To whom correspondence should be addressed.E mail

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Abstract

Key Wordsresponsive polymers,

sensor,bimolecular,

analytical application,molecularly imprinted polymer

PolymerizationQuarterly, 2014

Volume 4, Number 2Pages 59-71

ISSN: 2252-0449

Responsive Polymers for Analytical and Biosensing Applications

Laleh Adlnasab*, Azadeh Pirisedigh, Samira OsatiDepartment of Polymer and Petrochemicals, Standard Research Institute, P.O. Box:

31745-139, Karaj, Iran

Received: 9 September 2013, Accepted: 28 June 2014

These days responsive polymers are used in a wide range of applications. Around the

world researchers have made efforts on responsive polymers with high performance

which respond to a variety of stimuli. The stimuli-responsive polymers have the ability

to respond physically and chemically in response to environmental changes. Also, these

materials have enormous potential in a wide range of modern industries. The environmental

In this paper, we focus on the analytical and biosensing applications. While polymer-based

systems can be engineered to respond to a single stimulus, they can also be made to respond

to multiple stimuli. Many applications associated with health, energy and the environment.

With so much chemical versatility and a wide reaching array of applications, the future is

bright for stimuli-responsive polymers.

laleh_adlnasab@yahoo.com

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pH

laleh_adlnasab@yahoo.com

ISSN: 2252-0449

DNA

pH

PNIPAM

(lower critical solution

°C temperature, LCST)

PNIPAM

LCST

pH

PNIPAM

(pNIPAm-co-acrylic acid, AAC PNIPAM

AAC

PNIPAM

pH

pH

PNIPAM-co-AAC

pH> Pka AAc

N N N

poly(2-(2-methoxyethoxy

-ethyl methacrylate-b-oligo(ethylene glycol)methacrylate-b

poly(N-isopropylacrylamide)

(hydrodynamic diameter, DH) DH ± nm pNIPAm-co-AAc

acrylic acid))

pH

°C °C

pH

pH

pKa

pH

ATRP

PNIPAM

PNIPAM HPLC

PIPAAm-brush-grafted silica-bead column(IP-B PIPAAm

poly(tert-butylacrylamide (tBAAm)-b-IPAAm) brush-grafted silica-bead column (tBIP-B

pH

PDPA PDEA

pH PDPA pH PDEA

PDPA HCl PDPA

pH PAA

pH

pH

pH

pH

FeCl3 CaCl2

pH

DNA

PBA

PNIPAM PBA

PDEA PDPA pH

pH

pH APBA

APBA

AAC PNIPAM

PHA PHA

PHA-Biotion PHA

PHA-Biotion

AAC NIPAM pH

A

PNIPAM

DNA

PHA-BIOTIN

PNIPAm-co-Aac PHA-BIOTIN

FTIR

PDMS

IT0 PET

LTM

Fe3O4 Fe2O3

NIPAM

MRI

TNT

ng/mL mm

DNB

cmps

TNT

su-8

ppb

MIP

TNT

PS

CPS

PS

NIPAM RAFT

NIPAM

MIP

molecular imprinting

MIP

MIPC (molecu- mol

larly imprinted polymer capacitive

II MIP

II

MIP

A/μmol μ mol

III

CNTPE

SS-N26Gpul

LCST

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