Sex-linked Inheritance. Sex Determination Why are some diseases more common in men than women? ...

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Transcript of Sex-linked Inheritance. Sex Determination Why are some diseases more common in men than women? ...

Page 1: Sex-linked Inheritance. Sex Determination   Why are some diseases more common in men than women?   Ex. Color blind 8 % of males, 8 % of males,

Sex-linked Sex-linked InheritanceInheritance

Page 2: Sex-linked Inheritance. Sex Determination   Why are some diseases more common in men than women?   Ex. Color blind 8 % of males, 8 % of males,
Page 3: Sex-linked Inheritance. Sex Determination   Why are some diseases more common in men than women?   Ex. Color blind 8 % of males, 8 % of males,
Page 4: Sex-linked Inheritance. Sex Determination   Why are some diseases more common in men than women?   Ex. Color blind 8 % of males, 8 % of males,

Sex DeterminationSex Determination

Page 5: Sex-linked Inheritance. Sex Determination   Why are some diseases more common in men than women?   Ex. Color blind 8 % of males, 8 % of males,

Why are some diseases more common in men than women?

Ex. Color blind 8 % of males,8 % of males, but only 0.5% femalesbut only 0.5% females

Page 6: Sex-linked Inheritance. Sex Determination   Why are some diseases more common in men than women?   Ex. Color blind 8 % of males, 8 % of males,

Sex-Linked Traits Sex-Linked Traits Male and Female Male and Female

Page 7: Sex-linked Inheritance. Sex Determination   Why are some diseases more common in men than women?   Ex. Color blind 8 % of males, 8 % of males,
Page 8: Sex-linked Inheritance. Sex Determination   Why are some diseases more common in men than women?   Ex. Color blind 8 % of males, 8 % of males,

Sex-Linked Traits in HumanSex-Linked Traits in Human

Red/Green Red/Green ColorblindnessColorblindness

Hemophilia Hemophilia

Page 9: Sex-linked Inheritance. Sex Determination   Why are some diseases more common in men than women?   Ex. Color blind 8 % of males, 8 % of males,
Page 10: Sex-linked Inheritance. Sex Determination   Why are some diseases more common in men than women?   Ex. Color blind 8 % of males, 8 % of males,
Page 11: Sex-linked Inheritance. Sex Determination   Why are some diseases more common in men than women?   Ex. Color blind 8 % of males, 8 % of males,
Page 12: Sex-linked Inheritance. Sex Determination   Why are some diseases more common in men than women?   Ex. Color blind 8 % of males, 8 % of males,

HemophiliaHemophilia

Page 13: Sex-linked Inheritance. Sex Determination   Why are some diseases more common in men than women?   Ex. Color blind 8 % of males, 8 % of males,

Hemophilia Hemophilia

Queen Victoria of England was a carrier

1819-19011819-1901

Page 14: Sex-linked Inheritance. Sex Determination   Why are some diseases more common in men than women?   Ex. Color blind 8 % of males, 8 % of males,
Page 15: Sex-linked Inheritance. Sex Determination   Why are some diseases more common in men than women?   Ex. Color blind 8 % of males, 8 % of males,

XBXB Normal Female XBXb Carrier Female (normal) XbXb Disorder female

( you need two copies of the gene in females to express)

XBY Normal male XbY Disorder male

Why do you think sex linked traits effect men more than women?

Page 16: Sex-linked Inheritance. Sex Determination   Why are some diseases more common in men than women?   Ex. Color blind 8 % of males, 8 % of males,

Would this person Would this person XXHH X Xhh have have hemophilia? Is this male or hemophilia? Is this male or female?female?

Would person Would person XXHHYY have have hemophilia? Is this male or hemophilia? Is this male or female?female?

Page 17: Sex-linked Inheritance. Sex Determination   Why are some diseases more common in men than women?   Ex. Color blind 8 % of males, 8 % of males,

Sex- Linked Cross Sex- Linked Cross

If a mother who is a carrier for Hemophilia has a child with a father who has normal blood. What percent of the children will have Hemophilia? What percent of the boys?

Page 18: Sex-linked Inheritance. Sex Determination   Why are some diseases more common in men than women?   Ex. Color blind 8 % of males, 8 % of males,

Sex-Linked CrossSex-Linked Cross

Cross a female that has normal vision with a male that is colorblind. What percent of their children will be colorblind?

Page 19: Sex-linked Inheritance. Sex Determination   Why are some diseases more common in men than women?   Ex. Color blind 8 % of males, 8 % of males,

XXBBXXOO- only females can show - only females can show both colors- CALICO both colors- CALICO

Page 20: Sex-linked Inheritance. Sex Determination   Why are some diseases more common in men than women?   Ex. Color blind 8 % of males, 8 % of males,

Problems with Chromosome NumberProblems with Chromosome Number

5.5. Monosomy – only one of a particular type Monosomy – only one of a particular type of chromosome (2n -1)of chromosome (2n -1)

6.6. Trisomy – having three of a particular Trisomy – having three of a particular type of chromosome (2n + 1)type of chromosome (2n + 1)

7.7. Polyploidy – having more than two sets Polyploidy – having more than two sets of chromosomes; triploids (3n = 3 of of chromosomes; triploids (3n = 3 of each type of chromosome), tetraploids each type of chromosome), tetraploids (4n = 4 of each type of chromosome). (4n = 4 of each type of chromosome).