Sit with people you like to work with, in groups of 3, 4, or 5. Have clickers out.

Georgia Tech School of Biology

Fall 2011Biol 1510

Sit with people you like to work with, in groups of 3, 4, or 5. Have clickers out.

Download Wolfe-Simon et al. paper on arsenic life, and the arsenic life

worksheet


Fall 2011Biol 1510

Arsenic life

Which of the following is NOT one of the six major elements that make up life on earth?a) Hydrogenb) Sulfurc) Phosphorusd) Calciume) Nitrogen


Fall 2011Biol 1510

Arsenic life

What cellular macromolecules contain large amounts of phosphorus?a) Membrane lipidsb) Polysaccharidesc) Nucleic acidsd) Proteinse) All of the above


Fall 2011Biol 1510

Arsenic life

Cells have difficulty distinguishing between arsenic and phosphorus because:a) Arsenic has a similar atomic radius to

phosphorusb) Arsenic has similar electronegativity as

phosphorusc) Arsenic lies immediately below phosphorus in

the periodic tabled) All of the abovee) None of the above


Fall 2011Biol 1510

Periodic table of the elements


Fall 2011Biol 1510

Sit with people you like to work with, in groups of 3, 4, or 5. Have clickers out.

Download Wolfe-Simon et al. paper on arsenic life, and the arsenic life

worksheet


Fall 2011Biol 1510

Fig. 1 Growth and electron microscopy of strain GFAJ-1.

F Wolfe-Simon et al. Science 2011;332:1163-1166

Published by AAAS


Fall 2011Biol 1510

Fig. 2 NanoSIMS analyses of GFAJ-1: extracted DNA and whole-cells elemental ratio maps.


Published by AAAS


Fall 2011Biol 1510

Fig. 3 X-ray analysis of GFAJ-1 +As/–P described similarity of As coordinated like P in DNA. (A) EXAFS comparisons of the Fourier transformed data for As in model environments and

GFAJ-1 (washed and fixed, collected on whole cells).


Published by AAAS


Fall 2011Biol 1510

Arsenic life

Wolfe-Simon et al. showed that in GFAJ-1 cells, most of the radio-labeled arsenic was present in:a) DNA & RNAb) Proteinsc) Lipidsd) A phenol-soluble fractione) An aqueous fraction after organic extraction


Fall 2011Biol 1510

Arsenic life

GFAJ-1 is:a) An extraterrestrial life formb) An obligate arsenophile (needs arsenic for

growth)c) A new species or strain of the Halomonas

genus, known halophilesd) A bacterium that is able to “breathe” arsenate

Sit with people you like to work with, in groups of 3, 4, or 5. Have clickers out.

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