***Some of the articles will be unavailable because agencies only keep them on their websites for a specified amount of time.***

Updates April 1-15, 2007Website SpotlightHHS Secretary Michael Leavitt unveils his personalized health care initiative at a Personalized Medicine Coalition luncheonhttp://www.ageofpersonalizedmedicine.org/knowledge_center/events/leavitt.asp

ArthritisAsthmaJournal article! DNA sequence variations of metalloproteinases: their role in asthma and COPDhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17403951&dopt=Abstract Journal article! Local genetic and environmental factors in asthma disease pathogenesis: chronicity and persistence mechanismshttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17400878&dopt=Abstract

CancerUniversity of Washington Center for Genomics and Public Health spotlight: Colon cancerhttp://www.cdc.gov/genomics/update/file/print/UWCGPH_2007_Mar_newsletter.pdf Journal article! Screening preferences of patients at familial risk of colorectal cancer http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17404844&dopt=Abstract Journal article! Genetic testing in colorectal cancer: who, when, how and whyhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17392593&dopt=Abstract Journal article! Impact of pharmacogenomics on clinical practice in oncologyhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17397243&dopt=Abstract April 12 – Massive gene screening points way to more effective chemotherapyhttp://www.sciencedaily.com/releases/2007/04/070411135042.htm April 11 – Genes gang up to help spread cancer, study findshttp://www.reutershealth.com/archive/2007/04/11/eline/links/20070411elin015.html April 10 – Genetic makeup predicts recurrence of cancerhttp://www.medicalnewstoday.com/medicalnews.php?newsid=67362 April 9 – Gene may mark breast cancer patients who can skip chemotherapyhttp://quote.bloomberg.com/apps/news?pid=10000080&sid=aQjaltW0nF9Q April 6 – Genetic disease test for newborns ok’dhttp://www.redorbit.com/news/health/894638/genetic_disease_tests_for_newborns_okd/index.html?source=r_healthApril 2 – Multiple genetic risk factors for prostate cancer foundhttp://www.news-medical.net/?id=22824

April 1 – 7 genetic risk factors found for prostate cancerhttp://www.msnbc.msn.com/id/17900096/from/ET/ April 1 – Researchers discover a common variation in a gene segment that increases the risk for prostate cancerhttp://www.nih.gov/news/pr/apr2007/nci-01b.htm

DiabetesJournal article! Family history of diabetes, awareness of risk factors, and health behaviors among African Americanshttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17395839&dopt=Abstract Journal article! Genetics of gestational diabetes mellitushttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17346148&dopt=Abstract Journal article! Building a bridge between clinical and basic research: the phenotypic elements of familial predisposition to type 1 diabeteshttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17346147&dopt=Abstract April 11 – Type 1 diabetics ditch insulin shots in Brazil experimenthttp://www.deseretnews.com/dn/view/0,1249,660210808,00.html April 2 – People who are pre-diabetic or who have Type 2 diabetes have much shorter telomereshttp://www.news-medical.net/?id=22837

Ethical IssuesJournal article! Genetics, insurance and participation: How a Citizens' Jury reached its verdicthttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17418469&dopt=Abstract Journal article! Human rights and ethics in genomic research: rethinking the modelhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17391075&dopt=Abstract April 12 – Hatch and Bennett vote yea as Senate oks stem cell billshttp://www.deseretnews.com/dn/view/0,1249,660211066,00.html April 9 – Stem cell fight should be pressed onhttp://www.sltrib.com/search/ci_5625180 April 3 – NY hospitals agree to informed consent about genetic testinghttp://www.northcountrygazette.org/articles/2007/040307GeneticTesting.html April 2 – Seniors at conference pepper U researcher on stem cellshttp://www.sltrib.com/search/ci_5577120

Family HistoryImportant news in the fight against breast cancer: Susan G. Komen for the cure debuts "News for the Cure" health video segmentshttp://www.prnewswire.com/broadcast/27666/consumer.shtml

Journal article! Communicating genetic information in families - a review of guidelines and position papershttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17392704&dopt=Abstract Journal article! Screening preferences of patients at familial risk of colorectal cancer http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17404844&dopt=Abstract Journal article! Factors associated with breast cancer-specific distress in younger women participating in a family history mammography screening programmehttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17410528&dopt=Abstract Journal article! The contribution of familial and heritable risks in heart failurehttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17413278&dopt=Abstract April 2 – Stalkers use DNA to fill in family treeshttp://deseretnews.com/dn/view/0,1249,660208204,00.html March 29 – Gene mutations linked to hereditary lung diseasehttp://www.sciencedaily.com/releases/2007/03/070329075229.htm March 28 – Knowledge of relatives’ health histories helpfulhttp://www.ourmidland.com/site/index.cfm?newsid=18137336&BRD=2289&PAG=461&dept_id=578054&rfi=8

Genetic TechnologyApril 9 – Two brothers suffer from rare genetic diseasehttp://wcco.com/local/local_story_099174216.html April 3 – Preparing for genetic testinghttp://www.upi.com/ConsumerHealthDaily/view.php?StoryID=20070403-050940-3860r March 30 – New glues to gene expression in cystic fibrosishttp://www.sciencedaily.com/releases/2007/03/070329075322.htm

Heart Disease and StrokeJournal article! A review of the genetics of essential hypertensionhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17413273&dopt=Abstract Journal article! Genetics of hypertrophic cardiomyopathy: one, two, or more diseases?http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17413275&dopt=Abstract Journal article! The genetics of congenital heart disease: a review of recent developmentshttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17413276&dopt=Abstract April 10 – No genetic link found for heart risk, study sayshttp://www.reuters.com/article/healthNews/idUSN1040908320070410?feedType=RSS April 10 – Study fails to verify gene variations as risk factors for certain cardiovascular problemshttp://www.eurekalert.org/pub_releases/2007-04/jaaj-sft040507.php April 3 – New genetic biomarkers could predict coronary heart disease

http://www.sciencedaily.com/releases/2007/04/070402102329.htm

Maternal and Child HealthApril is National Autism Awareness Monthhttp://www.cdc.gov/genomics/activities/monthly/april.htm Journal article! Newborn screening: a literature reviewhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17402600&dopt=Abstract Journal article! Heritability of autistic traits in the general populationhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17404134&dopt=Abstract April 6 – Genetic disease test for newborns ok’dhttp://www.redorbit.com/news/health/894638/genetic_disease_tests_for_newborns_okd/index.html?source=r_health April 5 – Spina bifida gene identified; groundbreaking research can make diagnosis easierhttp://www.sciencedaily.com/releases/2007/04/070405164600.htm April 4 – Emerging genetic research may help scientists recognize children with autism at a younger agehttp://www.news-medical.net/?id=23080 April 2 – Mutation in HNF4A associated with increase in birthweight and macrosomiahttp://www.eurekalert.org/pub_releases/2007-04/plos-mih032907.php

Mental HealthApril 10 – New study zeores in on the genetic roots of Alzheimer’s http://www.omrf.ouhsc.edu/OMRF/News_Releases/Releases/2007/20070410.asp April 9 – Genetic switch can control memoryhttp://www.sciencedaily.com/releases/2007/04/070405164911.htm April 1 – Brain tissue reveals possible genetic trigger for schizophreniahttp://www.medicalnewstoday.com/medicalnews.php?newsid=66535

NutrigenomicsJournal article! Nutrigenomics: concepts and applications to pharmacogenomics and clinical medicinehttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17391074&dopt=Abstract

ObesityApril 10 – Study finds dietary fat interacts with geneshttp://www.eurekalert.org/pub_releases/2007-04/tu-sfd040907.php

PharmacogenomicsJournal article! Nutrigenomics: concepts and applications to pharmacogenomics and clinical medicinehttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17391074&dopt=Abstract

Journal article! Impact of pharmacogenomics on clinical practice in oncologyhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17397243&dopt=AbstractJournal article! Pharmacogenomics and its implications for autoimmune diseasehttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17418528&dopt=Abstract April 12 – Massive gene screening points way to more effective chemotherapyhttp://www.sciencedaily.com/releases/2007/04/070411135042.htm

TobaccoJournal article! Effect of familial history and smoking on common cancer risks in Japanhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17410537&dopt=Abstract April 2 – NIDA study identifies genes that might help some people abstain from smokinghttp://www.nih.gov/news/pr/apr2007/nida-02b.htm

OtherJournal article! Gene-environment studies: any advantage over environmental studies?http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17389613&dopt=Abstract Journal article! Genomic health, inchttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17391076&dopt=Abstract Journal article! The future of genomic nursing researchhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17393961&dopt=Abstract Journal article! Establishing the essential nursing competencies for genetics and genomicshttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17393960&dopt=Abstract April 16 – Researchers discover gene crucial for nerve cell insulationhttp://www.nih.gov/news/pr/apr2007/nichd-16.htm April 10 – Scientists implicate gene in vitiligo and other autoimmune diseaseshttp://www.nih.gov/news/pr/apr2007/niams-10.htm April 9 – Tackling TAR: Families cope with rare genetic diseasehttp://www.herald-review.com/articles/2007/04/09/news/local_news/1022579.txt April 7 – New gene defect causes heavy boneshttp://www.medicalnewstoday.com/medicalnews.php?newsid=66999 April 6 – Dog genetics may offer cure clueshttp://www.sltrib.com/news/ci_5606776?source=rv April 6 – Genetic mutation makes little dogs littlehttp://www.deseretnews.com/dn/view/0,1249,660209436,00.html April 6 – Disease at root of McCoy feudinghttp://www.deseretnews.com/dn/view/0,1249,660209479,00.html

Updates March 16-31, 2007

Website Spotlight

ArthritisMarch 26 – Japan expert link osteoarthritis to gene varianthttp://www.reutershealth.com/archive/2007/03/26/eline/links/20070326elin009.html March 26 – Problem gene may cause arthritishttp://www.iol.co.za/index.php?set_id=1&click_id=117&art_id=nw20070325224528304C936199

Asthma

CancerJournal article! Missed opportunities: family history and behavioral risk factors in breast cancer risk assessment among a multiethnic group of womenhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17356960&dopt=Abstract Journal article! Screening patients with a family history of colorectal cancerhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17372801&dopt=Abstract March 28 – Breast MRIs urged for high-risk womenhttp://deseretnews.com/dn/view/0,1249,660206879,00.html March 28 – Yearly breast MRIs urged for 1.4 million women: New cancer guidelines advise pricey screening for those at high riskhttp://www.msnbc.msn.com/id/17818068/wid/11915773?GT1=9145 March 22 – Mutation to mismatch repair gene associated with colorectal cancerhttp://www.sciencedaily.com/releases/2007/03/070321161840.htm March 22 – Scientists find gene that may regulate colon cancerhttp://www.reutershealth.com/archive/2007/03/22/eline/links/20070322elin008.html March 19 – Twins cope with cancer genehttp://www.deseretnews.com/dn/view/0,1249,660204508,00.htmlMarch 19 – Center for research on early detection of, cure of ovarian cancer launcheshttp://www.newswise.com/articles/view/528188/?sc=rsmn March 19 – Notorious cancer gene may work by destroying messengerhttp://researchnews.osu.edu/archive/srcrelease.htm March 15 – Genetics of breast cancerhttp://abclocal.go.com/wls/story?section=health&id=5126973

DiabetesJournal article! Genotypes, obesity and type 2 diabetes - can genetic information motivate weight loss? A reviewhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17378723&dopt=Abstract

Ethical IssuesMarch 22 – House Ways and Means committee passes bill to prohibit genetic discrimination

http://www.eurekalert.org/pub_releases/2007-03/acoc-sel032307.php March 21 – Congress moves to ban genetic discriminationhttp://www.npr.org/templates/story/story.php?storyId=9041522 March 21 – Lawmakers seek regulations, standards for home DNA kitshttp://www.sun-sentinel.com/features/health/sfl-hlpdnatest21mar21,0,962703.story?coll=sfla-news-health March 18 – Facing life with a lethal genehttp://www.nytimes.com/2007/03/18/health/18huntington.html?pagewanted=1&_r=1&ref=health

Family HistoryJournal article! Missed opportunities: family history and behavioral risk factors in breast cancer risk assessment among a multiethnic group of womenhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17356960&dopt=AbstractMarch 26 – Gene linked to increase risk of strokehttp://www.eurekalert.org/pub_releases/2007-03/aaon-glt032007.php March 26 – Early action can stop colon cancerhttp://www.sltrib.com/search/ci_5521577 March 19 – Twins cope with cancer genehttp://www.deseretnews.com/dn/view/0,1249,660204508,00.html March 18 – Facing life with a lethal genehttp://www.nytimes.com/2007/03/18/health/18huntington.html?pagewanted=1&_r=1&ref=health March 15 – Screening catches young athlete’s heart troubleshttp://www.msnbc.msn.com/id/17629839/

Genetic TechnologyJournal article! What genome-wide association studies can do for medicinehttp://content.nejm.org/cgi/content/extract/356/11/1094 March 26 – Genetic test for disease: blessing and liabilityhttp://www.sabcnews.com/sci_tech/science/0,2172,146072,00.html March 22 – Genetic testinghttp://www.myfoxorlando.com/myfox/pages/News/Detail?contentId=2743153&version=3&locale=EN-US&layoutCode=VSTY&pageId=3.2.1 March 22 – Ultrathin film deliver DNA as possible gene therapy toolhttp://www.newswise.com/articles/view/528346/?sc=rssn

Heart Disease and StrokeJournal article! Genetics of salt-sensitive hypertensionhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17362668&dopt=Abstract March 27 – Who gets heart failure? Race takes back seat to diabetes and high blood pressurehttp://www.eurekalert.org/pub_releases/2007-03/jhmi-wgh032207.php March 26 – Gene linked to increase risk of stroke

http://www.eurekalert.org/pub_releases/2007-03/aaon-glt032007.php March 26 – Hemochromatosis gene linked to stroke riskhttp://www.reutershealth.com/archive/2007/03/26/eline/links/20070326elin031.html March 26 – Gene test shown to measure heart function after translpanthttp://www.cumc.columbia.edu/news/press_releases/Deng_ACC07.html March 24 – Studies explore lifestyle choices and heart riskshttp://www.eurekalert.org/pub_releases/2007-03/acoc-sel032307.php March 22 – Unilab probes genes’ link to high cholesterolhttp://www.philstar.com/philstar/BUSINESS200703224403.htm March 15 – Screening catches young athlete’s heart troubleshttp://www.msnbc.msn.com/id/17629839/

Maternal and Child HealthJournal article! The role of gene-environment interaction in predicting adverse pregnancy outcomehttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17369098&dopt=Abstract March 27 – Study describes new type of “semi-identical” twinshttp://news.yahoo.com/s/nm/20070327/hl_nm/twins_identical_dc_2 March 26 – Genetics of autismhttp://www.medicalnewstoday.com/medicalnews.php?newsid=66132 March 19 – Gene therapy for fetuses’ hopehttp://news.bbc.co.uk/1/hi/health/6458425.stm March 19 – Family’s blessing making progresshttp://www.sltrib.com/ci_5469137 March 18 – Gene mutations, autism linkedhttp://www.deseretnews.com/dn/view/0,1249,660204241,00.html March 16 – In Hispanic women, genetic variations linked to spontaneous preterm birthhttp://www.medicalnewstoday.com/medicalnews.php?newsid=65417 March 16 – Autism’s roots: mix of chance and geneticshttp://www.baltimoresun.com/news/health/bal-te.autism16mar16,0,5054409.story?track=rss

Mental HealthJournal article! Knowledge of and attitudes about Alzheimer disease genetics: report of a pilot survey and two focus groupshttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17380059&dopt=Abstract Journal article! Pharmacogenetic studies of antidepressant response: how far from the clinic?http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17362808&dopt=Abstract March 26 – Genetic risk for schizophrenia uncovered by Feinstein researchershttp://www.medicalnewstoday.com/medicalnews.php?newsid=65672 March 18 – Facing life with a lethal gene

http://www.nytimes.com/2007/03/18/health/18huntington.html?pagewanted=1&_r=1&ref=health

NutrigenomicsJournal article! Nutrigenomics - 2006 updatehttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17378721&dopt=Abstract Journal article! Nutri-epigenomics: lifelong remodelling of our epigenomes by nutritional and metabolic factors and beyondhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17378726&dopt=Abstract March 23 – Better eating through genomicshttp://money.cnn.com/2007/03/22/news/companies/pluggedin_boyle_wellgen.fortune/index.htm?section=money_email_alerts

Obesity Journal article! Addressing the obesity epidemic: a genomics perspectivehttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17362622&dopt=Abstract Journal article! Genotypes, obesity and type 2 diabetes - can genetic information motivate weight loss? A reviewhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17378723&dopt=Abstract Journal article! The V103I polymorphism of the MC4R gene and obesity: population based studies and meta-analysis of 29 563 individualshttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17356525&dopt=Abstract March 26 – Keeping Kate sated, safe: Insatiable appetite is huge challenge for S.L. girl with Prader-Willihttp://deseretnews.com/dn/view/1%2C1249%2C660206237%2C00.html March 18 – The difference between fat and thin geneshttp://in.news.yahoo.com/070318/139/6dfwn.html

PharmacogenomicsJournal article! Pharmacogenetic studies of antidepressant response: how far from the clinic?http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17362808&dopt=AbstractJournal article! Steroid hormone receptor gene polymorphisms and osteoporosis: a pharmacogenomic reviewhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17376011&dopt=Abstract

Tobacco

Other

Journal article! Educating health care professionals about genetics and genomicshttp://www.genome.gov/Pages/News/Documents/Guttmacheretal.pdf March 26 – Fifth National DNA Day to showcase genomic discoveries and careershttp://www.nih.gov/news/pr/mar2007/nhgri-26.htm March 25 – Scientists study memory, genetic linkhttp://www.localtechwire.com/news/state/story/1247325/ March 22 – A visionary who led a genetic revolutionhttp://www.latimes.com/news/obituaries/la-me-wexler22mar22,0,7387351.story?page=1&coll=la-home-obituaries March 22 – US healthcare provider plans large genetics research programhttp://www.phgu.org.uk/ecard.php?link_ID=3201 March 21 – The genome’s quirky geniushttp://www.theaustralian.news.com.au/story/0,20867,21417232-12332,00.html March 19 – Genetic link to heavy substance abuse in teenagershttp://www.sciencedaily.com/releases/2007/03/070319074317.htm March 17 – Genes plus parenting may promote shyness, anxietyhttp://www.reutershealth.com/archive/2007/03/15/eline/links/20070315elin003.html

Updates March 1 – 15, 2007Website SpotlightMarch is National Colorectal Cancer Awareness Monthhttp://www.cdc.gov/genomics/activities/monthly/march.htm

Arthritis

AsthmaJournal article! The genetics of bronchial asthma in childrenhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17353123&dopt=Abstract

CancerJournal article! Cancer genetics clinics and the surgeon: a valuable role for family history screeninghttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17346404&dopt=AbstractJournal article! Time to decide about risk-reducing mastectomy: A case series of BRCA1/2 gene mutation carriershttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17341306&dopt=Abstract Journal article! Early Initiation of colorectal cancer screening in individuals with affected first-degree relativeshttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17351851&dopt=Abstract Journal article! The challenge of evaluating annual mammography screening for young women with a family history of breast cancer

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17217606&dopt=AbstractMarch 14 – Colon cancer risk: It’s often all in the familyhttp://www.newswise.com/articles/view/527643/?sc=rsmnMarch 14 – Drivers and passengers on the road to cancerhttp://www.eurekalert.org/pub_releases/2007-03/wtsi-dap030507.phpMarch 14 – Life-saving cancer genetic testing vastly underutilizedhttp://www.medicalnewstoday.com/medicalnews.php?newsid=64539March 14 – Researchers find the mechanism by which cells resist chemotherapyhttp://www.eurekalert.org/pub_releases/2007-03/uadb-rft030207.php March 13 – Ovarian cancer may mimic fallopian tube formationhttp://www.sciencedaily.com/releases/2007/03/070307075616.htm March 12 – Gene discovery sheds light on pancreatic cancer http://www.nlm.nih.gov/medlineplus/news/fullstory_46453.html March 8 – Gene shopping: Parents won’t pass on deadly diseases with new procedureshttp://abcnews.go.com/GMA/story?id=2932593&page=1 March 8 – More gene mutations drive cancer than previously thoughthttp://www.medicalnewstoday.com/healthnews.php?newsid=64804 March 6 – Few women aware of hereditary cancer hazardshttp://www.medpagetoday.com/HematologyOncology/OtherCancers/dh/5197

DiabetesMarch 14 – Type 1 diabetes genetic risk much higher than previous estimateshttp://www.emaxhealth.com/23/10035.htmlMarch 14 – Genetic contributions to Type 2 diabetes: recent insights.http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17331067&dopt=Abstract

Ethical IssuesMarch 14 – Genetic conditions often lead to insurance refusalhttp://www.reutershealth.com/archive/2007/03/05/eline/links/20070305elin040.htmlMarch 12 – House subcommittee considers bill that would prohibit genetic discriminationhttp://www.medicalnewstoday.com/medicalnews.php?newsid=64905

Family HistoryJournal article! Cancer genetics clinics and the surgeon: a valuable role for family history screeninghttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17346404&dopt=Abstract Journal article! Relation of family history of myocardial infarction and the presence of coronary arterial calcium in various age and risk factor groupshttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17350375&dopt=AbstractMarch 14 – Colon cancer risk: It’s often all in the familyhttp://www.newswise.com/articles/view/527643/?sc=rsmn

March 14 – Family history of cancer in children with acute leukemia, Hodgkin's lymphoma or non-Hodgkin's lymphoma: The ESCALE study (SFCE).http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17330239&dopt=AbstractMarch 13 – Framingham study shows parents who live long pass on lower risk of cardiovascular diseasehttp://www.nih.gov/news/pr/mar2007/nhlbi-13.htm March 10 – Genetics may play a role in heart healthhttp://deseretnews.com/dn/view/0,1249,660202055,00.html March 5 – Extreme genealogy dazzleshttp://www.deseretnews.com/dn/view/0,1249,660200646,00.html

Genetic TechnologyMarch 14 – Mapping disease: Microarrays super-power genetic content analysishttp://www.econtentmag.com/Articles/ArticleReader.aspx?ArticleID=19253

Heart Disease and StrokeJournal article! Relation of family history of myocardial infarction and the presence of coronary arterial calcium in various age and risk factor groupshttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17350375&dopt=Abstract Journal article! A review of genetic causes of ischemic and hemorrhagic strokehttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17328915&dopt=AbstractMarch 14 – Single genetic defect causes early heart diseasehttp://www.eurekalert.org/pub_releases/2007-03/hhmi-sgd022607.phpMarch 9 – Genetics is often key to treatmenthttp://deseretnews.com/dn/view/0,1249,660201745,00.html March 10 – Genetics may play a role in heart healthhttp://deseretnews.com/dn/view/0,1249,660202055,00.html

Maternal and Child HealthJournal article! Sudden infant death syndrome: Review of implicated genetic factorshttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17340630&dopt=Abstract March 15 – Tiny, spontaneous gene mutations may boost autism riskhttp://www.nih.gov/news/pr/mar2007/nimh-15.htm March 14 – Toward a test for detecting in childhood the risk of developing bipolar disorder and schizophreniahttp://www.eurekalert.org/pub_releases/2007-03/ul-tat031407.php March 13 – Gene and a region of chromosome identified that may lead to autism in childrenhttp://www.news-medical.net/?id=22583 March 12 – Tot’s future a mystery: Boy’s genetic condition is so rare that family has no answershttp://www.deseretnews.com/dn/view/0,1249,660202504,00.html

March 12 – Grant to Yale from Simons Foundation to explore genetic causes of autismhttp://www.medicalnewstoday.com/medicalnews.php?newsid=65011 March 9 – Coping with son’s genetic disorderhttp://www.heraldextra.com/content/view/212522/ March 8 – Gene shopping: Parents won’t pass on deadly diseases with new procedureshttp://abcnews.go.com/GMA/story?id=2932593&page=1 March 5 – Public cord-blood bank to open at Uhttp://www.sltrib.com/search/ci_5362864 March 5 – Doctors hope to convince parents umbilical cords are the perfect gifthttp://www.sltrib.com/SEARCH/ci_5362865

Mental HealthMarch 14 – Blood tests may be possible for mental health conditionshttp://www.eurekalert.org/pub_releases/2007-03/uoi-btm030507.phpMarch 6 – Myriad boosted by Alzheimer’s resultshttp://www.deseretnews.com/dn/view/0,1249,660200861,00.html

Nutrigenomics

ObesityJournal article! Addressing the obesity epidemic: A genomics perspectivehttp://www.cdc.gov/pcd/issues/2007/apr/pdf/06_0068.pdf

PharmacogenomicsJournal article! Planning for a national effort to enable and accelerate discoveries in pharmacogenetics: the NIH Pharmacogenetics Research Networkhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17339874&dopt=Abstract Journal article! Should pharmacogenomic studies be required for new drug approval?http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17339872&dopt=Abstract

TobaccoMarch 14 – Gene test helps to diagnose lung cancer earlyhttp://www.medicalnewstoday.com/healthnews.php?newsid=64521

OtherJournal article! The role of genetics in the provision of essential public health serviceshttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17329649&dopt=AbstractJournal article! Searching for alleles associated with complicated outcomes after burn injuryhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17351434&dopt=Abstract Journal article! Predictive testing for Huntington's disease

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17352941&dopt=Abstract March 19 – Beyond stones and bones: How DNA is revealing new surprises about our ancestorshttp://www.msnbc.msn.com/id/17542627/site/newsweek/?GT1=9145March 14 – Genes may determine success of hip replacement therapyhttp://www.eurekalert.org/pub_releases/2007-03/bmj-gmd031407.php March 14 – Gene defect leads to an AIDS drughttp://www.boston.com/news/globe/health_science/articles/2007/03/05/gene_defect_leads_to_an_aids_drug/March 14 – Clemson DNA center opens todayhttp://greenvilleonline.com/apps/pbcs.dll/article?AID=/20070314/NEWS04/703140370 March 12 – Old vaccines may be better than newhttp://www.nature.com/news/2007/070312/full/070312-2.html March 9 – Gene variations contribute to aggression and anger in womenhttp://www.eurekalert.org/pub_releases/2007-03/uops-gvc030607.php March 8 – Migraine sufferers may have different genetic makeuphttp://www.press-citizen.com/apps/pbcs.dll/article?AID=/20070308/NEWS01/70308006 March 8 – Individual differences in a clock gene predict decline of performance during sleep deprivationhttp://www.eurekalert.org/pub_releases/2007-03/cp-idi030607.php March 6 – Funding for US children’s study back on trackhttp://deseretnews.com/dn/view/0,1249,660200895,00.html

Updates February 16-28, 2007Website SpotlightArthritisAsthmaJournal article! Knowledge and attitudes towards genetic testing: A two year follow-up study in patients with asthma, diabetes mellitus and cardiovascular diseasehttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17318450&dopt=AbstractFeb 27 – Gene plus mom’s smoking boosts child’s asthma riskhttp://www.reutershealth.com/archive/2007/02/27/eline/links/20070227elin001.html

CancerMarch is National Colon Cancer Awareness Monthhttp://www.cdc.gov/genomics/activities/monthly/march.htm Journal article! Family history of cancer and utilization of prostate, colorectal and skin cancer screening tests in U.S. menhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17320159&dopt=Abstract Journal article! Cancer geneticshttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17303511&dopt=Abstract

Journal article! Knowledge and expectations of women undergoing cancer genetic risk assessment: A qualitative analysis of free-text qQuestionnaire commentshttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17318449&dopt=Abstract Journal article! A single nucleotide polymorphism in the p53 pathway interacts with gender, environmental stresses and tumor genetics to influence cancer in humanshttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17322917&dopt=Abstract Journal article! BRCA1 promoter deletions in young women with breast cancer and a strong family history: A population-based studyhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17317153&dopt=Abstract Journal article! Development and pilot testing of two decision aids for individuals considering genetic testing for cancer riskhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17318456&dopt=Abstract Feb 28 – Estrogen gene affects risk of breast cancer but not CVDhttp://www.sciencedaily.com/releases/2007/02/070220014141.htmFeb 27 – Black men and prostate cancerhttp://www.startribune.com/484/story/1028190.html Feb 26 – Schanie's test results stir mixed emotionshttp://www.courier-journal.com/apps/pbcs.dll/article?AID=/20070226/FEATURES/702260370 Feb 22 – People with genetic predictors of colorectal cancer are not getting screened: More likely to get tested if directed to do so by their doctorhttp://www.medicalnewstoday.com/medicalnews.php?newsid=63660 Feb 20 – NCI Cancer Bulletin featuring several genomics related articleshttp://www.cancer.gov/ncicancerbulletin/NCI_Cancer_Bulletin_022007.pdf Feb 20 – Cancer cells 100 times more likely to genetically mutatehttp://www.news-medical.net/?id=22066 Feb 20 – Cell pathway identified which plays critical role in colon cancerhttp://www.news-medical.net/?id=22018 Feb 20 – Gene profiling predicts resistance to breast cancer drug Herceptinhttp://www.medicalnewstoday.com/medicalnews.php?newsid=63485 Feb 19 – Cancer is a stem cell issuehttp://www.news-medical.net/?id=21997 Feb 15 – Computer tool helps pinpoint risky gene mutationshttp://www.eurekalert.org/pub_releases/2007-02/jhu-cth021207.php Feb 14 – NCI Cancer Bulletin featuring several genomics related articleshttp://www.cancer.gov/ncicancerbulletin/NCI_Cancer_Bulletin_021407.pdf

DiabetesNew fact sheet from CDC: Does Diabetes Run in Your Family?http://www.cdc.gov/genomics/public/file/print/2007-02_Diabetes_Broch.pdf Spanish versionhttp://www.cdc.gov/genomics/public/file/print/2007-02_Diabetes_Broch_span.pdf

Journal article! Knowledge and attitudes towards genetic testing: A two year follow-up study in patients with asthma, diabetes mellitus and cardiovascular diseasehttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17318450&dopt=Abstract Feb 19 – Four genes identified that increase risk of developing Type 2 diabeteshttp://www.news-medical.net/?id=22006 Feb 19 – Elucidation of the genome for diabetes with DNA chipshttp://www.medicalnewstoday.com/medicalnews.php?newsid=63045

Ethical IssuesJournal article! Managing genetic discrimination: Strategies used by individuals found to have the Huntington disease mutationhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17309644&dopt=Abstract Journal article! Concern, pressure and lack of knowledge affect choice of not wanting to know high-risk statushttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17311083&dopt=Abstract Feb 20 – House committee approves bill to prevent genetic discriminationhttp://www.medicalnewstoday.com/medicalnews.php?newsid=63192 Feb 18 – Genetic tests offer promise, but raise questions toohttp://www.nytimes.com/2007/02/18/business/yourmoney/18reframe.html?_r=1&oref=slogin Feb 16 – House bill seeks to prohibit all new human genome patentinghttp://www.genomeweb.com/issues/news/138502-1.html

Family HistoryJournal article! Family history of cancer and utilization of prostate, colorectal and skin cancer screening tests in U.S. menhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17320159&dopt=AbstractJournal article! Cancer family history reporting: Impact of method and psychosocial factorshttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17318453&dopt=Abstract Feb 27 – Gene plus mom’s smoking boosts child’s asthma riskhttp://www.reutershealth.com/archive/2007/02/27/eline/links/20070227elin001.htmlFeb 22 – People with genetic predictors of colorectal cancer are not getting screened: More likely to get tested if directed to do so by their doctorhttp://www.medicalnewstoday.com/medicalnews.php?newsid=63660 Feb 21 – Study finds reduced brain growth in alcoholics with family drinking historyhttp://www.nih.gov/news/pr/feb2007/niaaa-21.htm Feb 21 – Sequencing human history: the genetics and commerce of personal ancestryhttp://www.medicalnewstoday.com/medicalnews.php?newsid=63375

Genetic Technology

Feb 27 – Genetic testing faces legal obstacles, doctors' limited expertisehttp://www.azcentral.com/business/articles/0227biz-biolaw0227.html Feb 27 – Gene therapy shows promise as treatment for diseased lower limbs at risk for amputationhttp://www.news-medical.net/?id=22216 Feb 25 – Study on uses for adult stem cells was flawed, panel sayshttp://www.deseretnews.com/dn/view/0,1249,660198505,00.html Feb 20 – Progress is reported on a type of autismhttp://www.nytimes.com/2007/02/20/health/20rett.html?ref=health Feb 20 – Low cost Parkinson’s disease diagnostic test a world firsthttp://www.news-medical.net/?id=22078 Feb 19 – Epigenetics to shape stem cell futurehttp://www.news-medical.net/?id=21996 Feb 19 – RNAi shows promise in gene therapyhttp://www.news-medical.net/?id=22010

Heart Disease and StrokeJournal article! Gene-environment interaction and its impact on coronary heart disease riskhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17306734&dopt=Abstract Journal article! Knowledge and attitudes towards genetic testing: A two year follow-up study in patients with asthma, diabetes mellitus and cardiovascular diseasehttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17318450&dopt=Abstract Feb 28 – Estrogen gene affects risk of breast cancer but not CVDhttp://www.sciencedaily.com/releases/2007/02/070220014141.htm Feb 26 – Gene variant keeps blood triglyceride levels lowhttp://news.yahoo.com/s/hsn/20070226/hl_hsn/genevariantkeepsbloodtriglyceridelevelslow Feb 25 – Irregular heartbeat linked to genetic mutationhttp://www.news-medical.net/?id=22163

Maternal and Child HealthJournal article! Genetic epidemiologic studies of preterm birth: guidelines for researchhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17306646&dopt=Abstract Journal article! Invited Commentary: Two Studies of Genetic Control of Birth Weight Where Large Data Sets Were Availablehttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17311800&dopt=Abstract Journal article! Genetic and environmental influences on birth weight, birth length, head circumference, and gestational age by use of population-based parent-offspring datahttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17311798&dopt=Abstract Feb 28 – Older fathers appear to raise risks of genetic disorders

http://www.iht.com/articles/2007/02/28/healthscience/snfert.php?page=1 Feb 27 – Gene plus mom’s smoking boosts child’s asthma riskhttp://www.reutershealth.com/archive/2007/02/27/eline/links/20070227elin001.htmlFeb 27 – Study points to genetics in disparities in preterm birthshttp://www.nytimes.com/2007/02/27/health/27birt.html?_r=1&ref=health&oref=slogin Feb 24 – Leaders meet to discuss emergency preparedness for newborn screening and genetic serviceshttp://www.medicalnewstoday.com/medicalnews.php?newsid=63773 Feb 20 – Parents urged to donate cord bloodhttp://www.deseretnews.com/dn/view/0,1249,660197141,00.html Feb 20 – Newborns with respiratory distress potentially have rare genetic diseasehttp://www.eurekalert.org/pub_releases/2007-02/wuso-nwr022007.php Feb 19 – Autism gene found?http://www.deseretnews.com/dn/view/0,1249,660196873,00.html Feb 19 – Results of largest ever genome study of autism releasedhttp://www.news-medical.net/?id=21999 Feb 19 – International study finds autism genetic linkshttp://www.reutershealth.com/archive/2007/02/19/eline/links/20070219elin015.html Feb 18 – Largest ever search for autism genes reveal new clueshttp://www.nih.gov/news/pr/feb2007/nimh-18.htm

Mental HealthJournal article! Current applications of clinical genetic testing for psychiatric practicehttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17305105&dopt=AbstractFeb 26 – Schizophrenia linked to geneshttp://www.latimes.com/features/printedition/health/la-he-briefly26.2feb26,1,4716550.story?coll=la-headlines-pe-health&ctrack=1&cset=true Feb 26 – BU prof studies illness' genetics: Physical signs tied to schizophreniahttp://www.pressconnects.com/apps/pbcs.dll/article?AID=/20070226/NEWS01/702260318 Feb 20 – Genetic mutations make people susceptible to schizophreniahttp://www.news-medical.net/?id=22028 Feb 20 – Genetic tendency toward suicide linked to genome on chromosome 2http://www.news-medical.net/?id=22030

NutrigenomicsJournal article! Methodological aspects of the assessment of gene-nutrient interactions at the population levelhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17306733&dopt=Abstract Feb 27 – Genetic testing faces legal obstacles, doctors' limited expertisehttp://www.azcentral.com/business/articles/0227biz-biolaw0227.html

ObesityPharmacogenomics

Journal article! Current applications of clinical genetic testing for psychiatric practicehttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17305105&dopt=Abstract Journal article! Pharmacogenetics/genomics of membrane transporters in cancer chemotherapyhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17323126&dopt=Abstract Feb 20 – Researchers progress toward genetically guided treatment for cancerhttp://www.medicalnewstoday.com/medicalnews.php?newsid=63117

TobaccoJournal article! Aggregation of cancer among relatives of never-smoking lung cancer patientshttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17304511&dopt=Abstract Feb 27 – Gene plus mom’s smoking boosts child’s asthma riskhttp://www.reutershealth.com/archive/2007/02/27/eline/links/20070227elin001.html

Other Journal article! Addressing the issue of e-learning and online genetics for health professionalshttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17300540&dopt=Abstract Journal article! The human genome and understanding of common disease: present and future technologieshttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17322987&dopt=Abstract Feb 27 – Genetics might engineer path to successful aginghttp://www.miamiherald.com/299/story/24447.html Feb 21 – Anorexia nervosa may be genetichttp://www.news-medical.net/?id=22075 Feb 21 – Entire genetic blueprints of more than 2,000 human and avian influenza viruses completed and made publichttp://www.news-medical.net/?id=22092 Feb 21 – Scientists find new genes linked to Lou Gehrig’s diseasehttp://www.news-medical.net/?id=22088 Feb 20 – Researching the genetic and environmental causes behind deadly and disabling diseaseshttp://www.medicalnewstoday.com/medicalnews.php?newsid=63125 Feb 19 – Genetic testing sheds light on degenerative eye diseasehttp://www.medicalnewstoday.com/medicalnews.php?newsid=63042

Updates February 1-15, 207Website Spotlight

Arthritis

Journal article! Current thinking on genetics of chronic obstructive pulmonary diseasehttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17255800&dopt=Abstract

Asthma

CancerJournal article! Risk perception, worry and satisfaction related to genetic counseling for hereditary cancerhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17279329&dopt=Abstract Journal article! Retention and use of breast cancer recurrence risk information from genomic tests: The role of health literacyhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17267389&dopt=Abstract Journal article! Pharmacogenetics and oncology treatment for breast cancerhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17257083&dopt=AbstractFeb 13 – Variation in gene caspase-8 may help protect against breast cancerhttp://www.news-medical.net/?id=21884 Feb 11 – Variation in a gene may help protect against breast cancerhttp://www.nih.gov/news/pr/feb2007/nci-11.htm Feb 9 – Cold Spring Harbor Laboratory scientists discover new gene that prevents multiple types of cancerhttp://www.medicalnewstoday.com/medicalnews.php?newsid=62638&nfid=mnf Feb 6 – Cancer stem cells found in pancreatic tumorshttp://www.cancer.gov/ncicancerbulletin/NCI_Cancer_Bulletin_020607.pdf Feb 6 – New test predicts chances of breast cancer return: Based on a woman’s genetic profilehttp://health.msn.com/centers/breastcancer/articlepage.aspx?cp-documentid=100154838&GT1=9085 Feb 1 – Genetic fingerprints identify brain tumor’s originshttp://mednews.wustl.edu/news/page/normal/8655.html?emailID=13020

DiabetesJournal article! Application of nutrigenomic concepts to Type 2 diabetes mellitushttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17276047&dopt=Abstract Feb 11 – Type 2 diabetes gene identifiedhttp://www.news-medical.net/?id=21821 Jan 31 – Study tests oral insulin to prevent Type 1 diabeteshttp://www.nih.gov/news/pr/jan2007/niddk-31.htm Jan 28 – 50% of Americans have gene that affects how body burns sugarhttp://www.news-medical.net/?id=21506

Ethical Issues

Journal article! GINA aGAINhttp://www.nature.com/ng/journal/v39/n2/pdf/ng0207-133.pdf Journal article! Access to health insurance: Experiences and attitudes of those with genetic versus non-genetic medical conditionshttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17290434&dopt=Abstract Feb 16 – House bill seeks to prohibit all new human genome patentinghttp://www.genomeweb.com/issues/news/138502-1.html Feb 13 – Patenting lifehttp://www.nytimes.com/2007/02/13/opinion/13crichton.html?ex=1329022800&en=529819d2eacd005f&ei=5124&partner=permalink&exprod=permalink Feb 12 - Individuals with genetic conditions twice as likely to report health insurance denialhttp://www.eurekalert.org/pub_releases/2007-02/jhu-iwg021207.php

Family HistoryFeb 15 – Survey finds perceived risk of recurrence low in African American breast cancer survivorshttp://www.eurekalert.org/pub_releases/2007-02/aafc-sfp021407.php Feb 4 – Want to fight? Scientists say it’s all in your geneshttp://www.timesonline.co.uk/tol/news/uk/article1323843.ece Jan 31 – Study tests oral insulin to prevent Type 1 diabeteshttp://www.nih.gov/news/pr/jan2007/niddk-31.htmJan 29 – Ehlers-Danlos syndrome: Connective tissue disorder comes in many formshttp://www.deseretnews.com/dn/view/0,1249,655191611,00.html

Genetic TechnologyFeb 13 – Injured teen treated in China: Brain-injured girl gets stem cell therapieshttp://www.deseretnews.com/dn/view/0,1249,660195150,00.html Feb 7 – New test shows which breast cancers will reoccurhttp://www.news-medical.net/?id=21766 Feb 6 – Stimulating human metabolismhttp://www.bioresearchonline.com/content/news/article.asp?docid=f3bd7ce5-305a-4de7-8d9b-c6996217d2f0&atc~c=771+s=773+r=001+l=a&VNETCOOKIE=NO Feb 5 – Gene therapy touristshttp://www.newstatesman.com/200702050026 Jan 31 – Genetic tests may bring hope, inspire fearhttp://www.cnn.com/2007/HEALTH/01/18/genetic.testing/index.html?eref=rss_health Jan 28 – RNA used to turn on genes to alleviate diseasehttp://www.news-medical.net/?id=21527

Heart Disease and StrokeFebruary is American Heart Month http://www.cdc.gov/genomics/events/special2.htm Genetic testing and the prevention of coronary heart disease: a case studyhttp://www.cdc.gov/genomics/activities/ogdp/2003/chap07.htm

Jim’s story: A family history of coronary heart diseasehttp://www.hhs.gov/familyhistory/docs/HDcasestudy_v2.pdf Journal article! Genomics and the cardiac surgeonhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17239225&dopt=Abstract Journal article! Heritability of ischaemic stroke in women compared with men: a genetic epidemiological studyhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17239799&dopt=Abstract Journal article! Gene polymorphisms and susceptibility to coronary artery diseasehttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17262794&dopt=Abstract Feb 14 – Brigham team devises model to better gauge heart riskhttp://www.boston.com/news/nation/articles/2007/02/14/brigham_team_devises_model_to_better_gauge_heart_risk/ Feb 7 – International consortium to get to heart of coronary artery diseasehttp://www.news-medical.net/?id=21778 Feb 6 – Researchers identify 5 genetic variations associated with risk of venous thrombosis in womenhttp://www.eurekalert.org/pub_releases/2007-02/jaaj-rif020107.php Feb 5 – Gene lined to blood pressurehttp://www.earthtimes.org/articles/show/27600.html Feb 2 – Study finds genetic link to women’s heart diseasehttp://www.insidebayarea.com/ci_5141874?source=rss Jan 31 – Mayo Clinic research shows 35% of 49 young people who died suddenly an inexplicably had genetic heart defectshttp://www.medicalnewstoday.com/medicalnews.php?newsid=61959 Jan 30 – Medical mystery: Genetic secret to a long life?http://abcnews.go.com/Health/story?id=2832781&page=1

Maternal and Child HealthFeb 11 – New diagnostic technology for routine prenatal genetic testinghttp://www.news-medical.net/?id=21801 Feb 8 – Genes may trigger repeated premature births in blackshttp://www.stltoday.com/stltoday/news/stories.nsf/sciencemedicine/story/72E0A40AF91BF5498625727D00105ABF?OpenDocument Feb 8 – Utah autism rate among highest; increases twentyfold in 20 yearshttp://deseretnews.com/dn/view/0,1249,660193816,00.html Feb 5 – Apolipoprotein E gene raises newborns’ cerebral palsy riskhttp://www.news-medical.net/?id=21673 Feb 1 – New Down’s test eliminates miscarriage riskhttp://news.yahoo.com/s/nm/20070202/hl_nm/pregnancy_test_dc_1 Jan 29 – Gene could predict ADHD drug reactionhttp://news.ninemsn.com.au/article.aspx?id=62843

Mental Health

Journal article! The genomic era and serious mental illness: a potential application for psychiatric genetic counselinghttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17287384&dopt=Abstract Journal article! Pharmacogenetics of antipsychotics: useful for the clinician?http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17278909&dopt=Abstract Journal article! Molecular genetics of bipolar disorder and depressionhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17239033&dopt=Abstract Feb 14 – Study identifies gene variation for mild form of schizophreniahttp://news.sawf.org/Health/33443.aspx Feb 8 – Common gene version optimizes thinking but with a possible downsidehttp://www.nih.gov/news/pr/feb2007/nimh-08.htm Feb 1 - Standford led study closes in on severe depression genehttp://www.genengnews.com/news/bnitem.aspx?name=12105866

NutrigenomicsJournal article! Application of nutrigenomic concepts to Type 2 diabetes mellitushttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17276047&dopt=AbstractJan 29 – Let your genes become your diet experthttp://www.siasat.com/english/index.php?option=content&task=view&id=153744&Itemid=76&cattitle=Health

ObesityJournal article! Genetic susceptibility to obstructive sleep apnea in the obese childhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17275401&dopt=Abstract Feb 13 – A unique twin study on the increased risk cardiometabolic risk in obesityhttp://www.eurekalert.org/pub_releases/2007-02/plos-aut020907.php

PharmacogenomicsJournal article! Pharmacogenetics and oncology treatment for breast cancerhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17257083&dopt=Abstract Journal article! Pharmacogenomics of cancer chemotherapy-induced toxicityhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17265780&dopt=Abstract Feb 2 – Has personalized medicine arrived?http://www.technologyreview.com/blog/post.aspx?id=17517&author=duncan

TobaccoFeb 12 – Hooked by genes: Studies identify DNA regions linked to nicotine dependencehttp://www.sciencedaily.com/releases/2007/02/070210173501.htm

Jan 25 – Calculated risk: Scientists discover genetic risk factor for smoking-linked head and neck cancerhttp://www.sciencedaily.com/releases/2007/01/070124120917.htm

OtherJournal article! Genetic polymorphisms and disease preventionhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17252563&dopt=Abstract Journal article! Assessing the informational needs of adolescents with a genetic condition: What do they want to know?http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17277993&dopt=Abstract Journal article! Human genetics of infectious diseases: a unified theoryhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17255931&dopt=Abstract Feb 14 – Kaiser launches genetics studyhttp://www.siliconvalley.com/mld/siliconvalley/business/technology/16699429.htm?source=rss&channel=siliconvalley_technology Feb 13 – Genetic testing sheds light on degenerative eye diseasehttp://www.eurekalert.org/pub_releases/2007-02/uomh-utg021307.php Feb 8 – Second gene discovered for recessive form of brittle bone diseasehttp://www.nih.gov/news/pr/feb2007/nichd-08.htm Feb 5 – Gene researchhttp://www.telegraph.co.uk/news/main.jhtml?xml=/news/2007/02/05/nblfu505.xml Feb 1 – More bingers than anorexics, study sayshttp://www.deseretnews.com/dn/view/0,1249,660191677,00.html Jan 30 – Study finds genes that predict transplant rejectionhttp://www.ctv.ca/servlet/ArticleNews/story/CTVNews/20070130/marrow_transplants_070130/20070130?hub=Canada Jan 29 – Insight into ethnic differenceshttp://www.nih.gov/news/research_matters/january2007/01292007ethnic.htm Jan 29 – U scientists describe nerve breakage in “Lincoln’s disease”http://www.deseretnews.com/dn/view/0,1249,655192244,00.html Jan 29 – Salmonella survives better in stomach due to altered DNAhttp://www.nwo.nl/nwohome.nsf/pages/NWOA_6X9EWV_Eng Jan 25 – Genes play bigger role than environment in anorexiahttp://www.reutershealth.com/archive/2007/01/25/eline/links/20070125elin025.html

Updates January 16-31, 2007Website SpotlightCancer Risk: Understanding the puzzlehttp://understandingrisk.cancer.gov/!!!start.cfm Updates on the Genetic Information Nondiscrimination Acthttp://www.geneticfairness.org/index.html

Arthritis

Jan 21 – Cracking open the black box of autoimmune diseasehttp://www.eurekalert.org/pub_releases/2007-01/wifb-cot011607.php

AsthmaJournal article! Gene environmental interaction in asthmahttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17218815&dopt=Abstract Journal article! Identifying novel genes contributing to asthma pathogenesishttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17218814&dopt=Abstract

CancerJournal article! Cancer risks among BRCA1 and BRCA2 mutation carriershttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17213823&dopt=Abstract Journal article! Familial effects of BRCA1 genetic mutation testing: changes in perceived family functioninghttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17220342&dopt=Abstract Journal article! Lifestyle behaviors in women with a BRCA1 or BRCA2 genetic mutation: an exploratory study guided by concepts derived from the Health Belief Modelhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17235212&dopt=Abstract Journal article! Pharmacogenomics in cancer treatment defining genetic bases for inter-individual differences in responses to chemotherapyhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17224657&dopt=Abstract Journal article! Family history is neglected in the work-up of patients with colorectal cancer: a quality assessment using cancer registry datahttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17237905&dopt=AbstractJournal article! Cost-effectiveness of surveillance programs for families at high and moderate risk of hereditary non-polyposis colorectal cancerhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17234021&dopt=Abstract Jan 21 – Your genes and breast cancerhttp://abclocal.go.com/kfsn/story?section=health&id=4913091 Jan 19 – Gene tests predicts survival chanceshttp://www.thestar.co.za/index.php?fArticleId=3634412Jan 17 – Fact sheet: A new era in cancer preventionhttp://www.whitehouse.gov/news/releases/2007/01/20070117-1.html Jan 17 - Genetic tests may make pap smears less vitalhttp://www.iht.com/articles/2007/01/17/healthscience/snpap.php Jan 15 - Schanie and her sisters wait, wonder after genetic testshttp://www.courier-journal.com/apps/pbcs.dll/article?AID=/20070115/FEATURES/701150312

DiabetesJournal article! Association between parental histories of hypertension, diabetes and dyslipidemia and the clustering of these disorders in offspringhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16510177&dopt=AbstractJan 21 – Cracking open the black box of autoimmune diseasehttp://www.eurekalert.org/pub_releases/2007-01/wifb-cot011607.phpJan 14 – Accuracy of gene expression test for heart transplant patients confirmedhttp://www.medicalnewstoday.com/medicalnews.php?newsid=60724

Ethical IssuesJournal article! The ethical implications of stratifying by race in pharmacogenomicshttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17186010&dopt=Abstract Jan 23 – My brother my saviourhttp://www.dailymail.co.uk/pages/live/articles/health/womenfamily.html?in_article_id=430673&in_page_id=1774&ito=1490 Jan 12 – Stem cell bill sails through House but faces presidential vetohttp://www.heraldextra.com/content/view/206393/

Family HistoryJournal article! Association between parental histories of hypertension, diabetes and dyslipidemia and the clustering of these disorders in offspringhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16510177&dopt=Abstract Journal article! Family history is neglected in the work-up of patients with colorectal cancer: a quality assessment using cancer registry datahttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17237905&dopt=Abstract Jan 24 – Genes modified by diethttp://www.smh.com.au/news/diet/genes-modified-by-diet/2007/01/17/1168709825115.html Jan 15 - Schanie and her sisters wait, wonder after genetic testshttp://www.courier-journal.com/apps/pbcs.dll/article?AID=/20070115/FEATURES/701150312Jan 12 – The biological clock is genetically determinedhttp://news.softpedia.com/news/The-Biological-Clock-is-Determined-Genetically-44289.shtml

Genetic TechnologyJan 23 – New web-based genomics tool designed to help predict disease susceptibilityhttp://www.genengnews.com/news/bnitem.aspx?name=11707647 Jan 20 – Quest Diagnostics announces licensing agreement for genetic testing technology to screen Fragile X syndromehttp://www.medicalnewstoday.com/medicalnews.php?newsid=61228

Jan 19 – Gene tests predicts survival chanceshttp://www.thestar.co.za/index.php?fArticleId=3634412 Jan 18 – Simple diagnostic test detects genetic signs of lung cancer in sputumhttp://www.news-medical.net/?id=21424 Jan 17 – Scientists map gene regulatorshttp://www.redorbit.com/news/health/803926/scientists_map_gene_regulators/index.html?source=r_health

Heart Disease and StrokeJournal article! Association between parental histories of hypertension, diabetes and dyslipidemia and the clustering of these disorders in offspringhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16510177&dopt=AbstractJournal article! Familial premature coronary artery disease mortality and obstructive sleep apneahttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17218564&dopt=Abstract Journal article! Genetics of ischaemic strokehttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17239802&dopt=Abstract Jan 22 – Genetic medicine: Some heart patients get DNA tests to determine correct drug dosehttp://www.redorbit.com/news/health/810818/genetic_medicine__some_heart_patients_get_dna_tests_to/index.html?source=r_health Jan 16 – Creating genetic medicinehttp://www.washingtontimes.com/metro/20070115-102959-2148r.htm Jan 16 – Masonic lab finds genetic basis for heart attackshttp://www.uticaod.com/apps/pbcs.dll/article?AID=/20070116/NEWS/701160322

Maternal and Child HealthJournal article! Family history of cardiovascular disease is associated with cardiovascular responses to stress in healthy young men and womenhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17234292&dopt=Abstract Jan 21 – Life altering birth defects topic at Uhttp://deseretnews.com/dn/view/0,1249,650224688,00.html Jan 17 – Early treatment of autism hinges on genetic discoverieshttp://www.dispatch.com/science/science.php?story=dispatch/2007/01/16/20070116-D5-04.html

Mental HealthJan 23 – Scientists identify gene that may indicate predisposition to schizophreniahttp://www.journals.uchicago.edu/press/012307_AJHG.html Jan 15 – New gene linked to Alzheimer’s disease identifiedhttp://news.yahoo.com/s/nm/20070115/ts_nm/alzheimers_gene_dc

Jan 15 – New gene uncovered for late-onset Alzheimer’s; findings replicated in four different ethnic groupshttp://www.sciencedaily.com/releases/2007/01/070114184533.htm

NutrigenomicsJournal article! Pharmacogenomics and nutrigenomics: synergies and differenceshttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17213870&dopt=Abstract Journal article! Nutrigenetics and nutraceuticals: the next wave riding on personalized medicinehttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17240315&dopt=Abstract Jan 24 – Genes modified by diethttp://www.smh.com.au/news/diet/genes-modified-by-diet/2007/01/17/1168709825115.html

ObesityJan 24 – Genes modified by diethttp://www.smh.com.au/news/diet/genes-modified-by-diet/2007/01/17/1168709825115.htmlJan 18 – Scientists debunk so called “fat gene”http://abcnews.go.com/Health/Diet/story?id=2802503&page=1

PharmacogenomicsJournal article! Pharmacogenomics and nutrigenomics: synergies and differenceshttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17213870&dopt=AbstractJournal article! The ethical implications of stratifying by race in pharmacogenomicshttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17186010&dopt=AbstractJournal article! The PharmGKB: integration, aggregation, and annotation of pharmacogenomic data and knowledgehttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17185992&dopt=Abstract Journal article! Pharmacogenomics in cancer treatment defining genetic bases for inter-individual differences in responses to chemotherapyhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17224657&dopt=Abstract Jan 16 – Creating genetic medicinehttp://www.washingtontimes.com/metro/20070115-102959-2148r.htm

TobaccoJournal article! Overview of the pharmacogenomics of cigarette smokinghttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17224913&dopt=Abstract Jan 18 – Simple diagnostic test detects genetic signs of lung cancer in sputum

http://www.news-medical.net/?id=21424

OtherJournal article! Public Health Genomics. The integration of genome-based knowledge into public health research, policies and health serviceshttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17225989&dopt=Abstract Jan 24 – BioServe, Harvard, and University of Michigan to determine links between genetics and lead exposurehttp://www.genengnews.com/news/bnitem.aspx?name=11748926 Jan 24 – New gene implicated in Chron’s diseasehttp://www.genengnews.com/news/bnitem.aspx?name=11748928 Jan 23 – Amid awareness campaigns, need for new methods evidenthttp://www.sltrib.com/health/ci_5064158 Jan 22 – U to get funds to better science educationhttp://www.sltrib.com/news/ci_5060114 Jan 22 – Gene key offers hope to heroin addictshttp://www.thewest.com.au/default.aspx?MenuID=28&ContentID=19365 Jan 22 – New study investigates link between fatigue, genes, and athletic performancehttp://www.medicalnewstoday.com/medicalnews.php?newsid=61261 Jan 22 – H5N1 genetic mutation observed in Egypthttp://www.news-medical.net/?id=21440 Jan 17 – Genomics and public health at CDChttp://www.redorbit.com/news/health/803942/genomics_and_public_health_at_cdc/index.html?source=r_health Jan 16 – Macular degeneration has a strong genetic linkhttp://www.reutershealth.com/archive/2007/01/16/eline/links/20070116elin002.html Jan 16 – Researchers find a common genetic risk factor for Parkinson’s disease in Asianshttp://www.mayoclinic.org/news2007-jax/3883.htmlJan 16 – Midstate briefs: Genetic mutations may cause SIDShttp://tennessean.com/apps/pbcs.dll/article?AID=/20070116/NEWS01/701160352 Jan 11 – Scientists find potential “off” switch for HIV virushttp://www.eurekalert.org/pub_releases/2007-01/pu-sfp011107.php

Updates January 1-15, 2007Website SpotlightQuestion of the year: What would you do if it became possible to sequence the equivalent of a full human genome for only $1000?http://www.nature.com/ng/qoty/index.html

Arthritis

AsthmaJournal article! Genetic predisposition to asthma and atopy

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17190999&dopt=Abstract Journal article! Genes, environment, development and asthma: a reappraisalhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17197483&dopt=Abstract Journal article! African americans with asthma: genetic insightshttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17202293&dopt=Abstract Journal article! Gene-environment interactions in asthma: with apologies to william of ockhamhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17202288&dopt=Abstract

CancerJournal article! In search of a familial cancer risk assessment toolhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17204050&dopt=Abstract Jan 9 – Study examines genetic factors associated with head and neck cancerhttp://www.eurekalert.org/pub_releases/2007-01/jaaj-seg010407.php Jan 9 – USC study in Nature Genetics supports a stem cell origin of cancerhttp://www.eurekalert.org/pub_releases/2007-01/uosc-usi010807.php Jan 8 – Scientists find guardian gene’s choices crucial to stopping cancer processhttp://www.sciencedaily.com/releases/2007/01/070108093906.htm Jan 5 – Rogue gene linked to breast and childhood cancer riskhttp://www.medicalnewstoday.com/medicalnews.php?newsid=60017 Jan 4 – Gene test devised to predict lung cancer relapse riskhttp://in.news.yahoo.com/070104/139/6atkd.html Jan 4 – British gene team are on the brink of cancer breakthroughhttp://www.mailonsunday.co.uk/pages/live/articles/health/healthmain.html?in_article_id=426399&in_page_id=1774&in_a_source= Jan 3 – Five-gene signature linked to survival in NSCLChttp://www.medpagetoday.com/Pulmonary/LungCancer/tb/4799 Jan 3 – Men with no sons more at risk for prostate cancer, according to Mailman School of PH studyhttp://www.eurekalert.org/pub_releases/2007-01/cums-mwn122906.php Dec 28 – New genetic test predicts risk of metastasis in patients with deadly eye cancerhttp://www.sciencedaily.com/releases/2006/11/061116100809.htm

DiabetesJournal article! Increased risk of Type 2 diabetes from a family history of coronary heart disease and Type 2 diabeteshttp://care.diabetesjournals.org/cgi/content/extract/30/1/154 Jan 9 – Researchers identify gene associated with severe kidney failure in diabeteshttp://www.eurekalert.org/pub_releases/2007-01/wfub-rig010907.php

Ethical Issues

Jan 12 – Stem cell research: Funding measure passes Househttp://www.sltrib.com/news/ci_4998528 Jan 12 – House oks greater stem cell usehttp://www.deseretnews.com/dn/view/0,1249,650222259,00.html Jan 6 – Analysis: Gene tests put docs at riskhttp://www.redorbit.com/news/health/790558/analysis_gene_tests_put_docs_at_risk/index.htmlJan 2 – NPR series examines use, ethics of preimplantation genetic diagnosis for embryonic disease screening, sex selectionhttp://www.medicalnewstoday.com/medicalnews.php?newsid=59668&nfid=mnf

Family HistoryJournal article! Increased risk of Type 2 diabetes from a family history of coronary heart disease and Type 2 diabeteshttp://care.diabetesjournals.org/cgi/content/extract/30/1/154Jan 4 – January is national birth defects prevention month and family health history monthhttp://www.michigan.gov/mdch/0,1607,7-132-8347-159571--,00.html Jan 3 – Parents may pass along not just DNAhttp://www.redorbit.com/news/science/786767/parents_may_pass_along_not_just_dna/index.html?source=r_science Dec 30 – Exercise response varies with genetics – study identifies genes and mutations associated with exercise traitshttp://www.medicalnewstoday.com/medicalnews.php?newsid=59439

Genetic TechnologyJan 8 – Scientists find new source of stem cellshttp://www.deseretnews.com/dn/view/0,1249,650221167,00.html Jan 8 – Bringing Tori back: Utah teen going to China for stem cell treatmenthttp://www.deseretnews.com/dn/view/0,1249,650221166,00.html Jan 5 – U expert says stem cell progress a slow-gohttp://www.deseretnews.com/dn/view/0,1249,650220505,00.html Jan 3 – Test could gauge risk in patients with lung cancerhttp://www.usatoday.com/news/health/2007-01-03-lung-cancer-test_x.htm Jan 2 – Hazy future for genetic drugs, testshttp://www.mercurynews.com/mld/mercurynews/business/16365391.htm?source=rss

Heart Disease and StrokeJournal article! Increased risk of Type 2 diabetes from a family history of coronary heart disease and Type 2 diabeteshttp://care.diabetesjournals.org/cgi/content/extract/30/1/154Journal article! Sudden cardiac death in the young: a clinical genetic approachhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17199842&dopt=Abstract Jan 12 – Personalizing medicine: Testing how genes affect warfarin dose

http://www.nj.com/newsflash/jersey/index.ssf?/base/business-4/116861155665610.xml&storylist=jerseyJan 8 – Japan scientists link strokes to gene varianthttp://www.alertnet.org/thenews/newsdesk/HKG153376.htm Jan 5 – Genetic mutation alters response to heart failure drugshttp://www.sciencedaily.com/releases/2007/01/070102181051.htm Jan 4 – Gender affects genes’ influence on blood pressurehttp://www.reutershealth.com/archive/2007/01/04/eline/links/20070104elin026.html Jan 2 – Genetic mutation alters response to heart failure drugshttp://www.eurekalert.org/pub_releases/2007-01/joci-gma122106.php

Maternal and Child HealthJournal article! Genetic influences on preterm birthhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17205422&dopt=Abstract Jan 3 – Scientists discover how maternal smoking can cause cleft lip and palatehttp://www.nih.gov/news/pr/jan2007/nidcr-03.htmJan 3 – Down syndrome screening recommended for all expectant momshttp://www.app.com/apps/pbcs.dll/article?AID=/20070103/LIFE11/70103008 Dec 28 – Risk of spina bifida associated with choline metabolism genes, but unrelated to choline intakehttp://www.medicalnewstoday.com/medicalnews.php?newsid=59623

Mental HealthA CDC-sponsored evidence report on Testing for CYP450 Polymorphisms in Adults With Non-Psychotic Depression Treated With SSRIs has been released by the Agency for Healthcare Research & Quality (AHRQ).http://www.cdc.gov/genomics/gtesting/EGAPP/docs/announce_2007-01.htm Jan 8 – Genetic variation may reduce Alzheimer’s riskhttp://www.eurekalert.org/pub_releases/2007-01/mcog-gvm010807.php Jan 7 – Researchers looking for genes that control the brainhttp://www.medicalnewstoday.com/medicalnews.php?newsid=60225 Jan 7 – People at genetic risk for Alzheimer’s age mentally just like noncarriershttp://www.eurekalert.org/pub_releases/2007-01/apa-pag010307.php Jan 4 – New report finds little evidence to determine usefulness of genetic tests in treatmenthttp://www.ahrq.gov/news/press/pr2007/cyp450pr.htm

Nutrigenomics

ObesityJournal article! Unraveling the genetics of human obesityhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17196040&dopt=Abstract Jan 8 – Genes, lifestyle raise macular degeneration riskhttp://www.reutershealth.com/archive/2007/01/08/eline/links/20070108elin007.html

Dec 30 – Exercise response varies with genetics – study identifies genes and mutations associated with exercise traitshttp://www.medicalnewstoday.com/medicalnews.php?newsid=59439

PharmacogenomicsJan 12 – Personalizing medicine: Testing how genes affect warfarin dosehttp://www.nj.com/newsflash/jersey/index.ssf?/base/business-4/116861155665610.xml&storylist=jerseyJan 6 – Analysis: Gene tests put docs at riskhttp://www.redorbit.com/news/health/790558/analysis_gene_tests_put_docs_at_risk/index.html Jan 2 – Hazy future for genetic drugs, testshttp://www.mercurynews.com/mld/mercurynews/business/16365391.htm?source=rss

TobaccoJan 8 – Genes, lifestyle raise macular degeneration riskhttp://www.reutershealth.com/archive/2007/01/08/eline/links/20070108elin007.html Jan 3 – Scientists discover how maternal smoking can cause cleft lip and palatehttp://www.nih.gov/news/pr/jan2007/nidcr-03.htm

OtherJan 8 – Genetically altered cells may help artificial skin fight infectionhttp://www.eurekalert.org/pub_releases/2007-01/uoc-gac010307.php Jan 7 – Gene expression speaks as loudly as gene typehttp://www.nature.com/news/2007/070101/full/070101-8.html Jan 2 – NIAID DNA vaccine for HN51 avian influenza enters human trialhttp://www.nih.gov/news/pr/jan2007/niaid-02.htm Dec 28 – A transplant in timehttp://www.eurekalert.org/pub_releases/2006-12/acft-ati122806.php