beamsplitters, Transmission Grating Beamsplitters, Beam Dividers/Combiners

• Optical Components Mirrors, Lenses, Windows, Flats, Beamsplitters,

Prisms

• Filters HardandSoftCoated,NearUltraviolet,

Visible,NearInfrared,LaserLineFilters

• Infrared & Laser Products Laser Gratings,

Holographic and Ruled Wire Grid Polarizers

• Monochromators Mini-Chrom

Monochromators

• Systems & Accessories Monochromatic Light Modules, Sample

Compartments,Detectors,LightSources,ModularRecording Spectrophotometers

• SPF-290S Spectrophotometer for determining Sunscreen

Protection Factors

Plus specialized packaging, bar coding and Kanbanstocking arrangements for all OEM customers.

OptometricsCorporationwouldliketothankyouformakingtheSPF-290Stheinstrumentofchoicefor

in-vitro evaluation of the sunscreen protection factors of various formulations and raw materials. This recording UV spectrophotometer is designed and optimized forthe determination of SPF values, Boots Star Ratings and AustralianTNUVstandards,amongstothers,onavarietyofsunscreen,cosmeticproductsandfabrics.

With an installed base of over 300 unitsworldwide,Optometrics has set the standard for SPF measurement foralmost20years.TheSPF-290Scanprovidereliableresultsonthemostdifficultsamples.Aneasy-to-usein-vitro testingmethodology combinedwith reproducibleresults,usingauser-friendlysoftware interface,opensthedoor toefficientand lowcostexperimentaldesigntechniques for formulation optimization. This will result in faster formulation and lower development costs due to a reductionintheneedforexpensiveandtimeconsumingin-vivo panel studies.

FacilitiesOptometrics’facilityinAyer,Massachusettscontainsspaceforoffices,engineering,R&Dandproduction.Equipmentthatsupportourbroadrangeofcapabilitiesincludes:• Fourmetalvacuumcoatingsystems;• Threethin-filmsoftcoatedfiltervacuum coatingsystems;• TwoIon-AssistedDepositionhardcoatvacuum coatingsystems;• Threegratingrulingengines;• Productionholographiclaboratory;• R&Dholographiclaboratory;• Fullreplicationandlaminationfacilities;• Fullassembly,alignmentandtestfacilities;• Fullcomplementoftestequipmentforspectraltesting fromtheUVtotheFarInfrared,formechanicaland flatnesstesting,forhumidityandenvironmentaltesting;• Extensivemarking,packagingandbarcoding equipmentandcapabilities

Optometrics Corporation



TABLE OF CONTENTSSPF-290S Analyzer SystemMeasurement.....................................................5

DataAcquisition&Analysis ........................... 6-7

Automation ........................................................8

Specifications ....................................................9

TurnkeySystems .............................................10

List .......................................................... 11

GoalsOptometrics goal is to provide advanced optical com-ponents and systems for use inwavelength selectionapplications in:• AnalyticalChemistry• LifeSciences• TelecomApplications• Physics• Education• SpaceSciences andotherapplicationswherehighqualityopticsarekey.

Inordertoaccomplishthis,theCompanyhasassembledstate-of-the-art facilities and people to produce:• diffractiongratings:ruled&holographic,original&

replicated,reflectionandtransmission• interferencefilters• opticalcomponents• lasergratings&products• monochromators&accessories• spectrophotometers• wiregridpolarizers:ruled&holographic

OEM ServicesOptometrics caters, in particular, to the needs of its OEMcustomersbyofferingspecialservicessuchas:• Kanbanstockingarrangements• Custompackagingprograms• Barcodingcapabilities• Codenamesforcompleteconfidentiality• Higherlevelpre-alignedopticalassemblies

Thecompanyisalsoproudofitsabilitytosupportcustom-ersinallphasesoftheproductdevelopmentcycle.



NOW AVAILABLE• MeetsNEWFDA/UVAin-vitro test procedure• NowwithNEWValidationKit• NEWsoftwarev4.0•Windows® automation and measurement software• SupportsrevisedBootsprotocol

OVER 300 CUSTOMERS WORLDWIDEAvon,BASF,Clairol,ElizabethArden,EsteeLauder,GoodHousekeeping, ISP, Johnson& Johnson, LeverBros,L’Oreal,MaryKay,Merck,Revlon,Rohm&Haas,Proctor&Gamble,Unilever,Andrew Jergens,HeleneCurtis,Whitehall Robins, Bayer, S/C/Johnson, Bristol-MyersSquibb,TanningResearch,Pfizer,Boots(theChemist)andAmway…tonamejustafew!

Setting the standard for in-vitroSPFassaysof:

• Lotions• Creams• Cosmetics• Fabrics



MEASUREMENTTheSPF-290S is a recordingUV spectrophotometerdesigned and optimized for the determination of SPF valuesonavarietyofsunscreenandcosmeticproductsreducingtheneed(andcost!)forin-vivotesting.

Covering both the UVB and UVA spectral regions,the systemautomatically scans from290 to 400 nm,accumulating and storing data at intervals of 1, 2 or5nm.Themonochromatic protection factor (MPF) isdetermined for each of the selected wavelengths and is used to calculate the SPF value, using solar irradiance anderythemalconstantsthatareprogrammedintothesoftwarebutwhichcanbeeasilymodified.

Ultra-violet(UVB)andnearultra-violet(UVA)radiationis

providedbya125WCWXenonarc lamp.

A horizontal sample areapermits testing of liquids,

creams,emulsionsandsprays.

An integrating sphereplacedjustbelowthe

sample collects light scattered bytheproductandits

supportingsubstrate,increasingmeasurementaccuracy.

SPF-290S SAMPLE HANDLING & SUPPORT MEDIALiquids,creamsandgelsareappliedinsmall“dabs”or“spots”totheTransporeTape®orothersubstrate,withthepipettesuppliedwiththesystem.Thesubstrateisplacedonanopenmetal frame.Thesample is spread lightlyandevenlyovera50cm2areaat2µl/cm2, equivalent to in-vivo testing.

QuartzplatesareavailablefromOptometricsforspraysandotherdifficultsamples.

DESIGNED TO MEETTHE NEEDS

OF SPF ASSAYS

Measurement


SPF-290S Analyzer System DataAcquisition&Analysis

SOFTWARE FEATURES• CalculateandprintSPFvalues• Bothtabularandgraphicalformats• BootsStarRatingscalculated• Createformulationassaysofupto36scans• DisplayMPFandabsorbancevalues• Photo-stabilitytesting• Calculateareaunderthecurve• Criticalwavelengthcalculation• UVA/UVBratio• Completeon-linehelpmenu• Viewscansindividually• CalculatesTNUVstandard• SupportsFDAUVAin-vitro test procedure

AND NEW WITH WinSPF v4.0• Abilitytousewavelengthintervalsof1,2or5nm, supporting revised Boots protocol• Supportforupto12referencescanstoeliminate variations in reference measurements• TaylorapproximationforcalculatingMPFstandard deviations with multiple reference scans• Optionalsolarsimulatorspectra• Factorsoutdarkcurrent• TrapezoidalorSimpson’sruleapproximationsfor integral calculations• Newcomprehensivetestfeatureforusewith ValidationKit

FullyFunctionalToolbar

CompleteOn-Line

HelpSystemSystemTest

and Validation

Single StepControlIcons

UtilizesAllWindows Features:

Printing, ScreenCapture,Etc.

Switch BetweenDisplayFormats

Data can be acquired in approximately 20 seconds. Results displayed in easy to read format.


SPF-290S Analyzer SystemDataAcquisition&Analysis

CORRELATION BETWEEN SPF-290S AND IN-VIVO SPF TESTINGThe high correlation between the SPF-290S’s in-vitromeasurements and in-vivo test results gives youconfidencethattheinstrumentwillbeareliableguidetoproduct performance.

The chart shows data comparisons for a variety ofcommerciallyavailableproductsincluding:

• physicalsunscreens• sprays• waterproofsunscreensandstickformulations

TheSPF-290Scanprovidereliableresultsonthemostdifficultsamples.

An easy-to-use testingmethodology combinedwithreproducibleresultsopensthedoortoefficientandlowcost experimental design techniques for formulationoptimization. This will result in faster formulation and lower development cost due to a reduction in the need forextensivein-vivopanelstudies.


SPF-290S Analyzer System Automation

COMPUTER CONTROLLED SAMPLING STAGEThere are two modes of computer controlled operation:

• programmedreadingofupto12locations (Autoscan),and,• timebasedmeasurements(photo-stability)

Autoscanmodeofferstwomethodsofchoosingupto12samplinglocations.Theoperatorcaneitherspecifythepositionstobereadorthecomputercangeneratethemrandomly.Onceset, theoperation,datacollectionandreportingareperformedautomatically.Thestagemovesthesampleontheholderintothelightbeam,takesthemeasurements,movestothenextpositionandcontinuesuntilallthemeasurementshavebeencompleted.

Time-based(photo-stability)measurementsmonitortheSPF values for a sample at a user specified positionagainsttime.Theeffectsofdryingandexposuretoairandlightonasamplecanbeeasilyevaluated,makingitparticularlysuitableforphotostabilitytesting.Thesystem’scomputerprovidesacontrolledrepeatabletimebaseformeasurements.

Computationofstatisticsformultipleassaysisprovidedbythesoftware.

X-Y SAMPLING STAGETheComputerControlledX-YSamplingStage:

• Reducestheoverallcostoftesting,• Freestechniciansforothertasks,• Improvestherepeatabilityandaccuracyof measurements, and• Facilitatesphoto-stabilitytesting

CumulativeAbsorbance

or SPF


SPF-290S Analyzer SystemSpecifications

SPF-290S SPECIFICATIONSSource: Lamp .......................................................XenonCW Power ..............................125W(operatedat75W)

Detector: Type ....................................Multialkaliside-onPMT

Dimensions: SystemDimensions ........................46x32x35cm

Monochromator: Resolution ................................................. 1.66 nm WavelengthAccuracy ................................. ±0.2% SystemSpectralRange ............ 290nmto400nm WavelengthReproducibility ....................... 0.25nm

WinSPF VERSION 4.0 SOFTWARE

In August of 2007 the US Department of Health and Human Services, Food and Drug Administration proposed

Validation Kit

VALIDATION KITOptometrics is now offering a Comprehensive Test Plate for use with the SPF-290S and WinSPF version 4. The test plate is designed to provide the user with a clear understanding of how their SPF-290S analyzer is performing. The test plate contains several optical filters that are measured by the SPF-290S and the results are compared to NIST traceable factory measurements. Equipped with this tool, users will not spend time performing tests on an analyzer that is in need of repair nor will they spend money for repairs that are not necessary. In addition to the test plate, the Validation Kit contains TransporeTM tape, syringes and two standard formulations: 8% Homosalate and the Colipa Standard.

a UVA in-vitro testing procedure. The measurement takes the ratio of UVA 1 area per unit wavelength to UV area per unit wavelength.

WinSPF Release 4.0 performs the calculations and ratings prescribed in the Federal Register thus allowing the SPF-290S user to evaluate their products to ensure they conform to US Federal labeling guidelines.

Beginning with WinSPF Release 3.0, Optometrics software added the capability to make more than a single reference measurement, allowing up to 12 spatially separated measurements of the blank sample. With both the Boots Star rating and the new proposed Federal rules calling for the use of Taylor’s approximation for MPF and transmittance standard deviation reporting, WinSPF Release 4.0 calculates all MPF and transmittance standard deviations using this method when multiple references recipes are used. When a single reference scan is prescribed, WinSPF 4.0 performs the standard deviation evaluation in the more familiar manner.


SPF-290S Analyzer System TurnkeySystems

TURNKEY BASIC SYSTEMSPF-290SSunscreenProtectionFactorAnalyzerSystemandcomputercomprisedofa125WCWXenonsource,integratingsphere,colorcompensatingfilter,threesampleholders, scanning monochromator with stepping motor andcontroller,inaself-contained,attractivedesktopunit.Includesdataacquisitionboardanddrivers,I/O,communi-cationandpowercablesandWinSPFoperatingsoftware,four rolls of Transpore®tape(8-5010),aboxof25syringes(8-5015), new Validation Kit, and complete instructionmanual. WinSPF operating software also includes com-pleteon-linehelpsystem,fullyfunctionaltoolbar,singlestepcontrolicons,graphicalandtabulardatadisplayformatsand utilizes all Windows®multi-taskingfeatures.Availableforusewith110VAC,60Hz.(catalogno.8-5002)or220VAC,50Hz. (catalogno.8-5003).Computer includesaCPU,keyboard,monitor,mouse,andWindows® operating system.Dataacquisitionboard,driversandWinSPFv4.0software are installed and tested.

Windows® is a registered trademark of Microsoft CorporationTranspore® is a registered trademark of the 3M Corporation

TURNKEY AUTOMATED SYSTEMSPF-290SSunscreenProtectionFactorAnalyzerSystemandcomputercomprisedofa125WCWXenonsource,integratingsphere,colorcompensatingfilter,sixsampleholders, scanning monochromator with stepping motor and controller,X-YModuleandelectronicX-YControlModule,inaself-contained,attractivedesktopunit.Includesdataacquisitionboardanddrivers, I/O, communicationandpowercablesandWinSPFoperatingsoftware,fourrollsofTranspore®tape(8-5010),aboxof25syringes(8-5015),newvalidationkit,andcompleteinstructionmanual.Win-SPF operating software also includes complete on-line help system,fullyfunctionaltoolbar,singlestepcontrolicons,graphicalandtabulardatadisplayformatsandutilizesallWindows®multi-taskingfeatures.Availableforusewith110VAC,60Hz.(catalogno.8-5005)or220VAC,50Hz.(catalogno.8-5006).ComputerincludesaCPU,keyboard,monitor, mouse, and Windows®operatingsystem.Dataacquisition board, drivers and WinSPF v4.0 softwareinstalledandtested.IncludesnewValidationKit.

Detailsofsystemupgrades,accessories,replacementpartsandothersystemoptionsareonpage11.

Optometricswarrantiesallproductsagainstdefectsinmaterialandworkmanshipforoneyearfromthedateofpurchasewiththefollowingexception:LightSources-warrantiedfor3months.

Optometricsisnotliableforanyconsequentialorincidentaldamagearisingfromthesaleofitsproduct(s).Inanyevent,liabilityshallnotexceedtheinvoicevalueoftheproduct(s)sold.Accidentaldamage,neglect,unreasonableuse,attemptedservice,calibration,adjustmentsorcleaningnotexplicitlycalledforinaninstructionmanualvoidstheOptometricswarranty.

Optometricsmakesnowarrantyotherthandescribedaboveforitsproductsorfortheirperformanceinaspecificapplication.


SPF-290S Analyzer SystemSPF-290S Sunscreen Analyzer System

Consumables CATALOG NO. CONSUMABLES

8-5010 Transpore® Tape (3 inches x 10 yards) 4 rolls.

8-5015 Syringes with tips, 1 ml disposable (Lot of 25).

8-5078 HS8 (8%) Homosalate USFDA Standard SPF4 (1 oz Jar).

8-5079 Colipa Standard SPF 14-17 (1 oz Jar).

Accessories CATALOG NO. ACCESSORIES

8-5031 Sample holders for Transpore® Tape for use with X-Y stage, set of 3.

8-5032 Sample holder assemblies for Transpore® Tape for use without X-Y stage, set of 3.

8-5028 Quartz sample plates, 10.7 cm x 10.2 cm. Two plates/package.

8-5083 Validation Kit (Contains the following: a case, 10 syringes with tips, 1 roll of Transpore® Tape, calibration plate assembly, 1 oz of Homosalate Standard, and 1 oz of Colipa Standard).

8-5087 Calibration PlateAssembly (Includes 5 separate test filters).

Replacement Parts CATALOG NO. REPLACEMENT PARTS

8-5022 125W CW Xenon lamp replacement.

8-5095 Color compensating filter, annealed UG-5.

8-5094 SPF packaging/shipping materials.

Services & Upgrades CATALOG NO. SERVICESAND UPGRADES

8-5080 Training program at Optometrics facility, per diem. Client responsible for all travel expenses.

8-5081 On-site training, per diem. Travel expenses to be borne by client.

8-5084 WinSPF v4.0 software (on CD-ROM), OperatingManual and Validation Kit.

8-5085 Upgrade to WinSPF v4.0 from any Win SPF v2.xx and Validation Kit.

8-5086 Upgrade to WinSPF v4.0 from any Win SPF v3.xx and Validation Kit.

8-5026 X-Y stage upgrade (For SPF units purchased after December 2000).

RENT One month rental of SPF-290SAutomated (X-Y) system (8-5005 or 8-5006); 70% credit towards purchase allowed at end of rental period. Rental must be paid in advance.

www.lasercomponents.com 03/11 / V3 / HW / optometr/ spf-catalog.pdf


SPF-290S Analyzer System

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