Preliminary Programme 13th IMW 2011

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    13THIMW

    PARIS2011

    May 3-6, 2011

    Paris, Carrousel du Louvre

    Abstracts Submission: from June 2010 to January 2011

    Registration: Opening June 2010

    PRELIMINARYPROGRAM

    ME

    13h InnIn

    MYM WKShP

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    Welcome to Paris

    Dear Colleagues and Friends,It is both a privilege and an honour to invite you to attend the XIIIth International Myeloma Workshop to be held inParis from May 3 to 6, 2011.In continuation with the previous organizers of this important biannual event, we aim to provide a compelling

    scientic programme highlighting emerging advances in our understanding of the biology and treatment of mye-loma disease. We also aim to stimulate lively debate discussion within the myeloma community and to contributeto efcient diffusion of medical information.Striving to further improve the quality of the meeting through various initiatives is another exciting task for us. Thelocation of the Workshop, in the Carrousel du Louvre which is right in the city centre, will ensure that you all enjoyboth the meeting and the fascinating city of Paris.

    We are very much looking forward to welcoming you to Paris in May 2011!

    Jean-Paul Fermand Thierry Facon Philippe Moreau

    C F BSCS

    Submit a abstract based o your scietic work i oe of te followig categories:

    - Section A: Basic Biology- Section B: Boe Disease (icludig Imagig)- Section C: Cliical Studies (icludig rasplatatio)- Section D: Precliical Studies ad new Drugs- Section E: pidemiology, Progostic Factors, Quality of ife, Disease Complicatios ad reatmet oxicities- Section F: ter Plasma Cell Dyscrasias

    Abstracts will have to be submitted directly on the Internet.They will be mainly considered for poster presentation, only a few abstracts will be chosen for oral presentation.Accepted abstracts will be published in the Haematologica Journal (supplement).

    geda

    Submission opening: Jue 2010Submission deadline: Jauary 10, 2011Notication of acceptance: Marc 2011

    For further information on abstracts submission, please visit the website:

    www.myeloma-paris2011.com

    SUBMI n BSC BF JnUY 10, 2011!

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    PIMInY PGMM

    uesday May 3 Wedesday May 4 ursday May 5 Friday May 6

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    newly diagosed MM < 65 yrs:facts & questios

    Chair:D. Reece & V. Hungria

    How I treat?V. Rajkumar

    What are the current asked questions?Cooperative groups

    CelgeeSymposium

    The Continuum of Care for theMultiple Myeloma Patient

    Chair:K. Anderson &J.-L. Harousseau

    Molecular patways /

    geetics

    Chair:H. Avet-Loiseau & M. Chesi

    PnInG KCoffee break

    Visit of exhibition & posters area

    ucVisit of exhibition & posters area

    Coffee breakVisit of exhibition & posters area

    Coffee breakVisit of exhibition & posters area

    Coffee breakVisit of exhibition & posters area

    Coffee breakVisit of exhibition & posters area

    Coffee breakVisit of exhibition & posters area

    Boe disease: frompysiopatology to treatmet

    Chair:R. Bataille & B. Durie

    Waldestroms awardIntroduced byR. Kyle

    Welcome receptio at teMuse du ouvre

    Debate I:Post ig dose terapy, otig,

    cosolidatio or maiteace?

    Chair: J. Blad ;M. Attal & J.-P. Fermand

    new boe ad biologicalexploratio teciques iplasma cell disorders

    Chair:P. Greipp & R. Hjek

    Myeloma cast epropaty &

    amyloidosis

    Chair:G. Merlini & R. Comenzo

    prIM cologySymposium supported by

    novartis cology

    Strategies in Evolution:Bone Targeted Therapy for Myeloma

    Debate II:Sould we treat some patiets

    wit stage I MM?

    Chair:M. Gertz ;

    V. Mateos & S. Lonial

    Pleary abstract sessio I

    Chair:M. Cavo & G. Gahrton

    Invited speakers:H. Lokhorst &D. Joshua

    Moocloal immuoglobuli

    ad te erve, Waldes-troms macroglobuliemia

    Chair:S. Treon & M. Delforge

    Closig ceremoy

    Introducing IMW 2013:K. ShimizuPlasma cell Biology

    Chair:B. Klein & N. Munshi

    hig-risk etities of MM:

    from biology to treatmet

    Chair:K. Stewart & M. Kuehl

    new drugs ad terapeutic

    approaces

    Chair:J. San Miguel &M. Boccadoro

    newly diagosed MM > 65 yrs:facts & questios

    Chair:R. Alexanian & A. Palumbo

    How I treat?B. Barlogie

    What are the current asked questions?Cooperative groups

    Milleium akeda& Jasse-Cilag

    Symposium

    Proteasome inhibition in multiplemyeloma and its clinical implications

    Cosesus report

    Chair:N. Munshi

    Diagnosis criteria & criteria for

    treatment and retreatment

    Supportive care

    Pleary abstractsessio II

    Chair:P. Richardson & M. Attal

    ucVisit of exhibition & posters area

    ucVisit of exhibition & posters area

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    USDY MY 3, 2011

    I 10:00 - 10:30 OPENING TALK

    I 10:30 - 12:30 MOLECLAR PATHWAYS / GENETICSChair:H. Avet-Loiseau- FRA & M. Chesi- USA

    Mai lecture: Germinal center and post germinal center differentiation:the cradle of MM ..................................................................................................................................................................... R. Dalla-Favera- USA

    The different subtypes of MM ..................................................................................................................................................... R. Fonseca- USAThe genetic progression of MM....................................................................................................................................... H. Avet-Loiseau- FRAMai lecture: MicroRNAs in MM .................................................................................................................................................... C. Croce- USAPanel discussion

    I 12:30 - 14:00 LuNch

    Visit of exhibition & posters area

    I 14:00 - 16:00 PLASMA CELL BIOLOGYChair:B. Klein- FRA & N. Munshi- USA

    Introduction lecture: The PR system.............................................................................................................................. A.-H. Lee- USA

    Cytokine patways: which one to target? ...................................................................................................................................... B. Klein- FRA

    mTOR complex pathway in MM........................................................................................................................................

    A. Lichtenstein- USARole of syndecan-1 ............................................................................................................................................................... R.-D. Sanderson- USA

    Panel discussion

    I 16:00 - 16:30 cOffEE BrEAK

    Visit of exhibition & posters area

    I 16:30 - 18:30 BONE DISEASE: FROM PHYSIOPATHOLOGY TO TREATMENTChair:R. Bataille- FRA& B. Durie- USA

    Introduction lecture: .......................................................................................................................................................... G.-D. Roodman- USA............................................................................................................................................................................................................................ S. Yaccoby- USA............................................................................................................................................................................................................................... N. Giuliani- ITA

    ............................................................................................................................................................................................................................. B.-P. Ayati- USA

    ............................................................................................................................................................................................................................ P. Tassone- GBR

    ............................................................................................................................................................................................................... K. Vanderkerken- BEL

    Panel discussion

    I 18:30 - 19:15 WALDENSTROMS AWARDIntroduced byR. Kyle- USA

    I 20:30 - 23:00 WELCOME RECEPTION AT THE MSE D LORE

    PIMInY PGMM

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    WDnSDY MY 4, 2011

    I8:00 - 10:00NEWLY DIAGNOSED MM < 65 YRS: FACTS & ESTIONSChair:D. Reece- CAN& V. Hungria- BRA

    how I treat? ......................................................................................................................................................................................... V. Rajkumar- USA

    Wat are te curret asked questios?................................................................................................................... Cooperative groups

    EMN ........................................................................................................................................................................................ P. Sonneveld- NED

    CTN-BMT........................................................................................................................................................................................ S. Giralt- USA

    Pethema...................................................................................................................................................................................... L. Rosiol- ESP

    MRC ............................................................................................................................................................................................ G. Morgan- GBR

    IFM-DFCI ................................................................................................................................................................................... P. Moreau- FRA

    Arkansas ................................................................................................................................................................................. B. Barlogie- USA

    I 10:00 - 10:30 cOffEE BrEAK

    Visit of exhibition & posters area

    I10:30 - 12:30 CELGENE SYMPOSIMe Cotiuum of Care for te Multiple Myeloma PatietChair:K. Anderson- USA & J.-L. Harousseau- FRA

    Welcome ad itroductio:The changing dynamic of multiple myeloma treatment .............................................................................. J.-L. Harousseau- FRA

    Mechanisms of action and disease: intercellular eventsand immunomodulation ................................................................................................................................................................ S. Lentzsch- USA

    Mechanisms of action and disease: immune synapse ............................................................................................. M.-D. Davis- GBR

    Optimizing current therapeutic options for relapsed/refractorymultiple myeloma ............................................................................................................................................................... M.-A. Dimopoulos- GRE

    The evidence supporting continuous therapy in multiple myeloma ......................................................................... S. Giralt- USA

    From bench to bedside: combination regimens in the present and futuremanagement of multiple myeloma ................................................................................................................................ K.-C. Anderson- USA

    Close .................................................................................................................................................................................................. K.-C. Anderson- USA

    I 12:30 - 14:00 LuNch

    Visit of exhibition & posters area

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    I 14:00 - 16:00 HIGH-RIS ENTITIES OF MM: FROM BIOLOGY TO TREATMENTChair:K. Stewart- USA& M. Kuehl- USA

    t(4& 14) and genomic instability in high-risk MM ...................................................................................................... L. Bergsagel- USA

    The biochemical role of the histone methyltransferase MMSET in MM .................................................................... A. Licht- SUI

    Whole Genome Sequencing in high-risk MM ..................................................................................................................... K. Stewart- USAWhat is GEP-defined high-risk MM? ........................................................................................................................... J. Shaughnessy- USAThe implications of high-risk MM to therapy ........................................................................ G. Morgan- GBR& H. Einsele- GERPanel discussion

    I 16:00 - 16:30 cOffEE BrEAKVisit of exhibition & posters area

    I16:30 - 17:30 DEBATE I:POST HIGH DOSE THERAPY, NOTHING, CONSOLIDATION OR MAINTENANCEChair:J. Blad- ESP; M. Attal- FRA & J.-P. Fermand- FRA

    I 17:30 - 19:00 NEW BONE AND BIOLOGICAL EXPLORATION TECHNIESIN PLASMA CELL DISORDERSChair:P. Greipp- USA& R. Hjek- CZE

    Introduction lecture:Bone imaging in MM: old scaffolds and new avenues ............................................................................. M.-A. Dimopoulos- GRE

    Whole-body MRI in MM ........................................................................................................................................................ H. Goldschmidt- GER

    Pamidronate: Can the Dose be Lowered? ............................................................................................................................ P. Gimsing- DNE

    Zoledronic Acid in the Management of MM ........................................................................................................................ J.-A. Child- GBR

    Osteonecrosis of the Jaw ........................................................................................................................................................................ N. Raje- USA

    Should we use bone markers? ....................................................................................................................................................... E. Terpos- GREPanel discussion

    I 19:00 - 20:30 MYELOMA CAST NEPHROPATHY & AL AMYLOIDOSISChair:G. Merlini- ITA& R. Comenzo- USA

    Introduction lecture: New therapeutic approaches in AL ............................................................................. M.-B. Pepys- GBR

    Management of AL amyloidosis in 2011 ................................................................................................................................... G. Merlini- ITA

    Myeloma cast nephropathy ...................................................... N. Leung- USA& F. Bridoux- FRA &C.-A. Hutchinson- GBR

    I20:30 - 21:30 PRIME ONCOLOGY SYMPOSIM SPPORTED BY NOARTIS ONCOLOGYStrategies in Evolution: Bone Targeted therapy for Myeloma

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    hUSDY MY 5, 2011

    I8:00 - 10:00 NEWLY DIAGNOSED MM > 65 YRS: FACTS & ESTIONSChair:R. Alexanian- USA& A. Palumbo- ITA

    how I treat? ........................................................................................................................................................................................... B. Barlogie- USA

    Wat are te curret asked questios? .................................................................................................................. Cooperative groups

    GIMEMA ................................................................................................................................................................................... A. Palumbo- ITA

    Pethema .................................................................................................................................................................................. M. Mateos- ESP

    GMMSG ....................................................................................................................................................................................... C. Straka- GER

    Hovon/Nordic .......................................................................................................................................................................... A. Waage- NOR

    IFM ................................................................................................................................................................................................... T. Facon- FRA

    MRC ............................................................................................................................................................................................... F. Davies- GBR

    I 10:00 - 10:30 cOffEE BrEAK

    Visit of exhibition & posters area

    I10:30 - 12:30 MILLENNIM TAEDA & JANSSEN-CILAG SYMPOSIMBiological rationale for proteasome inhibition in multiple myelomaand its clinical implicationsChair & speakers to be announced

    Biological basis of proteasome inhibition in MMImpact of proteasome inhibition in the treatment of MM

    pdate on clinical studies on proteasome inhibition in MM

    Clinical management of peripheral neuropathy in MM

    I 12:30 - 14:00 LuNch

    Visit of exhibition & posters area

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    I 14:00 - 16:00 NEW DRGS AND THERAPETIC APPROACHESChair:M. Boccadoro- ITA & J. San Miguel- ESP

    Introduction lecture................................................................................................................................................................... K. Anderson- USA

    Preclinical basis for 2nd generation proteasome inhibitors ..................................................................................... D. Chauhan- USA

    Carfilzomib and other proteasome inhibitors: Clinical data ..................................................................... A.-J. Jakubowiak- USA

    New Imids ........................................................................................................................................................................................................ M. Lacy- USA

    Hypomethylating agents in MM ...................................................................................................... J. San Miguel- ESP& E. Ocio- ESP

    Monoclonal antibodies in the treatment of MM ......................................................................................................... S. Jagannath- USA

    Panel discussion

    I 16:00 - 16:30 cOffEE BrEAK

    Visit of exhibition & posters area

    I16:30 - 17:30 DEBATE II:SHOLD WE TREAT SOME PATIENTS WITH STAGE I MM?Chair:M. Gertz- USA;V. Mateos- ESP&S. Lonial- USA

    I17:30 - 19:00 PLENARY ABSTRACT SESSION IChair:M. Cavo- ITA & G. Gahrton- SWE

    Invited speakers: H. Lokhorst- NDE& D. Joshua- AUS

    I 19:00 - 20:30 MONOCLONAL IMMNOGLOBLIN AND THE NERE, WALDENSTROMSMACROGLOBLINEMIAChair:S. Treon- USA& M. Delforge- BEL

    Neuropathy in monoclonal gammopathy ................................................................................................................... E. Nobile-Orazio- ITA

    Poems syndrome .......................................................................................................................................................................... A. Dispenzieri- USA

    pdate in the treatment of WM ............................................................................................................. S.Treon- USA& V. Leblond- FRA

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    FIDY MY 6, 2011

    I8:00 - 10:00 CONSENSS REPORTChair:N. Munshi- USA

    Diagnosis criteria & criteria for treatment and retreatmentSupportive care including vaccination and infection prophylaxis (E. Anaissie- USA), management of anemia(H. Ludwig- AUT), vein thrombosis (A. Palumbo- ITA,), and bone disease (G.-D. Roodman- USA)

    I 10:00 - 10:30 cOffEE BrEAK

    Visit of exhibition & posters area

    I10:30 - 12:30 PLENARY ABSTRACT SESSION IIChair:P. Richardson- USA& M. Attal- FRA

    Invited speaker:A. Spencer- AUS

    I 12:30 - 15:00 CLOSING CEREMONYIntroducing IMW 2013 ...................................................................................................................................................................... K. Shimizu- JPN

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    Venue: Carrousel du Louvre99 rue de Rivoli

    75001 Paris - FRANCE

    Dates: May 3-6, 2011

    Ofcial Web site: www.myeloma-paris2011.com

    Registration: Before March 31, 2011:Reduced fees for early registration: 700 eurosReduced fees for early registration for IMS Member: 550 euros

    From April 1st, 2011:Regular fees: 800 euros

    Reduced fees for IMS Member: 650 euros

    Ofcial language: English

    Social event - Welcome Reception: Muse du LouvreMay 3, 2011

    Professional Congress Organizer - Europa Organisation

    Project Manager: Michal Sertain [email protected]

    Partnership Sales Representative: Afaf [email protected]

    Registration [email protected]

    Hotel reservation Carlson Wagonlit [email protected]

    INFORMATION

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    INFORMATION

    Committees - rgaizig CommitteeJean-Paul FERMAND - Thierry FACON - Philippe MOREA

    Under the auspices of the International Myeloma Society and its Board of Directors

    Robert A. YLE (President) ania HNGRIA

    enneth C. ANDERSON (ice-President) Nikhil MNSHIDouglas E. JOSHA (Secretary) Antonio PALMBOMorie Abraham GERTZ (Treasurer) Jess F. SAN MIGEL

    Brian G.M. DRIE azuyuki SHIMIZJean-Luc HAROSSEA Pieter SONNEELD

    French Scientic Advisory Committee

    Martine AMIOT Jean-Luc HAROSSEABertrand ARNLF Cyrille HLIN

    Michel ATTAL Bernard LEIN

    Herv AET LOISEA Catherine PELLAT-DECENYNCRgis BATAILLE Claire MATHIOT

    International Scientic Advisory Committee

    Raymond ALEXANIANBart BARLOGIE

    Peter Leif BERGSAGELJoan BLAD

    Mario BOCCADOROMichele CAOFaith DAIES

    Meletios A. DIMOPOLOSHermann EINSELE

    Rafael FONSECAGsta GAHRTON

    Sergio GIRALTNicola GILIANI

    Sundar JAGANNATH

    Henk M. LOHORSTHeinz LDWIGMaria-ictoria MATEOSGiampaolo MERLINIGareth J. MORGANS. incent RAJMARDonna E. REECEPaul G. RICHARDSONJohn D. SHAGHNESSYAndrew SPENCEReith STEWARTSteven TREONarin ANDERERENAnders WAAGE

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