SALES OFFICES - Waters Corporation · 2015-01-22 · [ COURSE CATALOG – EUROPE 2015-2016 ]...

[ COURSE CATALOG – EUROPE 2015-2016 ]

Waters, The Science of What’s Possible,ACQUITY, ACQUITY UltraPerformance LC, ACQUITY UPC2, ACQUITY UPLC, Alliance, Connections INSIGHT, Empower, HDI, HDMS, High Definition, MassLynx, Micromass, Millennium, NANOACQUITY, NuGenesis, QDa, UltraPerformance LC, UNIFI, UPC2, UPLC, Waters Quality Parts, and Xevo are trademarks of Waters Corporation. ApexTrack, AutoPurification, AutoPurify, Baseline, BiopharmaLynx, ChromaLynx, ChromScope , DriftScope , eCord, eLab Notebook Proteomics, FractionLynx, IntelliStart, iRequest, LAC/E, LockSpray, MALDI SYNAPT, MarkerLynx, MassFragment, MaxEnt, MetaboLynx, NanoFlow, NanoLockSpray, NeoLynx, OpenLynx, ProteinLynx Global SERVER , Q-Tof, QuanLynx, QuanOptimize, QUANPEDIA, SDMS Vision Publisher, SystemsQT, TargetLynx, UltraPerformance Convergence Chromatography, UltraPerformance SFC are trademarks of the Waters Corporation. All other trademarks are the property of their respective owners.

©2015 Waters Corporation. Printed in the France January 2015 720001070EN AW-CP-IH

CHOOSE WATERS EDUCATIONAL SERVICES

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SALES OFFICES

Austria 43 1 877 18 07

Belgium and Luxembourg 32 2 726 1000

Czech Republic 420 2 617 11384

Denmark 45 46 59 8080

Finland 358 9 5659 6288

France 33 1 30 48 72 00

Germany 49 6196 400 600

Hungary 36 1 350 5086

Ireland 353 1 448 1500

Italy 39 02 265 0983

The Netherlands 31 76 508 7200

Norway 47 6 384 6050

Poland 48 22 101 5900

Russia/CIS 495 727 4490 / 290 9737

Spain 34 93 600 9300

Sweden 46 8 555 115 00

Switzerland 41 56 676 7000

United Kingdom 44 208 238 6100

FOR REGISTRATION, LOCATION, FURTHER DETAILS, PLEASE VISIT OUR W EBISTE

W W W.WATERS.COM/COURSES

Waters Corporation European Headquarters and Training Center BP 60878056 Saint-Quentin-en-Yvelines, France

Phone 33 1 30 48 72 00Fax 33 1 30 48 72 01

Waters MS Technology Centre Waters GmbHMicromass Atlas Park, Simons Way Europaallee 27–29Manchester, M22 5PP, United Kingdom 50226 Frechen, Germany

Phone 44 161 435 4100 Phone 49 2234 9207 0Fax 44 161 435 4444 Fax 49 2234 9207 99

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Self-Paced e-Learning

Anywhere and at your convenience

Benefitsn Learn at your own pace and convenience,

right at your computer

n Save time and eliminate travel costs

n Evaluate your progress with skill assessments

n Reduce learning time by focusing only on the areas you need

n Receive proof of training for your records

...And still get the quality training prepared by Waters trainers

To learn more, go to page 125 or visit

www.waters.com/elearning

Do you need training at a convenient time or location?

Do you have an employee who missed on-site training?

Do you need a training refresher?

If you answered yes to any of these questions, then a Waters® Self-Paced e-Learning session may be the solution for you.

Self-Paced e-Learning training available in:n HPLC, UPLC®, LC-MS (Theory, Operation, Maintenance)

n Empower® 3, MassLynx®, and UNIFI Software

n Small and large molecule applications

n Recertification exams for Waters SystemsQT™ Qualification Tool

And More…

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One stop shopping for all your training needs.

Logon to our training site for:n Training courses, descriptions, and fees

n Latest course schedules

n Special offers and discounts

n Easy course registration

n And much more

Everything you need – from one single source.

Visit www.waters.com/courses and bookmark it today.

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*Laboratory Informatics Empower Software courses are appropriate for Empower, Empower 2, and Empower 3 Software users.

LABORATORY INFORMATICS EMPOWER*What’s New in Empower 3 Software? 09Empower Fundamentals of the QuickStart Interface 10Empower QuickStart Interface with Lab 11Empower Software: Advanced Topics 12Empower Software: Advanced Topics: Acquisition, Processing and Reviewing Results 13Empower Software: Advanced Topics: Custom Fields and Reports 14Empower Software: Advanced Topics: using Administrative Features for Productivity 15Empower 2/3 Software: Advanced Topics with Lab 16Empower Software: Enterprise System Administration and Maintenance 17Empower Software: Enterprise Database Administration and Maintenance 18Empower Software: Fundamentals using the Pro Interface 19Empower Software: Method Validation Manager 20Empower Software: Self-use of SQT software 21Empower Software: using the Software in a Regulated/Audited Environment 22Empower Software: using the GPC option with the Pro Interface 23Empower Software: using the Pro Interface 24Empower Toolkit 25Using the Photodiode Array (PDA) Detector with Empower Software 26Empower Data School initiation 2D 27Empower Data School initiation 3D 28Empower Data School Advanced 2D 29Empower Data School Advanced 3D 30

LABORATORY INFORMATICS MASSLYNXBiopharmaLynx 32ChromaLynx XS 33MarkerLynx XS 34MassLynx Data School 35MassLynx Data School 2D 36MetaboLynx XS 37Open Access Login Application Manager 38OpenLynx Software 39QuanLynx and TargetLynx Application Manager 40

LABORATORY INFORMATICS NUGENESISNuGenesis SDMS System Administration 42NuGenesis SDMS and SDMS Vision Publisher Software Development Kit 43NuGenesis 8 Lab Execution Method Editor 44NuGenesis 8 ELN Administrator 45NuGenesis 8 Advance System Administration and Infrastructure 46NuGenesis 8 SDMS Administration 47SDMS Vision Publisher/eLab Notebook System Administration 48

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[ TABLE OF CONTENTS ]

ULTRAPERFORMANCE LC (UPLC) TECHNOLOGYACQUITY UPLC for Laboratory Practitioners 52ACQUITY UPLC Maintenance 53ACQUITY UPLC School with Empower 54ACQUITY UPLC School for the Lab Practitioner 55ACQUITY UPLC H-Class and ACQUITY UPLC H-Class Bio System for Lab Practitioners 56Maintaining the ACQUITY UPLC H-Class and ACQUITY UPLC H-Class Bio System 57Operation of ACQUITY UPLC Systems (Classic, H-Class & I-Class) 58ACQUITY UPLC I-Class Maintenance 59ACQUITY UPC2 for Laboratory Practitioners 60Maintaining ACQUITY UPC2 61Using ACQUITY QDa with Empower 62

OPERATION AND MAINTENANCEAlliance 2695 Operation and Diagnostics 66Alliance 2695/2795 Operation and Maintenance 67Alliance 2795 System Operation and Maintenance 68Maintenance School – 717Plus automatic injector 69Maintenance School – Detection System 70Maintenance School – Pumping System 71Qualification School LC System 72Troubleshooting and Maintenance of HPLC Systems 73

MASS SPECTROMETRYACQUITY QDa with Empower 76Characterization of Peptides and Proteins by LC-MS/MS 77Fundamentals of LC-MS 78Interpretation of MS and MS/MS Spectra 79LC-MS/MS School 80MALDI SYNAPT G2-S HDMS 81MALDI IMAGING Operation 82LC-MS Course at Waters facilities 83nanoACQUITY UPLC Techniques and Operation 84Purification of Compounds using FractionLynx (Mass Detector) 85Purification of Compounds using FractionLynx (UV) 86Quantification of Peptides and Proteins by LC-MS/MS 87SYNAPT G2-Si (Biopharmaceutical) 88SYNAPT G2-Si (NanoFlow Proteomics) 89SYNAPT G2-Si (Small Molecules) 90

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Xevo G2-XS Tof/Q-Tof (Biopharmaceutical) 91Xevo G2-XS Tof/Q-Tof (NanoFlow Proteomics) 92Xevo G2-XS Tof/Q-Tof (Small Molecules) 93Xevo G2-XS Tof/Q-Tof UNIFI (Biopharmaceutical) 94Xevo G2-XS Tof/Q-Tof UNIFI (Small molecules) 95Xevo TQD Operation and Maintenance 96Xevo TQ-S Operation and Maintenance (NanoFlow Proteomics) 97Xevo TQ-S and Xevo TQ-S micro 98Xevo TQ-S Micro Operation and Maintenance 99Xevo TQ-S UNIFI (Bioanalysis) 100

GENERAL CHROMATOGRAPHYHPLC Fundamentals and Troubleshooting 104Concepts of Sample Preparation with SPE (Solid-Phase Extraction) 105Fundamentals of HPLC 106Fundamentals of HPLC (Theory) 107HPLC Method Development 108HPLC Method Development (Theory) 109HPLC Troubleshooting and Disfunctionning Diagnosis 110Practical Method Development with Lab 111Principles and Practices in HPLC 112Troubleshooting Common HPLC Problems 113

SUPERCRITICAL FLUID CHROMATROGRAPHY (SFC)Introduction to SFC 116SFC Purification with ChromScope 117SFC Purification with FractionLynx 118ACQUITY UPC2 for Lab Practitioners 119Maintaining ACQUITY UPC2 120

ON-SITE EDUCATION 123

eLEARNING 126

REGISTER TODAY 132

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BE ASSUREDChoose Waters Global Services

Advance the Business of Science with Empower Driven Services Optimize laboratory resources through continuous improvement and life cycle asset management. Empower Driven Services integrates instrument services and the business analytics managed by Empower Software to uncover efficiencies and cost savings.

➜ Learn more at www.waters.com/empowerdriven

Protect Your System Investment Only the worldwide Waters service team has the knowledge, experience, and technical and application support to ensure that your mission-critical system operates with optimum productivity and lowest total cost-of-ownership.

➜ Learn more at www.waters.com/plans

Enhance Performance; Extend System LifetimeWaters offers a range of instrument upgrades that give you access to the latest technologies to improve instrument control and data acquisition functions, increase productivity, and extend system lifetime.

➜ Learn more at www.waters.com/upgrades

Services for Agilent SystemsWaters has expanded its competencies in supporting Agilent LC and GC systems by providing same quality control processes, parts supplies, and operational infrastructures you experience with Waters systems. Call your local office today to find out how we can help you consolidate all your service contracts for Waters and Agilent Systems.

Keep Your Laboratory Skills up to DateFrom instrumentation operation and maintenance, to applications and information management solutions, whether you are a new or an experienced user, Waters has a course for you.

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One-Click, Online Access to Waters Service TeamsRequesting phone support, onsite service, and training for your Waters instruments and software has never been easier with iRequest™ Online Service Request System.

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Optimize Qualification Efficiency. Ensure Full ComplianceUsing automated compliance tools as well as conventional qualification workbooks and testing materials, trained and certified Waters Compliance Service Specialists use proven procedures and technologies to help you integrate or maintain LC or MS systems and software into your regulated laboratory.

➜ Learn more at www.waters.com/compliance

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[ LABORATORY INFORMATICS ] EMPOWER

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Empower Driven Services

Advancing Your BusinessEmpower Driven Services integrate instrument services and laboratory analytics, enabling organizations like yours to optimize resources through continuous improvement and superior lifecycle asset management.

Determine if resources are being deployed effectively to meet the needs of your business and how to change that deployment as needs change. With Empower Driven Services you can: n Uncover new areas of cost savings

n Maximize the efficiency of existing assets

n Optimize workflow processes

n Justify new technology adoption

n Integrate with Lean 6 Sigma Initiatives

For more information, go to

www.waters.com/empowerdriven

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What’s New in Empower 3 Software?

Language: German Location: Austria, Switzerland

Ref.: 750000567 – 1 day

Course DescriptionT his course shows how to use many features of Empower Chromatography Software. T he emphasis is on organizing,acquiring, processing, and reporting chromatography data. This instructor-led hands-on computer course is for experiencedEmpower Chromatography Software users.

Topics Covered ❱ On-line registration for license activation ❱ Empower 3 Software help and search information ❱ eCord™ Data in Empower Configuration Manager ❱ Process only sample sets ❱ ApexTrack™ changes ❱ Third Party instrument control additions and changes ❱ Empower 3 Software help resources ❱ Configuration manager changes ❱ User perspective on system policies and privileges ❱ User accounts, user types, user groups, group administrator ❱ Mass Spec enhancements ❱ Organizing and accessing information in Empower ❱ Developing a processing method manually in review ❱ ApexTrack integration ❱ System suitability enhancements ❱ Altering samples and batch/background processing ❱ Reviewing results and calibration curves ❱ Creating reports – individual and summary report methods ❱ Customizing headers and footers with logos and special information ❱ Using Empower Software to generate reports for methods

Who Should AttendThis course provides a hands-on introduction to the new features and enhancements offered in Empower 3 ChromatographySoftware. T he topics are for experienced users who want to access the flexibility built into Empower and their use of thesoftware to meet individual lab application needs. If you are an experienced Empower user, this instructor-led training coursecombined with hands-on computer use is the right course for you.

PrerequisitesAttendees must have at least one year experience using Empower Software. Familiarity with the Pro Interface is helpful.

Course NotesEach attendee receives a course manual for reference and will receive a Certificate of Attendance. This course uses Empower Software and the Pro Interface.

9For further information and registration, visit www.waters.com/courses

[ LABORATORY INFORMATICS ]

Who Should AttendThis course is for new users of Empower Software who want to rapidly learn to use the QuickStart interface.

PrerequisitesNone.

Course NotesEach attendee receives a course manual for reference and will receive a Certificate of Attendance.

Topics Covered: ❱ Overview and login •Empower terminology •Overview of the QuickStart interface •Creating an instrument method and method set •Collecting data •Creating a simple sample set •Running a sample set •Creating a sample set method •Developing a processing method •Overview of the review window •Creating a processing method using the wizard •Understanding and optimizing integration parameters •The component table •Adding a processing method to the method set

❱ Finding information •Using view filters •Sorting data in columns •Using the “view as” function

❱ Alter sample, batch processing and reviewing results •Changing sample information •Batch processing a sample set

❱ Reviewing results •Manually adjusting integration •Manually identifying peaks •Reviewing the calibration curve

❱ Reporting •Using and modifying a default report method •Adding a report method to the method set

❱ Managing projects, systems and user accounts •Creating a project •Backup and restore a project •Copy data •Change project/system •Manage the user account

Empower Software Fundamentals of the QuickStart Interface

Language: Danish, English, Finnish, German, SwedishLocation: Denmark, Finland, Germany, Ireland, Norway, Sweden, Switzerland, United Kingdom

Ref.: 750000634 – 1 day

Course DescriptionThe Empower Software Fundamentals of the QuickStart Interface course demonstrates how to efficiently collect chromatography data and generate results using Empower Software with the QuickStart interface.

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Empower Software Quickstart Interface with Lab

Language: Dutch, French, SpanishLocation: Belgium, The Netherlands, Spain

Ref.: 750000580 (Empower 3) – 2 days

Course DescriptionThis 2-day course shows how to efficiently collect, integrate, calibrate, quantitate and report chromatography data using Empower Chromatography Software via the QuickStart Interface. The attendee uses the software throughout the entire course. The instructor led segments and the practice exercises reinforce the skills needed for success.

Topics Covered:Utilization of the QuickStart Interface for acquisition, processing and using existing reports

❱ Create instrument methods, method sets and sample set methods to run samples ❱ Develop processing methods ❱ Alter sample information ❱ Batch/background processing ❱ Find information ❱ Review results and calibration curves ❱ Modify existing report methods ❱ Summary exercise (optional)

Who Should AttendThis course is for new users of Empower Software who want to rapidly learn to use the QuickStart Interface.

PrerequisitesNone.

Course NotesEach attendee receives a course manual for reference during and following the course and will receive a Certificate ofAttendance. This course uses only Empower Software and the QuickStart Interface.



Empower Software Advanced Topics

Language: English, ItalianLocation: Ireland, Italy, United Kingdom

750000569 (Empower 3) – 3 days

Course DescriptionThis intensive 3-day course shows how to use many advanced features of Empower Chromatography Software. The emphasis is on organising, acquiring, processing, and reporting chromatographic data. Additional topics include adding custom sample descriptions and creating custom calculations for chromatographic data. This instructor-led hands-on computer course is for experienced Empower and Millennium®32 Chromatography Software users.

Topics CoveredThe Pro interface for organizing information, acquiring and processing data, and creating custom fields and reports

❱ Daily events ❱ Login window properties ❱ The user perspective on system policies and privileges ❱ Understanding the effects of system policies ❱ Default strings ❱ User accounts, user types, user groups, group

administrator ❱ Acquisition servers and chromatographic systems ❱ Cloning projects and multi-project searching ❱ Organizing and accessing information in Empower ❱ Creating view filters ❱ Using just-in-time view filters ❱ Comparing method versions ❱ Lock/unlock channels ❱ Creating a sample set method template ❱ Developing a processing method manually in review ❱ Traditional vs. ApexTrack detection and integration

theory ❱ Global peak detection parameters ❱ Using integration events ❱ Noise and drift calculations in Empower ❱ System suitability ❱ Altering sample information and batch/background

processing ❱ Reviewing results and calibration curves ❱ Adding points, ignoring points ❱ Saving calibration curves, using an earlier calibration

curve, recalculating results

❱ Troubleshooting calibration curves ❱ Creating custom fields ❱ Adding sample identifiers using the keyboard or

selection from a list you create for data entry ❱ Adding component specific numerical information ❱ Calculations with peaks ❱ Boolean calculations with peaks ❱ Using text strings as the output for peak calculations ❱ Inter-sample calculations ❱ Creating custom reports- individual and summary

report methods ❱ Customizing headers and footers with logos and

special information ❱ Using Empower to generate reports for methods ❱ Using data filters ❱ Creating composite groups ❱ Summarizing statistical information for replicate

injects of one standard ❱ Using overlay chromatograms and ordering tables ❱ Summarizing statistical information for replicate

injections of multiple standards ❱ Using composite groups to associate and order

chromatograms and tables ❱ Summarizing component information for all results

in a result set ❱ Arranging chromatograms and tables next to each

other on the report page

Who Should AttendThis course is for users who know Empower Software software fundamentals and seek fast-paced, intensive training on advanced features using the Pro Interface. The topics are for experienced users who want to access the flexibility built into Empower and customize their use of the software to meet individual lab application needs. If you are an experienced Empower user, this instructor-led training course combined with hands-on computer use is the right course for you.

PrerequisitesAttendees must have at least four months experience using Empower Software. Attending the Empower Software Essentials of the QuickStart interface course is strongly recommended. Familiarity with the Pro Interface is helpful.


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Empower Software Advanced Topics: Acquisition, Processing and Reviewing Results

Language: Danish, Dutch, English, French, German, Italian, Spanish, SwedishLocation: Belgium, Denmark, Finland, Germany, Ireland, Italy, The Netherlands, Norway, Spain, Sweden, Switzerland

Ref.: 750000571 (Empower 3) – 1 day

Course DescriptionT his course shows how to use advanced acquisition and processing features of Empower Software. T he class uses bothtraditional and ApexTrack integration algorithms. This instructor led hands-on computer course is for experienced EmpowerSoftware users.

Course Topics ❱ Creating a sample set method template ❱ Developing a processing method manually in review ❱ Traditional versus ApexTrack integration ❱ Using integration events ❱ Named and timed groups ❱ Baseline subtractions ❱ Calibration and quantitation ❱ Altering samples and batch/background processing ❱ Reviewing results and calibration curves

Who Should AttendIndividuals who know Empower Software fundamentals and seek fast-paced, intensive training on the acquisition, processingand reviewing data features using the Pro Interface.

PrerequisitesAttendees must have at least 3 months experience using Empower Software.

Course NotesEach attendee will receive a course manual to keep for future reference and a Certificate of Attendance.



Empower Software Advanced Topics: Custom Fields and Reports

Language: Danish, Dutch, English, French, German, Italian, Spanish Location: Belgium, Denmark, Finland, Germany, Ireland, Italy, The Netherlands, Norway, Spain, Sweden, Switzerland

Ref.: 750000573 (Empower 3) – 1 day

Course DescriptionThis course shows you how to use the custom fields and report publisher features of Empower Software. Emphasis is placedon adding custom sample descriptions, creating custom calculations and reporting chromatography data and instrumentparameters.

Course Topics ❱ Creating custom fields ❱ Adding sample identifiers using the keyboard ❱ Using enumerated data type ❱ Calculations with peaks ❱ Boolean calculations with peaks ❱ Using text strings as the output for peak calculations ❱ Inter-sample calculations ❱ Creating custom reports—individual and summary report methods ❱ Customizing headers and footers with logos and special information ❱ Using Empower to generate reports for methods ❱ Creating composite groups ❱ Summarizing statistical information for replicate injections ❱ Summarizing component information for all results in a result set

Who Should AttendIndividuals who know Empower Software fundamentals and seek fast-paced, intensive training on the custom fieldsand report publisher features using the Pro interface.

PrerequisitesAttendees must have at least 3 months experience using Empower Software.


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Empower Software Advanced Topics: using Administrative Features for Productivity

Language: Danish, Dutch, French, English, ItalianLocation: Belgium, Denmark, Finland, Ireland, Italy, The Netherlands, Norway, Sweden, Switzerland

Ref.: 750000570 (Empower 3) – 1 day

Course DescriptionT his course shows some advanced features of Empower Software. Emphasis is placed on features that can increaseproductivity for the advanced user such as creating projects, creating and modifying chromatographic systems, userprivileges, creating view filters. This instructor led hands-on computer course is for experienced Empower Software users.

Course Topics ❱ Login window properties ❱ System policies and privileges ❱ Default strings ❱ User accounts, user types, user groups, group administrator ❱ Acquisition servers and chromatographic systems ❱ Cloning projects and multi-project searching ❱ Organizing and accessing information in Empower ❱ Creating view filters ❱ Using just-in-time view filters ❱ Comparing method versions ❱ Lock/unlock channels

Who Should AttendIndividuals who know Empower Software fundamentals and seek fast-paced, intensive training on advanced features using the Pro Interface. T he topics are for experienced users who want to access the flexibility built into Empower and customize their use of the software to meet individual lab application needs. This course uses Empower Software and the Pro Interface.

PrerequisitesAttendees must have at least 3 months experience using the Empower Software Pro Interface.




Empower 2/3 Software Advanced Topics with Lab

Language: DutchLocation: The Netherlands

Ref.: 750000572 – 4 days

Course DescriptionUse of the Pro Interface for organizing information, acquiring and processing data, and creating custom fields and reports.

Who Should AttendThis course is for users who know Empower Software or Millennium32 chromatography software fundamentals and seek fast-paced, intensive training on advanced features using the Pro Interface. The topics are for experienced users who want to access the flexibility built into Empower and customize their use of the software to meet individual lab application needs. If you are an experienced Millennium32 or Empower user, this instructor-led training course combined with hands-on computer use is the right course for you.

PrerequisitesAttendees must have at least four months experience using Millennium32 or Empower Software. Attending an Empower Fundamentals course is strongly recommended. Familiarity with the Pro Interface is helpful.

Course NotesEach attendee receives course manuals for reference and will receive a Certificate of Training. This course uses Empower Software and the Pro Interface.

Topics Covered ❱ Understanding system policies ❱ Default strings ❱ User accounts, user types, user groups,

group administrator ❱ Acquisition servers and chromatographic systems ❱ Cloning projects and multi-project searching ❱ Organizing and accessing information in Empower ❱ Creating view filters ❱ Using just-in-time view filters ❱ Comparing method versions ❱ Lock/unlock channels ❱ Creating a sample set method template ❱ Developing a processing method ❱ Traditional versus ApexTrack detection and

integration theory ❱ Global peak detection parameters ❱ Using integration events ❱ Noise and drift calculations in Empower ❱ System suitability overview ❱ Altering sample information and batch/

background processing ❱ Reviewing results and calibration curves ❱ Saving calibration curves, using an earlier

calibration curve, recalculating results ❱ Troubleshooting calibration curves ❱ Creating custom fields

❱ Adding sample identifiers using the keyboard or selection from a list you create for data entry ❱ Adding component specific numerical information ❱ Calculations with peaks ❱ Boolean calculations with peaks ❱ Using text strings as the output for peak calculations ❱ Inter-sample calculations(optional) ❱ Creating custom reports- individual and summary

report methods ❱ Customizing headers and footers with logos and

special information ❱ Using Empower to generate reports for methods ❱ Using data filters ❱ Creating composite groups ❱ Summarizing statistical information for replicate

injects of one standard ❱ Using overlay chromatograms and ordering tables ❱ Summarizing statistical information for replicate

injections of multiple standards ❱ Using composite groups to associate and order

chromatograms and tables ❱ Summarizing component information for all results

in a result set ❱ Arranging chromatograms and tables next to each

other on the report page ❱ Lab exercise

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Empower Software Enterprise System Administration and Maintenance

Language: English Location: Waters European Training Center in Saint-Quentin-en-Yvelines (France)

Ref.: 750000846 (Empower 3) – 3 days

Course DescriptionThis 3-day training session is focused towards the enhanced usage of features provided by the Empower Enterprise server operating system and a complete overview of all Empower Enterprise administration tasks, both on the server and throughout the network.

Topics Covered ❱ Windows OS considerations for a typical Empower Network ❱ Empower Architecture ❱ Enterprise Server installation overview ❱ Configuring TCP/IP, installing Empower Enterprise, configuring the database ❱ Installing an Empower Client ❱ Installing an Empower LAC/E™32

❱ Empower Acquisition Node configuration/license ❱ Administration tools ❱ Empower Enterprise global system police settings ❱ User management ❱ Creating users and groups, customizing user types and privileges ❱ Empower project management ❱ Creating projects, giving access to projects (hands-on) ❱ Nodes and chromatographic systems ❱ Communication pathways and buffering ❱ Oracle database 10g backup and recovery theory, recovery methods ❱ Recovery strategy overview, recommendations

Who Should AttendThese sessions are focused towards people responsible for maintaining the Empower Enterprise within their organization and who are familiar with the operating system of the clients and the server, but would like to further explore beneficial configuration possibilities. To get the maximum benefit from these sessions, certain training skills, other than the usual Empower Enterprise training that takes place as part of the installation, are needed. For instance, some knowledge of the Windows XP or Windows 7 operating system is essential.

PrerequisitesAttendees should have a minimum of 6 weeks experience operating the instrument.




Empower Software Enterprise Database Administration and Maintenance

Language: EnglishLocation: Waters European Training Center in Saint-Quentin-en-Yvelines (France)

Ref.: 750000575 (Empower 3) – 1 day (optional)

Course DescriptionT he 4th day is optional for Database Administrator experts. It covers Oracle database 10g administration and routine maintenance, and addresses the needs of those who are responsible for maintaining the Empower Database.

Topics Covered ❱ Oracle database 10g management•Empower Enterprise database maintenance•Checking free tablespace, increasing tablespace•Problem reporting, maintenance logs

❱ Troubleshooting•Problem reporting, maintenance logs (hands-on)•Common Oracle errors

❱ Database recovery•Recovery practice (hands-on)•Empower Enterprise database maintenance•Windows tools and Oracle tools (hands-on)

❱ Closing discussion and remarks

Who Should AttendIf you are preparing to update to the Empower Enterprise, consider the amount of data to migrate and the validation constraints, then select the most appropriate scenario. If you are not familiar with the Oracle 10g recovery procedures, this session will provide different cases in the form of exercises to train you on disaster recovery. To obtain the best performance from your Oracle 10g database it should be carefully maintained and tuned.

PrerequisitesTo get the maximum benefit from these sessions, certain training skills, other than the usual Empower Enterprise training that takes place as part of the installation, are needed. For instance, some knowledge of the Windows XP or Windows 7 operating system is essential.


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Empower Software Fundamentals using the Pro Interface

Language: Danish, English, Finnish, SwedishLocation: Denmark, Finland, Ireland, Norway, Sweden

Ref.: 750000635 – 1 day

Course DescriptionThis 1-day course shows how to efficiently collect, integrate, calibrate, quantitate and report chromatography data using Empower Chromatography Software via the Pro Interface. T he attendee uses the software throughout the entire course. T he instructor-led segments and the practice exercises reinforce the skills needed for success.

Topics Covered ❱ Utilization of the Pro Interface for acquisition, processing and using existing reports. ❱ Create instrument methods, method sets and sample set methods to run samples ❱ Develop processing methods ❱ Alter sample information ❱ Batch/background processing ❱ Find information ❱ Review results and calibration curves ❱ Modify existing report methods ❱ Summary exercise (optional)

Who Should AttendThis course is for new users of Empower Software who want to rapidly learn to use the Pro Interface.

PrerequisitesNone.

Course NotesEach attendee receives a course manual for reference during and following the course and will receive a Certificate of Attendance. This course uses only Empower Software and the Pro Interface.



Empower Software: Method Validation Manager (MVM)

Language: Danish, Dutch, English, French, GermanLocation: Belgium, Denmark, Finland, France, Germany, The Netherlands, Norway, Sweden

Ref.: 750000578 (Empower 3) – 3 days

Course DescriptionThis 3-day course is designed to walk you through all aspects of the Method Validation Manager option in Empower. It is designed to logically follow the steps in the Method Validation Workflow Process from creating a validation method protocol to reporting and signing off validation results. T his instructor-led hands-on computer course guides the attendee through the topics.

Topics Covered ❱ Overview of Method Validation ❱ Administering Method Validation activities ❱ Manager and Validation review ❱ Validation protocol methods ❱ Configuring validation tests (i.e., linearity, repeatability, accuracy, etc) ❱ Workflow of a validation study ❱ Creating and viewing validation results ❱ Reporting data and signing off Method Validation results ❱ Method Validation troubleshooting

Who Should AttendEmpower Software users or managers who want to use, set-up or administer the Method Validation Manager to automate the entire chromatographic method validation process.

PrerequisitesMVM only works with the Empower Pro Interface. Therefore, attendees must be familiar with Empower Pro Interface and know how to acquire process and print chromatographic data. A basic understanding of method validation theory is assumed.


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Empower Software: Self Use of SQT

Language: GermanLocation: Germany

Ref.: 750000302 – 1 day

Course DescriptionThe course explains the basics of qualification of HPLC/UPLC system using the Empower Software SystemQT option. It is aimed at users and laboratory managers who are responsible for the qualification of HPLC and UPLC systems. We explain how the different tests Empower SystemsQT™ qualification work and what to consider in implementation.

You get an interesting insight into the procedure for the qualification of our HPLC/UPLC systems and a good overview of the structure of the SystemsQT qualification folder. From the implementation of the manual OQ tests, the proper preparation of the system to the final evaluation of the performed tests SystemsQT all points of qualification are discussed.

In addition, we show you what to consider for the maintenance and repair of eligible systems, when a re-qualification is required and what are the consequences of not passing the test SystemsQT.

Topics Covered ❱ Structure of the SystemsQT folder ❱ Qualification overview ❱ Installation qualification ❱ Maintenance procedures ❱ Operational qualification ❱ Performance qualification ❱ Final approval ❱ Overview of the various qualification tests ❱ Procedures manual OQ ❱ Automatic Empower SystemsQT tests ❱ Declaration and pass/fail specifications of the tests

Who Should AttendThe course is aimed at all users and laboratory managers who are responsible for the Qualification of HPLC/UPLC systems.

PrerequisitesThe participants should be familiar with the basics of HPLC.




Empower Software: using the GPC Option with the Pro Interface

Language: DutchLocation: Belgium, The Netherlands

Ref.: 750000208 – 1 day

Course DescriptionThe course explains the use of Empower Chromatography Software to obtain “molecular weight/number etc. averages and distributions” of polymers. Attention is also paid to optimizing the data acquisition parameters and the parameters for processing the results (integration, calibration and quantification). Narrow and wide calibration capabilities are explained and the processing of GPC reports is discussed. The course is taught with hands-on on the PC and in the Pro Interface with references to the QuickStart Interface.

Topics Covered ❱ Data acquisition ❱ Calculations in process method ❱ Batch processing ❱ Processing results ❱ Alter sample ❱ Narrow/Broad standard calibration ❱ Universal calibration ❱ GPC reports

Who Should AttendThe course is for users who practice GPC analyzes and calculations in Empower.

PrerequisitesT he participants have the Start-Up explanation of Empower with several weeks experience and have followed either the QuickStart Interface (750000366/750000580) or the Pro Interface (750000391/750000568) course.


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Empower Software using the Pro Interface

Language: Dutch, English, French, GermanLocation: Belgium, Germany, Ireland, The Netherlands, Switzerland

Ref.: 750000568 (Empower 3) – 2 days

Course DescriptionThe learning objective of this 2-day course is to teach the user how to efficiently acquire, process and report chromatographic data using Empower. T his instructor-led hands-on computer and this course guides the attendee from log in to running samples through reporting. The course format includes exercises to reinforce the topics covered.

Topics CoveredUtilization of the Pro Interface for acquisition, processing, using and modifying reports.

❱ Empower overview and Log in ❱ Creating projects ❱ Creating sample set methods, instrument methods and method sets to run samples ❱ Developing a processing method to integrate, calibrate and quantitate ❱ Modifying sample information after data acquisition ❱ Batch/background processing of multiple chromatographic data files ❱ Viewing and sorting information in the project window ❱ Reviewing results and troubleshooting calibration curves ❱ Generating individual report methods ❱ Adding statistical calculations for peaks ❱ Overlaying chromatograms ❱ Associating tables with chromatograms: making composite report groups

Who Should AttendThis course is for anyone who wants to build a strong foundation to use Empower. If your answer is no to the following questions, this course is a good choice for you.•Do you know the difference between a sample set and a sample set method?•Can you develop a processing method then confidently batch process data to generate calibration curves and quantify unknowns? •Do you know how to generate printed reports which include document instrument settings and processing parameters?

PrerequisitesThe attendee must review the Empower Getting Started Guide before attending this class.

Course NotesEach attendee receives a course manual for reference during and following the course and will receive a Certificate of Attendance.



Empower Software: using the Software in a Regulated/Audited Environment

Language: English, French, German, ItalianLocation: France, Italy, Switzerland

Ref.: 750000581 (Empower 3) – 1 day

Course DescriptionThe course covers the features of the software dedicated to Empower FDA 21 CFR Part 11. The course is limited to 12students working on computers.

Topics Covered ❱ Definitions, electronic records, electronic signatures, closed system ❱ User management and system ❱ Audit trails ❱ Backup and restore

Who Should AttendThe course is designed for users having a common practice to Empower and wanting to deepen the functionality of thesoftware dedicated to the FDA regulation 21 CFR part 11.

Prerequisites None.


24


Empower Toolkit

Language: EnglishLocation: France, United Kingdom

Ref.: 750000630 – 4 days

Course DescriptionThis 4 day course covers the Empower Toolkit option and how it can be used to build custom applications. Hands-on programming exercises enhance and reinforce lecture material.Upon completion of the course attendees will have gained the ability to programmatically interface with Empower.

Who Should AttendThis course is intended for those wanting to build Empower Toolkit applications.

PrerequisitesAttendees must have some programming experience and want to apply this skill to building applications with the Empower Toolkit.

If you are capable of simple programming and are familiar with the object oriented concepts, this instructor-led training course combined with hands-on programming is the right course for you.

Attendees must have some experience with programming in an object oriented language, ideally .NET. A working knowledge of Empower Software is necessary. This course will teach how to use the Empower Toolkit, not how to program.

Course NotesEach participant will receive a course manual to keep for future reference and a Certificate of Attendance.

Topics CoveredNET Refresher

❱ Toolkit overview and background•The mechanics of the toolkit•Toolkit resources•Toolkit login•Working with Empower fields•Viewing Empower information•Data records•Using the toolkit in an enterprise environment•Top level toolkit objects overview•Methods in the Empower Toolkit•Generic method object•Method inheritance•Method set

❱ LC Proc method ❱ Export method ❱ Instrument method ❱ General toolkit objects ❱ Sample set method ❱ Alter sample ❱ Chrom ❱ Archive object ❱ DBProject object ❱ Working with instruments ❱ Processing request ❱ User and group admin ❱ Audit trail (search)



Using the Photodiode Array (PDA) Detector with Empower Software

Language: Danish, Dutch, English, French, German, Italian, Spanish, SwedishLocation: Austria, Belgium, Denmark, Finland, Germany, Ireland, Italy, The Netherlands, Norway, Spain, Sweden, Switzerland, United Kingdom

Ref.: 750000577 (Empower 3) – 1 day

Course DescriptionPractical use of the Waters 2996 PDA Detector and Empower Software provides the fundamental information that you need to acquire and utilize PDA data with confidence using Empower Chromatography Software. You will use Empower Software with PDA data sets throughout the entire course. T he instructor-led segments and the practice exercises reinforce the skills needed for utilizing PDA detection for problem-solving.

Topics Covered ❱ PDA overview ❱ Guidelines for collecting 3-dimensional data with the PDA detector ❱ Reviewing PDA data ❱ Building a processing method ❱ Peak purity ❱ Creating a UV library and library matching ❱ Reporting PDA data

Who Should AttendEmpower Software users who want to rapidly learn to utilize the capabilities of the PDA detector for 3D analysis.

PrerequisitesThe class attendee must be familiar with either the Empower QuickStart or Pro Interface. Knowing how to create a processing method with 2-dimensional chromatography data is helpful.


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Empower Data School Initiation 2D

Language: FrenchLocation: France

Ref. : 750000203 – 2 days

Course DescriptionThe attendee can acquire a common practice in the Empower Software with the 2 dimensional detection: run analysis, data processing (integration, calibration and quantification), and results printing.

Topics Covered ❱ General•Fundamentals•Software login

❱ Configuration•Definition and management of project •Archiving projects•Creation of a chromatographic system•“Instrument method”, and “Method set creation”•Real-time visualization of the chromatogram

❱ Research project•Access to project data•Filters and controls of results•Integration settings, calibration and quantification•Visualization of results•Printing•Access to the “Preview report”•Individual report•Summary report

Who Should AttendThe course is intended for users who have low knowledge in Empower and who are equipped with UV visible single or double wavelength(s), fluorometer, refractometer, electrochemical, conductivity, light scattering detector.

PrerequisitesSpecify your options when registering.

Course notesEach participant will receive a course manual to keep for future reference and a Certificate of Attendance.



Empower Data School Initiation 3D


Ref.: 750000465 – 3 days

Course DescriptionThe attendee can acquire a common practice in the software Empower with 3 dimensional detection (PDA, diode array detector): run analysis, data processing (integration, calibration and quantification), and results printing.

Topics CoveredTime shared with previous course “School data initiation 2D”

❱ Option PDA/diode array detector•Creating an “Instrument method•Features a “Method set” - Criteria of purity - Library - Spectral identification - Quantification - Specific r\eports

Who Should AttendThe course is intended for users who have low knowledge in Empower and who are equipped with a PDA, diode array detector.



28


Empower Data School Advanced 2D


Ref.: 750000464 – 2 days

Course DescriptionT he attendee can master the Empower Software detection in two dimensions by addressing the following topics: configuration, creating custom fields and filters, run analysis, data processing (integration, calibration and quantification), and data reporting.

Topics Covered ❱ General•Fundamentals•Software access - privileges users•Creation of a chromatographic system•Creating a project•Filters•Information management•Custom fields

❱ Injections•“Run samples page”•“Instrument method”, and “Method set”•Run a single analysis•Run a sample set•Real-time visualization of the chromatogram

❱ Results•Integration settings, calibration and quantification•Visualization of results

❱ Reports•Creation of an individual report•Creating a summary report•Operating procedure

❱ Refresher training•Suitability option•Validation of results

Who Should AttendThe course is intended for users who routinely practice Empower detection in two dimensions (UV visible single or double wavelength(s), fluorometer, refractometer, electrochemical, conductivity, light scattering detector).





Empower Data School Advanced 3D


Ref.: 750000204 – 3 days

Course Description The attendee can master the Empower Software detection in three dimensions (PDA, diode array detector) by addressing the following issues: configuration, creating custom fields and filters, run analysis, data processing (integration, calibration, quantification, spectral identification and purity spectral calculations), and reporting.

Topics CoveredTime shared with previous course, “Data school advanced 2D” option PDA/diode array detector.

❱ Creating an “Instrument method” ❱ Features of a “Method set”•Criteria of purity•Library•Spectral identification•Quantification•Specific reports

Who Should AttendThe course is intended for users who routinely practice Empower detection in three dimensions (PDA, diode array detector).



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[ LABORATORY INFORMATICS ] MASSLYNX

31

BiopharmaLynx

Language: Dutch, French, EnglishLocation: Belgium, Denmark, Finland, Ireland, Norway, Sweden, The Netherlands, United Kingdom

Ref.: 750000474 – 1 day

Course Description A 1-day training course designed for BiopharmaLynx™ users to cover optimised data acquisition, processing and interpretation. During this training course there will be opportunity to work with other attendees and Waters application experts on this MassLynx® application manager.

Topics Covered ❱ A review of experiment design ❱ Peptide mapping and intact analysis ❱ BiopharmaLynx processing and method creation ❱ Result evaluation and interpretation ❱ Validation of software assignments using MSE

Daily EventsThe major focus will be hands on data processing with defined exercises to reinforce the skills taught.

Who Should AttendMS and MassLynx users who would like to utilize functionality offered by BiopharmaLynx application manager.

PrerequisitesAttendance of a basic operator training course for Tof Mass Spectrometer. Usage of the current software revision of MassLynx with BiopharmaLynx application manager.


32


ChromaLynx and ChromaLynx XS

Language: Dutch, English, French, SwedishLocation: Belgium, Denmark, Finland, France, Ireland, The Netherlands, Norway, Sweden, United Kingdom

Ref.: 750000536 – 2 days

Course Description A 2-day training course designed for ChromaLynx™ users to cover optimized data acquisition, processing and interpretation. During this training course there will be opportunity to work with other attendees and Waters application experts on this MassLynx application manager. T he ChromaLynx Software package reliably and automatically detects chromatographic peaks. It is essential to perform deconvolution in complex mixture analysis in order to fully profile the extract. It is able to accurately produce pure spectra from unresolved closely eluting peaks. Exact mass measurement aids in the confirmation of identity of components in a complex matrix. ChromaLynx Software works with both high and low resolution LC-MS, GC-MS, LC-MS/MS (Q-Tof™) and GC-MS/MS (Q-Tof) data.

Topics CoveredThis training course is designed to teach the operator:

❱ The ChromaLynx XS work-flow ❱ ChromaLynx Identify – profiling of complete sample. ❱ ChromaLynx Targeted – targeted screening and confirmation. ❱ ChromaLynx Compare – comparison of complex samples for chromatographic differences and similarities. ❱ POSI±IVE – Automated identification and quantification of targeted analytes with spectral confirmation. ❱ Generating reports.

Default data sets and exercises will be provided on this largely practical training course. Customers are encouraged to bring data sets and problems to the workshop.

Who Should AttendMS and MassLynx users who would like to utilise functionality offered by ChromaLynx XS application manager.

PrerequisitesAttendance of a basic operator training course for Mass Spectrometer. Usage of the current software revision of MassLynx with ChromaLynx application manager.




MarkerLynx XS

Language: Dutch, English, FrenchLocation: Belgium, Denmark, Finland, France, Ireland, Norway, Sweden, The Netherlands, United Kingdom

Ref.: 750000473 – 2 days

Course Description A 2-day training course designed for MarkerLynx™ users to cover optimized data acquisition, data processing, and interpretation. T hat also offers the opportunity to work with other attendees and Waters application experts on the MassLynx application manager.

Topics Covered ❱ A review of experiment design ❱ Peak detection and data filtering ❱ Advanced data analysis using eXtended Statistics ❱ Database searching ❱ Daily events ❱ Defined data exercises to reinforce the skills taught

Who Should AttendMS and MassLynx users who would like to utilize functionality offered by MarkerLynx XS application manager.

PrerequisitesAttendance of appropriate MS system operator training course. Usage of the current software revision of MassLynx with MarkerLynx application manager.


34


MassLynx Data School

Language: Danish, Dutch, English, French, German, Spanish, SwedishLocation: Austria, Denmark, Finland, France, Ireland, Norway, Spain, Sweden, The Netherlands, United Kingdom

Ref.: 7560000356 – 1 day

Course Description This course covers the basic operation of the MassLynx Software package as used on LC-MS and LC-MS/MS system. Hands-on MassLynx Software training enhances and reinforces lecture material. Upon completion of this course, the attendee should be able to confidently use the MassLynx Software.

Topics Covered ❱ Introduction to MassLynx version 4.1 ❱ MassLynx architecture ❱ Tuning and calibrating ❱ Data acquisition ❱ Data processing, reporting data ❱ Quantitation and reporting ❱ MassLynx other tools ❱ Introduction to OpenLynx™

Who Should AttendThis course is for users who have no experience or limited skills with MassLynx version 4.1 software. This course is also for infrequent users of MassLynx version 3.5 who will now use MassLynx version 4.1. Due to their presence in MassLynx version 4.1, an introduction to QuanLynx™ and OpenLynx application managers will also be covered.

PrerequisitesNone.




MassLynx Data School 2D

Language: French, GermanLocation: France, Germany

Ref.: 750000428 – 2 days

Course Description This course covers the basic operation of the MassLynx Software package as used on LC-MS and LC-MS/MS system. Hands-on MassLynx Software training enhances and reinforces lecture material. Upon completion of this course, the attendee should be able to confidently use the MassLynx Software.

Topics Covered ❱ Introduction to MassLynx version 4.1 ❱ MassLynx Architecture ❱ Tuning and calibrating ❱ Data acquisition ❱ Data processing, reporting data and library searching ❱ Quantitation and reporting ❱ MassLynx other tools ❱ Introduction to OpenLynx


Who Should AttendThis course is for users who have no experience or limited skills with MassLynx version 4.1 software. This course is also for infrequent users of MassLynx version 3.5 who will now use MassLynx version 4.1. Due to their presence in MassLynx version 4.1, an introduction to QuanLynx and OpenLynx application managers will also be covered.

PrerequisitesNone.


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MetaboLynx XS

Language: Dutch, English, French, SwedishLocation: Belgium, Denmark, Finland, France, Ireland, Norway, the Netherlands, Sweden, United Kingdom

Ref.: 750000358 – 2 days

Course Description A 2-day training course designed for MetaboLynx™ users to cover optimised data acquisition, processing and interpretation. During this training course there will be opportunity to discover or improve knowledge in MetaboLynx features and work with other attendees and Waters application experts on this MassLynx application manager.


❱ Data acquisition ❱ The dealkylation tool ❱ Mass defect filtering ❱ MetaboLynx XS browser ❱ MSE data processing ❱ MassFragment™ ❱ Automating MS/MS run lists


Who Should AttendMS and MassLynx users who would like to utilise functionality offered by MetaboLynx XS application manager.

PrerequisitesAttendance of appropriate MS system operator training course. Usage of the current software revision of MassLynx with MetaboLynx application manager.




Open Access Login Application Manager

Language: Danish, Dutch, English, French, SwedishLocation: Belgium, Denmark, Finland, France, Ireland, The Netherlands, Norway, Sweden, United Kingdom

Ref.: 750000359 – 2 days

Course Description This course covers the operation of the Open Access Login Software package as used on LC-MS and LC-MS/MS system. Hands-on Open Access Login Software training enhances and reinforces lecture material. Upon completion of this course, the attendee should be able to confidently use the Open Access Login Software.


❱ Open Access Login Software installation ❱ Open Access Software overview ❱ Wizard configuration ❱ Instrument management ❱ Samples management ❱ Computer management ❱ Computer maintenance ❱ Network protocol ❱ Troubleshooting ❱ OA toolkit software overview ❱ Remote status monitoring

Who Should AttendThis course is dedicated to LC-MS or LC-MS/MS System administrators; people who are responsible for the equipment and who have limited skills or low experience with Open Access Login Software. A network part is added to improve computer configuration, software installation and understanding. If you are an inexperienced MassLynx user, this instructor-led training course combined with hands-on computer use is the right course for you.

PrerequisitesAttendees must have at least few weeks experience using Open Access Login application manager Software. A good working knowledge of the MassLynx Software is required.


38


OpenLynx Software

Language: Danish, Dutch, English, French, SwedishLocation: Belgium, Denmark, Finland, France, Ireland, The Netherlands, Norway, Sweden, United Kingdom

Ref.: 750000153 – 1 day

Course Description This course covers the operation of the OpenLynx Software package as used on LC-MS and LC-MS/MS sytem. Hands-on OpenLynx Software training enhances and reinforces lecture material. Upon completion of this course, the attendee should be able to confidently use the OpenLynx Software.

Topics Covered ❱ MS reminder ❱ MassLynx reminder ❱ OpenLynx Software overview ❱ OpenLynx set-up ❱ OpenLynx method building ❱ Data processing ❱ OpenLynx browser ❱ Report method building ❱ Data review ❱ OpenLynx manager ❱ Data sending configuration ❱ Data printing


Who Should AttendThis course id dedicated to LC-MS or LC-MS/MS system administrators; people who are responsible for the equipment and who have limited skill level or low experience with OpenLynx Software. If you are an experienced MassLynx user, this instructor-led training course combined with hands-on computer use is the right course for you.

PrerequisitesAttendees must have at least few weeks experience using OpenLynx application manager software. A good working knowledge of the MassLynx Software is also required.




QuanLynx and TargetLynx Application Manager

Language: Danish, Dutch, English, French, German, SwedishLocation: Belgium, Denmark, Finland, France, Germany, Ireland, The Netherlands, Norway, Sweden, United Kingdom

Ref.: 750000357 – 1 day

Course Description T his course covers the basic operation of the QuanLynx and TargetLynx™ Software package as used on LC-MS and LC-MS/MS system.


❱ Quantification process overview ❱ Using external, internal standard ❱ QuanLynx software overview ❱ Sotware architecture, processing method building ❱ Data processing, data review ❱ QuanOptimize™ ❱ Software overview and method building ❱ Introduction to TargetLynx ❱ TargetLynx software overview ❱ Software architecture, processing method building ❱ Data processing


Who Should AttendThis course is for users who have no experience or limited skills with QuanLynx and TargetLynx Software. If you are an experienced MassLynx user, this instructor led training course combined with hands-on computer use is the right course for you.

PrerequisitesAttendees must have 6-8 weeks experience using QuanLynx and TargetLynx application manager software. A good working knowledge of the MassLynx Software is required.


40


[ LABORATORY INFORMATICS ] NUGENESIS

41

NuGenesis SDMS System Administration

Language: EnglishLocation: Waters European Training Center in Frechen (Germany)

Ref.: 750000377 – 3 days

Course Description The 3-day training course is designed for NuGenesis® SDMS System Adminstrators who need to learn how to use and set up the components of the SDMS application.

Topics CoveredAdministration of systems that use SDMS software in a network environment by understanding network and system fundamentals.

❱ SDMS architecture overview ❱ VISION overview for administrators ❱ SDMS administrator ❱ SDMS server ❱ Audit reasons ❱ Manage storage ❱ View builder ❱ Groups ❱ Users ❱ Privileges ❱ Search groups ❱ Print capture utility ❱ Creating file capture project, archive templates and capture/restore file data ❱ Creating projects ❱ Creating UNIFI template for print data project ❱ Data adaptors ❱ Service configuration console ❱ Offline storage manager ❱ SDMS system maintenance

Who Should AttendThis course is for those who perform system administration in a SDMS environment.

PrerequisitesElementary familiarity with the network environment in your organization is necessary. This includes knowing if your SDMS installation is part of a corporate network or an isolated network and knowing the number of clients. SDMS terminology is NOT covered in this course, so a familiarity with the system vocabulary is a must. T his prerequisite can be satisfied by taking the end-user course.


42


NuGenesis SDMS and SDMS Vision Publisher™ Software Development Kit


Ref.: 750000315 – 2 days

Course Description The course on the NuGenesis SDMS Software Development Kit (SDK) is designed for base level programmers to learn how to integrate and develop customer applications utilizing the NuGenesis SDMS and SDMS Vision Publisher (VP) SDK components. This course is a high level overview to give the participant a basic understanding of how to program using the toolkit. The class will be demonstrating the toolkit ability with Visual basic as the programming language, but individualized help will be available for C++ and Java throughout the course.

Topics CoveredSDK is designed for base level programmers to learn how to integrate and develop customer applications utilizing the NuGenesis SDMS SDK component:

Introduction to the Waters NuGenesis SDMS and Vision Publisher SDK ❱ SDMS and Vision Publisher product overview ❱ The SDK APIs ❱ Using the SDK ❱ Sample SDK programs ❱ Scripting

Who Should AttendThis course is for those developers who will be developing APIs and scripting utilizing SDMS and the VP SDK toolkit.

PrerequisitesParticipants must attend the SDMS and VP Administrator training classes prior to attending the SDMS toolkit class.




NuGenesis 8 Lab Execution Method Editor


750000741 – 3 days

Course DescriptionThis course will enable a NuGenesis ELN /Vision Publisher Administrator to create a Form Designer or LE ME forms specific to their work environment. The course will provide hands-on experiences, best practices and workflow suggestions.

Topics Covered ❱ Overview of LE ME function ❱ Creating forms ❱ Basic form functions ❱ LE ME database functions ❱ Review of serial device support ❱ Writing to ELN inventory

Who Should AttendELN administrators or power users who will be creating forms for ELN.

PrerequisitesNuGenesis 8 ELN /Vision Publisher Administrator.


44


NuGenesis 8 ELN Administrator


Ref.: 750000739 – 3 days

Course DescriptionThis course enables a system administrator to create an environment for end-users using basic NuGenesis ELN/Vision Publisher functions. This course will provide best practices as well as workflow suggestions.

Topics Covered ❱ Document creation ❱ Document configuration ❱ Section and document properties ❱ Create document template ❱ Searching for documents ❱ User administration ❱ System and user preferences ❱ Data from external systems

Who Should Attend Users who will set up and/or configure the NuGenesis 8 ELN application.

PrerequisitesNone.

Course NotesContact the NuGenesis 8 training team for information about Vision Publisher 7.1 courses. Each attendee will receive a course manual to keep for future reference and a Certificate of Attendance.



NuGenesis 8 Advance System Administration and Infrastructure


Ref.: 750000740 – 3 days

Course DescriptionFor NuGenesis SDMS users, this is a hands-on course provides information and practice on architecture overview, application component data flow, identify the points of failure for file and print by components, troubleshooting, web server configuration and customization, important configuration and log files, and installation requirements. For NuGenesis ELN /Vision Publisher users, this course provides information on the new welcome screen and how to use ‘My Work’, ‘Overview of Inventories’ and ‘Sample Management’.

Topics Covered ❱ Review NuGenesis 8 architecture ❱ Review application components ❱ Review application configuration and log files ❱ Identify points of failure and troubleshooting

Who Should AttendNuGenesis Administrators.

PrerequisitesAdministration course or appropriate administration modules.

Course NotesContact Waters for information on the selection of appropriate on-site training modules. Each attendee will receive a course manual to keep for future reference and a Certificate of Attendance.

46


NuGenesis 8 SDMS Administration


Ref.: 750000738 – 3 days

Course DescriptionThis course will allow a system administrator to create an environment for end-users using basic NuGenesis 8 SDMS functions. This course will also provide best practices as well as workflow suggestions.

Topics CoveredAdministration of systems that use NuGenesis 8 SDMS in a network environment by understanding network and system fundamentals:

❱ SDMS overview and architecture ❱ Vision web interface ❱ SDMS administration ❱ Project set up and configuration ❱ Creating users/groups/ privileges ❱ Creating print capture templates: unify and extraction ❱ Creating file capture template: archive ❱ Create search groups ❱ Create data retention projects and review legal holds

Who Should AttendUsers who perform system administration in a SDMS environment.

PrerequisitesNone.

Course NotesContact the NuGenesis 8 training team for information about SDMS 7.1 courses. Each attendee will receive a course manual to keep for future reference and a Certificate of Attendance.



SDMS Vision Publisher/eLab Notebook System Administration


Ref.: 750000346 – 3 days

Course Description This will allow a System Administrator to create an environment for end-users using Scientific Data Management System (SDMS) Vision Publisher (V P) basic V P/eLab Notebook™ functions. T his course will also provide best practices as well as workflow suggestions.

Topics CoveredAdministration of systems that use SDMS VP/eLab Notebook Software in a network environment by understanding network and system fundamentals.

❱ Software introduction ❱ User management ❱ Project administration ❱ Documents and section types ❱ Section type administration ❱ Document templates ❱ SDMS browser ❱ Signature process ❱ Workspaces ❱ System configuration ❱ IIS configuration ❱ Preferences ❱ Instrument results ❱ System data

Who Should AttendThis course is for those who perform system administration in an SDMS VP/eLab Notebook environment.

PrerequisitesElementary familiarity with the network environment in your organization is necessary. This includes knowing if your SDMS VP/eLab installation is part of a corporate network or an isolated network. If the Implementation Strategy Course was taken as a prerequisite, this course will incorporate all decisions made therein.


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49

[ NOTES ]

Waters Educational Services: Fast Facts

n 6,000 users trained each year

n 6 corporate training centers across the globe

n More than110 training locations in 30 countries

n Specialized and certified instructors

n More than 95 courses covering theory, practice, maintenance, and qualification:n LC, MS, UPLC small and large applicationsn Informaticsn Waters Instruments and Softwaren General Chromatography and LC-MS fundamentals n Compliancen SFC

n Flexible delivery options: class room, on-site, and online

n Most courses available at your location

Special Discounts for Warranty and Support Plan Customers

If your HPLC, UPLC, and mass spectrometry systems are under a support warranty or plan, you can receive up to 20% discount on any instrument, software, or application course. Please contact your local Waters training coordinators for more information.

50

[ ULTRAPERFORMANCE LC (UPLC) TECHNOLOGY ]

51

ACQUITY UPLC for Laboratory Practitioners

Language: Danish, Finnish, English, French, German, Spanish, SwedishLocation: Austria, Denmark, Finland, France, Germany, Norway, Spain, Sweden

Ref.: 750000327 – 2 days

Course Description This course explains how the ACQUITY UPLC® System combines new chemistry with advances in instrumentation to access increased speed, resolution and sensitivity in chromatographic analysis. Included in the course are exercises such as becoming familiar with the ACQUITY® Console software, priming the instrument, running test and sample solutions, and method transfer.

Topics Covered ❱ Understanding the unique differences between HPLC and UPLC with•An introduction and global overview•An in-depth look at UPLC theory and chemistry•An overview of the ACQUITY UPLC System’s hardware and configuration

❱ Using the ACQUITY Console software for:•Priming the Binary Solvent Manager and Sample Manager•Calibrating the Sample Manager•Setting default parameters•General troubleshooting techniques, including tips and tricks

❱ Method transfer:•Theory behind transfer of method from HPLC to UPLC•Using the ACQUITY UPLC Column Calculator

Who Should AttendThis course is for individuals who want to push the limits of conventional HPLC and understand the chemistry, operating principles of the ACQUITY UPLC. UPLC presents the possibility to extend and expand the utility of this widely used separation science.

PrerequisitesAttendees should be familiar with the basic principles of HPLC.


52

[ ULTRAPERFORMANCE LC ]

ACQUITY UPLC Maintenance

Language: Danish, Dutch, Finnish, English, French, German, Spanish, SwedishLocation: Austria, Belgium, Denmark, Finland, France, Germany, The Netherlands, Norway, Spain, Sweden

Ref.: 750000328 – 1 day

Course Description This course explains how to perform routine maintenance for optimal performance. Included in this course are exercises that will enable you become familiar with routine and more advanced user maintenance procedures.

Topics Covered ❱ Maintaining your ACQUITY UPLC System for optimal performance and reliability by:•Replacing components during a routine maintenance such as the pump head seals, plunger, check valves, injection needle and syringes•Having information to change the detector lamp and clean the flow cell•General troubleshooting techniques, including tips and tricks•Utilizing Connections INSIGHT® with its Intelligent Device Management (IDM) technology

Who Should AttendThis course is for individuals who are responsible for the day-to-day user maintenance of their ACQUITY UPLC System.

PrerequisitesAttendees should be familiar with the basic principles of HPLC, and preferably have followed the “ACQUITY UPLC for Laboratory Practitioners” course.




ACQUITY UPLC School with Empower


Ref.: 750000289 – 3 days

Course DescriptionThe ACQUITY UPLC System has important technological innovations at the stationary phase and instrumentation and simultaneously improves the analysis speed, sensitivity and resolution. The course explains the principles of the new UPLC and discusses theoretical and practical aspects related to hardware, to the column, the transposition of methods and Empower Software. The presentation is done in Empower 3.

Topics Covered ❱ Empower 3 Software configuration ❱ Methods of acquisition, calculation and reporting ❱ Launch processing and analysis: pages “Run Samples”, “Channels” and “Results” ❱ UPLC Technology ❱ Theory of UPLC ❱ Description of the ACQUITY UPLC ❱ UPLC method development and transfer of HPLC methods to UPLC ❱ Workshop ❱ The use of the ACQUITY UPLC Console ❱ Booting the system ❱ Defaults ❱ Injections of test samples ❱ Precautions for use ❱ Diagnosis and tests ❱ Workshop ❱ Ongoing maintenance of the ACQUITY UPLC ❱ Changing rooms: joints pump heads, pistons, needle, lamp

Who Should AttendThe course is designed for users of ACQUITY UPLC controlled by the software Empower 3; this is additional training for the startup of the unit. Trainees should know the principles of the HPLC technique.


54


ACQUITY UPLC School for the Lab Practitioner

Language: Dutch, English, FrenchLocation: Austria, Belgium, France, The Netherlands

Ref.: 750000451 – 1 day

Course Description The aim of this training course is to update the knowledge of the ACQUITY UPLC user with the latest developments in ACQUITY UPLC Technology and working practices. Also an opportunity to evaluate your own knowlege of this important technology will be offered.

Topics Covered ❱ Review of Latest Feature Developments •Hardware•Software•Chemistry

❱ Introduction to UPLC Method Development•Mobile Phase selection•Column selection

❱ HPLC to UPLC method transfer review •Considerations•Main rules to follow

❱ Tips and Tricks•Major contaminants and their sources•Controlling and troubleshooting contamination•Cleaning to eliminate contamination

Who Should AttendThis course is for individuals who are responsible for the operation of their laboratory’s ACQUITY UPLC System and would like to update themselves with the latest features and practices.

PrerequisitesA working knowledge of ACQUITY UPLC. Attendance of a Waters UPLC training course, e.g. ACQUITY UPLC for Lab Practitioners would be advantageous.




ACQUITY UPLC H-Class for Laboratory Practitioners and ACQUITY UPLC H-Class Bio

Language: Danish, English, French, German, Italian, Spanish, SwedishLocation: Austria, Denmark, Finland, France, Germany, Ireland, Italy, Norway, Spain, Sweden, Switzerland, The Netherlands, United Kingdom

Ref.: 750000523 – 2 days (H-Class)Ref.: 750000551 – 2 days (H-Class Bio)

Course Description Instruction for the ACQUITY UPLC H-Class is a two day course designed to offer a solid understanding of ACQUITY UPLC H-Class Chemistry, Instrumentation and Software. Instrument overview, chromatographic concepts as well as method transfer and development will be taught.

Topics Covered ❱ ACQUITY UPLC H-Class and H-Class Bio introduction and overview ❱ HPLC/UPLC Chemistry ❱ Using the console•Starting the system•Priming the pump and fluidic pathway•Diagnostics

❱ Quaternary Solvent Manager ❱ Isocratic and gradient solvents ❱ Sample Manager•Injections mechanism using Flow Through Needle (FTN) design

❱ System configuration ❱ Detection mechanisms ❱ Method transfer and development ❱ Connections INSIGHT ❱ Practical lab exercises•Determine system dwell volume•System setup running test solutions•Using the ACQUITY UPLC Calculator•Using the Column Selectivity Chart

Who Should AttendThe course is designed for attendees who currently use the ACQUITY UPLC H-Class System. For the user who is involved in instrument operation and for those whose responsibilities include method transfer and/or method development.

PrerequisitesAttendees should have the ACQUITY UPLC H-Class Systems installed in their lab. A working knowledge of Empower 2 or MassLynx is strongly recommended.


56


Maintaining the ACQUITY UPLC H-Class Practitioners and UPLC H-Class Bio

Language: Danish, Dutch, English, Finnish, French, German, Italian, Spanish, SwedishLocation: Belgium, Denmark, Finland, France, Germany, , Ireland, Italy, The Netherlands, Norway, Spain, Switzerland, Sweden, Switzerland, United Kingdom

Ref.: 750000524 – 1 day (H-Class)Ref.: 750000552 – 1 day (H-Class Bio)

Course Description This course covers basic troubleshooting and routine maintenance on the ACQUITY UPLC H-Class and H-Class Bio System. Participants will learn how to carry out Performance Maintenance (PM) on an ACQUITY UPLC H-Class System and perform the built in diagnostics to verify the repair/maintenance to ensure the instrument is at its highest performance level.

Topics CoveredMaintaining your ACQUITY UPLC H-Class System for optimal performance and reliability by:•replacing components during a routine maintenance such as the pump head seals, plunger, and needle assembly•having information to change the detector lamp and clean the flow cell•general troubleshooting techniques, including tips and tricks

Who Should AttendThe course is designed for users who currently use the ACQUITY UPLC H-Class Systems.

PrerequisitesAttendees should be familiar with the basic principles of HPLC, and preferably have followed the ‘‘ACQUITY UPLC for Laboratory Practitioners’’ course.




Who Should AttendThe course is designed for users who currently use the ACQUITY UPLC I-Class Systems.

PrerequisitesAttendees should be familiar with the basic principles of HPLC, and preferably have followed the ‘‘ACQUITY UPLC for Laboratory Practitioners’’ course.


Operation of ACQUITY UPLC Systems (Classic, H-Class & I-Class)

Language: Danish, English, French, German, Italian, Spanish, SwedishLocation: Austria, Denmark, Finland, France, Germany, Italy, Norway, Spain, Sweden, Switzerland, The Netherlands, United Kingdom

Ref.: 750000607 – 2 days

Course DescriptionThis course explains how the ACQUITY UPLC I-Class system combines new chemistry with advances in instrumentation to access increased speed, resolution and sensitivity in chromatographic analysis.

Topics Covered ❱ UPLC theory and chemistry•UPLC principle and theory •Resolution and peak capacity •UPLC column chemistries •Column design •System bandspreading

❱ ACQUITY hardware •Solvent manager •Degasser •Sample manager •Column manager •eCord Technology •Detectors

❱ ACQUITY Console Software •Overview of console software •Module functions and diagnostics •Interactive displays •Plots and logs •Preparing for analysis •Characterizing needle and loop volume •Instrument method parameters

❱ Method transfer, HPLC to UPLC •Method transfer considerations •Transfer of isocratic methods •Transfer of gradient methods •System delay volume •Using the ACQUITY Column Calculator

❱ Troubleshooting tips and tricks •Mobile phase preparation •Controlling bacterial growth •Column maintenance •Tips and tricks for the solvent and sample manager •Optimal detector settings •Troubleshooting peak shape problems and carry over

❱ Hands-on exercises •Column efficiency test •System precision test •Gradient performance test •Method transfer exercise

58


ACQUITY UPLC I-Class Maintenance

Language: Danish, Dutch, English, Finnish, French, German, Italian, Spanish, SwedishLocation: Austria, Belgium, Denmark, Finland, France, Germany, Italy, The Netherlands, Norway, Spain, Sweden, Switzerland, United Kingdom

Ref.: 750000608 – 1 day

Course DescriptionThe course covers how to do performance maintenance on the ACQUITY UPLC I-Class system, including changing seals, pistons and injector needle.

Topics Covered ❱ ACQUITY system overview ❱ ACQUITY console software ❱ Changing pump seals, pistons and check valves ❱ Changing injector needle and syringes ❱ Running the static leak test ❱ X, Y, Z axis calibration ❱ ACQUITY diagnostics

Who Should AttendIndividuals who needs to perform maintenance on the ACQUITY UPLC System.

PrerequisitesAttendees should be familiar with the basic principles of UPLC.




ACQUITY UPC2 for Lab Practitioners

Language: Danish, Dutch, English, French, German, Italian, Spanish, SwedishLocation: Belgium, Denmark, Finland, France, Germany, Italy, The Netherlands, Norway, Spain, Sweden, Switzerland, United Kingdom

Ref.: 750000623 – 2 days

Course DescriptionThis course explains how the ACQUITY UPC2® System combines new chemistry with advances in instrumentation to access increased speed, resolution and sensitivity in chromatographic analysis. Included in the course are exercises such as basic login for Empower and MassLynx, becoming familiar with the ACQUITY Console software, priming the instrument, running test and sample solutions, and method transfer.

Topics Covered ❱ Understanding the unique differences between SFC and UPC2® with an introduction and global overview ❱ A brief refresher of SFC and an in-depth look at UPC2 chemistry ❱ An overview of the ACQUITY UPC2 System’s hardware and configuration ❱ Using the ACQUITY Console software for: •Priming the Binary Solvent Manager and Sample Manager •Calibrating the Sample Manager •Setting default parameters

❱ Maintaining your ACQUITY UPC2 System for optimal performance and reliability: ❱ Method Transfer and optimisation from SFC to UPC2

❱ General troubleshooting techniques, including tips and tricks ❱ Utilizing Connections INSIGHT with its Intelligent Device Management (IDM) technology

Who Should AttendThis course is for individuals who want to push the limits of conventional SFC and understand the chemistry, operating principles and user maintenance of the ACQUITY UPC2 System. UltraPerformance SFC™ presents the possibility to extend and expand the utility of this widely used separation science.

PrerequisitesAttendees should be familiar with the basic principles of SFC.


60


Maintaining ACQUITY UPC2

Language: Danish, Dutch, English, Finnish, French, German, Italian, Spanish, SwedishLocation: Belgium, Denmark, Finland, France, Germany, Italy, The Netherlands, Norway, Spain, Sweden, Switzerland, United Kingdom

Ref.: 750000624 – 1 day

Course Description This course explains how to operate and perform routine maintenance for optimal performance. Included in this course are exercises that will enable you to become familiar with routine and more advanced user maintenance procedures.

Topics Covered ❱ Maintaining your ACQUITY UPC2 System for optimal performance and reliability by replacing components

during a routine maintenance such as the pump head seals, plunger, and needle assembly ❱ Having information to change the detector lamp and clean the flow cell ❱ General troubleshooting techniques, including tips and tricks ❱ Utilising Connections INSIGHT with its Intelligent Device Management (IDM) technology

Who Should AttendThis course is for individuals who are responsible for the day-to-day maintenance of their UltraPerformance Convergence Chromatography™ (UPC2) System.

PrerequisitesAttendees should be familiar with the basic principles of HPLC, and have followed the “ACQUITY UPC2 for Laboratory Practitioners” course.




ACQUITY QDa with Empower

Language: Danish, English, Finnish, German, Italian, Swedish Location: Denmark, Finland, Norway, Sweden, Switzerland, United Kingdom

Ref.: 750000833 – 2 days

Course Description T his course introduces you to the ACQUITY QDa® Detector hardware and operating principles in an Empower Software environment. Students are shown ACQUITY QDa Detector specific topics within the Empower Software, such as instrument method settings and working with mass spectral data in the review window. Lab exercises are performed to practice and reinforce Empower MS data processing concepts needed to become successful with the QDa® Detector and Empower Software.

Topics Covered ❱ ACQUITY QDa Detector principles and hardware ❱ Preparing to run•ACQUITY QDa Detector Console•ACQUITY QDa Detector instrument method settings

❱ Empower review 3D window overview•Toolbar functions•Table properties•Extracting chromatograms•Extracting spectra•Spectrum plot properties•3D view•Developing a processing method for 3D data

❱ Mass analysis window (for Empower 3 FR2)•Extracting a channel•MS spectra extraction•Mass analysis window toolbar•Mass analysis window view properties

❱ User maintenance•Source part replacement/cleaning•Capillary replacement

Who Should AttendEmpower software users who want to rapidly learn the capabilities of the ACQUITY QDa Detector.

PrerequisitesAttendee must be familiar with Empower Software using the Pro Interface. Knowing how to work with 2-dimensional chromatography data in Empower Software as well as an understanding of foundational LC-MS principles is helpful.


62


63

[ NOTES ]

Waters Software Deployment Services

Reduce the time and cost of your software deploymentW hether you are upgrading your software system or installing software for the first time, Waters consultants have the skills and expertise to make your implementation a success.

Available deployment services include:n Project Management

n Architecture and Infrastructure Consultation

n Installation/Configuration Assistance

n Application Assessment/Audit Services

n Software Validation

n Instrument/Software Qualification

n Training Services

n Integration Services

To learn more, go to

www.waters.com/deployment

64

[ OPERATION AND MAINTENANCE ]

65

Alliance 2695 Operation and Diagnostics

Language: English, German, SpanishLocation: Germany, Ireland, Spain, United Kingdom

Ref.: 750000427 – 1 day

Course Description T he aim of the course is to give the participants a thorough understanding of the operating principles in the 2695 separations module. After completion of the course the participants should be able to identify and diagnose instrumentation issues to keep their Alliance® HPLC System running at the highest level of performance.

Topics Covered ❱ System Overview/ Design of the 2695 ❱ Solvent and sample management technologies ❱ Direct functions and diagnostics ❱ Instrument setup and troubleshooting procedures ❱ Dry/Wet Prime ❱ Seal wash and Needle wash ❱ Injector compression test ❱ Screw/Ferrule replacement ❱ Changing check valves, in-line filters and seals

Who Should AttendUsers of the 2690/2695 separations module who want to understand the operation of the 2695 separations module and perform basic troubleshooting on their system.

PrerequisitesBasic knowledge of HPLC.


66


Alliance 2695/2795 Operation and Maintenance

Language: Danish, Dutch, English, Finnish, French, SwedishLocation: Austria, Belgium, Denmark, Finland, France, The Netherlands, Norway, Sweden

Ref.: WAT038306 – 2 days

Course Description This course instructs users in the operation, maintenance and trouble shooting of Waters 2695/2795 Separations Module. Emphasis is on solvent and sample management technology. This course includes lectures followed by practical sessions that reinforce the lecture material. After completion of this course, attendees should be able to identify and diagnose instrumentation issues, to keep their Alliance HPLC System running at the highest level of performance.

Topics Covered ❱ Sample and Solvent Management Technology ❱ Instrument configuration ❱ Direct functions ❱ Creating separation methods ❱ Creating sample sets and templates ❱ Diagnostics ❱ Hands on: Day-to-day maintenance and troubleshooting

Who Should AttendThis course is designed for individuals who are responsible for the routine performance maintenance of Waters 2695/2795 Separations Module.

PrerequisitesNone




Alliance 2795 System Operation and Maintenance


Ref.: 750000214 – 2 days

Course DescriptionThe course describes in detail the operation of the Separations Module 2790/2795 and develops procedures for Alliance to use the system in an optimized way. T he components of the separations module, the steps of initiation, parameter definition and verification of diagnoses are being developed to understand the operation of the device and to benefit from its analytical performance. It addresses the theoretical and practical aspects.

Topics Covered ❱ The principles of operation of the module 2790/2795 ❱ Solvent Manager ❱ Handler samples ❱ The different modes of initiation ❱ “Dry premium, premium wet” ❱ Creation of boot methods: automatic ❱ Mode of operation and optimization of use ❱ The mixing valve (GPV) ❱ Placement of solvents ❱ Test and verification of solenoid ❱ The method of type “default” ❱ Study of the parameters’ CD ratio “and” stroke volume “ ❱ Testing mixtures and baseline bottom UV ❱ Gradient 0 to 100% ❱ Premix and gradient of 10 to 90% ❱ Changing values and importance of the parameter “stroke volume” ❱ Calculation of the volume before column (“dwell volume”) ❱ Injection mode and normal gradient based Advanced ❱ The valves ❱ The different models ❱ The precautions ❱ Cleaning of the injection needle ❱ Study of solvent and duration parameters ❱ Purging of the syringe ❱ How to remove air bubbles? ❱ The configuration of the syringe ❱ Volume and speed of sampling

Who Should Attend The course is for system users wishing to use the Alliance for Separation Module 2790/2795 under optimal conditions.

PrerequisitesSpecify the configuration of your Alliance System during registration.


68


Maintenance School – 717Plus automatic injector/2707



Course DescriptionThe course describes a methodology for the use, care, maintenance and study of malfunction of the autosampler 717Plus or 2707. It addresses the theoretical and practical aspects.

Topics Covered ❱ Principles of operation of the automatic injector ❱ Purge cycle ❱ Checking the compressibility ❱ Injection cycle ❱ Calibration sequence ❱ Operation and dismantling of the automatic injector ❱ Fluidic circuit – Mechanical ❱ Electronic the automatic injector ❱ Tests point and diagnostics

PrerequisitesSpecify the configuration of your HPLC system during registration.

Who Should Attend The course is designed for users of the autosampler 717Plus or 2707.




Maintenance School – Detection System


Ref.: 750000462 – 1 day

Course DescriptionThe course describes a methodology for the use, care, maintenance and study of malfunction detectors HPLC. It addresses the theoretical and practical aspects.

Topics Covered ❱ Principle of different detection modes ❱ Dismantling – Relamping and optical alignment ❱ Tests – Accuracy of wavelength and linearity of the detector ❱ Electronic settings

Who Should Attend The course is designed for users of Waters HPLC detectors.



70


Maintenance School – Pumping System


Ref.: WAT038318 – 1 day

Course DescriptionThe course describes a methodology for the use, care, maintenance and study of malfunction of HPLC pumps. It addresses the theoretical and practical aspects.

Topics Covered ❱ Principles of operation ❱ Description ❱ Dismantling and testing


Who Should Attend The course is designed for users of conventional HPLC pumps.




Qualification School on LC System


Ref.: 750000271 – 1 day

Course DescriptionThe course describes the methodology for the qualification of your conventional HPLC system: pump, automatic injector, detector and software. It takes place on the client hardware and through the documents.

Topics covered ❱ Validations workbook - Conventions overview ❱ 2487, 486 installation qualification ❱ 2487, 486 qualification of maintenance ❱ Qualification tool kit ❱ 2487, 486 operational qualification ❱ Pump operational qualification ❱ Autosampler 717 operational qualification ❱ Installation qualification and maintenance for Millennium and Empower ❱ Operational qualification Empower or MillenniumAQT (IQ-OQ-MP) for Millennium, Empower or Empower 2 ❱ 2996, 996 Qualification of maintenance ❱ 2996, 996 Operational qualification ❱ 2695, 2690 Installation qualification and maintenance ❱ 2695, 2690 Operational qualification ❱ Performance qualification system ❱ End performance qualification510-515•Installation qualification•Qualification of maintenance•Operational qualification•Questions and revisions•Knowledge test

Who should attendThe course is intended for users of Waters HPLC systems.

PrerequisitesSpecify the configuration of your HPLC system when registering.


72


Troubleshooting and Maintenance of HPLC Systems

Language: SpanishLocation: Spain


Course DescriptionThis course is to provide a practical vision about diagnosing problems that can arise in a chromatographic system and its solution, either a problem with the separation or a malfunction of a particular module. The course includes the following modules: Pumps (510, 515, and 600), injector (717) and detectors (UV, Fluorescent and RI). In the afternoon the maintenance of the modules is implemented in the laboratory.

Topics Covered ❱ General HPLC troubleshooting ❱ Pump maintenance ❱ Inlet/outlet valves replaced ❱ Pump seals replaced ❱ Pistons replaced ❱ Injector maintenance ❱ Replacement sealing rings ❱ Syringe replaced ❱ Detector maintenance ❱ Lamp ❱ Cell cleaning

Who Should AttendThe course is designed for users of Waters modular HPLC systems, who wish to maintain the equipment and the basic problems to be identified.





Waters Educational Services are Just Around the Corner

Waters Educational Services courses are available around the world. Our major training centers are:n Waters World Wide Training Center –

Milford, MA, U.S.A.

n Waters European Headquarters and Training Center – Saint-Quentin-en-Yvelines, France

n Waters Asian Training Center – Singapore

n Waters World Wide Mass Spectrometry Center of Excellence – Manchester, United Kingdom

n Waters North American Mass Spectrometry Center – Beverly, MA, U.S.A.

n Waters HPLC-Mass Spectrometry Center West Coast – Pleasanton, CA, U.S.A.

We also offer courses at each of our offices, with additional training centers in China, India, Japan, and Puerto Rico. Each year, more than 6,000 students visit our training sites in over 30 countries.

To find out all the locations near your area, go to

www.waters.com/courses and select a country and the courses of your choice. It’s that easy.

74

[ MASS SPECTROMETRY ]

75

ACQUITY QDa with Empower

Language: Danish, English, Finnish, German, Italian, Swedish Location: Denmark, Finland, Norway, Sweden, Switzerland, United Kingdom

Ref.: 750000833 – 2 days

Course Description T his course introduces you to the ACQUITY QDa Detector Hardware and operating principles in an Empower Software environment. Students are shown ACQUITY QDa Detector specific topics within the Empower Software, such as instrument method settings and working with mass spectral data in the review window. Lab exercises are performed to practice and reinforce Empower MS data processing concepts needed to become successful with the QDa Detector and Empower Software.

Topics Covered ❱ ACQUITY QDa Detector principles and hardware ❱ Preparing to run•ACQUITY QDa Detector Console•ACQUITY QDa Detector instrument method settings

❱ Empower review 3D window overview•Toolbar functions•Table properties•Extracting chromatograms•Extracting spectra•Spectrum plot properties•3D view•Developing a processing method for 3D data

❱ Mass analysis window (for Empower 3 FR2)•Extracting a channel•MS spectra extraction•Mass analysis window toolbar•Mass analysis window view properties

❱ User maintenance•Source part replacement/cleaning•Capillary replacement

Who Should AttendEmpower software users who want to rapidly learn the capabilities of the ACQUITY QDa Detector.

PrerequisitesAttendee must be familiar with Empower Software using the Pro Interface. Knowing how to work with 2-dimensional chromatography data in Empower Software as well as an understanding of foundational LC-MS principles is helpful.


76


Characterization of Peptides and Proteins by LC-MS

Language: EnglishLocation: Denmark, Sweden

Ref.: 750000467 – 2 days

Course DescriptionThis course is designed for people that need to know how LC-MS can be used for characterization of peptides and proteins. The course consists of lectures and exercises.

Topics Covered ❱ Introduction to MS analysis of peptides and proteins ❱ Practical aspects of ESI-MS and LC-MS analysis of peptides and proteins ❱ Data processing and information from mass spectra ❱ Instrumentation and strategies for peptide sequencing ❱ Fragmentation of peptides in MS-MS, fundamentals and examples ❱ Interpretation of MS-MS spectra of peptides ❱ Software tools for the interpretation of MS-MS spectra ❱ Strategies and perspectives in peptides and protein characterization and Proteomics™

Who Should AttendEveryone that wants an introduction to the field of characterization of peptides and proteins by LC-MS.

PrerequisitesBasic knowledge of HPLC and LC-MS.




Fundamentals of LC-MS

Language: Danish, English, Spanish, SwedishLocation: Denmark, Finland, Norway, Spain, Sweden, United Kingdom

Ref.: 750000167 – 1 day

Course Description “Fundamentals of LC-MS” course provides information to make an effective transition from traditional HPLC detectors to MS detectors. The course covers relevant current ionization techniques and mass analyzers. Consideration is also given to converting existing HPLC methods for use with MS detectors. Practical examples guide the user on how to modify the HPLC separation to make them suitable for MS detection.

Topics Covered ❱ Mass spectrometry overview ❱ Atmospheric pressure ionization fundamentals ❱ Selecting an appropriate MS ionization technique ❱ Overview of mass analyzers ❱ Liquid Chromatography Considerations ❱ Conversion of established HPLC methods for use with an MS detector

Who Should AttendIndividuals with no or little LC-MS knowledge that needs to learn the fundamental principles of LC-MS, or persons responsible for developing new, or transferring existing, HPLC methods for use with an MS detector. Current practitioners of LC-MS may also benefit if their understanding of the technique is limited and they have had no formal training in LC-MS techniques.

PrerequisitesAttendees should be familiar with the basic principles of HPLC.


78


Interpretation of MS and MS/MS Spectra

Language: EnglishLocation: Denmark, Finland, Norway, Sweden, United Kingdom

Ref.: 750000466 – 2 days

Course Description The aim of this course is to study the fragmentation of positively and negatively charged even-electron ions of small molecules during in-source CID or MS/MS in triple-quadrupole, ion-trap, and quadrupole time-of-flight hybrid systems. The emphasis is on spectrum interpretation rather than on fragmentation mechanisms. In addition to lectures and ample time for questions and discussion, the course provides exercises in order to practice spectral interpretation.

Topics Covered ❱ Introduction to MS/MS ❱ Theoretical aspects of collision induced dissociation, CID ❱ Fragmentation techniques ❱ In-source CID ❱ Triple quadrupole ❱ Ion-trap ❱ Quadropole-Tof ❱ General aspects of fragmentation of even-electron positive ions ❱ Fragmentation of different compound classes, illustrated with typical examples ❱ Fragmentation of even-electron negative ions ❱ Strategies in structure elucidation.

Who Should AttendThis course is designed for individuals, who are new users to LC-MS or MS/MS want to learn how to interpret mass spectra, or existing users who want to supplement their skills. This course is for all LC-MS and MS/MS and is not specific for users of Waters/Micromass® MS Instruments.

Prerequisites6 months experience with LC-MS or MS/MS.




LC-MS/MS School


Ref.: 750000452 – 3 days

Course DescriptionT he user training is an intensive hands-on course that provides participants with the skills to exploit the potential of a triple-quadrupole LC-MS/MS system optimally. It is suitable mainly for new employees who are trained to an existing LC-MS/MS system, but also for experienced users who want to brush up your skills in mass spectrometry. The limited number of participants makes it possible to discuss problems in the everyday user in detail and applied in practical exercises. Each participant has a laptop available.

Topics Covered ❱ Theory of modern mass spectrometry (ionization and device types) ❱ Atmospheric pressure ionization (API) – Electrospray and APCI ❱ Structure and principle of a triple quadrupole mass spectrometer ❱ Rules for Use/fault detection and removal ❱ Calibration of the mass scale of a tandem mass spectrometer* ❱ Scanning techniques* the tandem mass spectrometer ❱ Make measurements to quantify*• Position dilution series/measure*

❱ Evaluation of the quantification measurement with the application manager QuanLynx ❱ Another idea MassLynx Application Managers•OpenLynx, MetaboLynx, TargetLynx

Equipment maintenance and troubleshooting* * The practical work done in the laboratory on a tandem quadrupole mass spectrometer.

PrerequisitesParticipation in an initial instruction on a Waters LC-MS/MS system or at least 6 weeks experience in dealing with other systems Waters LC-MS/MS.

Course NotesAll Participants will receive the complete training material and a Certificate of Attendance.

80


MALDI SYNAPT G2-S HDMS Operation

Language: English Location: Waters European Training Center in Manchester (United Kingdom)

Ref.: 750000656 – 3 days

Course DescriptionA comprehensive MALDI SYNAPT™ G2-S HDMS® operation training course for biopharmaceutical applications. Hands-on MassLynx training, including laboratory sessions, enhances and reinforces lecture material. Laboratory sessions offer the opportunity to work with other attendees and Waters application experts on Waters MALDI SYNAPT G2-S.

Topics Covered ❱ Overview of MALDI ❱ Tof Accurate Mass Overview•Tof theory•Use of accurate mass data

❱ Instrument optimization, data acquisition•SYNAPT G2-S Instrument schematics•Tuning and calibration•MS and MS/MS data acquisition

❱ Routine maintenance ❱ MassLynx Software overview ❱ MALDI Sample Preparation ❱ HDMS – acquisition of data using ion mobility•DriftScope™

Daily EventsDefined lab exercises to reinforce the skills taught.

Who Should AttendPersonnel responsible for operation of MALDI SYNAPT G2-S.


Course Notes Each attendee will receive a course manual to keep for future reference and a Certificate of Attendance.



MALDI Imaging Operation


Ref.: 750000757 – 3 days

Course DescriptionA comprehensive MALDI SYNAPT G2-S operation training course for Imaging applications. Hands-on MassLynx, and High Definition Imaging® (HDI®) imaging software training, including laboratory sessions enhances and reinforces lecture material. Laboratory sessions offer the opportunity to work with other attendees and Waters application experts on the MALDI SYNAPT G2-S.

Topics Covered ❱ Introduction•Overview of MALDI imaging workflows using the MALDI SYNAPT G2-S and HDI imaging software

❱ Sample preparation•Manual spray coating•SunCollect MALDI-spotter (Sunchrom) spray coating

❱ Instrument tuning for MALDI imaging•Quad profile•Calibration•Ion mobility

❱ Data acquisition•Experimental set-up•Untargeted imaging workflows (MS, ion mobility-MS and MSE acquisitions)•Targeted imaging workflows (MS/MS and ion mobility MS/MS acquisitions)•Lockmass set-up

❱ HDI imaging software •Pattern creation•Processing•Image analysis


Who Should AttendPersonnel responsible for operation of MALDI SYNAPT G2-S.



82


LC-MS Course at Waters facilities

Language: Français Location: Belgium

Ref.: 750000889 – 2 days

Overview The user training is an intensive hands-on course that provides participants with the skills to exploit the potential of a triple-quadrupole LC-MS/MS system optimally. It is suitable mainly for new employees who are trained to an existing LC-MS/MS system, but also for experienced users who want to brush up your skills in mass spectrometry. T he limited number of participants makes it possible to discuss problems in the everyday user in detail and applied in practical exercises.

Details ❱ Theory of modern mass spectrometry (ionization and device types) ❱ Atmospheric pressure ionization (API) – Electrospray and APCI ❱ Structure and principle of a triple quadrupole mass spectrometer ❱ Rules for Use / fault detection and removal ❱ Calibration of the mass scale of a tandem mass spectrometer* ❱ Scanning techniques* the tandem mass spectrometer ❱ Make measurements to quantify*•Position dilution series / measure*

❱ Evaluation of the quantification measurement with the application manager QuanLynx, TargetLynx * The practical work done in the laboratory on a tandem quadrupole mass spectrometer.

Prerequisites Participation in an initial instruction on a Waters LC-MS/MS system or at least 6 weeks experience in dealing with other systems Waters LC-MS/MS.

Recommendations System configuration (LC/MS or LC/MS/MS) should be indicated for registration.




nanoACQUITY UPLC Techniques and Operation


Ref.: 750000470 – 2 days

Course Description This two-day training course is designed for the nanoACQUITY® UPLC System users to cover the chemistry, operating principles and maintenance.

Topics Covered ❱ NanoFlow™ Chromatography and benefits of 1.7 µm particles ❱ Introduction to nanoACQUITY UPLC Hardware and design features ❱ Full description of nanoACQUITY UPLC flowpath and possible valve configurations ❱ Using the nanoACQUITY UPLC Console Software for system startup, including priming the Binary Solvent Manager

and Sample Manager as well as calibrating the Sample Manager ❱ Column plumbing, leak testing and column equilibration ❱ Setup, acquisition and evaluation of over night test runs ❱ General troubleshooting techniques, including tips and tricks ❱ General discussion forum and Q&A’s

Who Should AttendThis course is for individuals who wish to understand the chemistry, operating principles and user maintenance of the nanoACQUITY UPLC System.

PrerequisitesAttendees should be familiar with the basic principles of HPLC and MS.


84


Purification of Compounds using FractionLynx (Mass Detector)


Ref.: 750000307 – 4 days

Course Description Operators training course designed to enhance understanding and use of features of the Autopurification™ Instrument and FractionLynx Software. It also provides an overview of the MassLynx Software. Predominantly laboratory-based training sessions to enhance course materials as well as provide an opportunity to interact with other attendees. Defined lab sessions to reinforce taught topic.

Topics Covered ❱ MS reminder – ionisation types, MS instrument schematics, tune page overview, MS tuning and calibration theoretical

overview, routine MS maintenance ❱ Preparative LC concepts and guidelines – basic column chemistry, loading and scale-up considerations, resolution, speed

and recovery considerations, special techniques such as at-column-dilution, solid-phase fraction collection, AutoPurify™, waste collection, column regeneration etc. ❱ Hardware configuration – system hardware configuration overview, system plumbing, system pressure setting and

adjustment (lab based training) ❱ LC instrument setting/Sample list building – comprehensive overview of MassLynx Software, instrument set-up, writing

data acquisition methods, writing and editing sample list (lab based training) ❱ Fraction collection set-up – comprehensive overview of FractionLynx software, fractioncollection instrument set-up

and configuration, loading configurations, manual/emergency control, bed layout visualization, collection modes (lab based training) ❱ Fraction method/Fraction trigger overview – writing fraction trigger methods, comprehensive overview of fraction method

settings, MIT settings, time slicing, mixed triggers, secondary triggers etc (lab based training) ❱ Single sample and Batch processing – manual data processing, fraction display parameters, writing autopurify methods

for batch processing (lab based training) ❱ Reporting – generating electronic report i.e. browser report and editing, paper report generation – full and summary

report (lab based training) ❱ Hands-on session – sample analysis to illustrate analytical scouting run, purification experiment to illustrate collection

by mass and wavelength. Use fraction collection simulation software feature to illustrate various trigger modifications, MIT settings and finally process acquired data to illustrate browser and paper report settings ❱ Automation: The function AutoPurify

Who Should AttendOperators or personnel responsible for autopurification systems.

PrerequisitesMinimum of 3 months experience running the system.

Courses NotesEach attendee will receive a course manual to keep for future reference and a Certificate of Attendance.



Purification of Compounds using FractionLynx (UV Detector)


Ref.: 750000433 – 3 days

Course Description Operators training course designed to enhance understanding and use of features of the Autopurification Instrument and FractionLynx Software. It also provides an overview of the MassLynx Software. Predominantly laboratory-based training sessions to enhance course materials as well as provide an opportunity to interact with other attendees. Defined lab sessions to reinforce taught topics.

Topics Covered ❱ Preparative LC concepts and guidelines – basic column chemistry, loading and scale-up considerations, resolution, speed

and recovery considerations, special techniques such as at-column-dilution, waste collection, column regeneration etc. ❱ Hardware configuration – system hardware configuration overview, system plumbing, system pressure setting

and adjustment (lab based training) ❱ LC instrument setting/Sample list building – comprehensive overview of MassLynx Software, instrument set-up,

writing data acquisition methods, writing and editing sample list (lab based training) ❱ Fraction collection set-up – comprehensive overview of FractionLynx Software, fraction collection instrument set-up

and configuration, loading configurations, manual/emergency control, bed layout visualization, collection modes (lab based training) ❱ Fraction method/Fraction trigger overview – writing fraction trigger methods, comprehensive overview o f fraction

method settings, MIT settings, time slicing, mixed triggers, secondary triggers etc (lab based training) ❱ Single sample and batch processing – manual data processing, fraction display parameters, ❱ Reporting – generating electronic report i.e. browser report and editing, paper report generation – full and summary

report (lab based training) ❱ Hands-on session purification experiment to illustrate collection by wavelength. Use fraction collection simulation

software feature to illustrate various trigger modifications, MIT settings and finally process acquired data to illustrate browser and paper report settings.

Who Should AttendOperators or personnel responsible for autopurification systems.

PrerequisitesMinimum of 3 months experience running the system.

Courses NotesEach attendee will receive a course manual to keep for future reference and a Certificate of Attendance.

86


Quantification of Peptides and Proteins by LC-MS/MS

Language: English, SwedishLocation: Sweden

Ref.: 750000649 – 2 days

Course DescriptionA 2-day practical training course covering development of methods for quantification of peptides and proteins with LC-MS/MS.

Topics Covered ❱ Proteins and Peptides theory:•Characteristics of peptides•Differences from small molecules•Differences between peptides

❱ Strategies for method development: MS•Triple quad theory•Setting up MRM transitions for quantification•Enzymatic digest for proteins•Selecting peptide to quantify LC•Mobile phase selection•pH•Temperatures

❱ Sample Prep:•SPE, protein precipitation or LL extraction?•Choice of sample prep conditions

❱ Lab sessions:•MS method development for peptides and proteins•LC method development for peptides and proteins

For the practical part we will use UPLC and Tandem Quadrupole MS

Daily eventsTheory lessons and practice in the Lab.

Who Should AttendAnalysts who need knowledge of quantification of peptides and proteins with LC-MS/MS.

Prerequisites Attendees need previous experience of LC-MS.




SYNAPT G2-Si Biopharmaceutical


Ref.: Please check our website, www.waters.com/courses – 5 days

Course DescriptionA comprehensive ACQUITY UPLC/SYNAPT G2-Si operation training course for biopharmaceutical applications. Hands-on MassLynx and BiopharmaLynx training, including laboratory sessions, enhances and reinforces lecture material. Laboratory sessions offer the opportunity to work with other attendees and Waters application experts on Waters SYNAPT G2-Si.

Topics Covered ❱ Tof accurate mass overview•Tof theory•Use of accurate mass data

❱ Instrument optimization, data acquisition•SYNAPT G2-Si instrument schematics•Electrospray ionization•LockSpray™ Ion Source•IntelliStart™•Tuning and calibration•MS and MS/MS data acquisition•MSE data acquisition

❱ Routine maintenance ❱ MassLynx software overview ❱ UPLC-MS Interfacing ❱ BiopharmaLynx•Intact protein spectrum denconvolution with MaxEnt™

❱ Sample preparation (de-salting etc.). ❱ HDMS – acquisition of data using ion mobility•DriftScope


Who Should AttendPersonnel responsible for biopharmaceutical applications using SYNAPT G2-Si.



88


SYNAPT G2-Si (NanoFlow Proteomics)



Course DescriptionA comprehensive nanoACQUITY UPLC/SYNAPT G2-Si operation training course for proteomics applications. Hands-on proteomics workflow training, including laboratory sessions and IdentityE, enhances and reinforces lecture material. Laboratory sessions offer the opportunity to work with other attendees and Waters application experts on Waters SYNAPT G2-Si.


❱ Instrument optimization, data acquisition•SYNAPT G2-Si instrument schematics•Electrospray ionization•NanoLockSpray™ Ion Source•Tuning and calibration•MS and MS/MS data acquisition (including DDA)•MSE data acquisition

❱ Routine maintenance ❱ MassLynx software overview ❱ nanoACQUITY UPLC-MS Interfacing•NanoFlow Electrospray

❱ Sample Preparation ❱ Database searching•Introduction to databanks•ProteinLynx Global SERVER™•IdentityE (basic introduction)*

*This course gives a basic introduction to IdentityE. A dedicated course is available for full training on IdentityE and ExpressionE


Who Should AttendPersonnel responsible for proteomics applications using nanoACQUITY UPLC coupled to SYNAPT G2-Si.





SYNAPT G2-Si (Small Molecules)



Course DescriptionA comprehensive ACQUITY UPLC/SYNAPT G2-Si operation training course for small molecule applications. Hands-on MassLynx training, including laboratory sessions, enhances and reinforces lecture material. Laboratory sessions offer the opportunity to work with other attendees and Waters application experts on Waters SYNAPT G2-Si.


❱ Instrument optimization, data acquisition•SYNAPT G2-Si instrument schematics•Electrospray ionization•LockSpray Ion source•IntelliStart•Tuning and calibration•MS and MS/MS data acquisition•MSE data acquisition

❱ Routine maintenance ❱ MassLynx Software overview ❱ Basic training in:•MetaboLynx – metabolite ID software•MarkerLynx – metabonomics software•ChromaLynx – screening software•MassFragment

*course content depends on attendees requirements ❱ UPLC-MS Interfacing ❱ HDMS – acquisition of data using ion mobility•DriftScope


Who Should AttendPersonnel responsible for small molecule applications using SYNAPT G2-Si.



90


Xevo G2-XS Tof/Q-Tof (Biopharmaceutical)



Course DescriptionA comprehensive ACQUITY Xevo® G2-XS Q-Tof and Xevo G2-XS Q-Tof operation training course for small molecule applications. Hands-on MassLynx training, including laboratory sessions, enhances and reinforces lecture material. Laboratory sessions offer the opportunity to work with other attendees and Waters application experts on Waters Xevo G2-XS Tof/Q-Tof.

Topics Covered ❱ Tof accurate mass overview•Tof theory•Using accurate mass data

❱ Instrument optimization, data acquisition•Xevo G2-XS Tof/Q-Tof Hardware overview•Electrospray ionization•LockSpray ion source•IntelliStart•Tuning and calibration•MS and MS/MS data acquisition•MSE data acquisition

❱ Routine maintenance ❱ MassLynx Software overview ❱ UPLC-MS Interfacing ❱ BiopharmaLynx•Intact protein spectrum denconvolution with MaxEnt

❱ Sample preparation (de-salting etc.).


Who Should AttendPersonnel responsible for biopharmaceutical applications using Xevo G2-XS Tof or G2-XS Q-Tof.





Xevo G2-XS Tof/Q-Tof (NanoFlow Proteomics)



Course DescriptionA comprehensive nanoACQUITY UPLC Xevo G2-XS Q-Tof and Xevo G2-XS Q-Tof operation training course for proteomics applications. Hands-on proteomics workflow training, including laboratory sessions and IdentityE, enhances and reinforces lecture material. Laboratory sessions offer the opportunity to work with other attendees and Waters application experts on Waters Xevo G2-XS Tof Q-Tof.


❱ Instrument optimization, data acquisition•Xevo G2-XS Tof/Q-Tof Hardware overview•Electrospray ionization•LockSpray Ion Source•IntelliStart•Tuning and calibration•MS and MS/MS data acquisition•MSE data acquisition

❱ Routine maintenance ❱ MassLynx Software overview ❱ nanoACQUITY UPLC-MS Interfacing•NanoFlow Electrospray

❱ Sample preparation ❱ Database searching•Introduction to databanks.•ProteinLynx Global SERVER•IdentityE (basic introduction)* * This course gives a basic introduction to IdentityE. A dedicated course is available for full training on IdentityE and ExpressionE.


Who Should AttendPersonnel responsible for proteomics applications using nanoACQUITY coupled to Xevo G2-XS Tof or Xevo G2-XS Q-Tof.

PrerequisitesAttendees should have a minimum of 6 weeks experience operating the instrument. Course NotesEach attendee will receive a course manual to keep for future reference and a Certificate of Attendance.

92


Xevo G2-XS Tof/Q-Tof (Small Molecules)



Course DescriptionA comprehensive ACQUITY/Xevo G2-XS Q-Tof and Xevo G2-XS Q-Tof operation training course for small molecule applications. Hands-on MassLynx training, including laboratory sessions, enhances and reinforces lecture material. Laboratory sessions offer the opportunity to work with other attendees and Waters application experts on Waters Xevo G2-XS Tof/Q-Tof.


❱ Instrument optimization, data acquisition•Xevo G2-XS Tof/Q-Tof Hardware overview•Electrospray ionization•LockSpray Ion Source•IntelliStart•Tuning and calibration•MS and MS/MS data acquisition•MSE data acquisition

❱ Routine maintenance ❱ MassLynx Software overview ❱ Basic training in*:•MetaboLynx – Metabolite ID Software•MarkerLynx – Metabonomics software•ChromaLynx – Screening software•MassFragment *course content depends on attendees requirements

❱ UPLC-MS Interfacing

Daily Events:Defined lab exercises to reinforce the skills taught.

Who Should AttendPersonnel responsible for small molecule applications using Xevo G2-XS Tof or G2-XS Q-Tof.





Xevo G2-XS Tof/Q-Tof UNIFI (Biopharmaceutical)



Course DescriptionA comprehensive ACQUITY/Xevo G2-XS Q-Tof and Xevo G2-XS Q-Tof operation training course for small molecule applications. Hands-on UNIFI® training, including laboratory sessions that enhance and reinforce the lecture material. Laboratory sessions offer the opportunity to work with other attendees and Waters application experts on Waters Xevo G2-XS Tof/Q-Tof.

Topics Covered ❱ Tof accurate mass overview•Tof theory•Using accurate mass da

❱ Instrument optimization, data acquisition•Xevo G2-XS Tof/Q-Tof Hardware overview•Electrospray ionization•LockSpray Ion Source•Tuning and calibration•MS and MS/MS data acquisition•MSE data acquisition

❱ Routine maintenance ❱ UNIFI Software overview•focusing on biopharmaceutical applications

❱ UPLC-MS Interfacing ❱ Sample Preparation (de-salting etc.).


Who Should AttendPersonnel responsible for biopharmaceutical applications using Xevo G2-XS Tof or G2-XS Q-Tof.



94


Xevo G2-XS Tof/Q-Tof UNIFI (Small molecules)



Course DescriptionA comprehensive ACQUITY/Xevo G2-XS Q-Tof and Xevo G2-XS Q-Tof operation training course for small molecule applications. Hands-on UNIFI Training, including laboratory sessions which enhance and reinforce the lecture material. Laboratory sessions offer the opportunity to work with other attendees and Waters application experts on the Xevo G2-XS Tof/Q-Tof.


❱ Instrument optimization, data acquisition•Xevo G2-XS Tof/Q-Tof Hardware overview•Electrospray ionization•LockSpray Ion Source•Tuning and calibration•MS and MS/MS data acquisition•MSE data acquisition

❱ Routine maintenance ❱ UNIFI Software overview

focusing on small molecule applications ❱ UPLC-MS Interfacing


Who Should AttendPersonnel responsible for small molecule applications using Xevo G2-XS Tof or G2-XS Q-Tof.





Xevo TQD Operation and Maintenance

Language: English, Germany, FrenchLocation: France, Germany, United Kingdom

Ref.: 750000611 – 4 days

Course Description Comprehensive Xevo TQD operation training course for small molecule applications. Hands-on MassLynx Software training, in addition to laboratory sessions, enhances and reinforces lecture material. Laboratory sessions offer the opportunity to work with other attendees on Xevo TQD Systems. Coverage of advanced topics, software options and hardware options dependent on participant interest and available time.

Topics Covered ❱ Xevo TQD Instrument overview ❱ Atmospheric Pressure Ionization (API) Fundamentals ❱ Hardware ❱ Using the instrument console ❱ ACQUITY monitoring and control. ❱ IntelliStart ❱ Sample tune ❱ Develop methods ❱ Calibration ❱ MassLynx overview ❱ Creating ACQUITY Methods ❱ Creating MS and MS/MS Methods ❱ Creating sample lists ❱ Data acquisition ❱ Data processing ❱ Quantification with TargetLynx and QUANPEDIA™ ❱ Xevo TQD maintenance ❱ Laboratory sessions ❱ Tuning and calibration ❱ Data acquisition ❱ Quantification ❱ Maintenance



96


Xevo TQ-S Operation and Maintenance (NanoFlow Proteomics)

Language: English Location: United Kingdom

Ref.: 750000550 – 4 days

Course Description Comprehensive nanoACQUITY UPLC/Xevo TQ-S operation training course for quantification of protein/peptides using nanoESI on a tandem quadrupole. Hands-on MassLynx Software training, in addition to laboratory sessions, enhances and reinforces lecture material. Laboratory sessions offer the opportunity to work with other attendees on Xevo TQ-S Systems. Coverage of advanced topics, software options and hardware options dependent on participant interest and available time.

Topics Covered ❱ Xevo TQ-S Instrument overview ❱ Atmospheric Pressure Ionization (API) fundamentals ❱ Hardware ❱ Using the instrument console•nanoACQUITY UPLC monitoring and control•Tuning and calibration•Method development

❱ MassLynx overview•Creating nanoACQUITY UPLC methods•Creating MS and MS/MS Methods •Creating sample lists•Use of verify•Data acquisition•Data processing•Quantification with TargetLynx and QUANPEDIA

❱ Xevo TQ MS maintenance ❱ Laboratory sessions•Tuning and calibration•Data acquisition•Quantification•Maintenance

Who Should AttendPersonnel responsible for proteomic applications using nanoACQUITY UPLC coupled with Xevo TQ-S.





Xevo TQ-S and Xevo TQ-S micro

Language: English, German, FrenchLocation: France, Germany, United Kingdom

Ref.: 750000549 – 4 days

Course Description Comprehensive Xevo TQ-S operation training course for small molecule applications. Hands-on MassLynx Software training, in addition to laboratory sessions, enhances, and reinforces lecture material. Laboratory sessions offer the opportunity to work with other attendees on Xevo TQ-S Systems. Coverage of advanced topics, software options and hardware options dependent on participant interest and available time.

Topics Covered ❱ Xevo TQ-S instrument overview ❱ Atmospheric Pressure Ionization (API) Fundamentals ❱ Hardware ❱ Using the instrument console•ACQUITY monitoring and control•IntelliStart•Sample tune•Develop methods•Calibration

❱ MassLynx overview•Creating ACQUITY methods•Creating MS and MS/MS methods•Creating sample lists•Data acquisition•Data processing•Quantification with TargetLynx and QUANPEDIA

❱ Xevo TQ MS Maintenance ❱ Laboratory sessions•Tuning and calibration•Data acquisition•Quantification•Maintenance

Who Should AttendPersonnel responsible for small molecules applications using Xevo TQ-S.



98


Xevo TQ-S Micro Operation and Maintenance

Language: English, German, FrenchLocation: France, Germany, United Kingdom


Course Description Comprehensive Xevo TQ-S Micro operation training course as it relates to small molecule applications. Hands-on MassLynx Software training, in addition to laboratory sessions, enhances and reinforces lecture material. Laboratory sessions offer the opportunity to work with other attendees on Xevo TQ-S Micro Systems. Coverage of advanced topics, software options and hardware options dependent on participant interest and available time.

Topics Covered ❱ Xevo TQ-S Micro Instrument overview ❱ Atmospheric Pressure Ionization (API) fundamentals ❱ Hardware ❱ Using the instrument console•ACQUITY monitoring and control•IntelliStart•Sample tune•Develop methods•Calibration

❱ MassLynx overview•Creating ACQUITY methods•Creating MS and MS/MS methods•Creating sample lists•Data acquisition•Data processing

❱ Xevo TQ MS Maintenance ❱ Laboratory sessions•Tuning and calibration•Data acquisition•Quantitation•Maintenance

Who Should AttendPersonnel responsible for using Xevo TQ-S Micro.





Xevo TQ-S UNIFI (Bioanalysis)


Ref.: 750000655 – 4 days

Course DescriptionComprehensive Xevo TQ-S operation training course for small molecule applications. Hands-on UNIFI Software training, in addition to laboratory sessions, enhances and reinforces lecture material. Laboratory sessions offer the opportunity to work with other attendees on Xevo TQ-S Systems. Coverage of advanced topics, software options and hardware options dependent on participant interest and available time.

Topics Covered ❱ Xevo TQ-S Instrument overview ❱ Atmospheric Pressure Ionization (API) Fundamentals ❱ Hardware ❱ Using the instrument console ❱ ACQUITY monitoring and control. ❱ Automated compound optimisation ❱ Sample tune ❱ Develop analysis methods/ Method development ❱ Calibration ❱ UNIFI overview ❱ Creating an Analysis Method ❱ Creating an analysis ❱ Data acquisition ❱ Data processing ❱ Quantification with UNIFI ❱ Xevo TQ-S Maintenance ❱ Laboratory sessions ❱ Tuning and calibration ❱ Data acquisition ❱ Quantification ❱ Maintenance



100


101

[ NOTES ]

[ GENERAL CHROMATOGRAPHY ]

103

HPLC Fundamentals and Troubleshooting

Language: SpanishLocation: Spain

Ref.: 750000502 – 1 day

Course DescriptionThe training, which is designed for beginners with a maximum of one year experience gives HPLC, the basic principles of liquid chromatography (HPLC), which are necessary for competent decisions in modern laboratory work. Starting with an understandable explanation of the different types of chromatography and the different types of chromatographic detectors parameters such as resolution, plate number, capacity factor, selectivity, or tailing are discussed in detail. A separate section deals with the various reversed-phase materials and explained in a surprisingly simple way, how can the resulting differences in selectivity for use a separation problem.

Topics Covered ❱ Principles and terminology of the HPLC ❱ Chromatographic separation mechanisms ❱ Chromatographic applications (demonstrations)

PrerequisitesNone.

Course NotesAll Participants will receive the complete training material and a Certificate of Attendance.

104


Concepts of Sample Preparation with SPE (Solid-Phase Extraction)

Language: GermanLocation: Austria

Ref.: 750000481 – 1 day

Course descriptionThe training, which was designed specifically for chromatographers, conveys the basic principles of solid phase extraction (SPE) as a powerful variant in sample preparation. In recent years this technology has gained popularity, which is directly explained by the increasing importance of analyzing costs and the increase in requirements of sensitivity, accuracy, precision, and sample throughput in modern analytical laboratories. Using detailed work records a number of applications are presented, which leverage the power of the latest developments in the SPE. These techniques can be easily applied to existing method development protocols. Lastly, SPE experiments will be used to demonstrate the different strategies for sample preparation.

Topics Covered ❱ Fundamentals and theory (including alternative sample preparation techniques)•Strategies for sample purification, fractionation and trace enrichment•Hardware configurations and phase chemistries•Method development (tips & tricks)•Troubleshooting

❱ Practical part:•Conduct a SPE method development•Measurement of a realistic sample•Identify common error sources•Fundamentals of fast chromatography (settings in Empower)

PrerequisitesNone




Fundamentals of HPLC

Language: Danish, English, FrenchLocation: Denmark, France, Sweden

Ref.: 750000276 – 3 days

Course DescriptionDuring the course the different LC principles, techniques, and separation modes will be covered. The course structure with lectures in the morning, and lab exercises in the afternoon.

Topics Covered ❱ HPLC theory ❱ HPLC instruments ❱ Straight and reversed phase chromatography ❱ Ion exchange chromatography ❱ Size exclusion chromatography ❱ Gradient elution ❱ Method development ❱ Quantitation ❱ Sample preparation ❱ Troubleshooting and maintenance

Who Should AttendAll who want a basic understanding of HPLC.

PrerequisitesNone


106


Fundamentals of HPLC (Theory)

Language: Danish, Dutch, English, Finnish, GermanLocation: Belgium, Denmark, Finland, Germany, Norway, Sweden, The Netherlands, United Kingdom

Ref.: 750000463 – 2 days

Course Description During the course the different LC principles, techniques, and separation modes will be covered. T his course is designed to help individuals enhance and expand upon their fundamental knowledge and understanding of liquid chromatography (HPLC). Investigation of various liquid chromatographic principles, techniques, and separation modes will be discussed. Ultimately, an improved understanding of this technique will allow for informed decisions to be made in order to further enhance laboratory efficiency.

Course Topics ❱ HPLC theory ❱ HPLC instruments ❱ Normal and reversed phase chromatography ❱ Ion exchange chromatography ❱ Size exclusion chromatography ❱ Gradient elution ❱ Method development ❱ Quantitation ❱ Sample preparation ❱ Troubleshooting and maintenance

Who Should AttendThis course is designed for laboratory personnel who are responsible for operating HPLC systems and require an enhancement/refreshment of their current HPLC skills.

PrerequisitesNone




HPLC Method Development

Language: Danish, Dutch, English, FrenchLocation: Belgium, Denmark, France, The Netherlands, Sweden, United Kingdom

Ref.: 750000164 – 3 days

Course DescriptionThe course will allow the participants to develop HPLC methods in a systematic way. Participants will learn how to choose columns and mobile phases, as well as optimize separations. The focus is on reversed phase separations, but the principles can be applied to other separation modes. The course is structured with lectures in the morning, and lab exercises in the afternoon.

Topics Covered ❱ Reversed phase HPLC theory ❱ General guidelines for method development ❱ Column parameters and selectivity ❱ Systematic optimization of isocratic reversed-phase methods ❱ Optimization of gradient methods ❱ Method development software ❱ Laboratory exercises

Who Should AttendThis course is designed for people who want to expand their knowledge on HPLC method development.

PrerequisitesBasic HPLC knowledge.


108


HPLC Method Development (Theory)

Language: Danish, English, Finnish, GermanLocation: Denmark, Finland, Germany, Norway, Sweden, United Kingdom

Ref.: 750000461 – 2 days

Course Description The course will allow the participants to develop HPLC methods in a systematic way. Participants will learn how to choose columns and mobile phases, as well as optimize the separations. The focus is on reversed phase separations, but the principles can be applied to other separation modes.

Topics Covered ❱ General guidelines for method development ❱ Reversed-phase column parameters ❱ Systematic method development 1 ❱ Systematic method development 2 ❱ Optimising gradient separations ❱ Reversed-phase column selectivity ❱ Method optimisation software techniques

Who Should AttendThis course is designed for people who want to expand their knowledge of HPLC method development.





HPLC Troubleshooting Dysfunctioning Diagnosis


Ref.: 750000468 - 3 days

Course DescriptionThe course describes the main problems encountered when using an HPLC system. The causes are analysed and solutions are provided. Theoretical and practical aspects are discussed for either equipment’s and columns.

Topics Covered ❱ Malfunctioning related to hardware HPLC•Pumping systems•Injection systems•Detectors•Stations computer data•Tubing and fittings•Parameters causing variation of retention time, area and peak symmetry

❱ Malfunctioning related to the chromatographic conditions•Mobile phases•Temperature•Filtration

❱ Lab practice•Hardware implementation of HPLC phenomena•Test pressure•Calculation of dead volume•Influence of the time constants

❱ Malfunctioning related to HPLC columns•Precautions•Parameters of tests

Who should attendThe course is dedicated for users who have firsthand experience in HPLC.

PrerequisitesThe configuration of the HPLC system must be specified at registration.


110


Practical Method Development with Lab

Language: EnglishLocation: United Kingdom

Ref.: 750000650 – 3 days

Course DescriptionThis three-day course will allow the participants to develop HPLC or UPLC methods in a systematic way. Participants will learn how to choose columns and mobile phases, as well as optimize separations. Focus is on reversed phase separations, but the principles can be applied to other separation modes. The course is structured with lectures in the morning and laboratory exercises in the afternoon using HPLC and/or UPLC Systems.

Topics Covered ❱ Reversed phase HPLC theory ❱ General guidelines for method development ❱ Column parameters and selectivity ❱ Systematic optimization of isocratic reversed phase methods ❱ Optimization of gradient methods ❱ Method development software ❱ Laboratory exercises

Who Should AttendThis course is designed for people who want to expand their knowledge on HPLC or UPLC method development.


Course Notes Each attendee will receive a course manual to keep for future reference and a Certificate of Attendance.



Principles and Practices in HPLC


Ref.: 750000155 – 4 days

Course Description The course addresses the theoretical and practical aspects of HPLC separations. The theoretical aspects relate to principles HPLC, reversed-phase separations and the development of methods by isocratic and gradient. Practical aspects are treated in the laboratory: they illustrate the theory and allow the use of hardware and software.

Topics Covered ❱ General principles and HPLC ❱ Basic parameters ❱ The HPLC pump, injector, and detector ❱ Laboratory ❱ Mounting an HPLC ❱ Software configuration ❱ Test columns ❱ Chromatographic modes ❱ Characteristics of reversed phase columns ❱ Development of separations by isocratic ❱ Laboratory ❱ Developed by isocratic ❱ With data acquisition software ❱ Development of separation in gradient mode ❱ Selection and use of solvents ❱ Flasks ❱ Laboratory ❱ Developed in gradient mode ❱ Data processing with the software ❱ Exposed ❱ Diagnostics and precautions for use ❱ Laboratory ❱ Software and data processing parameters ❱ Calibration, quantification and validation aspects ❱ Any other business

Who Should AttendThe course is aimed at novice users in HPLC or having a first experience and wishing to acquire the necessary knowledge to use the HPLC system and software. Through practical workshops, it can apply the theory explained in presentations, and optimize HPLC separations.

PrerequisitesSpecify the configuration of your HPLC system when registering.


112


Troubleshooting Common HPLC Problems

Language: Danish, Dutch, English, Finnish, French, GermanLocation: Belgium, Denmark, Finland, Germany, Ireland, The Netherlands, Norway, Sweden, United Kingdom

Ref.: 750000168 – 1 day

Course Description This course covers many commonly encountered HPLC problems. It will assist the chromatographer in logically identifying problems during the operation of his HPLC instrument, as well as identifying and preventing potential problems, thus reducing future downtime. Chromatographic examples are shown to make problem identification more clear.

Topics Covered ❱ Problem prevention•Potential sources of Chromatographic problems•Troubleshooting strategy

❱ Performance monitoring•Monitoring pressure•Determining system band spreading•Column efficiency testing•Tubing and connections

❱ Troubleshooting common problems•Peak shape problems•Retention time problems•Column problems•Chemistry problems•Baseline problems•Instrumentation problems•Vial and sample problems

❱ Column protection

Who Should AttendThe course is intended both for those developing new HPLC methods, and those who use HPLC instrumentation on a daily basis.





Waters Service Plans

Ultimate Peace of Mindn Protect capital investments

n Get preferred service and support

n Minimize costly downtime

n Control repair and maintenance costs

n Receive discounts on training courses

The right choice to increase laboratory productivity maintain peak performance and lower cost of ownership.

Learn more at

www.waters.com/serviceplans

114

[ SUPERCRITICAL FLUID CHROMATROGRAPHY (SFC) ]

115

116

[ SUPERCRITICAL FLUID CHROMATOGRAPHY (SFC) ]

Introduction to Supercritical Fluid Chromatography (SFC)


Ref.: 750000553 – 1 day

Course Description This course is designed to provide an overview of supercritical fluid chromatography technology, from analytical to preparative scale. Attendees will learn the fundamentals and some common practices of this chromatographic technique.

Topics Covered ❱ Brief history of SFC ❱ Physical properties of supercritical fluid and their implications on chromatography ❱ Unique hardware in SFC ❱ Detection choices for SFC ❱ Method Development ❱ Preparative SFC

Who Should AttendPersonnel responsible for evaluating new technology and/or for operating SFC systems and developing SFC separations.

PrerequisitesAttendees should have intermediate level HPLC experience. Some exposure to general chemistry and organic chemistry is helpful.




Supercritical Fluid Chromatography Purification with FractionLynx


Ref.: 750000557 – 3 days

Course Description This course is designed to provide an opportunity for attendees an in-depth exploration of preparative SFC hardware and FractionLynx autopurification software. Classroom activities will be enriched by a lab session. Course is split equally between classroom and hands-on session.

Topics Covered ❱ Overview impetus for purification technologies ❱ Balancing speed, chromatographic efficiency and system throughput ❱ Leveraging physical properties of supercritical fluid in purification applications ❱ Unique hardware in SFC (including component troubleshooting tips) ❱ MassLynx Software overview with a focus on the FractionLynx application Manager•Fraction collection set-up•Fraction method/Fraction trigger overview

❱ Lab application to enrich classroom session

Who Should AttendPersonnel responsible operating preparative SFC systems and optimizing purification efforts.

PrerequisitesAttendees should have intermediate level HPLC or basic SFC experience. Some exposure to preparative chromatography is recommended but not required.


118


Supercritical Fluid Chromatography Purification with ChromScope


Ref.: 750000556 – 2 days

Course Description This course is designed to provide an opportunity for attendees an in-depth exploration of preparative SFC hardware and ChromScope™ Software. Classroom activities will be enriched by a lab session. Course is split equally between classroom and hands-on session.

Topics Covered ❱ Overview impetus for purification technologies ❱ Balancing speed, chromatographic efficiency, and system throughput ❱ Leveraging physical properties of supercritical fluid in purification applications ❱ Unique hardware in SFC (including component troubleshooting tips) ❱ ChromScope Software overview ❱ Lab application to enrich classroom session

Who Should AttendPersonnel responsible operating preparative SFC Systems, Investigator, Prep 80 SFC, Prep 200 SFC, Prep 350 SFC, and optimizing purification efforts.

PrerequisitesAttendees should have intermediate level HPLC or basic SFC experience. Some exposure to preparative chromatography is recommended but not required.




ACQUITY UPC2 for Lab Practitioners

Language: Danish, Dutch, English, French, German, Italian, Spanish, SwedishLocation: Belgium, Denmark, Finland, France, Germany, Italy, The Netherlands, Norway, Spain, Sweden, Switzerland, United Kingdom

Ref.: 750000623 – 2 days

Course Description This course explains how the ACQUITY UPC2 System combines new chemistry with advances in instrumentation to access increased speed, resolution and sensitivity in chromatographic analysis. Included in the course are exercises such as basic login for Empower and MassLynx, becoming familiar with the ACQUITY Console software, priming the instrument, running test and sample solutions, and method transfer.

Topics Covered ❱ Understanding the unique differences between SFC and UPC2 with an introduction and global overview ❱ A brief refresher of SFC and an in-depth look at UPC2 chemistry ❱ An overview of the ACQUITY UPC2 System’s hardware and configuration ❱ Using the ACQUITY Console software for:•Priming the Binary Solvent Manager and Sample Manager•Calibrating the Sample Manager•Setting default parameters

❱ Maintaining your ACQUITY UPC2 System for optimal performance and reliability: ❱ Method Transfer and optimization from SFC to UPC2

❱ General troubleshooting techniques, including tips and tricks ❱ Utilizing Connections INSIGHT with its Intelligent Device Management (IDM) technology

Who Should AttendThis course is for individuals who want to push the limits of conventional SFC and understand the chemistry, operating principles and user maintenance of the ACQUITY UPC2 System. UltraPerformance SFC presents the possibility to extend and expand the utility of this widely used separation science.

PrerequisitesAttendees should be familiar with the basic principles of SFC.


120


Maintaining ACQUITY UPC2

Language: Danish, Dutch, English, Finnish, French, German, Italian, Spanish, SwedishLocation: Belgium, Denmark, Finland, France, Germany, Italy, The Netherlands, Norway, Spain, Sweden, Switzerland, United Kingdom

Ref.: 750000624 – 1 day

Course Description This course explains how to operate and perform routine maintenance for optimal performance. Included in this course are exercises that will enable you to become familiar with routine and more advanced user maintenance procedures.

Topics Covered ❱ Maintaining your ACQUITY UPC2 System for optimal performance and reliability by replacing components

during a routine maintenance such as the pump head seals, plunger, and needle assembly ❱ Having information to change the detector lamp and clean the flow cell ❱ General troubleshooting techniques, including tips and tricks ❱ Utilizing Connections INSIGHT with its Intelligent Device Management (IDM) technology

Who Should AttendThis course is for individuals who are responsible for the day to day maintenance of their UltraPerformance Convergence Chromatography (UPC2) system.

PrerequisitesAttendees should be familiar with the basic principles of HPLC, and have followed the “ACQUITY UPC2 for Laboratory Practitioners” course.


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Waters Application Training and Support

Waters application specialists are available on-site or remotely to provide in-depth assistance with data interpretation and method development. T hey will familiarize your staff with instrument or software and provide guidance on application development.

Most popular application training offerings:n Pesticide Residue Analysis

n BioPharmaceutical – Intact Proteins, Oligos

n Clinical Applications – TDM and Pain Management

n Pharmaceutical – Structural Elucidation, Metabolite ID, QA/QC testing, Quantitation

n Proteomics


www.waters.com/applicationtraining

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[ ON-SITE EDUCATION ]

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Waters On-site training

Maximize learning at your location. Our existing training programs can be delivered “as is” or tailored to your specific laboratory challenges. By bringing a Waters Training Course to your site, not only will you select convenient dates to train your group, but you will also reduce or eliminate travel costs.

Benefits of on-site training:n Perfect choice for laboratories that need to train

groups of employees – from 5 to 500 or more.

n Get a maximum number of employees trained in new skills or technology in a minimal amount of time for one flat fee.

n Train your entire group of users in a familiar, confidential environment.

n Create synergy to the learning experience as lectures, hand-on sessions stay relevant to your laboratory needs.

n Eliminate your staff’s travel costs and minimize time away from the laboratory.

n Leverage serious Waters brainpower – our certified instructors are not only experts; they’re talented teachers delivering maximum skills in the allotted time.


www.waters.com/onsite

Start planning a course at your site today!

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[ eLearning ]

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PART NUMBER COURSE TITLE

Empower 3 Advanced Topics Administrative Tools for Productivity eLearning Track 750002023750000780 Module 1 Empower 3 SW – Admin Tools750000781 Module 2 Empower 3 SW – User Management750000782 Module 3 Empower 3 SW – Projects Management750000783 Module 4 Empower 3 SW – The Project Window750000784 Module 5 Empower 3 SW – Nodes and Chomatgraph Systems Empower 3 Fundamentals of the Pro Interface eLearning Track 750002022750000813 Module 1 Empower 3 – Introduction and Log in750000814 Module 2 Empower 3 – Creating an Instrument Method750000816 Module 3 Empower 3 – Creating a Method Set750000817 Module 4 Empower 3 – Creating a Sample Set Method750000818 Module 5 Empower 3 – Acquiring Data750000820 Module 6 Empower 3 – Theory of ApexTrack Integration Algorithm750000819 Module 7 Empower 3 – Theory of Traditional Integration Algorithm750000821 Module 8 Empower 3 – Creating a Traditional Processing Method750000822 Module 9 Empower 3 – Create an ApexTrack Process Meth750000823 Module 10 Empower 3 – Review Data w/a Processing Method750000824 Module 11 Empower 3 – Modifying a Processing Metho750000825 Module 12 Empower 3 – Altering Samples and Process Data750000826 Module 13 Empower 3 – Reviewing Results750000827 Module 14 Empower 3 – Using Reports750000828 Module 15 Empower 3 – Modifying an Individual Report750000829 Module 16 Empower 3 – Modifying a Summary Report Empower 3 Fundamentals of the QuickStart Interface eLearning Track 750002024750000795 Module 1 Overview/Login of Quickstart Interface750000796 Module 2 Instrument Methods and Data Acquisition750000797 Module 3 Developing a Processing Method750000798 Module 4 Alter Sample and Other Functions750000799 Module 5 Use and Modify Report Methods750000800 Module 6 Manage Projects, Systems, and Accounts750000801 Module 7 Find Information Empower 3 Empower 3 in a Regulated Lab eLearning Track 750002000750000671 Module 1 Empower 3 Access750000672 Module 2 Empower 3 – System Audit Trail750000673 Module 3 Empower 3 – Project Audit Trail750000674 Module 4 Empower 3 – Data Management750000675 Module 5 Empower 3 – Electronic Sign Off750000676 Module 6 Empower 3 – Data Security750000677 Module 7 Empower 3 – Backup and Restore

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Empower 3 Empower 3 Workflow eLearning Track 750002001750000665 Module 1 Empower 3 – Login750000666 Module 2 Empower 3 – Method Setup750000667 Module 3 Empower 3 – Sample Acquisition750000668 Module 4 Empower 3 – Data Review750000669 Module 5 Empower 3 – Edit Features750000670 Module 6 Empower 3 – Reports Empower 3 Transitionning from Empower 2FR5 to Empower 3 FR2 750002026750002026 Module 1 User Interface Module 2 Project Window Module 3 Run Samples Window Module 4 Alter Sample and Component Editor Window ChromaLynx ChromaLynx eLearning Track 750002018750000702 Module 1 ChromaLynx – Non-Targeted Analysis750000703 Module 2 ChromaLynx – Targeted Analysis750000704 Module 3 ChromaLynx – Libraries750000811 Module 4 Positive:Targetd Screen of Detected Compounds MarkerLynx MarkerLynx eLearning Track 750002017750000700 Module 1 MarkerLynx – Overview and Method Setup750000701 Module 2 MarkerLynx – Data Processing and Review MassLynx MassLynx eLearning Track 750002020750000709 Module 1 MassLynx Architecture750000710 Module 2 MassLynx Data Acquisition750000711 Module 3 MassLynx Data Process/Review Chromatogram750000712 Module 4 MassLynx Data Processing/Review – Spectrum750000713 Module 5 MassLynx Data Processing -Strip Function MetaboLynx Metabo eLearning Track 750002019750000705 Module 1 Drug Metabolism Overview750000706 Module 2 MetaboLynx – Method Setup750000707 Module 3 MetaboLynx – Data Processing and Review750000708 Module 4 MetaboLynx – Advanced Topics NeoLynx NeoLynx eLearning Track 750002021750000808 Module 1 NeoLynx™: Overview, Sample Prep and Instrument Setup750000809 Module 2 NeoLynx: Creating Process Method and Reports


[ eLearning ]


TargetLynx TargetLynx eLearning Track 750002016750000696 Module 1 TargetLynx – Overview750000697 Module 2 TargetLynx – Method Setup750000698 Module 3 TargetLynx – Data Processing and Review750000699 Module 4 TargetLynx – Advanced Topics750000811 Module 5 Positive: Targeted Screen of Detected Componds750000810 Module 6 Quanpedia: Database Management and Method Creation HW/Systems eLearning TracksComplex Mixture Analysis (UPLC-QTof MS) 750002008750000690 Module 1 Fundamentals of LC-MS750000691 Module 2 Fundamentals of MassLynx750000657 Module 3 Solvent Considerations750000658 Module 4 Binary vs. Quaternary Gradient Systems750000659 Module 5 LC Contamination Issues750000693 Module 6 Intellistart: QTof-Based MS Systems750000695 Module 7 Elemental Composition750000702 Module 8 ChromaLynx – Non-Targeted Analysis750000794 Module 9 MS(e) Viewer750000811 Module 10 Positive: Targeted Screen of Detected Compounds Complex Mixture Analysis (UPLC-Quadrupole MS) 750002007750000690 Module 1 Fundamentals of LC-MS750000691 Module 2 Fundamentals of MassLynx750000657 Module 3 Solvent Considerations750000658 Module 4 Binary vs. Quaternary Gradient Systems750000659 Module 5 LC Contamination Issues750000692 Module 6 Intellistart: Quadrupole-Based MS Systems750000702 Module 7 ChromaLynx – Non-Targeted Analysis750000811 Module 8 Positive: Targeted Screen of Detected Compounds General Liquid Chromatography (LC) 750002013750000657 Module 1 Solvent Considerations750000658 Module 2 Binary vs. Quaternary Gradient Systems750000659 Module 3 LC Contamination Issues750000788 Module 4 Troubleshooting Peak Shape750000787 Module 5 Sample Injection750000773 Module 6 Practical Tips for UV and PDA Detection

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[ eLearning ]


Intact Protein Analysis (UPLC Qtof MS) 750002009750000690 Module 1 Fundamentals of LC-MS750000691 Module 2 Fundamentals of MassLynx750000657 Module 3 Solvent Considerations750000659 Module 4 LC Contamination Issues750000714 Module 5 Intact Protein Instrument Setup and Data Acquisition750000715 Module 6 MaxEnt 1 and Transform750000716 Module 7 BioPharm Intact Protein Method Setup and Process750000717 Module 8 BioPharm Intact Protein – Data Analysis750000791 Module 9 nanoACQUITY Tips and Tricks LC-MS Principles and Concepts 750002012750000660 Module 1 LC-MS Introduction750000661 Module 2 Ionization Modes750000662 Module 3 Mass Analyzers750000663 Module 4 LC Method Development750000664 Module 5 Quantification Using MS750000772 Module 6 Atmospheric Solids Analysis Probe Metabolite Identification (UPLC-QTof MS) 750002005750000690 Module 1 Fundamentals of LC-MS750000691 Module 2 Fundamentals of MassLynx750000657 Module 3 Solvent Considerations750000658 Module 4 Binary vs. Quaternary Gradient Systems750000659 Module 5 LC Contamination Issues750000693 Module 6 Intellistart: QTof-Based MS Systems750000695 Module 7 Elemental Composition750000705 Module 8 Drug Metabolism Overview750000706 Module 9 MetaboLynx – Method Setup750000707 Module 10 MetaboLynx – Data Processing and Review750000708 Module 11 MetaboLynx – Advanced Topics Metabonomics/Metabolomics (UPLC-Qtof ms) 750002006750000690 Module 1 Fundamentals of LC-MS750000691 Module 2 Fundamentals of MassLynx750000657 Module 3 Solvent Considerations750000658 Module 4 Binary vs. Quaternary Gradient Systems750000659 Module 5 LC Contamination Issues750000693 Module 6 Intellistart: QTof-Based MS Systems750000695 Module 7 Elemental Composition750000700 Module 8 MarkerLynx – Overview and Method Setup750000701 Module 9 MarkerLynx – Data Processing and Review


[ eLearning ]


MS instrumentation 750002015750000692 Module 1 Intellistart: Quadrupole-Based MS Systems750000693 Module 2 Intellistart: QTof-Based MS Systems750000694 Module 3 QuanOptimize750000695 Module 4 Elemental Composition750000772 Module 5 Atmospheric Solids Analysis Probe750000793 Module 6 Ion Mobility Tuning and Data Acquisition on the Synapt G2-S Peptide Mapping (UPLC Qtof MS) 750002010750000690 Module 1 Fundamentals of LC-MS750000691 Module 2 Fundamentals of MassLynx750000657 Module 3 Solvent Considerations750000659 Module 4 LC Contamination Issues750000718 Module 5 Peptide Map – Instrument Setup and Data Acquisition750000719 Module 6 MaxEnt 3 and De Novo Sequencing750000720 Module 7 BioPharm. Peptide Mapping Method Setup and Process750000721 Module 8 BioPharm. Peptide Mapping Data Analysis750000791 Module 9 nanoACQUITY Tips and Tricks Quantitation (UPLC Quadrupole MS) 750002004750000690 Module 1 Fundamentals of LC-MS750000691 Module 2 Fundamentals of MassLynx750000657 Module 3 Solvent Considerations750000658 Module 4 Binary vs. Quaternary Gradient Systems750000659 Module 5 LC Contamination Issues750000692 Module 6 Intellistart:Quadrupole-Based MS Systems750000694 Module 7 QuanOptimize750000696 Module 8 TargetLynx – Overview750000697 Module 9 TargetLynx – Method Setup750000698 Module 10 TargetLynx – Data Processing and Review750000699 Module 11 TargetLynx – Advanced Topics

The Basics of HPLC 750002002750000678 Module 1 Theory of HPLC/TUV750000679 Module 2 Operation of HPLC/TUV750000680 Module 3 Maintenance of HPLC/TUV750000681 Module 4 Theory of HPLC/PDA750000682 Module 5 Operation of HPLC/PDA750000683 Module 6 Maintenance of HPLC/PDA750000773 Module 7 Practical Tips for UV and PDA Detection750000788 Module 8 Troubleshooting Peak Shape

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[ eLearning ]


The Basics of UPLC 750002003750000684 Module 1 Maintenance of UPLC/PDA750000685 Module 2 Theory of UPLC/TUV750000686 Module 3 Operation of UPLC/TUV750000687 Module 4 Maintenance of UPLC/TUV750000688 Module 5 Theory of UPLC/PDA750000689 Module 6 Operation of UPLC/PDA750000773 Module 7 Practical Tips for UV and PDA Detection750000791 Module 8 nanoACQUITY Tips and Tricks750000838 Module 9 Fundamentals of UPLC-Theory and Advantages750000844 Module 10 ACQUITY UPLC – Tips and Techniques Unifi Unifi eLearning Track 750002011750000722 Module 1 UNIFI Overview750000723 Module 2 UNIFI Administration750000724 Module 3 UNIFI Instrument Systems and Configuration750000725 Module 4 UNIFI Data Acquisition750000726 Module 5 UNIFI Data Review750000727 Module 6 UNIFI Reporting750000728 Module 7 UNIFI Signature Methods750000729 Module 8 UNIFI Scientific Library Acquity Qda Detector operator training 750002025 Alliance 2695 Op/Maint. eLearning Track 750000769 Miscellaneous 750000787 Sample Injection750000789 Quantitation by LC-MS750000790 Quadrupole Legacy Instruments750000812 MassLynx Security750000831 Atmosphere Pressure GC750000845 ACQUITY UPLC H-Class – Tips and Techniques


[ eLearning ]

Registration Form

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Promotional Code:

Payment Options:

Check Number:

Purchase Order Number:

Name:

Company Name:

Department:

Address:

City:

State, Zip, Country:

Phone:

Fax:

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[ NOTES ]

iRequestService Requests Made Easy iRequest Phone Support

Get technical phone support on Waters LC, MS and SFC Instruments and Software.(Serial # or Support ID required.)

iRequest On-site Service

Ask a Field Service engineer to be dispatched for Performance Maintenance, Repair Visit, Qualification, or Relocation.(Serial # or Support ID required.)

iRequest On-site Training

Request information on training based on your group size, schedule, and budget.(Login to Waters account required.)

n Immediate email confirmation

n Safe and secure

n Fast and easy

To learn more, go to www.waters.com/irequest

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[ COURSE CATALOG – EUROPE 2015-2016 ]

Waters, The Science of What’s Possible,ACQUITY, ACQUITY UltraPerformance LC, ACQUITY UPC2, ACQUITY UPLC, Alliance, Connections INSIGHT, Empower, HDI, HDMS, High Definition, MassLynx, Micromass, Millennium, NANOACQUITY, NuGenesis, QDa, UltraPerformance LC, UNIFI, UPC2, UPLC, Waters Quality Parts, and Xevo are trademarks of Waters Corporation. ApexTrack, AutoPurification, AutoPurify, Baseline, BiopharmaLynx, ChromaLynx, ChromScope , DriftScope , eCord, eLab Notebook Proteomics, FractionLynx, IntelliStart, iRequest, LAC/E, LockSpray, MALDI SYNAPT, MarkerLynx, MassFragment, MaxEnt, MetaboLynx, NanoFlow, NanoLockSpray, NeoLynx, OpenLynx, ProteinLynx Global SERVER , Q-Tof, QuanLynx, QuanOptimize, QUANPEDIA, SDMS Vision Publisher, SystemsQT, TargetLynx, UltraPerformance Convergence Chromatography, UltraPerformance SFC are trademarks of the Waters Corporation. All other trademarks are the property of their respective owners.

©2015 Waters Corporation. Printed in the France January 2015 720001070EN AW-CP-IH

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FOR REGISTRATION, LOCATION, FURTHER DETAILS, PLEASE VISIT OUR W EBISTE

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Phone 33 1 30 48 72 00Fax 33 1 30 48 72 01

Waters MS Technology Centre Waters GmbHMicromass Atlas Park, Simons Way Europaallee 27–29Manchester, M22 5PP, United Kingdom 50226 Frechen, Germany

Phone 44 161 435 4100 Phone 49 2234 9207 0Fax 44 161 435 4444 Fax 49 2234 9207 99

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SALES OFFICES - Waters Corporation · 2015-01-22 · [ COURSE CATALOG – EUROPE 2015-2016 ]...

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