Reporting on Scientific Journal Articles (Jeremy Moore, M.A.)

8/7/2019 Reporting on Scientific Journal Articles (Jeremy Moore, M.A.)

http://slidepdf.com/reader/full/reporting-on-scientific-journal-articles-jeremy-moore-ma 1/58

Reporting on Scientific

Journal Articles

Jeremy Moore, M.A.

Senior Manager, Science Communications

American Association for Cancer Research

[email protected]



Why is Cancer Newsworthy?




Number 1 cause of death, surpassing heart disease in 2010





In the United States, it affects one in threewomen and one in two men





In the United States, it affects one in threewomen and one in two men

Consequences both biological and psychological




Money




Money

Government Money

NCI Budget, 2009: $4.96 billion





Money

Government Money



Budget Request for 2011

$5.26 Billion




Money

Private Money




Money

Private Money

Corporate and Philanthropic



Scientific Inquiry

In fact I have not failed 1,000 times.

I have successfully discovered 1,000

ways not to make a light bulb.--Thomas Edison



Scientific Inquiry

Cancer



Scientific Inquiry

Cancer

Out of control cell growth



Scientific Inquiry

Cancer

Out of control cell growth

More than 200 diseases



Cancer

CURE?



Cancer

CURE

vs.

CONTROL



Cancer: The Scientific Questions

Diagnosis



Diagnosis

Bladder Cancer

Pancreatic Cancer

Ovarian Cancer

Breast Cancer

Colon Cancer

Skin Cancer




Diagnosis

Screening



Screening

Questions surrounding PSA, Mammography,Colonoscopy



Sensitivity vs. Specificity

Sensitivity

Correctly Identifying WhoIs Sick

Specificity

Correctly Identifying WhoIs Not Sick



MicroRNA

The discovery of MicroRNA can be equated withthe idea that weve known for years that cars

existed and only recently discovered they have a

transmission. Its that fundamental.Philip Sharp, Ph.D., Nobel Laureate from M.I.T.



MicroRNA News from AnnualMeeting 2010

miR-21 and miR-106a are associated with anoverall poor prognosis and that overexpressionsof miR-181b and miR-203 are associated with

poor outcomes in blacks for colorectal cancer MicroRNA-31 (miR-31) repressed specific tumor

suppressors and, therefore, may be a novelpharmacologic target for lung cancer therapy

and chemoprevention.



MicroRNA News from AnnualMeeting 2010

High levels of miR-21 were significantlycorrelated with poor response to Herceptin.



DNA Methylation Levels




Diagnosis

Screening

Personalized Medicine



PersonalizedMedicine




Diagnosis

Screening

Personalized Medicine

Prevention



Prevention

At least half of all cancer deaths are preventableby what we already know about healthy eating,

exercise, maintaining appropriate weight,

avoiding smoking and going for regularscreenings.

Ernest T. Hawk, M.D., M.P.H.

Vice President of the Division of Cancer Preventionand Population Sciences at The University of

Texas M. D. Anderson Cancer Center.



Prevention

Healthy Living



Prevention

Healthy Living

Chemoprevention



Prevention



Scientific Inquiry

75 Clinical Trials

&

11 Systematic Reviews

Are Being Published Every Single Day

Bastian H, Glaszio P, Chalmers I, et al. (2010). Seventy-Five Trials and Eleven Systematic Reviews a Day: How Will WeEver Keep Up? P LOS Med 7 (9): e1000326. doi:10.1371/journal.pmed.1000326.



Journals to Watch

New England Journal of Medicine



Journals to Watch


Journal of the American Medical Association



Journals to Watch



Cancer



Journals to Watch



Cancer

Journal of Clinical Oncology



Journals to Watch

Cancer Research



Journals to Watch

Cancer Research

Clinical Cancer Research



Journals to Watch

Cancer Research


Cancer Epidemiology, Biomarkers & Prevention



Journals to Watch

Cancer Research



Cancer Prevention Research



Journals to Watch

Cancer Research



Cancer Prevention Research

Molecular Cancer Research

Molecular Cancer Therapeutics



NEWS FLASH

CANCER DISCOVERY



NEWS FLASH

CANCER DISCOVERY Officially announcing next week



NEWS FLASH


Editors in Chief, Jose Baselga, M.D, Ph.D. and Lewis

Cantley, Ph.D.



NEWS FLASH


Editors in Chief, Jose Baselga, M.D., Ph.D., and Lewis

Cantley, Ph.D.

Will be the premier venue for the publication andbroad dissemination of high impact research in allareas of cancer research



NEWS FLASH



Cantley, Ph.D.

Will be the premier venue for the publication andbroad dissemination of high-impact research in allareas of cancer research.

First papers will be published online April 2011



NEWS FLASH



Cantley, Ph.D.

Will be the premier venue for the publication andbroad dissemination of high-impact research in allareas of cancer research

First papers will be published online April 2011 In Print July 2011



THE ANATO MY OF AN ABSTRACT

Conclusions, not titles





Goals





Goals

Population Samples




Statistics

P Values, anything less than .05 is significant




Statistics

P Values, anything less than .05 is significant

Hazard Ratios

HR=1.23, 95% CI, 1.05-1.10



FOLLO W THE NEWS

Subscribe to Newswise

Check Eurekalert

Find a PR Person you trust



KEEP IN TOUCH

Jeremy Moore

Senior Manager, Science Communications

Office: 267-646-0557

Cell: 609-519-0212

[email protected]



THANK YOU

Reporting on Scientific Journal Articles (Jeremy Moore, M.A.)

Documents

Transcript of Reporting on Scientific Journal Articles (Jeremy Moore, M.A.)