Progress Against Lung Cancer. 1970–1979 Progress Against Lung Cancer 1970–1979 Mid-1970s:...

Progress Against Lung

Cancer

Progress Against Lung Cancer

1970–1979


1970–1979Mid-1970s: Chemotherapy combinations prove effective in small cell lung cancer


1980–1989


1980–19891986: Second-hand smoke formally declared a carcinogen


1980–19891987: Scientists discover key genetic vulnerability in tumor cells – EGFR


1990–1999


1990–19991990–1992: Combining chemotherapy and radiation prolongs survival for non-small cell lung cancer


1990–19991993: Simultaneous radiation and chemotherapy boosts survival for small cell lung cancer


1990–1999Mid-1990s: New generation of chemotherapy drugs for non-small cell lung cancer


1990–19991995: Analysis affirms benefits of chemotherapy for advanced non-small cell lung cancer


1990–19991996: Topotecan approved as second round of treatment for small cell lung cancer


1990–19991999: Cranial radiation reduces risk of small cell lung cancer spreading to the brain

1999: Simultaneous chemotherapy and radiation proven most effective for stage III non-small cell lung cancer

1999: Giving radiation to the chest twice-daily increases survival for small cell lung cancer


2000–Present


2000–Present2000: Study links household radon exposure to lung cancer

2000: Second round of chemotherapy boosts survival in advanced non-small cell lung cancer


2000–Present2003: First targeted drug approved for non-small cell lung cancer


2000–Present2004: Studies show that specific EGFR mutations are associated with response to gefitinib

2004: FDA approves second targeted drug, erlotinib, for non-small cell lung cancer

2004–2005: Adjuvant therapy proven effective in lung cancer


2000–Present2005: Anti-angiogenic drug bevacizumab extends survival for advanced lung cancer

2005: New project to map lung cancer genome


2000–Present2008: Circulating tumor cells in the blood can help track treatment response in select patients


2000–Present2009: Maintenance therapy improves survival for advanced non-small cell lung cancer


2000–Present2010: Older patients should be considered for the same aggressive chemotherapy as younger patients

2010: Adding palliative care to standard chemotherapy improves survival for advanced lung cancer patients

2010: New lung cancer staging system is adopted

2010: Drug aimed at a newly identified target causes dramatic tumor shrinkages

2010: CT scanning reduces lung cancer deaths among heavy smokers


Five-Year Survival

11

12

13

14

15

16

17

18

19

1975

1977

1979

1981

1983

1985

1987

1989

1991

1993

1995

1997

1999

2001

2003

2005

2007

2009

Year of Diagnosis

% o

f Pa

tien

ts S

urv

ivin

g F

ive

Ye

ars

Source: National Cancer Institute


Mortality

32

37

42

47

52

57

62

1970

1972

1974

1976

1978

1980

1982

1984

1986

1988

1990

1992

1994

1996

1998

2000

2002

2004

2006

2008

2010

Year of Death

Ca

nce

r D

ea

ths

pe

r 1

00

,00

0 P

eo

ple



New Cases

46

51

56

61

66

71

1973

1975

1977

1979

1981

1983

1985

1987

1989

1991

1993

1995

1997

1999

2001

2003

2005

2007

2009

Year of Diagnosis

Ne

w C

an

cer

Ca

ses

pe

r 1

00

,00

0 P

eo

ple


Visit CancerProgress.Net for an interactive timeline of progress against a range of common cancers

CancerProgress.Net is a project of the American Society of Clinical Oncology, which represents nearly 30,000 physicians who treat people with cancer and

research new cures

Progress Against Lung Cancer. 1970–1979 Progress Against Lung Cancer 1970–1979 Mid-1970s:...

Documents

Transcript of Progress Against Lung Cancer. 1970–1979 Progress Against Lung Cancer 1970–1979 Mid-1970s:...