By: Mauricio Alejandro Arango Restrepo

HOW STEM CELL IMPLANTS HELP HEAL TRAUMATIC BRAIN

INJURYAND

MASSIVE ENDOCYTOSIS IN CELLS

PEGAR PLEGABLE

How Stem Cell Implants Help Heal Traumatic Brain Injury

INTRODUCTION

How Stem Cell Implants Help Heal Traumatic Brain Injury

PART A

“For years, researchers seeking newtherapies for traumatic brain injury havebeen tantalized by the results of animalexperiments with stem cells. In numerousstudies, stem cell implantation hassubstantially improved brain function inexperimental animals with brain trauma. Butjust how these improvements occur hasremained a mystery.” ScienceDaily (Jan. 12,2012)

How Stem Cell Implants Help Heal Traumatic Brain Injury

PART B

It identified the mechanism bywhich neuronal cells aredamaged after a brain trauma,but also identified themechanism by which stemcells help repair neuralconnections

How Stem Cell Implants Help Heal Traumatic Brain Injury

PART C

Were identified around of400 proteins that responddifferently before theinjury and after stem celltransplantation promotingthe recovery of neuronalcommunication.

Calcineurin proteinwas identified asprotective againsttraumatic braininjury by accident

PART D

You can obtain more safe and effective therapies to restore brain

function

PERASONAL COMMENT

With advances in the use of stem cells fortissue repair opens in a new light to manypatients who have suffered traumatic braininjury type by different factors and can go fromfully assisted living to a more autonomous andself-conscious.

PART A

Massive Endocytosis in Cells

Massive endocytosis in a variety of cells experimentally manipulated by

manipulating the cell membrane.

PART B

Massive Endocytosis in Cells

Massive endocytosis does not use media of the

endocytic clathrin, use the fraction of the membrane

containing cholesterol

PART C

Massive Endocytosis in Cells

The likely mechanism of massive endocytosis is the

nanoscopic fusion in the line of membrane lipids that generate changes in it.

PART D

Massive Endocytosis in Cells

Massive endocytosis helps to identify membrane proteins

and that this fraction is associated

PERASONAL COMMENT

To identify the proteins found in the cellmembrane provides information about theiroperation and substances that are receivingthis knowledge in turn may provide newtherapeutic approaches targeted to cells withmore specific ligand thus avoiding theundesirable side effects for example withcancer chemotherapies often detrimental tothe quality of life of patients

MEDICAL UTILITY

PART A

Stem cell research opens new avenues fortherapy of patients with traumatic brain injury

PART B

MEDICAL UTILITY

Stem cell research aims to ensureterapeutucas more safe and effective fortraumatic brain injury

PART C

MEDICAL UTILITY

Massive endocytosis allow therecognition of membrane proteinswhich serve as points of departure formuch research in the field of molecularbiology

PART D

MEDICAL UTILITY

Massive endocytosis may provide new targets formore precise effect of drugs through therecognition of membrane proteins can reducedrug side effects

BIBLIOGRAPHY

Science Daily. How Stem Cell Implants Help Heal Traumatic Brain Injury,Study finds [internet].[S.C]: Science Daily: Jan. 12, 2012 [Access day: Jan 172012] Disposable in:http://www.sciencedaily.com/releases/2012/01/120112112639.htm

Science Daily. Massive Endocytocis in Cells, Study finds [internet]. [S.C]:Science Daily: Jan. 17, 2012 [Access day: Jan 17 2012] Disposable in:http://www.sciencedaily.com/releases/2012/01/110117143206.htm