Presentation hse13 k_10_04_2013_imslide
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Early leukemia diagnostics HSE 13K 10-04-2012 Andrey Senyut senyut@immunoslide.com
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Transcript of Presentation hse13 k_10_04_2013_imslide
Leukemia
Leading cause of death among children under 15
250 000 deaths per year
350 000 new cases per year
The disease is detected TOO LATE
Common methods of leukemia diagnostics are NOT SENSITIVE ENOUGH
ONLY 4% are diagnosed at the stage of preventive inspection
Problem
Immunoslide
Hi accuracy
Affordable price
Immunoslide Abnormal blood cells appear in a person’s blood stream when he has leukemia.
Pathological cells differ from normal ones by:
External appearance (morphology)
Antigens on their surface (immunophenotype)
There must be no cells with “CD11C-” antigen (special protein) on their surface when a person is healthy.
Common methods of leukemia diagnostics (blood smear) don’t deliver the data about cell’s surface antigens.
Immunoslide allows doctor to receive data both on the external appearance of blood cells and on the surface antigens of blood cells.
EXAMPLE
Pathological cells
EXAMPLE
Sensi(ve
Y Y Y Y
An$gen
Immobilized an$body
Blood cell
Immunoslide
gives 10 TIMES HIGHER CHANCE of finding leukemia at it’s early stage
Devise for early leukemia diagnos(cs.
Affordable
CD 4 CD 4 CD 8 CD 8
Immunoslide
Immunoslide (disposable)
Device for an automated analysis of immunoslide
+
Product
73% margin
200 000 rubles
15% margin
300 rubles per test
Overall market volume - 15.5 bln rubles
Russian market
PRIVATE MARKET GOVERNMENTAL MARKET
revenue in 5 years – 800 mln rubles
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20,000
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Thousands of rubles
half year
NPV = 41 mln rubles, r = 40% IRR = 69%
PBP = 3.8 years Required investments
54 mln rub
CF
CF without bringing in investmnets
EBITDA
Financial forecast Thousands of rubles
Thousands of rubles
half year
half year
Конкурентные методы ImmunoSlide
Flow cytometry
Immunocitochemistry
Blood smear
Morphological analysis ++ -‐-‐ -‐ +
Immunophenotyping + ++ + -‐-‐
Cost of one test 350 rubles
500 – 1000 rubles
600 – 1400 rubles
100 rubles
Cost of equipment 200 000 rubles
3 000 000 rubles
-‐ -‐
Dura(on of analysis 1,5 hour 0,5 hour 3 hours 0,5 hour
Simplicity of exploita(on + -‐-‐ -‐-‐ +
D. Rogachev’s children’s hematological center
Governmental clinical and diagnostic laboratories
Private clinical and diagnostic laboratories
Morozov children’s hospital
Partners
Hematological science center
– winner of the grant START 2012
We are Skolkovo residents
