SCTR Pilot Project Program - South Carolina Clinical and ... · PDF fileSCTR Pilot Project...
Transcript of SCTR Pilot Project Program - South Carolina Clinical and ... · PDF fileSCTR Pilot Project...
SCTR Pilot Project Program
Perry V. Halushka, PhD. MD -‐ Director Tony Alberg, PhD -‐ Associate Director
Randal Davis – Project Director Dayan Ranwala, PhD -‐ Science Program Manager
Patrick Flume, MD – Chairman, ScienFfic Review CommiHee
https://sctr.musc.edu/index.php/programs/pilot-projects
sctr.musc.edu 843-792-8300
Pilot Project Program Overview
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• To facilitate new & innovaFve clinical & translaFonal research • To promote scienFfic interacFons among invesFgators & community • To accelerate processes from discovery, innovaFon to improved
paFent care • To provide research support for promising trainees/junior faculty • To support development of new technologies & methodologies
Pilot Project Program Expectations
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• Proof-‐of-‐concept studies, clinical applicability and disseminaFon • GeneraFon of cri%cal preliminary data • Successful applicaFons of extramural grant funding mechanisms • Successful publica%ons of research data & findings • Development of potenFal Intellectual Property (IP) and
commercializaFon of technologies
Pilot Project Program RFA
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Ins%tu%onal Funds:
• MUSC -‐ $500K/year • USC -‐ $200K/year
Grant Categories (all awards are for 12 months):
• Discovery Grants (up to $25K) • Fast-‐Forward Seed Grants (up to $10K*) • High InnovaFon – High Reward Grants (up to $10K)
*Requires 1:1 Match -‐ $5K SCTR funds, $5K matching funds
Pilot Project Grant Categories
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• Discovery Grants § Two cycles per year § Pre-‐applicaFon is required, due by noon on 11/15 § Selected pre-‐applicants will be invited to submit full applicaFons
• Fast Forward Seed Grants § Three cycles per year § No pre-‐applicaFon process, full applicaFon due by noon on 8/16 § Limited to resubmission of extramural grant applicaFons § Requires 1:1 match as new money (not from exisFng grants/
salaries) § Requires to provide the source and amount of the match
Pilot Project Grant Categories
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• High Innova%on – High Reward Grants § Three cycles per year § No pre-‐applicaFon process § Limited to MUSC PIs leading to substanFal development of IP for high
reward. § SCTR & CIE will provide consultaFons as needed related to IP and
commercializaFon. PIs may want to request a consult before applying.
§ Successful projects will be invited to submit a LeHer of Intent (LOI) to Center for InnovaFon and Entrepreneurship (CIE) for a high reward grant ~200-‐500K
§ CIE Director: Tom Finnegan § Technology Development Officer: Jessie Goodwin, PhD
Pilot Project Application Process
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• Apply online via SCTR Pilot Project web page using the ‘Apply’ link • Required Components:
§ PI and invesFgator team informaFon § File uploads based on grant category (page limitaFons)
Ø Each invesFgator biosketch Ø Project DescripFon Ø Research proposal* Ø Budget and jusFficaFon (not required for Discovery pre-‐apps, two
budget forms required for Fast Forward Seed (FFS) apps due to the matching fund requirement)
Ø Matching fund commitment leHer required for FFS apps
Discovery Pre-application Proposal
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• One page (two pages allowed only for EC inves%gators): • One page must include:
§ Research design and methods § BiostaFcal jusFficaFon for the sample size* § Brief descripFon of the mulFdisciplinary team § Each team members role § PotenFal for extramural grant funding
*ApplicaFons will be reviewed by a biostaFsFcian. ApplicaFons must be adequately powered to provide meaningful informaFon about the feasibility and size for your planned future studies to apply for extramural grant applicaFons.
Note: SCTR provides free biostat consulta8ons if needed
Discovery Pre-application Proposal
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• Early Career inves%gators must include below in the second page*: § a perFnent senior Co-‐InvesFgator(s) as mentor(s) and include the
mentor/s name and their support leHer/s at the end of the proposal § a strong mentorship plan § a Fmetable for becoming independent and a plan for achieving
research independence § potenFal to lead to independent funding (with a plan to submit K or R
applicaFons) NOTE: Please carefully read ‘Review Criteria for Scoring’ giving especial a?en8on to the ‘Inves8gator(s)’ criteria in order to properly submit an early career applica8on.
*Applica8ons will be reviewed for these criteria.
Discovery Pre-application Proposal
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• Novel Methods/Technology Core Facility Development related applica%ons must include*: • potenFal value to mulFple invesFgators facilitaFng clinical &
translaFonal research and supporFng extramurally-‐funded research projects
• an adequate business plan and cost effecFveness of allowing mulFple invesFgators to use
NOTE: Please carefully read ‘Review Criteria for Scoring’ giving especial a?en8on to the ‘Innova8on’ criteria.
*Applica8ons will be reviewed for these criteria.
Pilot Project Review Process
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• Budget: Refer to RFA for details • Review Process:
§ Similar to a NIH study secFon § Review based on the core criteria, Significance including scienFfic merit of the proposal is the most important factor
§ ScienFfic Review CommiHee (SRC) – scienFfic review § ExecuFve CommiHee – funding decisions
• No%fica%ons: Review comments will be sent to the PIs except for the pre-‐ applicaFons For funded projects JIT & NOA will be sent to PIs
• Progress Reports: Required at 6 and 12 months, and yearly for 5 years
Scientific Retreats
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Goal: To sFmulate new mulFdisciplinary research teams and research projects by bringing together researchers from different disciplines around a cross-‐cuhng scienFfic theme. Frequency: 2 scienFfic retreats/year Approach: Themes are prioriFzed based on whether the topic:
• is cross-‐cuhng with a large enough criFcal mass of local invesFgators
• addresses unmet medical needs • is a significant burden in South Carolina and beyond • will generate use of novel technologies
Scientific Retreat Format
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• Na%onally renowned external keynote speaker: § What are the key issues facing the field?
• 3-‐4 plaZorm presenta%ons: What are the local opportuni%es? § Local experts, different disciplines § Briefly describe personal research interest § Future research topic that requires new collaboraFons
• 30 minute “speed da%ng” session: Facilitate interac%on § Generate new interacFons and new ideas
• Conclude: Encourage pilot project applica%ons § Overview of SCTR Pilot Project Program and how to apply
• Pilot funds set aside for a`endees on the retreat theme
Pilot Project Program Contact
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Dayan Ranwala, PhD [email protected] or 843-‐792-‐1498
sctr.musc.edu
h`ps://sctr.musc.edu/index.php/programs/pilot-‐projects
Request a consultaFon at: sparc.musc.edu
SCTR Vouchers
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• Open to MUSC PIs only • Vouchers up to $1,000 are available for services and supplies
for research projects • Lab services, clinical procedures, core facility services, etc.
• Only 1 voucher is allowed per protocol annually • A PI is limited to 1 voucher per year • Vouchers expire one year from the date of approval • Most vouchers approved within 24-‐48 hours • Apply for a voucher via SPARC Request: sparc.musc.edu
SCTR Acknowledgment
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Please remember to acknowledge NIH/NCATS
SCTR Grant Number
UL1 TR000062
Announcements
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• Request Proposals for ScienFfic Retreats • Join the SCTR Listserv (email [email protected]) • Have quesFons, need help/consultaFons, contact SCTR at:
• via SPARC at sparc.musc.edu • Call 843-‐792-‐8300 • Email at [email protected]