1. By Maria AounMaria AOUN 5/22/2012

2. Leukemia is the cancer of the white blood cells. Maria AOUN 5/22/2012 3. White blood cells help your body fightinfection. Your blood cells form inyour bone marrow. In leukemia however, the bonemarrow produces abnormal whiteblood cells. Maria AOUN 5/22/2012 4. Maria AOUN 5/22/2012 5. Morphology of blood cells in leukemiaMaria AOUN 5/22/2012 6. Four types of leukemia: -Acute lymphocytic leukemia -Acute myeloid leukemia -Chronic lymphocytic leukemia -Chronic myeloid leukemia Maria AOUN 5/22/2012 7. Maria AOUN 5/22/2012 8. Common symptoms: Other symptoms:.Fever or chills .petechia (tiny red spots.weakness and fatigueunder the skin).frequent infections .swollen or bleeding.weight-loss gums.swollen or tender lymph .sweating (especially at nodes night).easy bleeding or bruising .bone or joint pain Maria AOUN 5/22/2012 9. Chemotherapy Other drug therapy and radiation Bone marrow and blood stem celltransplantation Maria AOUN 5/22/2012 10. .Chemotherapy.radiation therapy.stem cell transplants.infusion of donated white blood cells followingstem cell transplants.immune therapy.surgery to remove the spleen. Maria AOUN 5/22/2012 11. Clonal expansion and accumulation of greaterthan 20% leukemic myeloid blasts in the bloodor bone marrow . Maria AOUN 5/22/2012 12. Malignancy of children and adultscharacterized by the monoclonalproliferation and accumulation of immaturelymphoid cells in the bone marrow, blood,lymph nodes, and other organs includingspleen, liver, and CNS.Maria AOUN 5/22/2012 13. A clonal myeloproliferative disorder resulting in theoverproduction and over-proliferation of Philadelphiachromosome-positive myeloid cells.Maria AOUN 5/22/2012 14. Maria AOUN 5/22/2012 15. For more information, click here.Maria AOUN 5/22/2012 16. Maria AOUN 5/22/2012 17. BibliographyJournal ArticlesFlis K, Irvine D, Copland M, Bhatia R, Skorski T. Chronic myeloidleukemia stem cells display alterations in the expression of genesinvolved in oxidative phosphorylation. Leuk Lymphoma. 2012 May 23.[Epub ahead of print] PubMed PMID: 22616753.Other (Non-standard citation). The patient education institute. x-plain leukemia. 2010 April 02.Medline plus..National Institutes of Health. Childhood Leukemia. 2010.Medline plus..Current Medicine LLC. acute lymphoblastic leukemia blasts. 2005.Images MD..Diseasedex. Acute myeloid leukemia. 2000. Micromedex.Maria AOUN 5/22/2012 18. BonusMaria AOUN 5/22/2012