Structural Analysis of Histo-Blood Group Antigen Binding Specificity
Product Catalogue...immunodiagnostic assays for the global laboratory market. With extensive...
Transcript of Product Catalogue...immunodiagnostic assays for the global laboratory market. With extensive...
Specialist Immunologicals
Specialist Immunologicals
Product CatalogueProducts for IVD Manufacturers
Antibodies
Antigens
Clinical Specimens
Disease State Sera
Manufacturing Reagents
Quality Assurance
Our manufacturing site has quality systems approved to both ISO9001 and ISO13485:2003 certification. These, together with strict adherence to rigorous internal quality control procedures, ensure customers can be confident in the quality of Binding Site products.
Reducing our Impact on the Environment
Binding Site’s environmental policy outlines our commitment to limit the overall impact our processes have on the environment. The new 2011 head office was built with a focus on reduced energy and water consumption, has provisions for rainwater harvesting and meets strict carbon emission restrictions. All staff are trained on our Reduce, Reuse & Recycle policy.
Binding Site is a Specialist Protein company committed to the research, development, manufacture and distribution of innovative immunodiagnostic assays for the global laboratory market. With extensive expertise in antibody specificity technology, Binding Site gives clinicians and laboratory staff the tools to significantly improve diagnosis and management of patients across a range of cancers and immune system disorders.
Binding Site Offices
The headquarters of The Binding Site Group Ltd is located in Birmingham, UK and employs over 400 people.
In addition to research activities, the main site houses product development and manufacturing along with global distribution, marketing and administrative functions. Direct sales and product support to customers in the UK are based here together with sales and technical support provided to our distributor network in 81 countries .
Direct Binding Site sales and support organisations are also based in: San Diego, California for USA & Canada Schwetzingen, near Heidelberg for Germany, Austria & Switzerland Grenoble for France & French speaking distributor markets Barcelona for Spain & Portugal Prague for Czech Republic & Slovak Republic Antwerp for Belgium, Netherlands & Luxembourg Bergamo, near Milan for Italy São Paulo for Latin America
Binding Site
TABLE OF CONTENTS PAGE INTRODUCTION 1
ANTIBODIES 2 Human Immunoglobulins 2� Human Complement 3 � Human Acute Phase Proteins 3� Human Coagulation Proteins 4� Other Human Proteins 4� FITC Conjugated Human Immunoglobulin Antibodies 5� FITC Conjugated Human Complement/Coagulation Protein Antibodies 5� HRP Conjugated Human Immunoglobulins 6� HRP Conjugated Human Protein Antibodies 6� HRP Conjugated Monoclonal Antibodies 6� Animal Proteins 7 FITC Conjugated Antibodies to Animal Proteins 7 HRP Conjugated Antibodies to Animal Proteins 7 ANTIGENS 8 � Human Purifi ed Myeloma Antigens 8 � Other Human Native Antigens 8 Specialist Bulk Antigens 9
CLINICAL SPECIMENS (USA/Germany only) 10
DISEASE STATE SERA 11 � Human Myeloma 11� Human Thyroid Autoantibodies 11� Human Liver/Kidney Autoantibodies 11� Human Muscle Autoantibodies 11� Human Intestinal/Pancreatic Autoantibodies 12 Human Skin Autoantibodies 12� Human ENAs 12 � Human ANA/dsDNA Autoantibodies 12� Human ANCAs 12� Human Phospholipid Antibodies 13� Human Neurological Autoantibodies 13� Infectious Disease/Viral Positive Sera 13� Additional Disease State Sera 13
MANUFACTURING REAGENTS 14 � Bulk Volume Antibodies to Special Proteins 14 Human Rheumatoid Factor (RF)/IgG Absorbent 15
Introduction to Immunologicalsfrom Binding Site
As a manufacturer of a wide range of innovative in vitro diagnostic products, Binding Site understands the necessity for high quality raw materials and components. With a proven track record for over a quarter of a century, our expertise in immunisation and processing techniques has led to our international recognition as a key supplier of antibodies, antigens, bulk antisera, clinical specimens and diagnostic reagents.
Our fl exibility of scale from small R&D quantities to larger lots allow us to support your project whatever its size. Key elements for success lie within the way we work and the quality systems that are in place.
• Our commitment to continuous improvement allows us to enhance the quality of our product and service offering
• Working closely with researchers to ensure a focused and timely delivery of your product
• We are accredited to both ISO9001 and ISO13485:2003 and manufacture to GMP standards. Our internal quality systems ensure high standards, consistency, and reliability of product supply.
From initial product concept through to launch, we pledge to you excellence in quality, attention to detail, and the highest in customer service.
Whatever your requirements, we would welcome hearing from you and we look forward to working with you now and in the future.
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Binding Site offers a comprehensive range of antibodies focusing on human serum proteins including their subclasses. Affi nity purifi ed, IgG fraction and conjugations to Fluorescein-Isothiocyanate (FITC) and Horseradish Peroxidase (HRP) are routinely available. Additional custom formats can be made available on request.
Affi nity purifi ed antibodies (product codes starting A) are purifi ed against an immobilised antigen. In some instances, solid phase absorption is also utilised to reduce inter-species cross reactivity. IgG fraction antibodies (product codes starting P) are IgG fractions of sheep sera.
Human Immunoglobulins
A wide range of human immunoglobulins are available for use in immunoassay testing methodologies. In many instances the volumes of product are unspecifi ed to allow maximum customer choice and fl exibility.
Sheep Polyclonal Antibodies
Antibodies An
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PRODUCTDESCRIPTION FORMAT VOLUME CATALOGUE
NUMBERIgA IFE Grade Antisera Customer Specifi ed FX010
IgA Affi nity Purifi ed Customer Specifi ed AU010.X
IgA IgG Fraction 1mL PC010IgA IgG Fraction Customer Specifi ed PC010.XIgE IFE Grade Antisera Customer Specifi ed FX014IgE IgG Fraction Customer Specifi ed PC014.XIgG IFE Grade Antisera Customer Specifi ed FX004IgG Whole Serum Grade Customer Specifi ed PE004.XIgG Affi nity Purifi ed 2mg AU004IgG Affi nity Purifi ed Customer Specifi ed AU004.XIgG IgG Fraction 1mL PC004IgG IgG Fraction Customer Specifi ed PC004.XIgG (H & L) IgG Fraction 1mL PC003IgG (H & L) IgG Fraction Customer Specifi ed PC003.XIgG (H & L) Monkey Adsorbed Affi nity Purifi ed 1mL AU003.MIgG (Fd) IgG Fraction 1mL PC075IgG (Fd) IgG Fraction Customer Specifi ed PC075.XIgG1 Affi nity Purifi ed 0.5mg AU006IgG1 Affi nity Purifi ed Customer Specifi ed AU006.XIgG2 Affi nity Purifi ed 0.5mg AU007IgG2 Affi nity Purifi ed Customer Specifi ed AU007.XIgG3 Affi nity Purifi ed 0.5mg AU008IgG3 Affi nity Purifi ed Customer Specifi ed AU008.XIgG4 Affi nity Purifi ed 0.5mg AU009IgG4 Affi nity Purifi ed Customer Specifi ed AU009.X
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PRODUCTDESCRIPTION FORMAT VOLUME CATALOGUE
NUMBERHuman IgG4 MAb Clone HP6025 IgG Fraction Customer Specified MC011.X
Human IgG4 MAb Clone HP6025 IgG Fraction 0.2mg MC011
Monoclonal Antibodies
Human Complement - Sheep Polyclonal Antibodies
PRODUCTDESCRIPTION FORMAT VOLUME CATALOGUE
NUMBERC1q IgG Fraction 1mL PC020C1q IgG Fraction Customer Specified PC020.XC3c IgG Fraction Customer Specified PC023.XC3d IgG Fraction Customer Specified PC024.XC3d Whole Serum Grade Customer Specified PE024.XC4 IgG Fraction Customer Specified PC025.XC4 Binding Protein IgG Fraction 1mL PC026C4 Binding Protein IgG Fraction Customer Specified PC026.XC5 IgG Fraction Customer Specified PC027.XC8 IgG Fraction Customer Specified PC089.XFactor H [ß1H] IgG Fraction 1mL PC030Factor H [ß1H] IgG Fraction Customer Specified PC030.XFactor I [KAF/C3b Inactivator] IgG Fraction 1mL PC031Factor I [KAF/C3b Inactivator] IgG Fraction Customer Specified PC031.X
PRODUCTDESCRIPTION FORMAT VOLUME CATALOGUE
NUMBERIgM IFE Grade Antisera Customer Specified FX012IgM IgG Fraction Customer Specified PC012.XKappa Light Chain Affinity Purified 2mg AU015Kappa Light Chain Affinity Purified Customer Specified AU015.XKappa Light Chain IFE Grade Antisera Customer Specified FX015Lambda Light Chain Affinity Purified 2mg AU017Lambda Light Chain Affinity Purified Customer Specified AU017.XLambda Light Chain IFE Grade Antisera Customer Specified FX017
Sheep Polyclonal Antibodies - cont.
Human Acute Phase Proteins - Sheep Polyclonal Antibodies
PRODUCTDESCRIPTION FORMAT VOLUME CATALOGUE
NUMBERAntithrombin III IgG Fraction 1mL PC040Antithrombin III IgG Fraction Customer Specified PC040.Xß2 Microglobulin IgG Fraction Customer Specified PC043.XFibrinogen IgG Fraction Customer Specified PC056.XHaptoglobulin IgG Fraction 1mL PC058Haptoglobulin IgG Fraction Customer Specified PC058.X
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Human Coagulation Proteins - Sheep Polyclonal Antibodies
PRODUCTDESCRIPTION FORMAT VOLUME CATALOGUE
NUMBERAlpha Trypsin Inhibitor IgG Fraction Customer Specified PC060.XAntithrombin III IgG Fraction 1mL PC040Antithrombin III IgG Fraction Customer Specified PC040.XElastase IgG Fraction Customer Specified PC052.XFibrinogen IgG Fraction Customer Specified PC056.XFibrinogen Whole Serum Grade Customer Specified PE056.XFibronectin IgG Fraction Customer Specified PC057.XPlasminogen IgG Fraction Customer Specified PC065.XProthrombin IgG Fraction Customer Specified PC067.Xvon Willebrand Factor IgG Fraction 1mL PC054von Willebrand Factor IgG Fraction Customer Specified PC054.X
Other Human Proteins
PRODUCTDESCRIPTION FORMAT VOLUME CATALOGUE
NUMBERAlbumin IgG Fraction 1mL PC032Albumin IgG Fraction Customer Specified PC032.Xα2 HS Glycoprotein IgG Fraction Customer Specified PC124.XCarbonic Anhydrase 2 IgG Fraction Customer Specified PC076.XLD Isoenzyme V IgG Fraction 1mL PC154LD Isoenzyme V IgG Fraction Customer Specified PC154.XPrealbumin IgG Fraction Customer Specified PC066.XSuperoxide Dimutase (Cu/Zn) IgG Fraction 1mL PC077Superoxide Dimutase (Cu/Zn) IgG Fraction Customer Specified PC077.XTamm Horsfall Protein (Uromucoid) IgG Fraction 1mL PC071Tamm Horsfall Protein (Uromucoid) IgG Fraction Customer Specified PC071.X
Transferrin IgG Fraction 1mL PC070
Transferrin IgG Fraction Customer Specified PC070.X
Superoxide Dismutase (Mn) IgG Fraction Customer Specified PC096.X
Sheep Polyclonal Antibodies
PRODUCTDESCRIPTION FORMAT VOLUME CATALOGUE
NUMBERCD23 Clone BU38 IgG Fraction 0.2mg MC112CD23 Clone BU38 IgG Fraction Customer Specified MC112.X
Monoclonal Antibodies
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FITC Conjugated Human Immunoglobulin Antibodies
PRODUCTDESCRIPTION FORMAT VOLUME CATALOGUE
NUMBERIgA IgG Fraction Customer Specified PF010.XIgA [Monkey Adsorbed] Affinity Purified Customer Specified AF010.M.XIgG [Monkey Adsorbed] Affinity Purified Customer Specified AF004.M.XIgG1 Affinity Purified 0.5mg AF006IgG1 Affinity Purified Customer Specified AF006.XIgGAM (H+L) IgG Fraction Customer Specified PF002.XIgG IgG Fraction Customer Specified PF004.XIgG2 Affinity Purified 0.5mg AF007IgG2 Affinity Purified Customer Specified AF007.XIgG3 Affinity Purified 0.5mg AF008IgG3 Affinity Purified Customer Specified AF008.XIgG4 Affinity Purified 0.5mg AF009IgG4 Affinity Purified Customer Specified AF009.XIgM Affinity Purified Customer Specified AF012.X
IgM IgG Fraction Customer Specified PF012.X
IgG (H+L) Affinity Purified Customer Specified AF003.X
IgG (H+L) [Monkey Adsorbed] Affinity Purified Customer Specified AF003.M.X
Kappa Light Chain Affinity Purified 1mg AF015
Kappa Light Chain Affinity Purified Customer Specified AF015.X
Lambda Light Chain Affinity Purified 1mg AF017
Lambda Light Chain Affinity Purified Customer Specified AF017.X
PRODUCTDESCRIPTION FORMAT VOLUME CATALOGUE
NUMBERC1q IgG Fraction 1mL PF020C1q IgG Fraction Customer Specified PF020.XC3c IgG Fraction 1mL PF023C3c IgG Fraction Customer Specified PF023.XC4 IgG Fraction Customer Specified PF025.XVon Willebrand Factor IgG Fraction 1mL PF054Von Willebrand Factor IgG Fraction Customer Specified PF054.XFibrinogen IgG Fraction Customer Specified PF056.X
FITC Conjugated Human Complement/Coagulation Protein Antibodies
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PRODUCTDESCRIPTION FORMAT VOLUME CATALOGUE
NUMBERAlbumin IgG Fraction 1mL PP032Albumin IgG Fraction Customer Specified PP032.Xα1 a-Trypsin IgG Fraction 1mL PP034α1 a-Trypsin IgG Fraction Customer Specified PP034.XTransferrin IgG Fraction 1mL PP070Transferrin IgG Fraction Customer Specified PP070.X
PRODUCTDESCRIPTION FORMAT VOLUME CATALOGUE
NUMBERIgG4 clone HP6025 IgG Fraction 0.2mg MP011IgG4 clone HP6025 IgG Fraction Customer Specified MP011.X
HRP Conjugated Human Proteins - Sheep Polyclonal Antibodies
HRP Conjugated Human Immunoglobulins - Monoclonal Antibodies
HRP Conjugated Human Immunoglobulins - Sheep Polyclonal Antibodies
PRODUCTDESCRIPTION FORMAT VOLUME CATALOGUE
NUMBERIgG (H+L) [Monkey Adsorbed] Affinity Purified 1mg AP003.MIgG Affinity Purified 1mg AP004IgG Affinity Purified Customer Specified AP004.XIgG1 Affinity Purified 0.5mg AP006IgG1 Affinity Purified Customer Specified AP006.XIgG2 Affinity Purified 0.5mg AP007IgG2 Affinity Purified Customer Specified AP007.XIgG3 Affinity Purified 0.5mg AP008IgG3 Affinity Purified Customer Specified AP008.XIgG4 Affinity Purified 0.5mg AP009IgG4 Affinity Purified Customer Specified AP009.XIgA Affinity Purified 1mg AP010IgA Affinity Purified Customer Specified AP010.XIgM Affinity Purified 1mg AP012IgM Affinity Purified Customer Specified AP012.XKappa Light Chain Affinity Purified 1mg AP015Kappa Light Chain Affinity Purified Customer Specified AP015.XLambda Light Chain Affinity Purified 1mg AP017Lambda Light Chain Affinity Purified Affinity Purified AP017.X
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PRODUCTDESCRIPTION FORMAT VOLUME CATALOGUE
NUMBERSheep Anti-Dog IgG (H&L) IgG Fraction Customer Specifi ed PC230.XSheep Anti-Mouse IgG (H&L) Affi nity Purifi ed Customer Specifi ed AU271.XSheep Anti-Mouse α1 Hydroxylase IgG Fraction 1mL PC290Sheep Anti-Mouse α1 Hydroxylase IgG Fraction Customer Specifi ed PC290.XSheep Anti-Rabbit IgG (H&L) Affi nity Purifi ed Customer Specifi ed AU311.XDonkey Anti-Sheep/Goat IgG (H+L) Affi nity Purifi ed 2mg AU360
Donkey Anti-Sheep/Goat IgG (H+L) Affi nity Purifi ed Customer Specifi ed AU360.X
PRODUCTDESCRIPTION FORMAT VOLUME CATALOGUE
NUMBERDonkey Anti-Sheep/Goat IgG (H+L) IgG Fraction 1mg PF360
Donkey Anti-Sheep/Goat IgG (H+L) IgG Fraction Customer Specifi ed PF360.X
Sheep Anti-Cat IgG (H+L) IgG Fraction 1mL PF210Sheep Anti-Cat IgG (H+L) IgG Fraction Customer Specifi ed PF210.XSheep Anti-Dog IgG (H+L) IgG Fraction 1mL PF230Sheep Anti-Dog IgG (H+L) IgG Fraction Customer Specifi ed PF230.XSheep Anti-Rabbit IgG (H+L) Affi nity Purifi ed Customer Specifi ed AF311.X
PRODUCTDESCRIPTION FORMAT VOLUME CATALOGUE
NUMBERSheep Anti-Mouse IgG (H+L) Affi nity Purifi ed 1mg AP271Sheep Anti-Mouse IgG (H+L) Affi nity Purifi ed Customer Specifi ed AP271.XSheep Anti-Mouse IgG Affi nity Purifi ed 1mg AP272Sheep Anti-Mouse IgG Affi nity Purifi ed Customer Specifi ed AP272.XSheep Anti-Rabbit IgG (H+L) Affi nity Purifi ed 1mg AP311Sheep Anti-Rabbit IgG (H+L) Affi nity Purifi ed Customer Specifi ed AP311.X
Donkey Anti-Sheep/Goat IgG (H+L) Affi nity Purifi ed 1mg AP360
Donkey Anti-Sheep/Goat IgG (H+L) Affi nity Purifi ed Customer Specifi ed AP360.X
Antibodies to Animal Proteins
FITC Conjugated Antibodies to Animal Proteins
HRP Conjugated Antibodies to Animal Proteins
An
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Antigens
PRODUCTDESCRIPTION VOLUME CATALOGUE
NUMBER
Human IgG1 Kappa 1mL BP078
Human IgG1 Kappa Customer Specifi ed BP078.X
Human IgG1 Lambda Customer Specifi ed BP079.X
Human IgG2 Kappa 1ml BP080
Human IgG2 Kappa Customer Specifi ed BP080.X
Human IgG3 Kappa 1mL BP082
Human IgG3 Kappa Customer Specifi ed BP082.X
Human IgG3 Lambda Customer Specifi ed BP083.X
Human IgG4 Kappa 1mL BP084
Human IgG4 Kappa Customer Specifi ed BP084.X
Human IgG4 Lambda Customer Specifi ed BP085.X
Human IgA1 Kappa Customer Specifi ed BP086.X
PRODUCTDESCRIPTION VOLUME CATALOGUE
NUMBER
Human CRP 99% Pure (Ascitic fl uid) Customer Specifi ed BP300.X
Human CRP 80% Pure (Ascitic fl uid) Customer Specifi ed BP301.X
Human HBsAg type ay Customer Specifi ed BP302.X
Human HBsAg type ad Customer Specifi ed BP303.X
Human Prothrombin Antigen Customer Specifi ed BP314.X
Human Prothrombin Antigen - Glycerol Free Customer Specifi ed BP315.X
Human Sex Hormone Binding Globulin Customer Specifi ed BP316.X
Purifi ed Human Myeloma Antigens
Binding Site myeloma antigens are isolated from human serum and extensively purifi ed by ion exchange chromatography, gel fi ltration and affi nity chromatography. The isotype and light chain type of the myeloma protein is determined by immunoelectrophoresis. These products are supplied in buffer at greater than 95% purity.
Other Human Native Antigens
The purifi ed antigens listed below have been isolated from human material. They are supplied in buffer at variable concentrations.
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New antigens are being added continuously. Please visit www.immunologicals.com or check the new products list at the front of the catalogue.
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NEW Specialist Bulk Antigens
Exclusive to the United States and Canada, Binding Site are pleased to make available a comprehensive portfolio of infectious disease antigens from our ISO certifi ed partners Virion-Serion GmbH.
Material is provided with comprehensive QC test results for ELISA, SDS Page, Western Blot and Densometric Analysis; and is completely deactivated using Affi nity chromatography, UVC-irradiation, ß-propiolactone, and heat inactivation techniques.
PRODUCTDESCRIPTION
CATALOGUE NUMBER
Adenovirus Type 2 Hexon BA128VSAspergillus fumigatus BA132VSBordetella pertussis FHA BA120VS3Bordetella pertussis Toxin PT
BA120VS4
Bordetella pertussis whole-cell antigen
BA120VS8
Borrelia afzelii BA121VSBorrelia garinii BA121GVSBrucella abortus BA116VSCampylobacter jejuni BA139VSCandida albicans BA117VSChlamydia abortus EB+RB BA1373VSERChlamydia pneumoniae (Premium)
BA1371VS
Chlamydia pneumoniae EB+RB
BA1371VSER
Chlamydia trachomatis EB+RB
BA1372VSER
Chlamydia trachomatis MOMP
BA1372VSR2
Coxsackievirus Antigen recombinant
BA134VS01
Coxsackievirus B1 * BA134B1VSCoxsackievirus B5 * BA134B5VSCoxsackievirus B6 * BA134B6VSCytomegalovirus BA109VSEBV capsid Antigen P18 BA1361VSR22EBV capsid Antigen P23 BA1361VSR21Echinococcus granulosus BA107VSEcho Virus Type 6 * BA135VSEcho Virus Type 9 * BA135-9VSEchovirus Antigen recom-binant
BA135VS01
Enterovirus Antigen recom-binant
BA133VS01
Helicobacter pylori BA118VS
Herpes Simplex Virus 1 (HSV-1)
BA1051VS
Herpes Simplex Virus 2 (HSV-2)
BA1052VS
PRODUCTDESCRIPTION
CATALOGUE NUMBER
HSV-1 Glycoprotein G BA1051RVS-GInfl uenza A BA1231VSInfl uenza B BA1232VSLegionella pneumophila BA106VSLeptospira bifl exa BA125VSMeasles Virus BA102VSMeasles Virus (Premium) BA102VS-SMumps Virus BA103VSMycoplasma pneumoniae BA127VSMycoplasma pneumoniae P1
BA127VSP1
Parainfl uenza Virus Type 1 BA1261VSParainfl uenza Virus Type 2 BA1262VSParainfl uenza Virus Type 3 BA1263VSParvovirus NS1 BA122VSNS1Parvovirus Pep A (VP1 unique)
BA122VSVP1A
Parvovirus Pep B (VP2 C-term)
BA122VSVP1B
Parvovirus Pep C (VP1 N-term)
BA122VSVP1C
Parvovirus Pep D (VP1 C-term)
BA122VSVP1D
Parvovirus VP1 BA122VSVP1Parvovirus VP2 BA122VSVP1EParvovirus VP2 VLP BA122VSVP2Respiratory Syncytial Virus (RSV)
BA113VS
Rotavirus BA1193VSRubella Virus BA129G2VSRubella Virus Premium BA129VS-ETBE Virus BA112VSLTBE Virus (Premium) BA112VSToxoplasma gondii BA110VSVaricella Zoster Virus (VZV) BA104VSVaricella Zoster Virus (VZV) Glycoprotein
BA104VSG
Yersinia enterocolitica O:3 BA138VSYersinia enterocolitica O:8 BA13808VSYersinia enterocolitica O:9 BA13809VS
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Clinical Specimens USA / Germany only Clin
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Clinical specimens from human patients are essential, but often overlooked components.
Required for ensuring the validity and integrity of products prior to, and after market introduction, they are also necessary for a host of other critical studies:
• sample interference testing • assay specifi c performance characteristics • normal range determinations • validation studies • regulatory approval and clearance data and documentation
Specimens are available for a multitude of analytes, in a variety of different matrices (e.g. serum, plasma, urine, CSF), all of which can be collected and supplied to include any additional diagnostic information needed.
The integrity of specimens is always kept intact (frozen or refrigerated) and can be packaged to specifi c fi ll-volume requirements as a single source donor, or pooled sample. If necessary, required and requested documentation is completed according to jointly agreed SOPs and provided with each and every collection and shipment, along with our own CERTIFICATE OF TESTING for your records.
To discuss your specifi c requirements contact us on: [email protected] Groups Available
• Autoimmune • Cardiac • Diabetes • Hormones • Infectious Diseases • Metabolic • Special Proteins • Therapeutic Drugs
Please contact us if you do not see the group you require or checkwww.thespecimenbank.com
• Clinical Chemistries • Fertility • Diabetes • Haematology • Immunology • Thyroid • Tumour Markers
Dis
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Disease State Sera
Binding Site can provide you with a consistent and reliable source of Disease State Sera products for your needs. All of our offerings are suitable for the production of assay components, such as calibrators and controls. We maintain a large bank of material which cover a wide range of pathological conditions, autoimmune disorders and infectious diseases. Volumes are available in quantities from a milliliter (mL) to liters (L) and can be offered in a variety of formats i.e. serum, plasma or dialyzed serum from single donors.
1mL samples for evaluation are available on request to ensure compatibility with your requirements. Reservations against individual lots can be made while samples are being assessed.
Human Myeloma Disease State Sera
PRODUCTDESCRIPTION VOLUME CATALOGUE
NUMBER
IgG1 Kappa Customer Specifi ed BX020
IgG1 Lambda Customer Specifi ed BX021
IgA1 Kappa Customer Specifi ed BX028
IgA1 Lambda Customer Specifi ed BX029
IgM Kappa Customer Specifi ed BX030
IgM Lambda Customer Specifi ed BX031
PRODUCTDESCRIPTION VOLUME CATALOGUE
NUMBER
Anti-Thyroglobulin Customer Specifi ed BX114
Anti-Thyroid Peroxidase (TPO) Customer Specifi ed BX245
PRODUCTDESCRIPTION VOLUME CATALOGUE
NUMBER
Anti-Glomerular Base Membrane (GBM) Customer Specifi ed BX126
Anti-Mitochondrial Customer Specifi ed BX128
Anti Liver/Kidney Microsomal (LKM) Customer Specifi ed BX129
Human Thyroid Autoantibodies Disease State Sera
Human Liver/Kidney Autoantibodies Disease State Sera
PRODUCTDESCRIPTION VOLUME CATALOGUE
NUMBER
Anti-Striated Muscle Customer Specifi ed BX133
Anti-Smooth Muscle Customer Specifi ed BX134
Human Muscle Autoantibodies Disease State Sera
PRODUCTDESCRIPTION VOLUME CATALOGUE
NUMBER
Anti-Gastric Parietal Cell Customer Specified BX125
Anti-Pancreatic Islet Cell Customer Specified BX131
Anti-Gliadin IgG Customer Specified BX250
Anti-Tissue Transglutaminase (tTG) IgG Customer Specified BX253
Anti-Tissue Transglutaminase (tTG) IgA Customer Specified BX254
PRODUCTDESCRIPTION VOLUME CATALOGUE
NUMBER
Anti-ENA Sm Customer Specified BX100
Anti-ENA RNP Customer Specified BX101
Anti-ENA SSA (Ro) Customer Specified BX102
Anti-ENA SSB (La) Customer Specified BX103
Anti-ENA Jo1 Customer Specified BX104
Anti-ENA Scl-70 Customer Specified BX142
PRODUCTDESCRIPTION VOLUME CATALOGUE
NUMBER
Anti-ANA Homogeneous Customer Specified BX105
Anti-ANA Nucleolar Customer Specified BX106
Anti-Nuclear Coarse Speckled Customer Specified BX108
Anti-dsDNA (Native) Customer Specified BX109
Anti-ANA Fine Speckled Customer Specified BX144
Anti-ANA Speckled Customer Specified BX172
Human Intestinal/Pancreatic Autoantibodies Disease State Sera
Human ENAs (Extractable Nuclear Antigen Antibodies) Disease State Sera
Human ANAs (Anti-Nuclear Antibodies)/dsDNA (Anti-Double-Stranded DNS Antibodies)
Disease State Sera
PRODUCTDESCRIPTION VOLUME CATALOGUE
NUMBER
Anti-ANCA (Mixed) Customer Specified BX179
Anti-Myeloperoxidase (MPO) Customer Specified BX246
Anti-pANCA Customer Specified BX247
Anti-Proteinase III (PR3) Customer Specified BX248
Anti-cANCA Customer Specified BX249
Human ANCAs (Anti-Neutrophil Cytoplasmic Antibodies) Disease State Sera
PRODUCTDESCRIPTION VOLUME CATALOGUE
NUMBER
Anti-Pemphigus (Vulgaris) Customer Specified BX115
Anti-Paraneoplastic Pemphigus Customer Specified BX214
Human Skin Autoantibodies Disease State Sera
Disease S
tate Sera
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PRODUCTDESCRIPTION VOLUME CATALOGUE
NUMBER
Anti-Acetylcholine Receptor Customer Specifi ed BX122
Anti-Hu (ANNA-I) Customer Specifi ed BX199
Anti-Myelin Associated Glycoprotein Customer Specifi ed BX217
Anti-Yo (PCCA-1) Customer Specifi ed BX198
PRODUCTDESCRIPTION VOLUME CATALOGUE
NUMBER
Anti-Cardiolipin IgG Customer Specifi ed BX145
Anti-Cardiolipin IgA Customer Specifi ed BX227
Anti-Cardiolipin IgM Customer Specifi ed BX118
Anti-ß2GP1 IgG Customer Specifi ed BX255
Anti-ß2GP1 IgA Customer Specifi ed BX256
Anti-ß2GP1 IgM Customer Specifi ed BX257
Anti-Phosphatidylserine IgG Customer Specifi ed BX258
Human Neurological Autoantibodies Disease State Sera
Human Phospholipid Antibodies Disease State Sera
PRODUCTDESCRIPTION VOLUME CATALOGUE
NUMBER
Toxoplasma IgG Customer Specifi ed BX210
CMV IgM Customer Specifi ed BX212
EBV IgG Customer Specifi ed BX213
Rabies IgG Customer Specifi ed BX316
PRODUCTDESCRIPTION VOLUME CATALOGUE
NUMBER
Normal Human Plasma/Serum Customer Specifi ed BX050
Polyclonal Human IgG Customer Specifi ed BX055
RF Positive Customer Specifi ed BX110
CRP Positive Customer Specifi ed BX174
ß2 Microglobulin Positive Customer Specifi ed BX175
Positive Pregnancy Plasma Customer Specifi ed BX180
Anti-AB False Positive Customer Specifi ed BX221
Anti-C1Q CIC Customer Specifi ed BX272
Anti-CENP B Customer Specifi ed BX282
Anti-Actin Customer Specifi ed BX290
Non-Characterized Plasmaphoresis Fluid Customer Specifi ed BX291
Infectious Disease/Viral Positive Sera
Additional Disease State Sera
Manufacturing Reagents Man
ufactu
ring
Reag
ents
If you are a supplier of special protein tests, looking to expand your instrument menu offerings, need an improvement to an existing assay or require a reagent manufacturing partner; Binding Site can supply you with a complete solution.
We can provide IVD manufacturers with products offering the highest degrees of performance, purity, shelf life stability, and lot-to-lot consistency. Additionally, as our reagent manufacturing facility operates to both ISO9001, ISO13485:2003 and GMP quality systems, you can be reassured that your product will be made to the required specifi cations and documented accordingly.
We offer a range of material available as either bulk reagent or as components for use in assays. These can be provided as either standard antibodies, conjugated or latex bound.
NEW • Albumin • α-1-Acid Glycoprotein • α-1-Antitrypsin • Anti-Streptolysin O • ß-2-Microglobulin • Ceruloplasmin • CRP • Cystatin C • Haptoglobin • Immunoglobulin A • Immunoglobulin D • Immunoglobulin G • Immunoglobulin M • Prealbumin • Transferrin
These along with many of our other antibodies can be made available conjugated to a label that suits your technology and into reagents formatted to your needs.
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Human Rheumatoid Factor (RF)/IgG Absorbent
The accurate quantifi cation of human IgM in infectious disease assays may be disrupted by the presence of IgM class Rheumatoid Factor (RF) and by Immunoglobulin G (IgG). Human RF/IgG Absorbent is a reagent designed to remove both IgM class Rheumatoid Factor and IgG from serum prior to the quantifi cation of specifi c IgM.
PRODUCTDESCRIPTION
IgG REMOVAL CAPACITY FORMAT VOLUME CATALOGUE
NUMBERRF / IgG Absorbent 15 mg/mL Whole Serum 1 x 10mL (Non-US) IC050
RF / IgG Absorbent 15 mg/mL Whole Serum Customer Specifi ed IC050.X
visit us for more informationwww.immunologicals.com
June 2015MKG812E
www.immunologicals.com
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