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    PHYSICAL MEDICINE &REHABILITATION

    APPROACHES TO PAINMANAGEMENT

    Steven D. Feinberg, M.D.

    Clinical Associate ProfessorStanford University School of Medicine

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    Introduction

    Many PMR approaches

    Traditionally minimally invasive

    Useful alone & in combination with otherapproaches

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    Acute Injuries - RICE

    RICE - is commonly invoked as the

    appropriate immediate response to injury

    Rest Ice

    Compression

    Elevation

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    Chronic Pain

    For chronic pain states, the physical

    modalities are more often used as adjuncts to

    pain treatment approaches

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    PMRApproaches Categorization

    Thermal

    Electrotherapy

    Physical modalities Manual therapies

    Therapeutic exercises

    Aerobic conditioning Functional restoration approaches

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    Thermal Therapies

    A number of thermal modalities that producepain relief directly and indirectly

    These include various cold applications

    and heat in the forms of radiant heat, ultrasound,shortwave diathermy, microwave and laser

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    Thermal Therapies

    All of these modalities may work indirectlyand through a counterirritant effect or directlythrough effects on peripheral nerves and free

    nerve endings Cold therapy tends to be used acutely to

    reduce swelling and pain of acute injury andinflammation

    Whereas heat is utilized after the acute injuryphase has subsided and for more chronicconditions

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    Thermal Direct & Indirect Effects

    More focused on the direct effects, but theindirect effects can be quite therapeutic

    Heat and cold application to the skin of the

    abdominal wall have a profound effect onpain resulting from spasm of the smoothmuscle in the GI tract or uterus There is a reduction in peristalsis and stomach

    acid production with heat and an increase with

    cold application Menstrual cramps are relieved with lower

    abdominal heat application

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    Heat

    Physiologic effects that produce pain relief direct results of the temp elevation on the tissue

    and cellular functions

    and through a reflex reaction Heat reduces pain & muscle spasm while

    decreasing joint stiffness and contractures

    Produces hyperemia, speeds metabolicprocesses & hematoma resolution

    Heat is useful for bursitis and tenosynovitisalong with superficial thrombophlebitis

    Causes an induction of reflex vasodilatation

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    Physiological Reactions to Heat

    The major factors determining the number

    and intensity of the physiological reactions to

    heat are:

    Level of tissue temperature: therapeutic range is

    narrow: 43o C [109.4o F] to 45o C [113o F]

    Duration of tissue temperature elevation [5 to 30

    minutes]

    Rate of temperature rise in tissues

    Size of the area treated

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    Superficial Heat

    While the physical properties differ, none of

    these agents are able to overcome the

    combination of skin tolerance, tissue thermal

    conductivity, and the body's response to

    produce localized temperature elevations of

    more than a few degrees at depths of a few

    centimeters Conduction, Conversion & Convection

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    Conduction Hot Packs

    Hot (hydrocollator) packs

    Clinically useful temperature for 30 minutes

    Advantages include low cost, minimal

    maintenance, long life, patient acceptance, and

    ease of use

    Alternatives include electric heating pads, gel

    pads, hot water bottles, and circulating water

    heating pads

    Exposure time: 20 minutes

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    Conduction Paraffin Baths

    Paraffin baths Mineral oil and paraffin (1:7)

    Temperatures of 52o C to 54o C are well tolerated

    because the mixture has a low heat capacity andan insulating layer of wax builds up on the treatedarea

    Dip method versus continuous immersion

    Contraindications: open wounds, skin infections,inadequate circulation, sensory loss

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    Conversion Heat Lamps

    Heat Lamps

    Inexpensive

    Versatile

    An easy way to warm superficial tissues

    250-watt bulb, 40 to 50 cm from the patient

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    Convection - Hydrotherapy

    Hydrotherapy

    Whirlpool baths & Hubbard tanks

    Pumps agitate water and provide convective

    heating, massage, and gentle debridement

    Temps: 33o C to 36o C are considered neutral

    Hubbard tank temps limited to 39o C

    Single extremity treatments can be more rigorousand in a healthy individual temperatures from 43o

    C to 46o C are possible

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    Convection - Hydrotherapy

    Used for burn and wound treatment at neutral

    temperatures

    Hydrotherapy can be effective for mobilization of

    joints, as an adjunct in the treatment ofrheumatoid arthritis, and for muscle spasm

    Hydrotherapy allows exercise of painful joints with

    reduced stress because water buoyancy reduces

    the gravitational forces Caution should be exercised with full submersion

    as body temperature may rise

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    Convection Contrast Baths

    Alternating immersion in hot and cold waterto produce a vascular exercise through activevasodilatation and vasoconstriction of the

    blood vessels Hot/cold ratios are used depending on patient

    tolerance; typically ratio is 4:1

    Thought to be effective due to reflex

    hyperemia produced by the alternatingexposure to heat (43o C) and cold (16o C)

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    DeepHeat Modalities

    Ultrasound

    Short wave Diathermy

    Microwave Laser (non-surgical)

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    Ultrasound

    Arbitrarily defined as sound at frequenciesabove the limits of human hearing (i.e., morethan 20,000 Hz)

    Ultrasound machines use ceramic and quartzpiezoelectric crystals to produce ultrasonicenergy

    Intensities of 0.5-2.0 Watts/cm2 are used

    Frequencies of 1 MHz (deep) or 3 MHz(superficial)

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    Ultrasound

    Pulsed versus Continuous

    Treatment time 5-10 minutes

    Deep-seated joints and fibrous scars with soft

    tissue are selectively heated by ultrasound asare myofascial interfaces, tendon and tendonsheath & nerve trunks

    Useful for painful amputation neuromas

    Phonophoresis includes the addition of asteroid which is forced into the tissue topotentiate treatment effectiveness

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    Ultrasound

    Precautions and contraindications include: fluid-filled cavities

    joint replacements containing cement/plastics

    open epiphyseal plates Cancer

    the eyes, brain & testicles should be avoided

    should not be used over a pregnant uterus

    Pain is used as an endpoint to avoid tissuedestruction

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    Short Wave Diathermy

    Radio waves are used to heat superficialtissue by conversion with induction coilapplicators or condenser pads

    Most commonly used frequency: 27.12 MHz Treatment time: 20-30 minutes

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    Short Wave Diathermy

    Pelvic organs are selectively heated usinginternal vaginal and rectal electrodes and canbe useful in pelvic inflammatory disease

    Avoid over metal implants (includingintrauterine devices) and electronic devicessuch as cardiac pacemakers, spinalstimulators, etc.

    Should not be used with a pregnant patient oroperator

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    Microwave

    Electromagnetic radiation at frequencies of

    915 and 2456 MHz

    Treatment time: 20-30 minutes

    Avoid near sensitive organs such as the

    eyes, testicles, brain, etc.

    Precaution over bony prominences due to

    reflection of the wave at the bone interfacemay produce increased heat absorption in

    the tissues superficial to the bone

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    Laser (non-surgical)

    A collimated (parallel waves of light) beam of

    photons of the same frequency with the

    waves in phase of lower level intensities

    Helium-neon, gallium-arsenide, etc.

    Usefulness anecdotal

    Utility unestablished

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    Heat Indications

    Pain

    Muscle spasm

    Decreases joint stiffness and contractures

    Myofascial pain and Fibromyalgia Production of hyperemia

    Acceleration of metabolic processes

    Hematoma resolution

    Bursitis and tenosynovitis

    Superficial thrombophlebitis

    Induction of reflex vasodilatation

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    Heat Contraindications/Precautions

    Acute inflammation, abscess, trauma, edemaor hemorrhage

    Bleeding disorders

    Insensitivity

    Inability to communicate or respond

    Poor thermal regulation

    Areas of malignancy Ischemia (Inadequate blood supply)

    Atrophic skin & Scar tissue

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    Superficial Cold - Cryotherapy

    Reduces blood flow

    Decreases metabolic activity

    Lessens muscle tone and spasm

    Decreases swelling

    Inhibits spasticity and clonus

    Increases gastrointestinal motility

    Slows nerve conduction Produces analgesia

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    Cryotherapy

    Restricted to superficial agents that areinexpensive, but effective including: ice, cold water, refrigerated units, vaporizing

    liquids (Vapo-Coolant spray), and chemical packs Chilling causes an initial period of

    vasoconstriction until subcutaneous tissuesreach 15o C

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    Cryotherapy

    Thereafter, vasodilatation occurs, howevervessels are still constricted compared tonormal

    Temperatures to 13 -15o C for 10 to 20minutes are used

    Cold should be provided just long enough toprevent swelling and bleeding but prolonged

    use should be avoided as cold can retardhealing

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    Cold Indications

    Musculoskeletal trauma

    Edema/hemorrhage control & analgesia

    Pain Muscle spasm

    Spasticity

    Adjunct in muscle re-education Reduction in metabolic activity

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    Cold Contraindications & Precautions

    Ischemia

    Cold intolerance/hypersensitivity

    Raynaud's Severe cold pressor responses

    Cold allergy

    Insensitivity

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    Electrotherapy

    Transcutaneous electrical stimulation andinterferential therapy are the two mostcommon forms of electrical stimulation usedfor pain modulation

    By varying parameters such as frequency,waveform, pulse duration, electrodeconfiguration, and duration of stimulus, arange of therapeutic effects is possible

    Both types of electrotherapy are thought tohave similar actions through segmentalinhibition or activation of descending pain-inhibitory systems

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    Electrotherapy

    Contraindications include pacemakers,myocardial disease, superficial metalimplants and over pharyngeal or laryngealmuscles

    There are many other forms of electricalstimulation including, H-Wave, diadynamiccurrent and various E-Stim devices

    None of these devices have been proven

    effective nor is there any evidence for adifference in outcome between differentelectrical stimulation forms

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    Electrical Stimulation Indications

    General Indications Pain Modulation: TENS, Interferential, H-wave

    Muscle Spasm: Produces muscle fatigue &relaxation

    Spasticity: Fatigue of the agonist, reciprocalinhibition

    Impaired Range of Motion: Used for mechanicalstretching

    Muscle Re-education: Training muscles torespond appropriately to volitional effort

    Disuse Atrophy & Strengthening: Does notstrengthen normal muscles more rapidly thantraditional approaches

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    Electrical Stimulation Indications

    Wound healing & Edema Reduction

    For immobilized and injured muscles, electricalstimulation maintains isometric strength and whenthere is splinting and pain, it may supplement

    volitional movements and speed of recovery Functional Electrical Stimulation (FES): In the

    upper motor neuron spinal cord injured patient,may increase strength, normalize blood pressure,allow for limited ambulation and lead to a sense of

    well-being FES also used for shoulder subluxation and

    dorsiflexion assist in gait training.

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    Transcutaneous Electrical Nerve

    Stimulation (TENS)

    A TENS unit produces analgesia in a widerange of medical conditions

    It is used in a self-administered setting after

    patient receives proper instructions TENS units are non-invasive, easy to use,

    safe and inexpensive

    TENS units are small simple devicesconsisting of a power source (rechargeablebattery), one or more signal generators and aset of electrodes

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    Transcutaneous Electrical Nerve

    Stimulation (TENS)

    Electrode placement and stimulationparameter remain more art than science

    High frequency (or conventional) TENS

    typically results in immediate pain relief thatlasts while the stimulus is on, but usuallyabates when the stimulation stops

    In acupuncture-like (or low frequency) TENS,the high stimulus intensity is painful and

    many patients cannot tolerate it but thebenefit is longer lasting pain relief

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    Interferential Therapy

    Interferential therapy involves a different formof electrical stimulation than TENS, althoughthe physiologic and therapeutic effects aresimilar in both

    Interferential is based on the principle that theinterference between two medium frequency(KHz) currents produces a low frequencycurrent that will be induced in the deep

    tissues

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    Interferential Therapy

    Therefore, interferential therapy allowseffective stimulation of deep tissues whereasTENS is predominantly a cutaneous orsuperficial stimulus

    Unlike the TENS unit, interferentialtreatments are usually provided directly by aphysical therapist

    Treatments involve the use of two pairs of

    electrodes and most units allow variation inwaveform, stimulus frequency and amplitudeor intensity

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    H-Wave Therapy

    The manufacturer lists H-Wave therapy as apowered muscle stimulator that at lowfrequency produces comfortable, rhythmic,

    non-fatiguing muscle contractions thatincrease local blood flow and lymphaticdrainage

    At high frequency, H-Wave therapy is

    purported to break the pain cycle similar toconventional TENS

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    Iontophoresis

    A process in which a continuous directcurrent is used to drive electrically chargedmolecules or atoms (ions) into the tissues

    Iontophoresis delivers high concentrates ofpolar substances, or medicinal agents, intothe skin, but to questionable depths

    The amount of medicine transferred throughthe skin is directly related to the duration of

    treatment, current density, and concentrationof the ions in the solution

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    Iontophoresis

    Indications for iontophoresis includemusculoskeletal inflammatory conditions,such as bursitis, and pain relief

    Common medications includedexamethasone, lidocaine andhydrocortisone

    Contraindications include impaired skinsensation, broken skin or bruises, and metal

    in or near the treatment area

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    Vibration

    Vibration is used for muscle facilitation and

    re-education and for acute and chronic pain

    conditions

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    Biofeedback

    Biofeedback is used to measure motor unitaction potentials (MUAP)

    The signals are detected, amplified and

    converted into audiovisual signals that areused to reinforce voluntary control

    The biofeedback signals, along with thepatient's voluntary effort, are used to either

    increase or decrease muscle activity Biofeedback has been successfully used for

    headaches and muscle tension

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    TractionApplication Techniques

    Manual

    Mechanical

    Free weights, pulley system

    Motorized

    Continuous

    Intermittent

    Gravity

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    Traction Parameters

    Cervical (25-30 pounds) Sitting versus supine

    20-30 degrees flexion

    Lumbar (50-100 pounds) Prone versus gravity inversion

    45-90 degrees hip flexion

    Continuous versus intermittent

    Duration 5-10 minutes herniated disc

    10-30 minutes other conditions

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    Traction Indications

    Degenerative disc disease

    Discogenic pain

    Herniated nucleus pulposus Radiculopathy

    Subacute or chronic joint pain

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    Traction Failures

    Inadequate weight

    Poor positioning

    Stretching of pain sensitive tissues

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    Traction Contraindications

    Spine instability, tumors/infections

    Vertebrobasilar disease - poor positioning

    Signs of myelopathy

    Significant osteopenia

    Lumbar traction in pregnant women

    Spondylolisthesis

    Extreme anxiety Restrictive lung disease

    Rheumatoid Arthritis

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    Compression

    Elevation

    String wrapping

    Ace wraps Garments

    Gradient pumps

    Physical activity and use

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    Orthotics

    Spine braces, corsets, collars, & supports

    Upper extremity slings, braces (dynamic andpassive), bands, supports

    Lower extremity braces, orthotics/braces Cushioning devices and pads

    Shoes, lifts & inserts

    Splints Static & Dynamic

    Mobility aids Canes, crutches, walkers, wheelchairs, scooters

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    Therapeutic Exercise

    Major factor in achieving long-term benefits in

    the treatment of chronic pain

    Patient may have had long period of

    decreased activity, weak muscles and

    contracted joints, which contribute to pain

    Exercise can decrease the pain cycle while

    improving cardiac and whole bodyconditioning

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    Therapeutic Exercise Objectives

    Decrease pain

    Improve mobility

    Strengthen weak muscles

    Increase flexibility

    Decrease mechanical stress

    Improve posture

    Stabilize hypermobile joints

    Improve fitness to prevent future injury

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    Therapeutic Exercise

    Aerobic exercise can slow the decrease of

    functional capacity in the elderly and

    recondition those that have been ill or have

    chronic disease

    Exercise may have a direct effect on pain

    management as evidence suggests that

    exercise can activate endogenous painmodulation systems

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    Therapeutic Exercise

    A therapeutic home exercise program shouldbe started early as part as the patient'soverall therapy program

    Initially, if the symptoms are acute, anexercise program may only include postureand body mechanics, positioning and basicstretching

    As the symptoms decrease the program

    should progress to more aggressive ROM,strengthening and functional activities

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    Therapeutic Exercise

    In the case of a chronic pain, the exerciseprogram should begin slowly due todeconditioning and pain compensations

    A home exercise program gives the patient asense of control over his or her therapy andprogress

    Emphasis should be placed on the benefits

    and the lifestyle changes that must be madeto incorporate a routine exercise programthroughout life

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    Aquatics Therapy

    Buoyancy allows aerobic exercise, range ofmotion and weight bearing that would not bepossible out of water

    Water can be soothing and relaxing andparticularly helpful to an anxious and fearfulpatient

    Short-term individual treatment should be

    followed by group classes and thereaftershould be carried out independently

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    Aquatics Therapy

    Therapy in warm water is beneficial for

    diagnoses such as:

    Fibromyalgia

    Myofascial Pain Syndrome

    Rheumatoid Arthritis

    Therapy in cool water is recommended for

    heat sensitive disorders such as multiplesclerosis

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    Physical & Occupational Therapy

    The therapist is a trained professional whoshould be recognized as a team member

    Communication between physician and

    therapist is key to achieving a successfuloutcome for the chronic pain patient

    The therapist sees the patient much morefrequently than the physician and may be

    able to provide important insights into bothphysical and psychosocial factors affectingthe patient's presentation

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    Therapy Prescription

    The therapy prescription should include ageneral order to evaluate and treat plus anylimitations or specifics requested by the

    physician The prescription should include the

    diagnosis, frequency and length ofrecommended treatment and most

    importantly, any precautions orcontraindications

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    FunctionallyOriented Therapy

    Therapy should be active and not passive

    Modalities may be useful early on but ingeneral should be discouraged in favor of

    therapy that is functionally oriented andsupports patient independence

    The patient must be encouraged to takecontrol of their therapy program and become

    an active participant Patient's participation in an exercise program

    is an important aspect of therapy

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    Manual Medicine

    Manual therapy refers to specific skills by the

    therapist in muscle, joint and somatic

    dysfunction

    As with any discipline, some therapists haveexceptional skills in this area

    Manual therapy is best utilized as an

    integrated part of a comprehensive treatmentprogram

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    Massage

    Reflex Effects Stimulation of peripheral receptors in the skin

    produce centrally mediated sensations of pleasureand peripherally cause muscle relaxation

    Mechanical Effects Consists of measures to assist return flow

    circulation of blood and lymph and measures thatproduce intramuscular motion to stretchadhesions and mobilize fluid accumulation

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    Massage

    Techniques Includes stroking (effleurage), compression

    (ptrissage), friction/deep massage andpercussion/clapping (tapotement)

    Indications Include any condition in which relief of pain,

    reduction of swelling, or mobilizing of contractedtissue is desired

    Contraindications Include infections, thrombophlebitis, malignancies,

    burns, and in skin diseases

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    Myofascial Release & Stretching

    Myofascial release involves active orvoluntary muscle contraction along withpassive massage

    A highly interactive stretching technique thatrequires feedback from the patient's body todetermine the direction, force and duration ofthe stretch and to facilitate maximumrelaxation of the tight or restricted tissues

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    Other StretchingTechniques

    Progressive stretch mobilization

    Sustained progressive stretch

    Spray and stretch

    Muscle energy

    Strain-Counterstrain

    Rolfing

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    Mobilization

    Mobilization includes those manualprocedures which attempt to increase jointrange of motion beyond the resistance barrier

    which limits passive range of motion orexercise

    May involve either an accessory glide of thejoint or a physiologic movement of the joint

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    Mobilization

    Rhythmic repetitions with minimal force mayprovide pain relief

    Differs from manipulation or adjustment by

    the absence of a forceful thrust or jerkingmovement

    Maitland's grades of mobilization: Grade I -Grade IV

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    Manipulation

    Thrusting techniques: Application of a high-

    velocity, low-amplitude thrust to a joint

    Forces the joint beyond the physiologic range

    of movement to the anatomical limits ofmotion

    Contraindications: osteoporosis, acute

    inflammation, infection, tumor, structuralinstability, Vertebrobasilar insufficiency

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    Ergonomics

    Ergonomics is the study of how peopleinteract with their physical environment, andmodifications to prevent/reduce

    musculoskeletal disorders The ergonomic system model consists of four

    parts; the task, the operator, the environmentand the equipment

    The objective is to maximize systemperformance while minimizing mismatchesbetween system elements

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    Ergonomics

    Basic ergonomic principles include keepingthe wrists straight and the elbows down,minimizing spine twisting and bending and

    providing adjustable chairs and/or worksurfaces

    Ergonomic redesign requirements includereduction of forces, frequency of activities,

    holding time, prolonged static posturing andextreme postural deviations

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    Functional Restoration Approaches

    Structured group physical conditioning

    Regular sessions of stretching, strengthening,aerobic conditioning plus educationalactivities & work simulation

    Dependency on the therapist is discouragedand the program is geared towards healthybehaviors and return to leisure and workactivities

    The group setting provides friendship andencourages mutual support

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    WorkHardening vs Conditioning

    Work hardening involves specific simulated work

    activities prior to returning to employment

    Work toughening or conditioning where the

    individual exercises in a gym is not work hardening While work hardening may include gym exercise

    activities, the program is task specific for the

    particular job and involves both emotional and

    physical reactivation to meet job demands

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    Comprehensive Pain Programs

    Multidisciplinary, coordinated painmanagement is based on viewing chronicpain treatment from a biopsychosocial model

    rather than from a traditional biomedicaltreatment approach

    The goal is to assist the individual inmanaging pain and returning to a functional

    lifestyle including re-engaging in personaland work activities

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    Comprehensive Pain Programs

    The biomedical model focuses on "fixing"physical pathology and curing the painthrough various interventions

    The biopsychosocial model of painmanagement acknowledges the role ofphysical pathology while realizing thatpsychological, social and cultural issues play

    a major role in how individuals perceive andreact to painful stimuli

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    Pain Program Goals

    Reducing the misuse of medications andexcessive invasive medical procedures

    Maximizing & maintaining physical activityand returning the individual to productiveactivity at home, socially and/or at work

    Increasing the patients ability to managepain and related problems while reducingsubjective pain intensity

    Strong emphasis is placed on increasing thelevel of function and ability to manage painand related problems, even without reductionof subjective pain intensity

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    Pain Program Modalities

    Medication management

    Physical and Occupational therapy

    Behavioral-psychological therapy

    Vocational and disability management

    Adjunctive treatment modalities such as

    trigger point injections, nerve blocks and

    various invasive interventions

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    Fitness Programs

    Supervised low-cost gym program at thephysical therapy center This program is ideal as the patient can be

    weaned early from one-on-one physical therapy to

    independent use of the gym facility Less costly, yet the patient is still in a protected

    and supervised environment

    Private gym or fitness center

    To prevent re-injury, patients should not start sucha program without specific directions from thephysician or physical therapist

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    Vocational Rehabilitation

    For chronic pain patients who have return togainful employment as a reasonable goal,vocational rehabilitation efforts should be anintegral part of pain management and such

    efforts should start early in the rehabilitationprocess

    Resources such as Workers' Compensationor State Vocational Rehabilitation Services

    should be identified

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    Vocational Rehabilitation

    Employers should be encouraged to makereasonable accommodations and considerreturn to work for the patient in modifiedand/or part time positions

    Volunteer activities allow many individuals tohave meaningful interactions with otherpeople, stay busy, get out of the home, andmake a worthwhile social contribution

    A i l R i l I

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    Avocational & Recreational Issues

    Recreational activities can be pleasurable,

    time filling, socially reinforcing as well as both

    physically and mentally therapeutic

    P G idi P i i l

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    PM&R Guiding Principles

    Do no harm

    Biopsychosocial model

    Diagnose and then treat

    Cost-effective care Pain control

    Appropriate use of assistive devices

    Patient empowerment Functional restoration

    Return to work & leisure activities