Autonomic Abnormalities in Patients With Primary Sjogren's ...
Sjogren's Syndrome: The Ulitmate Natural Treatment
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Transcript of Sjogren's Syndrome: The Ulitmate Natural Treatment
SJOGREN’S SYNDROMEthe ultimate
integrative approachAlexander R Shikhman MD PhD FACR
Gluten Free Remedies
SJOGREN’S SYNDROME
SJOGREN’S SYNDROMEkey pathologic mechanisms
• Reactivation of dormant viral infections, such as EBV and CMV• TH1/TH2 imbalance with TH1 predominance• Increased proliferation of Th17 cells• Production of anti-SSA/Ro and anti-SSB/La autoantibodies• Increased production muscarinic M3 receptor antibodies and
correspondent suppression of water channel protein aquaporin-5• Decreased methylation of epithelial cells in exocrine gland
SJOGREN’S SYNDROMEgoals of therapy
• Improve dryness• Normalize autoimmune responses• Prevent malignancies
THE ULTIMATE RECIPE• Improve dryness
SalivaStimBlack Currant Seed OilKrill oil
• Normalize autoimmune responsesArtemisininCordyceps SinensisN-AcetylcysteineI3C/DIMBlack Currant Seed Oil Krill Oil
• Normalize defective methylation of epithelial cells
TMG Plus
• Prevent malignanciesArtemisininI3C/DIMSalivaStim
ARTEMISININ• Inhibition of EBV and CMV• Inhibition of TH1 responses• Inhibition of Th17 responses• Inhibition of B cell proliferation and autoantibody formation
SalivaStim• Increase of water channel aquaporin-5 protein expression• Increase of tear and saliva production
N-ACETYLCYSTEINE • Optimization of TH1/2 and Th17 responses• Antioxidant activity
I3C/DIM• Optimization of Th1/2 response• Protection of salivary and lacrimal glands from the
immunostimulatory effects of estrogens• Anti-viral activity• Protection of epithelial cells lining salivary and lacrimal glands
BLACK CURRANT SEED OIL/KRILL OIL
• Normalization of TH1/TH2 responses• Inhibition of inflammation
CORDYCEPS SINENSIS• Optimization of TH1/TH2 responses• Synergistic effect with Artemisinin
THE DOSAGE REGIMEN• SalivaStim 1000mg in the AM &
500 – 1000mg at 3-4:00pm• Black Currant Seed Oil 2000mg a day• Krill Oil 2000mg a day• Artemisinin 100 mg up to 600mg a day • Cordyceps Sinensis750 – 1500mg in the AM &
at 3 – 4:30pm• N-Acetylcysteine up to 2400mg a day• I3C/DIM up to 1600mg a day • TMG Plus 600-1200mg in the AM
ADJUNCT THERAPYImprovement of intestinal health• Digestive enzymes• Triphala• Probiotics• Prebiotics• Leaky Gut Day,Night, Probiotics
Candida/yeast overgrowth control• Candidacillin• Black Walnut Hulls• Berberine