Regulation of Secretion and Actions of Antidiuretic

Hormone

Process Diagrams Step-by-Step

Copyright © 2007 by John Wiley & Sons, Inc.

Osmoreceptors

High blood osmoticpressure stimulateshypothalamicosmoreceptors

1

Osmoreceptors

High blood osmoticpressure stimulateshypothalamicosmoreceptors

Osmoreceptorsactivate theneurosecretory cellsthat synthesize andrelease ADH

Hypothalamus

1

2

Osmoreceptors

High blood osmoticpressure stimulateshypothalamicosmoreceptors

Nerve impulsesliberate ADH fromaxon terminals inthe posteriorpituitary intothe bloodstream

Osmoreceptorsactivate theneurosecretory cellsthat synthesize andrelease ADH

Hypothalamus

ADH

1

2

3

Osmoreceptors

High blood osmoticpressure stimulateshypothalamicosmoreceptors

Nerve impulsesliberate ADH fromaxon terminals inthe posteriorpituitary intothe bloodstream

Osmoreceptorsactivate theneurosecretory cellsthat synthesize andrelease ADH

Hypothalamus

Sudoriferous(sweat) glandsdecrease waterloss by perspirationfrom the skin

Arterioles constrict,which increasesblood pressure

Kidneys retainmore water,which decreasesurine output

ADH

Target tissues

1

2

3

4

Osmoreceptors

High blood osmoticpressure stimulateshypothalamicosmoreceptors

Low blood osmoticpressure inhibitshypothalamicosmoreceptors

Nerve impulsesliberate ADH fromaxon terminals inthe posteriorpituitary intothe bloodstream

Osmoreceptorsactivate theneurosecretory cellsthat synthesize andrelease ADH

Hypothalamus

Sudoriferous(sweat) glandsdecrease waterloss by perspirationfrom the skin

Arterioles constrict,which increasesblood pressure

Kidneys retainmore water,which decreasesurine output

ADH

Target tissues

1

2

3

4

5

Osmoreceptors

High blood osmoticpressure stimulateshypothalamicosmoreceptors

Low blood osmoticpressure inhibitshypothalamicosmoreceptors

Nerve impulsesliberate ADH fromaxon terminals inthe posteriorpituitary intothe bloodstream

Osmoreceptorsactivate theneurosecretory cellsthat synthesize andrelease ADH

Hypothalamus

Inhibition of osmo-receptors reduces orstops ADH secretion

Sudoriferous(sweat) glandsdecrease waterloss by perspirationfrom the skin

Arterioles constrict,which increasesblood pressure

Kidneys retainmore water,which decreasesurine output

ADH

Target tissues

1

2

3

4

5

6