PERSONAL INFORMATION Apostolos Karligkiotis Via Giusti · PDF filePERSONAL INFORMATION...

Curriculum Vitae

PERSONAL INFORMATION Apostolos Karligkiotis

Via Giusti 8, 21100 Varese (Italy)

00390332278426

[email protected]

Sex Male | Date of birth 20/02/1979 | Nationality Greek

EDUCATION AND TRAINING

01 September 1995–30 July 1996 Greek High School Diploma (Apolytirio)at the “3rd General High School”, Volos (Greece)

Grade: 16/20

01 October 2003–15 December 2008

Active Internship as a Medical Student. (Annual Internship for 5 years)Department of Otorhinolaryngology - Ospedale di Circolo e Fondazione Macchi, Varese, Italy (Chief: Prof. Paolo Castelnuovo), Varese (Italy)

Rhinology and endoscopic sinonasal and skull base surgery


Medical DegreeUniversity of Insubria, Varese (Italy)

Grade: 90/110

Thesis: “Sinonasal Inverted Papilloma: Current diagnostic concepts and treatment”. Supervisor: Prof. P. Castelnuovo, Assistant Supervisor: Prof. G. Tomei.

18 December 2008–31 March 2009

Active Internship as a Medical Doctor Attender.Department of Otorhinolaryngology - Ospedale di Circolo e Fondazione Macchi (Chief: Prof. Paolo Castelnuovo), Varese (Italy)


01 April 2009–30 June 2009 Post-diploma internship at a GP and at the Department of Internal Medicine and Thoracic SurgeryAzienda Ospedaliera “Ospedale di Circolo e fondazione Macchi” - Università dell'Insubria., Varese (Italy)

01 July 2009–17 July 2009 Medical practitioner licenseUniversity of Insubria, Varese (Italy)

Grade: 238,5/270.

18 July 2009–31 October 2009 Active Internship as a Medical Doctor Attender.Department of Otorhinolaryngology - Ospedale di Circolo e Fondazione Macchi (Chief: Prof. Paolo Castelnuovo), Varese (Italy)


01 November 2009–31 July 2010 ScholarshipUniversity of Insubria, Varese (Italy)

1.4.14 © European Union, 2002-2014 | http://europass.cedefop.europa.eu / 13

Curriculum Vitae Apostolos Karligkiotis

Research activity regarding “The infections in Otorhinolaryngology” at the Department of Otorhinolaryngology - Ospedale di Circolo e Fondazione Macchi, Varese, Italy (Chief: Prof. Paolo Castelnuovo).

Rhinosinusitis

01 August 2010–30 June 2011 Active Internship as a Medical Doctor AttenderDepartment of Otorhinolaryngology - Ospedale di Circolo e Fondazione Macchi, Varese, Italy (Chief: Prof. Paolo Castelnuovo), Varese (Italy)


01 July 2011–Present ResidentResidency programme of Otorhinolaryngology of the University of Sassari, at the Department of Otorhinolaryngology of the Azienda Ospedaliero Universitaria di Sassari (Chief: Prof. Francesco Meloni), Sassari (Italy)


Residency RotationDepartment of Otorhinolaryngology - Ospedale di Circolo e Fondazione Macchi (Chief: Prof. Paolo Castelnuovo), Varese (Italy)

As part of the Residency Educational Network Aggreement between the Univesity of Sassari, Italy and the Department of Otorhinolaryngology of Varese, Italy.


05 March 2012–01 June 2012 Residency RotationDepartment of Otorhinolaryngology - Ospedale di Circolo e Fondazione Macchi (Chief: Prof. Paolo Castelnuovo), Varese (Italy)



18 June 2012–07 July 2012 Skull base and Microneurosurgical ClerkshipSkull Base Lab (Program Director: Prof. Antonio Bernardo) of the Department of Neurological Surgery (Chairman: Prof. Philip E. Stieg), New York (United States)

at Weil Cornell Medical College of Cornell University – New York Presbyterian Hospital.

Endoscopic and lateral skull base surgery





04 February 2013–27 February 2013

ObservershipHead and Neck Service (Chief: Prof. Jatin Shah) of the Departement of Surgery at Memorial Sloan Kettering Cancer Center, New York (United States)

Head and Neck Oncology and Surgery



04 March 2013–27 June 2013 Erasmus Student Placement programme for residentsService ORL (Chief: Prof. Philippe Herman) at Hopital Lariboisière, Paris (France)






17 March 2014–Present Residency RotationDepartment of Otorhinolaryngology - Ospedale di Circolo e Fondazione Macchi (Chief: Prof. Paolo Castelnuovo), Varese (Italy)



PERSONAL SKILLS

Mother tongue(s) Greek

Other language(s) UNDERSTANDING SPEAKING WRITING

Listening Reading Spoken interaction Spoken production

Italian C2 C2 C2 C2 C2

Medical Degree at the University of Insubria-Varese, Italy

English C1 C1 C1 C1 C1

First Certificate in English

French A2 A2 A2 A2 A1

Spanish A2 A2 A2 A2 A1

Levels: A1/A2: Basic user - B1/B2: Independent user - C1/C2: Proficient userCommon European Framework of Reference for Languages

Computer skills good command of office suite as well as photo and movie editing in both mac os and windows environment

ADDITIONAL INFORMATION

Publications A) Articles in peer reviewed indexed journals

1. Limitations and complications of endoscopic surgery for treatment for sinonasal inverted papilloma: A reassessment after 212 cases. Lombardi D, Tomenzoli D, Buttà L, Bizzoni A, Farina D, Sberze F, Karligkiotis A, Castelnuovo P, Nicolai P. Head Neck. 2011 Aug;33(8):1154-1161. ISSN: 10433074. DOI: 10.1002/hed.21589. PubMed ID: 20967873.Impact Factor: 2.833

2.Fronto-ethmoidal and intraorbital osteomas: exploring the limits of the endoscopic approach. Turri-Zanoni M, Dallan I, Terranova P, Battaglia P, Karligkiotis A, Bignami M, Castelnuovo P. Arch Otolaryngol Head Neck Surg. 2012 May;138(5):498-504. ISSN: 08864470. DOI: 10.1001/archoto.2012.644. PubMed ID: 22652949.Impact Factor: 1.779


http://europass.cedefop.europa.eu/en/resources/european-language-levels-cefr


3. Monostotic Fibrous Dysplasia of the Inferior Turbinate. Karligkiotis A, Terranova P, Dallan I, Castelnuovo P. Otolaryngol Head Neck Surg. 2012 Jun;146(6):1035-6.ISSN: 01945998. DOI: 10.1177/0194599811431059. PubMed ID: 22157265. Impact Factor: 1.625

4. Endoscopic transnasal intraorbital surgery: our experience with 16 cases. Castelnuovo P, Dallan I, Locatelli D, Battaglia P, Farneti P, Tomazic PV, Seccia V, Karligkiotis A, Pasquini E, Stammberger H. Eur Arch Otorhinolaryngol. 2012 Aug;269(8):1929-35. ISSN: 09374477. DOI: 10.1007/s00405-011-1917-z. PMID: 22237761. Erratum in: Eur Arch Otorhinolaryngol. 2012 Aug;269(8):1937.ISSN: 09374477. DOI: 10.1007/s00405-012-1987-6. PMID: 22237761. Impact Factor: 1.458

5. Radiology quiz case 1: Unicystic ameloblastoma. Volpi L, Ferreli F, Karligkiotis A, Pistochini A, Meloni F, Castelnuovo P. Arch Otolaryngol Head Neck Surg. 2012 Oct;138(10):973-974. ISSN: 08864470. DOI: 10.1001/2013.jamaoto.57. PMID: 23069829. Impact Factor: 1.779

6. Necrotizing Cranio-Cervical Soft Tissue Infections: Clinical Experience and Personal Considerations. Gallo S, Karligkiotis A, Lenzi R, Castelnuovo P, Dallan I. Case Report Otolaryngol. 2012;2012:489638. DOI: 10.1155/2012/489638. PMID: 23304596.

7. A rare localization of actinomycosis mimicking ulcerative malignancy. Volpi L, Ferreli F, Bignami M, Pistochini A, Meloni F, Karligkiotis A, Castelnuovo P. Case Report Otolaryngol. 2013;2013:323210. DOI: 10.1155/2013/323210. PMID: 23533886.

8. Pediatric follicular dendritic cell sarcoma of the head and neck. A case report and review of the literature. Karligkiotis A, Contis D, Bella M, Machouchas N, Volpi L, Melis A, Meloni F. Int J Ped Otorhinolaryngol. 2013 Jul;77(7):1059-1064. DOI: 10.1016/j.ijporl.2013.04.015. PMID: 23684177. Impact Factor: 1.35

9. A novel endoscopic technique for long term patency of cholesterol granulomas of the petrous apex. Terranova P, Karligkiotis A, Gallo S, Meloni F, Bignami M, Castelnuovo P. Laryngoscope. 2013 Nov;123(11):2639-2642. DOI: 10.1002/lary.24170. PMID: 23686691. Impact Factor: 1.979

10. Primary orbital eosinophilic angiocentric fibrosis with intranasal extension. Karligkiotis A, Volpi L, Ferreli F, Cerati M, Kagkelari E, Meloni F, Castelnuovo P. Head Neck. 2014 Jan;36(1):E8-E11. DOI: 10.1002/hed.23396. PMID: 23733241. Impact Factor: 2.833

11. Oncocytic Schneiderian papillomas: Clinical behaviour and outcomes of the endoscopic endonasal approach in 33 cases. Karligkiotis A, Bignami M, Terranova P, Gallo S, Meloni F, Padoan G, Lombardi D, Nicolai P, Castelnuovo P. Head Neck. 2013 Apr 18. DOI: 10.1002/hed.23341. PMID: 23595801. Impact Factor: 2.833 (accepted - in press)

12. Head and neck cancer epidemiology in north Sardinia, Italy. Karligkiotis A, Machouchas N, Bozzo C, Melis A, Cossu A, Budroni M, Palmieri G, Bernardini E, Volpi L, Meloni F. Acta Medica Mediterranea. 2014 Jan;30(1):41-47. Impact Factor: 1.053

13. How to prevent diplopia in endoscopic transnasal resection of tumors involving the medial orbital wall. Karligkiotis A, Ciniglio Appiani M, Verillaud B, Herman P. Laryngoscope. 2014 Feb 27. DOI: 10.1002/lary.24657. PMID: 24577882. Impact Factor: 1.979 (accepted - in press)

14. How to avoid mucocele formation under pedicled nasoseptal flap. Karligkiotis A, Meloni F, Herman P, Castelnuovo P. Am J Otolaryngol. 2014. Impact Factor: 1.228 (accepted - in press)

B) Articles in peer reviewed non indexed journals

1. Raccomandazioni cliniche sulla gestione delle epistassi (Clinical recommendations for management of epistaxis – Guidelines from the Italian Society of Otorhinolaryngology-Head and Neck Surgery). A. Campanini, C. Vicini, M. Benazzo, M. Bignami, P. Castelnuovo, ML. Fiorella, R. Fustos, M. Magnani, L. Manzari, F. Pagella, A. Vandelli, M. Vigili, G. Villari, U. Barbone, F. Basilico, P. Battaglia, C. Biasoli , L.Califano, C. Cambria, Pietro Canzi, F. Chu, A. Colombo, G. Craparo, G. D’Agostino C. Danesino, F. De Bernardi, G. Delù, D. Di Maria, I. Ermoli, F. Ferreli, M. Ferrini, R. Fiorella, S. Gallo, A. Karligkiotis, F. Lamanna , B. Mafera, E. Matti, G. Padoan, F. Pieri, A. Pistochini, M. Rebecchi, A. Ricci Maccarini, G. Romano, F. Sberze, F. Simoncello, M. Stacchini, P. Terranova, R. Zaccari. Argomenti di Acta Otorhinolaryngologica Italica. 2010;4(1):1-28.

2. Ostruzione respiratoria nasale monolaterale: un caso insolito (Unilateral nasal obstruction: an unsual case). A. Karligkiotis, S. Gallo, R. Lenzi, P. Castelnuovo, I. Dallan. Argomenti di Acta Otorhinolaryngologica Italica. 2013;7(1):8-9.



C) Book Chapters

1. Tumor specific strategies: Inverted papilloma. P. Castelnuovo, A. Karligkiotis, P. Battaglia, F. Sberze, D. Lombardi, P. Nicolai. In: Draf W. et al. (eds): Interdisciplinary Endonasal Endoscopic Surgery of Skull Base Tumors. Georg Thieme Verlag, Stuttgard – New York, 2014 (in press)

2. The treatment of inverted papilloma at the skull base. P. Castelnuovo, A. Karligkiotis, S. Gallo, F. Meloni, D. Lombardi, P. Nicolai. In: de Souza C. (ed): Head and Neck Surgery (Vol 1 and 2). Second edition. Jaypee Brothers Medical Publishers (P) Ltd, New Delhi, 2014 (in press)

D) Articles in Congress acts

- Italian Congresses

1. Il trattamento chirurgico della patologia del seno frontale (The surgical treatment of the frontal sinus’ disease). Bignami M, Delù G, Padoan G, De Bernardi F, Simoncello F, Bossolesi P, Latorre P, Cambria C, Pistochini A, Battaglia P, Karligkiotis A, Castelnuovo P. In: Atti del Convegno: Le nuove tecnologie nella chirurgia endoscopica nasosinusale. Ed.: Carlucci C, Fasanella L. Civitanova Marche, 20 Novembre 2004, pg. 95-124.

- International Congresses

1. Multi-layer centripetal technique in endoscopic trearment of inverted papilloma. P. Castelnuovo, Delù G, Tomenzoli D, Karligkiotis A, Nicolai P. In: Atti del congresso: CIRAS 11 (Croato-Italian Rhinosurgical Advanced School) – Zagreb, Croatia, 15-16 Settembre, 2006. pg. 48-53.

E) Abstracts in Congress Abstract Book

- International Congresses

a) Oral communications

1. “Extreme” inverted papillomas. Decision making and treatment options. Delù G, Karligkiotis A, Simoncello F, Palma P, Sberze F, Castelnuovo P. Eur Arch Otorhinolaryngol. (2007) (Suppl 1) 264:S265-S354:S276, Springer-Verlag Ed. 2007. Communication.

2. How to Preserve Nasal Mucosa: The Balloon Sinusoplasty Technique. G. Padoan, I. Ermoli, A. Karligkiotis, S. Gallo, P. Castelnuovo. In: Abstract Book: 7th Pan ARABFOS Conference and 8th Saudi International ORL-H&N Surgery Conference. Dammam, Saudi Arabia, 22-24 March, 2011. Communication.

3. The Employment of an Ethmoidal Implantable Device: A Prospective Study. G. Padoan, S. Gallo, I. Ermoli, E. Digilio, A. Karligkiotis, P. Castelnuovo. In: Abstract Book: 7th Pan ARABFOS Conference and 8th Saudi International ORL-H&N Surgery Conference. Dammam, Saudi Arabia, 22-24 March, 2011. Communication.

4. Critical Areas in the Surgical Management of Sinonasal Inverted Papillomas. A. Karligkiotis, S. Gallo, F. Sberze, E. Digilio, P. Terranova, P. Castelnuovo. In: Abstract Book: 1st Congress of the Confederation of the European ORL-HNS and 62 National Congress of the Spanish Society of ORL-HNS. Barcelona, Spain, 2-6 July, 2011. Communication.



5. The Role of Combined Medical and Surgical Treatment of Chronic Rhinosinusitis in Children Affected by Cystic Fibrosis. S. Gallo, G. Padoan, E. Digilio, A. Karligkiotis, F. Basilico, P. Castelnuovo. In: Abstract Book: 1st Congress of the Confederation of the European ORL-HNS and 62 National Congress of the Spanish Society of ORL-HNS. Barcelona, Spain, 2-6 July, 2011. Communication.

6. Optic Nerve Decompression in Traumatic Optic Neuropathy: Surgery or Medical Treatment? Our Experience. E. Digilio, E. Emanuelli, F. Simoncello, S. Gallo, A. Karligkiotis, P. Castelnuovo. In: Abstract Book: 1st Congress of the Confederation of the European ORL-HNS and 62 National Congress of the Spanish Society of ORL-HNS. Barcelona, Spain, 2-6 July, 2011. Communication.

7. Where do we stand on choanal atresia? A 15-year experience. Karligkiotis A, Gallo S, Zappoli F, Digilio E, Turri-Zanoni M, Padoan G, Meloni F, Castelnuovo P. In: Abstract Book: 5th World Congress for Endoscopic Surgery of the Brain, Skull Base & Spine, combined with The First Global Update on FESS, the Sinuses & the Nose. Vienna, Austria, 29 March - 1 April, 2012. Communication.

8. Skull base defects in children: Eleven years experience of pediatric duraplasty. Karligkiotis A, Gallo S, Zocchi J, Bernardini E, Turri-Zanoni M, Pistochini A, Meloni F, Castelnuovo P. In: Abstract Book: 5th World Congress for Endoscopic Surgery of the Brain, Skull Base & Spine, combined with The First Global Update on FESS, the Sinuses & the Nose. Vienna, Austria, 29 March - 1 April, 2012. Communication.

9. Are far lateral frontal sinus osteomas still a contraindication for the pure endoscopic endonasal approach? Turri-Zanoni M, Battaglia P, Terranova P, Dallan I, Gallo S, Karligkiotis A, Bignami M, Castelnuovo P. In: Abstract Book: 5th World Congress for Endoscopic Surgery of the Brain, Skull Base & Spine, combined with The First Global Update on FESS, the Sinuses & the Nose. Vienna, Austria, 29 March - 1 April, 2012. Communication.

10. Endoscopic endonasal management of pediatric benign tumors of the nose and paranasal sinuses. Turri-Zanoni M, Padoan G, Gallo S, Sica E,Karligkiotis A, Volpi L, Ferreli F, Castelnuovo P. In: Abstract Book: 5th World Congress for Endoscopic Surgery of the Brain, Skull Base & Spine, combined with The First Global Update on FESS, the Sinuses & the Nose. Vienna, Austria, 29 March - 1 April, 2012. Communication.

11. Robotic-assisted dissection of posterior ventral skull base: preliminary preclinical impressions and critical considerations. Battaglia P, Dallan I, Vicini C, Montevecchi F, Karligkiotis A, Turri-Zanoni M, Castelnuovo P, Tschabitscher M. In: Abstract Book: 5th World Congress for Endoscopic Surgery of the Brain, Skull Base & Spine, combined with The First Global Update on FESS, the Sinuses & the Nose. Vienna, Austria, 29 March - 1 April, 2012. Communication.

12. Endoscopic transnasal management of intraorbital lesions: our personal experience. Ferreli F, Karligkiotis A, Turri-Zanoni M, Dallan I, Locatelli D, Castelnuovo P. In: Abstract Book: 24th Congress of the European Rhinologic Society and 31st International Symposium of Infection & Allergy of the Nose. Toulouse, France, 17-21 June, 2012. Communication.

13. Endoscopic skull base reconstruction: Lessons learned with 420 cases. Gallo S, Karligkiotis A, Turri-Zanoni M, Volpi L, Pistochini A, Castelnuovo P. AAO-HNSF Annual Meeting & OTO EXPO. Washington, DC, USA, 9-12 September 2012. Communication.

14. Endoscopic endonasal resection of adenoid cystic carcinoma: our experience from a series of 28 cases. Volpi L, Turri-Zanoni M, Bignami M, Lepera D, Karligkiotis A, Ferreli F, Bolzoni-Villaret A, Nicolai P, Castelnuovo P. In: Abstract Book: 2nd Meeting of European Academy of ORL-HNS and CE ORL-HNS. Nice, France, 27-30 April, 2013. Communication.

15. Quality of life following endoscopic endonasal resection of anterior skull base cancers. Lepera D, Turri-Zanoni M, Battaglia P, Bolzoni-Villaret A, Bignami M, Karligkiotis A, Volpi L, Nicolai P, Castelnuovo P. In: Abstract Book: 2nd Meeting of European Academy of ORL-HNS and CE ORL-HNS. Nice, France, 27-30 April, 2013. Communication.

b) Posters

1. Optic nerve decompression in traumatic optic neuropathy: surgery or medical treatment? Our experience. Ferreli F, Digilio E, Emanuelli E, Gallo S, Turri-Zanoni M, Tafili R, Karligkiotis A, Castelnuovo P. In: Abstract Book: 5th World Congress for Endoscopic Surgery of the Brain, Skull Base & Spine, combined with The First Global Update on FESS, the Sinuses & the Nose. Vienna, Austria, 29 March - 1 April, 2012. Poster.

2. Midline Nasal Dermoid Sinus Cysts: Extension-Oriented Surgical Strategy. Karligkiotis A, Volpi L, Ferreli F, Gallo S, Palma P, Castelnuovo P. In: Abstract Book: Nose & Face World Rome 2012. VII International Congress of the International Federation of Facial Plastic Surgery Societies (IFFPSS),



Rome, Italy, 9-12 May, 2012. Poster.

3. Anterior ethmoidal artery septal flap for the management of septal perforation. Ferreli F, Volpi L, Karligkiotis A, Khodaei I, Palma P, Castelnuovo P. In: Abstract Book: Nose & Face World Rome 2012. VII International Congress of the International Federation of Facial Plastic Surgery Societies (IFFPSS), Rome, Italy, 9-12 May, 2012. Poster.

4. Oncocytic Schneiderian papilloma: Is it really more aggressive than Inverted papilloma? Karligkiotis A, Gallo S, Volpi L, Turri-Zanoni M, Lepera D, Meloni F, Nicolai P, Castelnuovo P. In: Abstract Book: 2nd Meeting of European Academy of ORL-HNS and CE ORL-HNS. Nice, France, 27-30 April, 2013. Poster.

5. Occupational hazards in patients treated for epithelial sinonasal cancers: Our experience. Turri-Zanoni M, Bonzini M, Battaglia P, Volpi L, Lepera D, Karligkiotis A, Ferrario M, Castelnuovo P. In: Abstract Book: 2nd Meeting of European Academy of ORL-HNS and CE ORL-HNS. Nice, France, 27-30 April, 2013. Poster.

- Italian Congresses

a) Oral communications

1. Trattamento dei mucoceli sfenoidali isolati in Day Surgery (Treatment of isolated sphenoidal mucoceles in Day Surgery). G. Delù, F. De Bernardi, A. Karligkiotis. In: Abstract Book: 91° Congresso Nazionale SIO e CCF. Torino, 26-29 Maggio, 2004. Communication.

2. P. Terranova, A. Karligkiotis, S. Gallo, F. Basilico, P. Battaglia, M. Bignami, P. Castelnuovo. Granuloma Colesterinico dell’Apice Petroso: Nuova “Tattica” Chirurgica. 97°Difetti Congeniti del Basicranio: Le Malformazioni della Linea Mediana (Congenital diffects of the skull base: Midline nasal lesions). A. Karligkiotis, S. Gallo, P. Terranova, L. Volpi, F. Sberze, P. Castelnuovo. In: Abstract Book: XI Congresso Nazionale SIB - Società Italiana Basicranio, “Alla Ricerca di Scelte Terapeutiche Condivise”. . Poster. Verona, 25-27 Novembre, 2010. Communication.

3.Patologia Malformativa del Seno Sfenoidale: La Persistenza del Canale Cranio-Faringeo di Sternberg (Sphenoidal sinus malformative disease: the persistance of Sternberg’s cranio.pharyngeal canal). S. Gallo, M. Turri Zanoni, F. De Bernardi, A. Karligkiotis, A. Pistochini, P. Castelnuovo. In: Abstract Book: XI Congresso Nazionale SIB - Società Italiana Basicranio, “Alla Ricerca di Scelte Terapeutiche Condivise”. Verona, 25-27 Novembre, 2010. Communication.

4. Trattamento Endoscopico Endonasale delll’Estesioneuroblastoma: La Nostra Esperienza. (Endoscopic endonasal treatment of esthesioneuroblastoma: Our experience) L. Volpi, A. Karligkiotis, P. Battaglia, S. Gallo, A. Bolzoni, P. Nicolai, P. Castelnuovo. In: Abstract Book: XI Congresso Nazionale SIB - Società Italiana Basicranio, “Alla Ricerca di Scelte Terapeutiche Condivise”. Verona, 25-27 Novembre, 2010. Communication.

5. La ricostruzione endoscopica endonasale del basicranio: Insegnamenti ed accorgimenti tecnici appresi dall’esperienza su 420 casi trattati (Endoscopic endonasal skull base reconstruction: Lessons and technical precautions learned with 420 cases treated). A. Karligkiotis, S. Gallo, F. Ferreli, L. Volpi, E. Bernardini, M. Turri Zanoni, G. Padoan, F. Meloni, P. Castelnuovo. In: Abstract Book: XII Congresso Nazionale SIB - Società Italiana Basicranio, “Integrazione terapeutica per l’ottimizzazione dei risultati”. Novara, 29-30 Novembre, 2012. Communication.

6. La neuronavigazione nella chirurgia endoscopica transnasale (Neuronavigation in endoscopic transnasal surgery). L. Volpi, M. Bignami, A. Pistochini, F. Ferreli, D. Lepera, A. Karligkiotis, M. Turri Zanoni, F. Meloni, P. Castelnuovo. In: Abstract Book: XII Congresso Nazionale SIB - Società Italiana Basicranio, “Integrazione terapeutica per l’ottimizzazione dei risultati”. Novara, 29-30 Novembre, 2012. Communication.

7. Resezione endoscopica dei tumori benigni naso-sinusali: indicazioni, technica chirurgica e risultati a lungo termine (Endoscopic resection of benign sinonasal tumors: indications, surgical technique and long-term results). Bignami M, Terranova P, Turri-Zanoni M, Sica E, Digilio E, De Bernardi F, Karligkiotis A, Castelnuovo P. In: Abstract Book: 100° Congresso Nazionale SIO e CCF. Roma, 28-31 Maggio, 2013. Communication.



b) Posters

1. Granuloma colesterinico dell’apice petroso: nuova “tattica” chirurgica (Cholesterol granuloma of the petrous apex: new surgical “strategy”). P. Terranova, A. Karligkiotis, S. Gallo, F. Basilico, P. Battaglia, M. Bignami, P. Castelnuovo. In: Abstract Book: 97° Congresso Nazionale SIO e CCF. Riccione, 19-22 Maggio, 2010. Poster. Winner Best Poster.

2. Schwannoma Nasosinusale: “business plan” (Sinonasal Schwannoma: “business plan”). S. Gallo, A. Karligkiotis, P. Terranova, F. Basilico, E. Sica, P. Battaglia, M. Bignami, P. Castelnuovo. In: Abstract Book: 97° Congresso Nazionale SIO e CCF. Riccione, 19-22 Maggio, 2010. Poster.

3. Lesioni intraorbitarie: L’approccio endoscopico transnasale è ancora un avatar? (Intraorbital lesions: Is the transnasal endoscopic approach still an avatar?) A. Karligkiotis, P. Terranova, M. Turri Zanoni, S. Gallo, E. Digilio, F. Basilico, G. Padoan, A. Pistochini, P. Castelnuovo. In: Abstract Book: 98° Congresso Nazionale SIO e CCF. Udine, 25-28 Maggio, 2011. Poster.

4. Ritorno al futuro: La resezione endoscopica delle recidive nasofaringee (Back to the future: The endoscopic resection of nasopharyngeal recurrences). S. Gallo, A. Karligkiotis, M. Turri Zanoni, P. Terranova, L. Volpi, P. Battaglia, M. Bignami, P. Nicolai, P. Castelnuovo. In: Abstract Book: 98° Congresso Nazionale SIO e CCF. Udine, 25-28 Maggio, 2011. Poster. Winner Best Poster.

5. Valutazione di Merocel® Hemox, Merocel® 2000 e Mondocel® Standard nel tamponamento nasale dopo chirurgia endoscopica funzionale nasosinusale: uno studio prospettico randomizzato (Evaluation of Merocel® Hemox, Merocel® 2000 and Mondocel® standard during nasal packing removal after functional endoscopic sinus surgery: a prospective randomized study). A. Melis, A. Karligkiotis, L. Volpi, P. Pastiglia, F. Meloni. In: Abstract Book: 99° Congresso Nazionale SIO e CCF. Bari, 23-26 Maggio, 2012. Poster.

5. Linfoma MALT familiare della testa e del collo: 2 casi clinici (Familial MALT linfoma of the head and neck: 2 clinical cases). A. Melis, L.M. De Luca, V. Fancello, A. Karligkiotis, F. Meloni. In: Abstract Book: 99° Congresso Nazionale SIO e CCF. Bari, 23-26 Maggio, 2012. Poster.

6.Diagnosi e trattamento di un caso di paraganglioma vagale (Diagnosis and treatment of a vagal paraganglioma). A. Melis, V. Fancello, L.M. De Luca, A. Karligkiotis, F. Meloni. In: Abstract Book: 99° Congresso Nazionale SIO e CCF. Bari, 23-26 Maggio, 2012. Poster.

7.Fistole rinoliquorali post-traumatiche: indicazioni e limiti della chirurgia endoscopica endonasale (Post-traumatic CSF-leaks: indications and limits of the endoscopic endonasal approach). S. Gallo, J. Zocchi, M. Turri-Zanoni, A. Karligkiotis, P. Castelnuovo. In: Abstract Book: 99° Congresso Nazionale SIO e CCF. Bari, 23-26 Maggio, 2012. Poster.

c) Videos

1. Corridoi chirurgici endoscopici transnasali al basicranio: La chirurgia multiporte (Surgical endoscopic transnasal corridors to the skull base: The multiportal technique). Gallo S, Turri-Zanoni M, Preti A, Lepera D, Karligkiotis A, Pistochini A, Bignami M, Castelnuovo P. In: Abstract Book: 100° Congresso Nazionale SIO e CCF. Roma, 28-31 Maggio, 2013. Video.

2. Angiofibromi con estensione laterale: Indicazioni e limiti della chirurgia endoscopica transnasale (Angiofibromas with lateral extension: Indications and limits of the transnasal endoscopic surgery). Turri-Zanoni M, Sica E, Terranova P, Gallo S, Karligkiotis A, Volpi L, Bignami M, Castelnuovo P. In: Abstract Book: 100° Congresso Nazionale SIO e CCF. Roma, 28-31 Maggio, 2013. Video.

F) Multimedial Pubblications – CD

1. P. Castelnuovo, M. Bignami, P. Battaglia, S. Gallo, A. Karligkiotis, S. Mauri, F. Simoncello, P. Terranova. In: Cosa fare in caso di: Flogosi Rinosinusale. Vol. 1 (What to do in case of: sinonasal inflammatory disease. Vol. 1) - Collana di Aggiornamento Scientifico. A cura del Prof. Paolo Castelnuovo. GlaxoSmithKline SpA; 2011. Multimedial CD.

2. P. Castelnuovo, M. Bignami, P. Battaglia, S. Gallo, A. Karligkiotis, S. Mauri, F. Simoncello, P.



Terranova. In: Cosa fare in caso di: Tumori Benigni Rinosinusali. Vol. 2 (What to do in case of: benign sinonasal tumors. Vol. 2) - Collana di Aggiornamento Scientifico. A cura del Prof. Paolo Castelnuovo. GlaxoSmithKline SpA; 2011. Multimedial CD.

3. P. Castelnuovo, M. Bignami, P. Battaglia, S. Gallo, A. Karligkiotis, S. Mauri, F. Simoncello, P. Terranova. In: Cosa fare in caso di: Rinoliquorrea. Vol.3 (What to do in case of: CSF-leaks. Vol. 3) - Collana di Aggiornamento Scientifico. A cura del Prof. Paolo Castelnuovo. GlaxoSmithKline SpA; 2011. Multimedial CD.

Presentations ▪ 1) IV Videocorso “Alessandro Guccione”. Chirurgia Micro-Endoscopica Rinosinusale & Basicranio . (Video in concorso). Varese, 6-9 Ottobre, 2004. Video presentation

▪ 2) Neoplasie craniofacciali: trattamento endoscopico VS cranioendoscopico e transfacciale. Varese, 14 Novembre, 2007. Video presentation

▪ 3) IX° Corso di Perfezionamento in Chirurgia Endoscopica Rinosinusale. Clinica Otolaringoiatrica dell’Università dell’Insubria. Varese, 18-20 Gennaio 2010, 1-3 Marzo 2010, 22-24 Marzo 2010, (3-5 Maggio 2010). Clinical cases presentation

▪ 4) Difetti Congeniti del Basicranio: Le Malformazioni della Linea Mediana (Congenital diffects of the skull base: Midline nasal lesions).A. Karligkiotis, S. Gallo, P. Terranova, L. Volpi, F. Sberze, P. Castelnuovo. At: XI Congresso Nazionale SIB - Società Italiana Basicranio (Italian Skull Base Society) - Alla Ricerca di Scelte Terapeutiche Condivise. Verona, 25-27 Novembre, 2010. Oral communication

▪ 5) La Moderna Chirurgia Nasosinusale: Anatomia, Diagnosi e Tecniche Chirurgiche, Corso Avanzato. Clinica Otorinolaringoiatrica dell’Università dell’Insubria. Varese, 13-15 April 2011. Clinical cases presentation

▪ 6) Critical Areas in the Surgical Management of Sinonasal Inverted Papillomas.A. Karligkiotis, S. Gallo, F. Sberze, E. Digilio, P. Terranova, P. Castelnuovo. At the: 1st Congress of the Confederation of the European ORL-HNS and 62 National Congress of the Spanish Society of ORL-HNS. Barcelona, Spain, 2-6 July, 2011. Oral communication

▪ 7) The Modern Sinonasal Surgery: Anatomy, Diagnostics and Operative Techniques, Basic Course. Department of Otorhinolaringology, Università of Insubria. Varese, 03-15 October 2011. Clinical cases presentation

▪ 8) Where do we stand on choanal atresia? A 15-year experience.Karligkiotis A, Gallo S, Zappoli F, Digilio E, Turri-Zanoni M, Padoan G, Meloni F, Castelnuovo P. At the: 5th World Congress for Endoscopic Surgery of the Brain, Skull Base & Spine, combined with The First Global Update on FESS, the Sinuses & the Nose. Vienna, Austria, 29 March - 1 April, 2012. Oral communication

▪ 9) Skull base defects in children: Eleven years experience of pediatric duraplasty. Karligkiotis A, Gallo S, Zocchi J, Bernardini E, Turri-Zanoni M, Pistochini A, Meloni F, Castelnuovo P. At the: 5th World Congress for Endoscopic Surgery of the Brain, Skull Base & Spine, combined with The First Global Update on FESS, the Sinuses & the Nose. Vienna, Austria, 29 March - 1 April, 2012. Oral communication

▪ 10) Surgical approaches to the frontal sinus: Riedel’s Technique. At: Evoluzione del trattamento chirurgico del seno frontale: Dal balloon sinuplasty alla tecnica di Riedel. Milano, 13-14 Dicembre, 2012. Lecture

▪ 11) Oncocytic Schneiderian papilloma: Is it really more aggressive than Inverted papilloma?Karligkiotis A, Gallo S, Volpi L, Turri-Zanoni M, Lepera D, Meloni F, Nicolai P, Castelnuovo P. At: 2nd Meeting of European Academy of ORL-HNS and CE ORL-HNS. Nice, France, 27-30 April, 2013. Poster presentation

Honours and awards 1.Società Italiana di Otorinolaringoiatria e Chirurgia Cervico-Facciale (Italian Society of Otorhinolaryngology – Head and Neck Surgery). Award Best Poster: Winner with the poster:



Granuloma colesterinico dell’apice petroso: nuova “tattica” chirurgica (Cholesterol granuloma of the petrous apex: new surgical “strategy”). P. Terranova, A. Karligkiotis, S. Gallo, F. Basilico, P. Battaglia, M. Bignami, P. Castelnuovo. Granuloma Colesterinico dell’Apice Petroso: Nuova “Tattica” Chirurgica. 97°P. Terranova, A. Karligkiotis, S. Gallo, F. Basilico, P. Battaglia, M. Bignami, P. Castelnuovo. 97° Congresso Nazionale SIO e CCF, Riccione, 19-22 Maggio, 2010.

2.Società Italiana di Otorinolaringoiatria e Chirurgia Cervico-Facciale (Italian Society of Otorhinolaryngology – Head and Neck Surgery). Award Best Poster: Winner with the poster: Ritorno al futuro: La resezione endoscopica delle recidive nasofaringee (Back to the future: The endoscopic resection of nasopharyngeal recurrences). S. Gallo, A. Karligkiotis, M. Turri Zanoni, P. Terranova, L. Volpi, P. Battaglia, M. Bignami, P. Nicolai, P. Castelnuovo. 98° Congresso Nazionale SIO e CCF. Udine, 25-28 Maggio, 2011.. Poster.

Memberships ▪ Junior member of European Rhinologic Society

▪ Founding member of the Italian Academy of Rinology (IAR)

▪ Ordinary member of the Italian ORL Association of Facial Plastic Surgery (AICEFrcf)

▪ Ordinary member of the Italian Society of Otorhinolaryngology – Head and Neck Surgery (SIOchcf)

Conferences Has partecipated from 2004 at 69 national and internationalcongresses and courses:

1) Has partecipated from 2004, at 55 congresses and courses regarding mainly rhinology and endoscopic endonasal and skull base surgery as weel as rhinoplasty, facial plastic, ear and mastoid surgery and head and neck surgery as Delegate.

2) Has partecipated from 2004, at 11 practical dissection courses, regarding endoscopic endonasal and skull base surgery as a Tutor.

3) Has partecipated from 2004, at 3 practical dissection courses, regarding endoscopic endonasal and skull base surgery as Participant.

Delegate in Congresses - Courses - Seminars

▪ I tumori maligni delle ghiandole salivari minori. Novara, 27 Marzo, 2004.

▪ Il ruolo dell’endoscopia nella diagnosi e nel trattamento delle rinosinusiti. Varese, 20-22 Maggio, 2004.

▪ “Chirurgia Endoscopica Rinosinusale”. Le patologie rinosinusali: diagnosi endoscopica, terapia chirurgica. Cassino (FR), 21-22 Gennaio, 2005.

▪ 3rd Biennal International Instructional “Milano Masterclass”. Segment #1 Sinonasal & Skull Base Endoscopic Microsurgery. Milan, 4-6 March, 2005.

▪ 3rd Biennal International Instructional “Milano Masterclass”. Segment #2 Rhinoplasty & Pearls of Facial Plastic Surgery. Milan 6-8 March, 2005.

▪ Il Carcinoma laringeo in stadio iniziale. Trattamento microchirurgico endoscopico mediante laser CO2. Varese, 27 Ottobre, 2005.

▪ Il trattamento micro-endoscopico delle patologie del basicranio. Varese, 18 Novembre, 2005.

▪ Attuali orientamenti in tema di diagnosi e terapia dell’otite media in età pediatrica. Azzate, 10 Dicembre, 2005.

▪ Urgenze ORL per il Pediatra. Varese, 14 Marzo, 2006.

▪ Corso di Aggiornamento Societa Italiana Basicranio. Il Trattamento Ricostruttivo del Basicranio. V Videocorso “Alessandro Guccione”. Varese, 17-18 Marzo, 2006.

▪ Hot Topics in the Management of Head and Neck Cancer. Brescia, 30 November - 2 December, 2006.

▪ 2nd How To Do It. Videocorso. Le vie transfacciali: approccio microendoscopico. Rozzano (MI) 17



Febbraio, 2007.

▪ 4th Biennal International “Milano Masterclass”. Segment #1 Sinonasal & Skull Base Endoscopic Microsurgery. Milan, 23-25 March, 2007.

▪ 4th Biennal International “Milano Masterclass”. Segment #2 Rhinoplasty & Pearls of Facial Plastic Surgery. Milan 25-27 March, 2007.

▪ Diagnosi e Trattamento delle Fistole Rinoliquorali. Varese, 24 Ottobre, 2007.

▪ Live-surgery International Workshop. Aesthetic Reconstruction of Nasal Defects. VI Meeting “Alessandro Guccione”. Varese, 10-12 April, 2008.

▪ 3a Giornata Nazionale di Aggiornamento AICEFrcf. “La Chirurgia Orbito-Palpebrale La Rinoplastica”. Livorno, 29 Novembre, 2008.

▪ 5th Biennal International “Milano Masterclass”. Segment #1 Sinonasal & Skull Base Endoscopic Microsurgery. Milan, 27-29 March, 2009.

▪ 5th Biennal International “Milano Masterclass”. Segment #2 Rhinoplasty. Milan, 29-31 March, 2009.

▪ Prisma – rinosinusite. Aspetti multidisciplinari ed attualità diagnostica e terapeutica. Varese, 3 Aprile, 2009.

▪ International course on Endocrine Surgery - Thyroid Surgery: The Recurrent Laryngeal Nerve. Varese, 26 Giugno, 2009.

▪ Tumori maligni nasosinusali con estensione al basicranio. Diagnostica e opzioni. CRS Amplifon, Milano, 15-16 Ottobre, 2009.

▪ Il trattamento endoscopico microchirurgico delle precancerosi e delle neoplasie laringee mediante laser CO2. Varese, 28 Maggio, 2010.

▪ Viaggio attraverso le vie aeree: Dalla patologia flogistica a quella ostruttiva allergica e non. Gazzada, 29 Maggio, 2010.

▪ 2nd International course on Endocrine Surgery: Graves’ Disease. Varese, 2 July, 2010.

▪ I tumori del rinofaringe: Aggiornamento clinico-diagnostico e terapeutico. CRS Amplifon, Milano, 7-8 Ottobre, 2010.

▪ I° Meeting Scuola Otorinolaringoiatrica di Pavia “Nuove tecnologie in oncologia cervico facciale”. Pavia, 9 Ottobre, 2010.

▪ Seminari di Radiologia Diagnostica e Interventistica 2010 – 2° Ciclo, 3° Seminario: Faringe. Varese, 27 Ottobre, 2010.

▪ Estesioneuroblastoma: aggiornamento clinico-diagnostico e terapeutico. Varese, 9 Novembre, 2010.

▪ Endoscopia e diagnostica per immagini del distretto testa-collo. CRS Amplifon, Milano, 15-16 Novembre, 2010.

▪ Adenocarcinoma intestinale sinonasale (ITAC): Aggiornamento clinico-diagnostico e terapeutico. Varese, 29 Novembre, 2010.

▪ 6th Biennal International “Milano Masterclass”. Segment #1 Endoscopic Sinus & Skull Base Surgery. Milan, 25-27 March, 2011.

▪ 6th Biennal International “Milano Masterclass”. Segment #2 Aesthetic & Reconstructive Rhinoplasty. Milan, 27-29 March, 2011.

▪ Anatomia Dissettoria della Testa in 3D. Sassari, 28-30 Luglio, 2011.

▪ I disturbi del processing uditivo nell’anziano. CRS Amplifon, Milano, 14-15 Novembre, 2011.

▪ La sordità nell’anziano. Varese, 18 Novembre 2011.

▪ Melanoma mucoso naso-sinusale (MM-SN) aggiornamento clinico-diagnositico e terapeutico. Varese, 31 Ottobre, 2011.

▪ Le tracheotomie. Varese, 16 Dicembre, 2011.

▪ Otoplasty and External Ear Reconstruction. Varese, 20 April, 2012.

▪ Nose & Face World Rome 2012. VII International Congress of the International Federation of Facial Plastic Surgery Societies (IFFPSS). Rome, 9-12 May, 2012.

▪ Le urgenze in otologia e vestibologia. Sassari, 9 Giugno, 2012.

▪ Le infezioni ricorrenti delle vie aeree superiori. Alghero, 6 Ottobre, 2012.

▪ Corso Teorico-Pratico AAITO, ADOI, AIPO Sardegna. Percorsi interdiciplinari delle malattie



allergiche per workshop. Specialisti a confronto. Cagliari, 19-20 Ottobre, 2012.

▪ Il paziente con patologie otologiche: percorso diagnostico-terapeutico. Varese, 19 Novembre, 2012.

▪ Le disfonie: inquadramento diagnostico e trattamento. Varese, 23 Novembre, 2012.

▪ 7th Biennal International “Milano Masterclass”. Segment #1 Sinonasal, Orbit & Skull Base Endoscopic Surgery. Milan, 23-24 March, 2013.

▪ 7th Biennal International “Milano Masterclass”. Segment #2 Rhinoplasty – From Minimally Invasive to Structural. Milan, 24-25 March, 2013.

▪ Head and neck anatomy, Sassari, 15-18 Luglio, 2013.

▪ International Course: State of the art in surgery of midline tumors. Milano, 7-9 November, 2013.

▪ I carcinomi indifferenziati del distretto cervico-facciale. Varese, 2 Dicembre, 2013.

▪ Le neoformazioni del cavo orale. Varese, 5 Dicembre, 2013.

▪ XV Convegno Nazionale AOICO. I Tumori della Parotide. Cagliari, 24-25 Gennaio, 2014.

▪ Chirurgia ricostruttiva del distretto testa-collo: esperienza di una scuola. Azienda Ospedaliero-Universitaria di Parma. Parma, 8 Febbraio, 2014.

▪ IV Convegno annuale G.L.O. (Gruppo Lombardo Otorinolaringoiatri). Il G.L.O. per i giovani. Pavia, 27 Marzo, 2014.

▪ IV Convegno annuale G.L.O. (Gruppo Lombardo Otorinolaringoiatri). La chirurgia mininvasiva in Otorinolaringoiatria. Pavia, 28 Marzo, 2014.

Tutor in Dissection Courses

▪ Practical “Full-Immersion” Course on Surgical Anatomy & Operative Techniques of Endoscopic Surgery of the Paranasal Sinuses and Skull Base. Brussels, Belgium 3-6 November, 2004.

▪ Practical “Full-Immersion” Course on Surgical Anatomy & Operative Techniques of Rhinologic Surgery 1.Rhinoplasty, 2.Endoscopic Paranasal Sinus Surgery. Brussels, Belgium 2-5 November, 2005.

▪ Corso Pratico Full-Immersion di Anatomia Dissettiva e Tecniche Operatorie Chirurgia Endoscopica Sinusale e Basicranio, Livello Avanzato. Brussels, Belgium 1-4 November, 2006.

▪ Practical “Full-Immersion” Course on Surgical Anatomy & Operative Techniques in Rhinologic Surgery 1.Rhinoplasty, 2.Endoscopic Paranasal Sinus Surgery. Brussels, Belgium 31 October - 3 November, 2007.

▪ Practical “Full-Immersion” Course on Surgical Anatomy & Operative Techniques in Endoscopic Sinus & Skull Base Surgery. Brussels, Belgium 29 October - 1 November, 2008.

▪ Practical “Full-Immersion” Course on Surgical Anatomy & Operative Techniques in Endoscopic Endonasal Surgery: Paranasal Sinuses – Anterior Skull Base – Nasopharynx. Brussels, Belgium 28-31 October, 2009.

▪ 15th Head and Neck (Workshop) with Cadaveric Dissections. Athens, Greece 19-21 March, 2010.

▪ Practical “Full-Immersion” Course on Surgical Anatomy & Basic Operative Techniques in Rhinologic Surgery 1. Rhinoseptoplasty, 2. Sinonasal Endoscopic Surgery. Brussels, Belgium 3-6 November, 2010.

▪ Practical “Full-Immersion” Course on Core Operative Techniques in Endonasal Endoscopic Surgery 1. Paranasal Sinuses – 2. Skull Base – 3. Nasopharynx. Brussels, Belgium 2-5 November, 2011.

▪ Joint European Diploma of Endoscopic Skull Base Surgery. Segment #1. Paris, France 9-11 Dicembre, 2013.

▪ Joint European Diploma of Endoscopic Skull Base Surgery. Segment #2. Paris, France 10-12 February, 2014.



Participant in Dissection Courses

1. 3-Dimensional Surgical Anatomy of the Nose and Paranasal Sinuses. 2nd Course. Tübingen, Germany 6-8 February, 2012.

2. Transnasal Corridors to Skull Base and Orbit. 3rd Course. Wien, Austria 11-13 April, 2012.

3. Transnasal Corridors to Skull Base and Orbit. 4th Course. Wien, Austria 04-06 June, 2013.

▪

Projects Has performed research activity on Head and Neck anatomy with particular interest on the endoscopic endonasal and skull base perspective and surgical techniques at the following institutes:

▪ Dissection activity at the Laboratory of the Department of Anatomy of the University of Sassari, Italy, in August 2011 for 15 days focusing on the endoscopic endonasal and skull base anatomy and surgical procedures.

▪ Dissection activity at the Laboratory of the Department of Anatomy of the University of Sassari, Italy, in August 2012 for 15 days focusing on the endoscopic endonasal and skull base anatomy and surgical procedures.

▪ Dissection activity at the Dissection room of the Department of Anatomy of the University of Tubingen, Germany in May 2013 for 3 days focusing on the endoscopic endonasal and skull base anatomy and surgical procedures as part of the project: Tubinghen mission, lanched in collaboration between the department of Anatomy of the University of Tubingen, Germany (Chief: Prof. Hirt) and the Department of Otorhinolaryngology of Varese (Chief: Prof. Castelnuovo)

▪ Dissection activity at the Dissection room of the Ecole de Chirurgie du Fer à Moulin of the Assistance Publique – Hopitaux de Paris, France from April 2013 to June 2013 for 30 days focusing on the external and endoscopic nose, sinus and skull base anatomy, ear, mastoid and microscopic lateral skull base anatomy, and salivary glands and neck anatomy including relative surgical procedure as part of the Erasmus Student Placement programme for residents, at the Service ORL (Chief: Prof. Philippe Herman) at Hopital Lariboisière, Paris, France


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