Seminar on Infetion Control

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    SEMINARON

    INFECTION CONTROL

    Presenter

    Ms.Daisy V.T.

    5TH Batch Student

    Guided by

    Dr. Sreedevi T RAsso. Professor

    Govt. College of nursing

    Kottayam.

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    INTRODUCTION Healthcare-associatedinfections (HAIs)area majorcauseof

    morbidityand mortalityaroundthe world.

    Accordingto CDC theincreaseininvasive proceduresanda

    growingresistancetoantibioticshavefuelledariseintherate

    ofHAI by 36% overthe past 20 years.

    Overall 1.4 million people worldwidearesufferingfrom

    nosocomialinfectionsandin Indiaalone,theinfectionrateisatover25 percent,.reportbythe INICC (the InternationalNosocomial Infection Control Consortium )

    Theimportanceofhealthcare-associatedinfections asacause

    ofpreventableillnessanddeath- Aseriousglobal public

    healthissueandanational priority.

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    INFETION CONTROLINFETION CONTROListheresponsibilityofeveryhealthistheresponsibilityofeveryhealth

    Care personnelCare personnel

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    WHAT IS INFECTION?

    The invasion of the body by pathogenic or potentially

    pathogenic organisms and their subsequent multiplicationin the body (Medical dictionary)

    The lodgement and multiplication of parasite in or on the

    tissues of a host.

    ( Anathanarayanan, 2008)

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    Types of infection Primary infection- initialinfection witha parasite

    inthehost

    Reinfection- issubsequentinfectionsbythesame

    parasiteinthehost Secondary infection- anew parasitecausesan

    infectioninahost whoseresistancehasbeen

    loweredbyanalreadyexistinginfectiousdisease.

    Cross infection-anew infectionisestabilshedfromanotherhostorexternalsourceina patientalready

    sufferingfrom adisease

    Nosocomial infection-crossinfectionoccurringin

    hospitals(from Greekword Nosocomion,hospital)

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    Hospital acquired infection(HAI) HAI alsocallednosocomialinfectionisdefinedasan

    infectionoccurringina patientinahospitalorotherhealth

    carefacilityin whom theinfection wasnot presentor

    incubatingatthetimeofadmission

    Italsoincludesinfectionsacquiredinthehospitalbut

    appearingafterdischarge,andoccupationalrelated

    infectionsamongstaffofthefacility(WHO 2002)

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    Historical Perspective

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    Ignaz Semmelweis (1818-1865), the fatherofinfectioncontrol

    demonstrated throughexperimentsthathand-washingcould prevent

    infections.(Conceptofnosocomialinfection wasborn)

    1950s Infection Controlasanorganizedandrecognizeddiscipline was

    born.

    Post World WarII hospital-basedoutbreaksofinfectioncausedby

    Staphylococcus Aureus, mostlyinnewbornnurseries, Outbreaks

    demandedanorganizedresponseforinvestigationandcontrol.

    HISTORY OF NOSOCOMIAL INFECTION

    CONTROL

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    Indian context

    HAIs hasreceivedtheattentionofthe Govt.ofindiaandthe

    Raocommittee,(1968)andthe Sharadkumarcommittee

    (1976) weresetup toinvestigatethe problem ofhospital

    acquiredinfectionsindepth.

    The WorldHealth Organization First GlobalPatient Safety

    Challenge, Clean Careis SaferCare, pledgedtotacklethe

    problem ofhealthcare-associatedinfection waslaunchedin

    2005 . Indiaisthefirstcountryofthe South EastAsian

    Regiontoinauguratethe "Clean Careis SaferCare" initiative

    andsigna pledgetoaddresshealthcare-associatedinfections.

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    MAGNITUDE OF THE PROBLEM

    TheProblem 1.7 million HAIs inhospitalsunknownburdeninother

    healthcaresettings

    99,000 deathsperyear

    $28-33 billion inaddedhealthcarecosts

    HAI Prevention Implementing what weknow forpreventioncanleadtoup

    toa70% ormorereductioninHAIsThe CentersforDisease ControlandPreventionestimates-tenbilliondollarsinadditionalhospitalcostsannuallyasadirectresultofhealthcare-associatedinfections.

    (AHRQS factsheet 2002)

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    HealthyPeople 2020 Phase II

    New TopicAreas

    AccesstoHealth Services

    AdolescentHealth ChildrensHealth

    Genomics

    GlobalHealth

    OlderAdults Healthcare-Associated

    Infections

    QualityofLife

    Social DeterminantsofHealth

    Blood Disordersand

    Blood Safety

    HealthyPlaces Preparedness

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    Nosocomialinfectioncontrolinterventions,

    althoughnotanexplicittargetofthe United

    Nations Millennium Development Goals,

    help support Goal 6 (CombatHIV/AIDS,

    malariaandotherdiseases)

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    AshealthcareAshealthcare

    professionals,itisprofessionals,itisimportanttoimportantto

    understandtwounderstandtwothingsaboutthingsabout

    infectioninfection:

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    1.thevarious waysinfectioncan

    betransmitted

    2.the waystheinfectionchaincanbebroken

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    The Chain of InfectionThe Chain of Infection

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    1 Causative Agent--any disease-causing

    microorganism (pathogen)

    Bacteria

    Viruses

    Fungi

    Parasites

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    RESEARCH EVIDENCE

    .Inadultstudies,E. coli,S. aureus andEnterococcus

    faecalis werethethree mostcommon pathogenscausing

    HAIsinadult patients.

    In pediatric studies,Coagulase negative S. aureus

    (20%26%),Pseudomonas aeruginosa (5%20%),S.

    aureus (11-15%), Candida species (4%9%)and

    viruses, mostlyrotavirusandrespiratorysyncytial virus

    (22%23% ) were predominant pathogenscausing

    HAIs.

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    Characteristics of causative

    agents

    Infective dose

    Pathogenicity

    Virulence

    Invasiveness

    Viability

    Antigenic Variation

    Host Specificity

    Resistance

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    22 -- ReservoirReservoir---theorganism in whichthe

    infectious microbesgrowsormultipliesHumans: Patients and Healthcare

    Workers

    Environment- Patient CareEquipment, Environmental Surfaces

    and Food

    Animals Insects

    Rodents

    Shell Fish

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    3. Portal of Exit

    The route by which theinfectious agent

    leaves the reservoir

    By meansofblood,

    excretions,secretions

    ordropletsfrom brokenskin( puncture,

    cut,surgicalsite,

    weeping wound)

    Respiratorytract Genitourinarytract

    Gastrointestinaltract

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    4 Mode of Transmission

    The mechanism for

    transfer of aninfectious agent from

    the reservoir to a

    susceptible host.

    Contact (Direct and

    Indirect)

    Airborne

    Vector-Borne

    Common Vehicle

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    DIRECT: immediate

    transmission

    Actual physical

    contact between

    source and patient

    INDIRECT

    CONTA

    CT:

    Patient to

    contaminated indirect

    object

    Droplets spread

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    AIRBORNE Organismscontained withindropletnucleior

    dust particles (i.e.dropletnucleioftuberculosis)

    Suspendedinairforextended periods, maybespreadthroughventilationsystems

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    VECTOR-BORN

    Mechanical transfer of microbes on external

    appendages (feet of flies)

    Harbored by vector, but no biological

    interaction between vector and agent (i.e.

    (yellow fever virus)

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    5. PORTAL OF ENTRY

    The route by which aninfectious agent enters

    the susceptible host

    Respiratory Tract

    Genitourinary Tract

    Gastrointestinal Tract

    Broken skin/Mucous

    Membrane

    Blood stream

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    66 -- TheThe SusceptibleHostSusceptibleHost Theorganism thatacceptsthe pathogen.

    Thesupportofpathogenlife & its

    reproductiondependonthedegreeofthe

    hostsresistance.

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    Organisms with strong immuneOrganisms with strong immune

    systems are better able to fend offsystems are better able to fend off

    pathogens.pathogens.

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    Organisms with weakened immuneOrganisms with weakened immune

    systems are more vulnerable to thesystems are more vulnerable to the

    support & reproduction of pathogens.support & reproduction of pathogens.

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    Common HAIs

    Nosocomial Pneumonia

    Surgical site infections

    Catheter associated urinary tractinfections,

    Catheter associated blood stream

    infections.Other nosocomial infections

    Skinandsofttissueinfections:opensores (ulcers,burns

    andbedsores)and Gastroenteritis

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    functionaldisabilityandemotionalstressof

    the patient

    Increased morbidityand mortality

    longerhospitalstays,

    utilize morehealthcareresources

    HAIscontributetoincreasedhealthcare

    costs,

    Impact of nosocomial infections

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    Infection control is the discipline concerned

    with preventing nosocomial or healthcare-associated infection.

    INFECTIONCONTROL-(BREAKING THE

    CHAINOF INFECTION)

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    INFECTIONCONTROL MEASURES

    FORTHE PREVENTION AND CONTROLOF

    HEALTHCARE -ASSOCIATED INFECTIONS

    (Adapted from CDC/WHO guidelines on INFECTION

    CONTROL,2009)

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    1.Hand washing

    2. Standard Precautions in Hospitals3. Transmission based Precautions in Hospitals

    4. Prevention of Ventilator-Associated Pneumonia

    5. Prevention ofSurgical Site Infections

    6. Prevention ofBloodstream Infections

    7. Prevention ofCatheter- AssociatedUrinary Tract

    Infections

    8. Infection Prevention and Control Programs inHospital Settings.

    9. Surveillance and reporting ofHAI

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    Mostnosocomialinfectionsarethoughttobe

    transmittedbythehandsofhealthcare workers

    CDC estimatethatonethirdofallhospital-acquired

    infectionsarecausedbyalackofadherenceto

    establishedinfectioncontrol practices,suchashand

    hygiene.

    CDC recommendshandhygiene (i.e.,hand washingwithsoap and wateroruseofa waterless,alcohol-

    basedhandrub.asthesingle mosteffective method

    ofpreventingthespreadofhealthcare-associated

    infections

    2. Hand Hygiene

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    Research Evidence-

    Sustainedhandhygiene promotionin NICU in

    Genevaresultedina 60% reductioninbacterimia

    among VLBW babies (BorghesiA, 2008)

    Larsonandcolleagues (2000)documentedthat

    the prevalenceofnosocomialinfectionsdecreasedasHCWs compliance withrecommendedhand

    hygiene measuresimproved.

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    New CDC/WHO guideline recommendation for

    hand hygiene in health care settings

    Currentguidelinesrecommendtheuseofalcoholbasedhand

    rubformulationsasthenew standardofcare.

    Theyarenotasubstituteforhand washingifhandsaresoiled.

    Washhand withsoap and waterwheneverthehandare

    visiblysoiledorcontaminated withbloodorbodyfluids.

    Recommendedbeforeenteringtheunit &beforeany

    Procedure Alcoholhand-rubsareappropriateforrapidhand

    decontaminationbetween patientcontacts.

    (WHO GuidelinesonHandHygieneinHealth Care, 2009)

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    HAND WASHING TECHNIQUE Washhandsfor2

    complete minutes

    beforeenteringtheunit

    &beforeany

    Procedure

    Washhandsforatleast

    20 secondsbeforeandaftertouchingeach

    patient

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    Research EvidenceThe choice of the best method of hand hygiene is still a matter of debate

    Larsonetal.foundnostatisticallysignificantdifferencein

    mean microbialcountsonnurseshandsaftertraditionalhand

    washingoralcohol-baseddisinfection

    Ontheotherhand

    Girouetal.observedan 83% reductioninbacterial

    contaminationofthehandsafteruseofalcoholbased

    disinfectantcompared with 58%reductionafterhandwashing

    withantisepticsoap

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    Sarammaetalevaluatedtheeffectof alcoholbased

    handrubbeforeandafterpatientcontacton SSI after

    electiveneurosurgical procedures. Resultdidnot

    show asignificantreductionin SSI compared with

    thecontrolgroup. Studyconcludes withthe

    possibilityisthatboththestrategiesareofequalefficacyforpreventionofSSI

    (Sarammaetal.alcoholbasedhandrubandsurgicalsite

    infection. Neurologyindia.Jan-feb 2011. 59(1).12-17)

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    Adherence withhand washing Studiesrepeatedlydocumentedthatthecompliance with

    recommendedhand washing practicesisunacceptablylow,

    estimatedtobe

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    3.Standard precautions

    STANDARD

    PRECAUTIONS-

    Appliedforall patientsat

    alltimesregardlessof

    theirknownorpresumed

    infectiousstatus

    hand washing and antisepsis

    use of personal protective

    equipment

    appropriate handling of patient

    care equipment and soiled linen

    prevention of needle stick/sharpinjuries

    environmental cleaning and

    spills-management

    appropriate hospital waste

    management.

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    Aseptictechniqueand preventive

    practices Refersto practicestoreducetheriskofpost

    procedureinfectionsin patients-

    measurestodecreasethelikelihoodofmicroorganismsenteringthebodyduring procedures.

    Maintainingcleansterilefieldduring procedures

    Useofsterileinstrumentsandotheritemsforprocedures

    Preparationofthe patientsforclinical procedures

    Useofbarriers ( gown masketc.)

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    Personal protective equipment UsePPE when

    contamination orsplashing with bloodor body fluids isanticipated

    Disposable gloves

    Plastic aprons

    Face masks Safety glasses,

    goggles,

    Head protection

    Foot protection

    Fluid repellentgowns (May, 2000)

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    Appropriatehandlingofpatientcare

    equipment Infectionsfrom used

    instrumentsandother

    items poseinfection

    threatsto patientsand

    healthcare workers.

    Removalof

    microorganism from acontaminatedobjectis

    anessential partof

    infectioncontrol

    Decontamination

    Cleaning

    Sterilization/ highlevel

    disinfection

    Storage

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    Linen handling and disposal

    Gloves and apron - handling contaminatedlinen

    Appropriate laundry bags

    Avoid contamination of clean linen

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    MANAGEMENT OF SHARPS

    correct disposal in a puncture resistantcontainer

    avoid re-capping the needle

    Do not bend, break or cut the needlebefore the disposal.

    Avoid mixing sharps with other wastes discard syringes as single unit

    avoid over-filling sharps container

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    Hospital waste management

    Itisanimportant partofinfectioncontrolinhealth

    carefacilities.

    Itincludessegregation,collection. Transportation

    anddisposal. Hospital wasteincludes

    75-90%non- hazardous( general) waste- donot

    infectthem!!!

    10-25% hazardous waste- takecareofthem.

    Follow hospitalguidelinesbasedongovt.ofIndia-

    Biomedical waste managementguidelines-1998.

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    Additional (transmission-based) precautions

    aretaken whileensuringstandard precautionsare maintained.

    Additional precautionsinclude:

    Airborne precautions; Droplet precautions;and

    Contact precautions.

    4.Additional (transmission-

    based) precautions

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    Implementstandard precautions.

    Place patientinasingleroom withnegativeairflow pressure.

    Keep doorsclosed.

    Anyone whoenterstheroom must wearaspecial,high

    filtration, particulaterespirator(e.g. N 95) mask.

    Makethe patientto wearasurgical maskwhilegoingoutof

    theroom.

    Airborne precautions

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    Implementstandard precautions.

    Place patientinasingleroom (orinaroom withanother

    patientinfectedbythesame pathogen).

    Wearasurgical maskwhen working within 1-2 metersofthe

    patient.

    Placeasurgical maskonthe patientiftransportisnecessary.

    Specialairhandlingandventilationarenotrequiredto

    preventdroplettransmissionofinfection.

    Droplet precautions

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    Implementstandard precautions.

    Place patientinasingleroom (orinaroom withanother

    patientinfectedbythesame pathogen).

    Wearclean,non-sterilegloves whenenteringtheroom.

    Wearaclean,non-sterilegown whenenteringtheroom if

    substantialcontact withthe patient,environmentalsurfacesor

    itemsinthe patientsroom isanticipated.

    Use precautionsto minimizetheriskoftransmissionif

    transportofthe patientfrom theroom isrequired.

    Contact precautions

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    Infectioncontrolrelatedtocommonhospital

    acquiredinfections

    Nosocomial Pneumonia

    Surgical site infections Catheter associated urinary tract

    infections,

    Catheter associated blood streaminfections

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    Ageappropriatecomprehensive mouthcare.

    Dailyassessmentforextubationreadiness.

    Intubationandreintubationshouldbeavoided

    Preventventilatorcircuitcondensation

    Keep the patientin semirecumbent position (3045)foradultsand 15-

    30 degreeforchildrento preventaspiration,especially whenreceiving

    enteralfeeding.

    Suctionaboveandbelow thecuffbeforeloweringthe patientsheadless

    thanto 30% to prevent microaspiration.

    Theendotrachealtubeshouldbeofpropersizeto preventleakageof

    bacterial atho ensaroundthecuffintothelowerres irator tract.

    Prevention of Ventilator Associated

    Pneumonia

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    identifyandtreatallinfectionsremotetothesurgicalsitebefore

    electiveoperation

    Donotremovehairpreoperativelyhairmaybeclippedshortifit

    interferesthe procedure. Useanappropriateantisepticagentforskin preparation.

    Keep preoperativehospitalstayasshortas possible

    Anti microbial prophylaxis

    Intra operative Ventilation

    Maintain positive-pressureventilationintheoperatingroom.

    Maintaina minimum of15 airchanges perhour,ofwhichatleast 3

    shouldbefreshair.

    Cleaning and disinfection of environmental surfaces

    7.Prevention ofSurgical Site Infections

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    Airandenvironment

    Laminarairflow-designto move particlefreeair( ultralean

    air).

    Operatingroom equipmentandfurnitureshouldbecleaned

    withgermicidalagentattheendofeachsurgical procedure.

    Lidwelletal.comparedtheeffectofultracleanairalone,

    antimicrobial prophylaxisaloneandcombinationofbothin

    prosthesisreplacement. Resultsshownantimirobials more

    effectivethanultracleanair. (JHosp Infect, 1988)

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    Unexpectedlyinone analysis whichcontrolledformany

    patients ORventilation withlaminarairflow showednobenefiton SSI.( Brandt C Ann Surg. 2008Nov, 248(5). 695-700.)

    Withoutsurgicalantimicrobial prophylaxis,glove perforation

    increasestheriskofSSI (Heidi M etal.Arhivesofsurgery.June 2009,144(6). 553.)

    Postoperative Incision Care

    Perform handhygienebeforeandafterdressingchanges

    andanycontact withthesurgicalsite.

    Whenanincisiondressing mustbechanged,usesteriletechnique.

    Educatethe patientandfamilyregarding properincision

    care,symptomsofSSI,andtheneedtoreportsuch

    symptoms.

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    Hand hygieneAseptic technique during catheter insertion and care

    Catheter insertion

    Donotroutinelyusearterialorvenouscutdown procedures

    asa methodtoinsertcatheters.Catheter-site dressing regimens

    - Useeithersterilegauzeorsterile,transparent,semi

    permeabledressingtocoverthecathetersite.

    -Gauzedressingsthat preventvisualizationoftheinsertionsiteshouldbechangedroutinelyevery48 hoursoncentral

    sitesandimmediatelyiftheintegrityofthedressingis

    compromised.

    -Replacecatheter-sitedressingifthedressingbecomes

    dam loo ened orvi ibl oiled.

    8.Prevention ofBloodstream Infections

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    Catheter removal

    -Promptlyremoveanyintravascularcatheterthatisno

    longeressential.

    - Donotroutinelyreplacecentralvenousorarterial

    catheterssolelyforthe purposesofreducingtheincidenceof

    infection.

    - Replace peripheralvenouscatheters every 7296 hoursinadultsto prevent phlebitis.

    - Leave peripheralvenouscathetersin placeinchildren

    until IV therapyiscompleted,unlesscomplications (e.g.,

    phlebitisandinfiltration)occur.

    AstudyinthejournalInfection Control andHospital Epidemiology shows

    thatabout 24% ofpatients withcatheters willdevelop catheterrelated

    infections,ofwhich 5.2% willbecomebloodstream infections. Deathhas

    beenshowntooccurin420% ofcatheter-relatedinfections.

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    Prevention ofCatheter-Associated

    Urinary Tract InfectionsBurden ofCAUTIs

    Urinarytractinfectionisthe mostcommonhospitalacquired

    infection; 80% oftheseinfectionsareattributabletoan

    indwellingurethralcatheter.

    Risk factors for development ofCAUTI

    Thedurationofcatheterization- mostimportantriskfactor

    Limitingcatheteruseand, whenacatheterisindicated,

    minimizingthedurationthecatheterremainsinsituareprimarystrategiesforCAUTI prevention.

    Ensureaseptictechniqueduringcatheterinsertion

    Ensurethattrained personnelinserturinarycatheters.

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    Reservoir for transmission

    Thedrainagebagofthebacteriuric patientisareservoirfor

    organismsthat maycontaminatetheenvironmentandbe

    transmittedtootherpatients.

    Willson M etalidentifiedthefollowing nursing

    interventions to reduce the risk of catheter-associated

    urinary tract infection:

    staffeducation, monitoringofcatheteruseand CAUTI

    incidence,insertiontechnique,urethral meatalcare,

    securement,useofacloseddrainagesystem,bladder

    irrigation,frequencyofcatheterchange,andantisepticsolutionsinthedrainagebag.

    J Wound Ostomy Continence Nurs. 2009 Mar-Apr;36(2):137-54.

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    Representativesofvariousunits withinthehospital (medical,nursing,

    engineering,housekeeping,administrative, pharmacy,sterilizingservice

    and microbiologydepartments);

    Developmentofpoliciesforthe preventionandcontrolofinfectionandto

    overseetheimplementationoftheinfectioncontrol programme

    develop itsowninfectioncontrol manual/s;and

    monitorandevaluatethe performanceoftheinfectioncontrol programme.

    The infection control committee

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    Responsiblefortheday-to-dayactivitiesoftheinfectioncontrol

    programme.

    supportand participateinresearchandassessment programmesat

    thenationalandinternationallevels.

    carryoutthesurveillance programme;

    develop anddisseminateinfectioncontrol policies;

    monitorand managecriticalincidents;

    coordinateandconducttrainingactivities.

    Infection control team

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    Hospital-associatedinfectioncontrol

    instructionsand practicesforpatientcare.

    The manualshouldbedevelopedandupdatedbytheinfectioncontrolteam andreviewed

    andapprovedbythecommittee.

    Readilyavailableforhealthcare workers,andupdatedinatimelyfashion.

    Infection control manual

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    SurveillanceandreportingofHAI Surveillanceisthe monitoringofinfectionsin

    theunitbyconducting periodicsurveysto

    detectandrecord methodicallyallHAIs. Continuoussurveillanceallowstheearly

    identificationofoutbreaks.

    Agoodsurveillance practiceisanimportantaspectofinfectioncontrol.

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    Nursingimplications

    Nurses are the key to maintain infection controlmeasures in health care settings

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    Roleofthe Infection Control NurseNeedtohave highdegreeofawarenessandknowledge ininfection

    control

    Researchindicatesa positiverelationshipbetweenknowledgeand

    practice. (VijiAetal, 2007)

    Collectandcoordinateinformationregardinghospitalinfections

    from variousclinicaldepartments

    Conductsin-serviceeducation,refreshercoursesandtraining

    programmesoninfectioncontrol.

    Continuesvigilance,assessmentandsupervisionofclinicalperformanceofvariouslevelsofworkers.

    ContinuessurveillanceforHAI.

    Conductsawarenessamongthe patientsandvisitorsaboutinfection

    control

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    CONCLUSION PreventingHealthcare-associated Infections

    the Timeis NOW

    Problem iscriticalandcostlybut preventable Interventionscanhaveanimmediatenational

    impact

    Interventionscanbecostsavings Ongoingeffortsareneededtoaddress

    changesinhealthcare

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    Infectioncontrolisnotjusta matterof

    followingstandardsandguidelines. It

    involvesimprovingawarenessandchangingattitudesand workpracticesatboththe

    institutionalandindividuallevel. Itis

    essentialthateveryoneinvolvedinhealthcare

    contributetoimprovingthequalityofpatient

    care (NHMRC, 1996).

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    Thought for infection control It is not important how much you know but it is

    most important how much you practice.

    Caring attitude should be reflected in your workpractice, which will reflect your infectioncontrol practices.

    If you fail to practice infection control,you are failing to care for your patients.

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