Research Fund : Roche, Takeda, Kyowa-Kirin, J&J, Pfizer, Donga, Celltrion,Novartis,

- More common in far eastern Asia and some area of south America

- More common in male - Mostly presented stage I or II- Refractory to anthracycline based chemotherapy- Sensitive to radiation - Sensitive to L-asparaginase

M/63 Extranodal NK/T-cell lymphoma

• s/p CHOP #3 (2011.6.2-7.19) → PD

• s/p IMEP/L-aspa (2011.8.11-9.1) → PD : orbital involve

• s/p R-dmCODOX-MIAC#1 (2011.9.29) → PD

• s/p GEM-Dex: #1(2011.10.26) → PD

PD-L1 tumor cell/immune cell (-/-) PD-L1 tumor cell/immune cell (-/+)

PD-L1 tumor cell/immune cell (-/+) PD-L1 tumor cell/immune cell (+/+)

Cluster A

Cluster B

Cluster C