Peptides 2008 : chemistry of peptides in life science ... · Azide as aprotecting groupfor lysine...

Peptides 2008

Chemistry of Peptides in Life Science

Technology and Medicine

Proceedings of

The Thirtieth European Peptide Symposium

Edited byHilkka Lankinen

Jari Vallivirta

Tomas Strandin

Jussi Hepojoki

Proceedings ofthe 30"' European Peptide Symposium Helsinki, Finlandia Hall, 2008

Cyclic opioid peptide antagonists containing (2S)-Mdcp or Dcp in place of Tyrl: 1-01-001 2

Comparison with widely used u and 8 opioid antagonistsSchiller Peter W, Lu Yixin

Solid phase synthesis of alkene dipeptidosulfonamide isosteres using fin cross 1 -01-002 4

metathesis and the incorporation into amyloidogenic amylin(20-29)

Bmuwer Arwin J, Elgerma Ronald C, Jagodzinska Monika, Rijkers Dirk TS, Liskamp Rob MJ

Synthesis of Cyclic Peptide Chitinase Inhibitors: Natural Products with 1 -01 -003 6

Chemotherapeutic Potential

Dixon Mark, Giuntini Francesco, Nathubhai Amit, Andersen Ole, van Aalten Daan,

Eggleston Ian

Dynamic Ligation of peptide electrophiles for the identification of protein-binding 1-01-004 8

fragments and development ofprotein Iigands

Rademann Jorg

Semisynthesis of Membrane-Associated Prion Proteins 1-01-005 10

Olschewski Diana, SeidelRalf, TatzeltJorg, Engelhard Martin, Becker Christian F

From Peptide to Non-Peptide Metalloconstruets: Dynamic Combinatorial Libraries 1-02-007 14

of Oxorhenium Coordinates for the Selection of New Cyclophilin Inhibitors

Clavaud Cecile, Le Gal Julien, Thai Robert, Moutiez Mireille, Dugave Christophe

Solid phase peptide-carbene and peptide-phosphine transition metal catalysts in 1-05-008 16

assymetric synthesis and "green" chemistry

Meldal Morten, Christensen Christian A, Worm-LeonhardKasper, Feldthusen Jensen Jacob,

Benito Juan

Submitted papers: 7

Straightforward Synthesis of Enantiopure Tfm-amino acids from Chiral CF3- 1-01-101 18

Oxazolidines

Brigand Thierry- Huguenot Florent, Chaume Gregory, Caupene Caroline,

Van Severen Marie-Celine

Highly Diastereoselective Synthesis of//2-Amino acids Using Novel Fluorinated 1 -01-102 20

Oxazolidine (Fox) as Chiral Auxiliary

Brigaud Thierry, Pytkowicz Julien, Tessier Arnaud, Lahmar Now

Synthesis of CF3-Pseudoproline Units: An approach to conformational^ constrained 1 -01 -103 22

dipeptides

Chaume Gregory, Barbeau Olivier, Brigaud Thierry

Synthesis of antimicrobial peptide Parasin I 1 -01-104 24

KrasnoschekAnastasia A, Gluzdikov Ivan A, Vinogradov Valentin A, Titov Mikhail I

Synthesis of biological active cyclopeptides corresponding to 4th loop of nerve growth 1 -01-105 26

factor

Gudasheva Tatiana, Morozova Anna, Antipova Tatiana, Akparov Valery, Seredenin Sergey

Enantioselective synthesis of fluorinatedp-borono-L-phenylalanines enriched with 10B 1-01-106 28

atom

Hattori Yoshihide, Kurihara Kei, Asano Tomoyuki, Kirihata Mitsunori, Yamaguchi Yoshihiro,

Wakamiya Taleaki

XXIV

Synthetic chemistry

New APA inhibitors interacting with the SI subsite bring new insights in the APA 1 -01 -107 30

substrate specificity mediated by the calcium ion

Claperon Cedric, Rozenfeld Raphe!, Iturrioz Xavier, Okada Mayumi, Roques Bernard,

Maigret Bernard, LLorens Cortes Catherine, Inguimhert Nicolas

Development of water-soluble click peptides by use of the 0-acyl isopeptide method: 1-01-108 32

In situ production ofAlzheimer's amyloid B peptideTanJguchiAtsuhiko, Sohma Youhei, Skwarczynski Mariwz, Nagano Takami, Okada Takuma,

Ikeda Keisuke, Prakash Halan, Mukai Hidehito, Hayashi Yoshio, Kimura Tooru, Hirota Shun,

Matsuzaki Katsumi, Kiso Yoshiaki

Sulfur-containing amino acid amides of phenolic acids 1-01-109 34

Spasova Maya, Paizs Csaba, Stoykova Boyka, Milkova Tsenka, Irimie Florin

1,3-Disubstituted l,2,3,4-tetrahydro-/?-carbolines as peptidomimetics of tryptophan: 1-01-110 36

synthesis and conformational analysis

Shtpska Marta, Misiak Maria, Urhanczyk-Lipkowska Zofia, Kozminski Wiktor,

Misicka Aleksandra

Photoinduced macrocyclizations on helical Bpa/Met oligopeptides 1-01-111 38

Moretto Alessandro, Crisma Marco, Formaggio Fernando, Huck LawrenceA,

Mangion Dino, Leigh William J, Toniolo Claudio

Peptido[2]rotaxanes with amino acids containing either functional groups or folded 1-01-112 40

peptide segments in the axle

Moretto Alessandro, Crisma Marco, Toniolo Claudio

Synthesis ofpeptides containing five-member cyclic /V-ainidino-amino acids 1-01-113 42

Moskalenko Yulia, Panarin Eugeniy, Leko Maria, Shkarubskaya Zoya, Dorosh Marina,

Bmvv Sergey

Hydrolytic action of Candida antarctica lipase B (CAL-B) and pig liver esterase (PLE) 1-01-114 44

upon various carboxyl protecting groups

Thodi Kalliopi, Barbayianni Efrosini, Fotakopoulou Irene, Bornscheuer Uwe T,

Constantinou-Kokolou Violetta, Kokotos George, Moutevelis-Minakakis Panagiota

Synthesis of C-terminal exenatide sequence H-Ala-Pro-Pro-Pro-Ser-NH2 1-01-115 46

Nikolskaia Sofia, NurutdinovAlexandr, Glazdikov Ivan A, Vinogradov Valentin A, Titov

Mikhail I

Conjugation of glaucine to hydroxycinnamoyl amino acid amides 1-01-116 48

Spasova Maya, Philipov Stephan, Avramov Georgi, Milkova Tsenka

Synthesis and Biological Activity of Cinnamic Acid Amides of Oxazolc Containing 1-01-117 50

Amino Acids

Stankova Ivanka, Spasova Maya, Shishkov Sloyan

Synthesis of novel hydantoin-phosphonic acids and dipeptides consist hydantoin 1-01-118 52

structure with potential biological activityTodorov Petar, Naydenova Emilia, Pavlov Nikola, Troev Kolio

Synthesis resolution and absolute configuration ofBpAib a benzophenone-containing 1-01-119 54

<?'-tetrasubsti(tited a-amino acid

Wright Karen, Wakselman Michel, Mazaleyrat Jean-Paul, MorettoAlessandro,

Crisma Marco, Formaggio Fernando, Toniolo Claudio

Synthesis and conformational analysis of doubly spin-labelled ^-peptides based on the 1-01-120 56

nitroxide bearing POAC residue

Toniolo Claudio, Formaggio Fernando, Toffoletti Antonio, Franco Lorenzo,

Mazaleyrat Jean-Paul, Wakselman Michel, Wright Karen

/V-Methylation ofjV"-acetylated C°-ethylated fully-extended homo-peptides: 1-01-121 58

synthetic and conformational aspectsMoretto Alessandro, Crisma Marco, Formaggio Fernando, Toniolo Claudio

XXV


A substituted proline with a strong preference for the helix conformation: 1-01-122 60

an X-ray diffraction investigationMoret/o Alessandro, Toniolo Clavdio, Crisma Marco, Formaggio Fernando,

Kaplein Bernard, Broxterman Quirimis B

Impact of ionic liquids on peptide acylation reactions 1-01-123 62

Wespe Christian, Mrestani-Klaus Carmen, Bordasa Frank

Synthesis of a novel a«-disubstituted glycine a-cyclobutylalaiiine 1-01-124 64

Yamada Takashi, Okumura Tomoko, Mizukoshi Rina, Murashima Takashi,

Miyazawa Toshifumi, In Yasuko

Photosvvitchsible bisintercalators - synthesis of Triostin A analogs 1-01-125 66

ZobelAnsgar, Gaits Katharina, Wollschltiger Katrin, NiefiAnke, Juodaityle Jovita,

Sewald Norhert

Design and synthesis of a non - peptide PAR-1 thrombin receptor antagonist using 1 -01 -126 68

cyclohexane as template

Androutsou Maria-Eleni, Agelis George, Magoulas George, Keppa Pasxalina,

Saifeddine Mahmound, Hollenberg Morley, Matsoukas John M

Synthesis and Activity ofCyclic Analogues of PTH(l-ll) 1-01-128 72

Caporale Andrea, Zanta Fabrizio, Cabrele Chiara, Wittelsberger Angela, Peggion Evaristo.

An Efficient Method for the Synthesis of C-Terminal Amidated Enkephalins 1 -01 -129 74

Arabanian Armin, Balalaie Saeed, MohammadnejadMahdieh, Gross Jiirgen H

Synthesis of Novel Gn-RH Analogues Using Ugi-4MCR 1-01-130 76

Balalaie Saeed, Arabanian Armin, MohammadnejadMahdieh, Gross Jiirgen H

Resin Comparison and Fast Conventional Synthesis of Human SDF-la on the 1-01-131 78

Symphony® Tribute and Prelude

PatelHirendra, Chantell Christina, Fuentes German, Menaknru Mahendra

Isopeptide method: an efficient preparation of difficult peptides on solid support 1-01-132 80

Yoshiya Takii, Taniguchi Atsuhiko, AbeNaoko, ItoNui, Sohma Youhei,

Skwarczynski Mariusz, Kimura Tooru, Hayashi Yoshio, Kiso Yoshiaki

The application ofN-(46-dimethoxy-135-triazin-2-yl)strychninium tetrafluorohorate in 1-01-133 82

SPPS as traceless enantioselective coupling reagentsKaminski Zbigniew J, Kolesinska Beata

Synthesis of peptides from racemic amino acids with predictable optical purity and 1-01-134 84

configuration of the product by using traceless chiral triazine coupling reagentsKolesinska Beata, Kasperowicz Katarzyna, Kaminski Zbigniew J

2-Chloro-4,6-Ws-(222-trifluoroethoxy)-l,3,5-triazine and JV-[4,6-(2,2,2-trifluoroethoxy)- 1-01-135 86

l,3,5-triazin-2-yl)]-jV-methylmorpholinium tetrafluorohorate as coupling reagentsJastrzabekKonrad, Kolesinska Beata, Kaminski Zbigniew J

Solid-Phase Synthesis of the Cys-Rich Peptide Linaclotide 1 -01-136 88

Albericio Fernando, GiraudMatthieu, Gongora-Benitez Miriam, Paradis-Bas Marta,

Tulla-Puche Judit, Werbitzky Oleg

Multiple, successive azide-alkyne cycloadditions as a new ligation tool 1-05-180 90

Valverde Ibai E, Aucagne Vincent, Delmas Agnes F

Instability of tert-butyl esters towards hydrazinolysis. Side chain hydrazide formation 1-01-138 92

in peptides

Kruszynski Marian, Schmidt Albert, Heavner George A, Pomeranlz Steven

CLEAR-OX: Synthesis of Disulfide-Bridged Peptides Under Mild Conditions 1-01-139 94

DarlakKrzysztof, Cecil MatthewR, Czerwinski Andrzej, DarlakMiroslawa, LongDeAnna W,McGrew Danny, Morgan TimothyL, Valenzuela Francisco, Barany George

XXVI

Synthetic chemistry

Solid-phase synthesis of 5-arylhistidines via a microwave-assisted Suzuki-Miyaura 1-01-140 96

cross-couplingCereza Vanessa, Verdie Pascal, Amblard Muriel, Martinez.Jean, Planas Maria, Feliu Lidia

Novel peptide-hetorocycle conjugates: derivatives of 3-(benzimidazol-5-yl)alanine 1-01-141 98

Ratajska Malgorzata, Khtczyk Alicja, Cebrat Marek, Stefanowicz Piotr, Bartosz-Bechowski

Hubert, Szewczuk Zbigniew

Inhibitors ofDapE and ArgE enzymes as new antimicrobial agents: Synthesis and 1-01-142 100

characterization

Hlavacek Jan, PichaJan, Vanek Vaclav, JirdcekJiri, Slaninovd Jifina, Fucik Vladimir,

Gilner Danuta, Holz Richard C

Self-assembling Antimicrobial Cyclic Pseudopeptides including Aza-//3-Amino Acids 1-01-143 102

Laurencin Mathieu, Legrand Baptiste, Mouret Liza, Zatyhiy-Gaudin Celine, Henry Joel,

Bondon Arnaud, Fleury Yannick, Baudy-Floc 'h Michele

Controlling a-helical secondary structure of oligopeptides and its use as a chiral 1-01 -144 104

catalyst

Tanaka Masakazu, Nagano Masanobu, Demizit Yosake, Doi Mitsunobu, Kurihara Masaaki,

Suemune Hiroshi

Helical-screw handedness of peptides composed of diastereomeric cyclic amino acids 1-01-145 106

Nagano Masanohn, Tanaka Masakazu, Doi Mitsunobu, Kurihara Masaaki, Suemune Hiroshi

Multi-tethered and orthogonally protected piperazine diazepane and pyrrolidone 1 -01 -146 108

building blocks for fast "around-the-scaffold" drug designGellerman Gary, Hazan Eran, Kovaliov Marina, Albeck Amnon, Shatzmiler Shimon

The studies on the solid phase synthesis and selective detection of peptide-derived 1-01-147 110

Amadori products by mass spectrometry

Kapczynska Katarzyna, Stefanowicz Piotr, Kijewska Monika, Pasikowski Pawel,

Szewczuk Zbigniew

Synthesis modeling studies and biological activities of a non-peptide ATI receptor 1-01-148 112

angiotensin II

Agelis George, Ma/soukas Minos-Timotheos, Resvani Amalia, Kelaidonis Konstantinos,

Keppa Pasxalina, Tselios Theodore, Vlahakos Demetrios, Matsoukas JohnM

Synthesis of human and rat obestatin 1-01-149 114

Seylablaeva Sevil, Titov Mikhail I

Versatile methods for synthesizing acyl-tetramic acids peptide analogs 1 -02-150 116

Davidov Gali, Mozes Tamar, Khandadash Raz, Diestel Randi, Sasse Florenz, Byk Gerardo

Mild and Selective Boc Deprotection on Acid Cleavable Rink-Amide MBHA Resin 1 -03-151 118

Freeman Noam S, Gilon Chaim

A potent and non-explosive subslituent for classical benzotriazole-based additives: 1-03-152 120

Oxyma Pure

Subiros-Funosas Ramon, Ei-Faham Ayman, Albericio Fernando

Site-specific PEGylation of human IgGI-Fab using a rationally designed trypsin 1-03-153 122

variant

Liebscher Sandra, Trost Eva, Hoess Eva, Bordusa Frank

Resin Comparison and Fast Conventional Synthesis of Human SDF-la on the 1 -03-154 124

Symphony)® Tribute and Prelude

Patel Hirendra, Chantell Christina, Fuentes German, Menakuru Mahendra

Fast Fmoc-deprotection reagent for peptide synthesis 1-03-155 126

Rawer Siephan, Vidal-Wagner Juan, Henklein Peter

XXVII


A Non-Explosive Replacement for Benzotriazole-based Coupling Reagents 1-03-156 128

El-Faham Ayman, Siihirds-Funosas Ramon, Albericio Fernando

Efficient Chemical Synthesis ofAmides and Peptides using Phosphonic Acid/Alkylene 1-03-157 130

Oxide Chemistry

Bayryamov Stanislav, Danalev Dantcho, Vassilev Nikolay

Solid Phase Synthesis of Aza-Peptides Using Activated A^-Substituted Ddz Protected 1-03-158 132

HydrazinesFreeman Noam S, Hnrevich Matlan, Gilon Chaim

Improved synthesis of relaxin-2 1-03-159 134

Barlos Kostas, Vasileiou Zoe, Gatos Dimilrios, Bartos Kleomenis

Synthesis of peptides from racemic amino acids with predictable optical purity and 1-03-160 136

configuration ofthe product by using traceless chiral triazine coupling reagents

Kolesinska, Beata

Backbone cyclization of peptides via 7V-functionalized phosphorylated tyrosine 1-03-161 138

Reissmann Siegmund, Zoda MohammadSafa

Studies on the synthesis of the kazal-type inhibitor LEKTI domain 6 1 -03-162 140

Vasileiou Zoe, Barlos Kostas, Gatos Dimitrios, Adermann Kmtt, Forssmann Wolf-Georg,Barlos Kleomenis

Azide as a protecting group for lysine side chains on the solid phase peptide synthesis 1-03-163 142

oriented toward the peptide condensation by the thioester method

Katayama Hidekazu, Hojo Hironobu, Ohira Tsuyoshi, Nakahara Yoshiaki

Peptide thioester preparation and peptide ligation using cysteinyl prolyl ester (CPE) 1 -03-164 144

autoactivating unit

Kawakami Tom, Aimoto Saburo

Synthesis of cysteine-rich peptides 1-03-165 146

Kdddr Kinga, Panyi Gydrgy, Varga Zollctn, Toth Gdbor K

Glycopeptides - a synthetic challenge 1-03-166 148

Toth Gdbor K, Kdddr Kinga, Hegyi Orsolya, Csikos Orsolya, Kalmdr Ldszlo,

Kerekgydrto Jdnos

Peptide synthesis in water using Boc-amino acid nanoparticles 1 -03-167 150

Hojo Keiko, Ichikawa Hideki, Fukumori Yoshinobu, Kawasaki Koichi

Solid-phase synthesis of 4,5,8-trihydroxy-9,10-anthraquinone-l-yl-(tuftsin and retro- 1-03-168 152

tuftsin) derivatives

Kukowska-Kaszuba Magdalena, Dzierzbicka Krysiyna, Mackiewicz Zbigniew

Solid phase synthesis of tuftsin derivatives conjugated to 1,4-dihydroxyanthraquinone 1-03-169 154

Kukowska-Kaszuba Magdalena, Dzierzbicka Kiystyna, Mackiewicz Zbigniew

Microwave-assisted solid-phase peptide synthesis: shifting off the limitations affecting 1-04-170 156

conventional synthetic strategiesRizzolo Fabio, Sabalino Giuseppina, Fridkin Mati, Chelli Mario, Rovero Paolo,PapiniAnna Maria

Solid-phase peptide synthesis at elevated temperatures - A comparison of conventional 1-04-171 158

and microwave heating technologyBacsa Bernadett, Horvdti Kata, Bosze Szilvia, Andreae Fritz, Kappe C Oliver

Microwave mediated peptide synthesis in comparison to conventional peptide synthesis 1-04-172 160

Henklein Peter, Roder Rene, Rapp Wolfgang

Enhanced microwave assisted on-bead disulfide bond formation method: Synthesis of 1-04-173 162a-Conotoxin Mil

Galanis Athanassios S, Albericio Fernando, Grotli Morten

XXVIII

Synthetic chemistry

Solid phase peptide synthesis in aqueous environment using microwave assistance 1-04-174 164

heatingGalanisAthanassios S, Albericio Fernando, Grotli Morten

Synthetic antifreeze glycopeptide analogues: synthesis structural and functional studies 1-04-175 166

Heggemann Carotin, Budke Carsten, Thomas Koop, Sewald Norbert

LC-ESI-MS Characterization and Prep-RP-HPLC purification of FMDV Synthetic 1-04-176 168

Viral PeptidesOzdemir Zafer Omer, Topuzogullari Mural, Karabulut Erdem, Mustafaeva Zeynep

Insights into /^-microglobulin amyloidogenesis using site-directed-isotope labelling 1-05-177 170

Fourier transformed infrared spectroscopy and native chemical ligationBriandBenoit, Beyermann Michael, Fabian Heinz

Thiocarbamate-Iinked peptides by chemoselective peptide ligation 1 -05-178 172

Besret Soizic, Ollivier Nathalie, Blanpain Annick, Melnyk Oleg

Synthesis of azapeptides by chemical ligation 1-05-179 174

Ollivier Nathalie, Besret Soizic, Blanpain Annick, Melnyk Oleg

Synthesis of peptide thioester by Fmoc chemistry through hydroxyl side chain 1-05-181 176

anchoringLelievre Dominique, Barta Pavel, Aucagne Vincent, DelmasAgnes F

Oxidative folding of conopeptides in an ionic liquid 1-07-182 178

Miloslavina Alesia, Stark Annegret, Leipold Enrico, Heinemann Stefan H, ImhofDiana

Exogenous delivery and molecular evolution: peptides based on C*-methylated a-amino 1-08-183 180

acid as asymmetric catalysts in the syntheses of simple sugars

Morelto Alessandro, Formaggio Fernando, Toniolo Claudia, Broxterman QuirinusB,WeberArthur L, Pizzarello Sandra

The application ofN-Alkyl cysteine (NAC)-assisted thioesterification reaction to the 1-09-184 182

synthesis ofpolypeptides by the thioester method

Hojo Hironobu, Ozawa Chinatsu, Kaiayama Hidekazu, Nakahara Yuko, Nakahara Yoshiaki

Construction of 0-glycoside peptide libraries by Fmoc-SPPS using the building block 1-09-185 184

strategyKawasaki Takayasu, Miyajima Midori, Kawahira Noboru, Hirata Akiyoshi,Ohyama Takafumi, Nokihara Kiyoshi

Micrawave-assisted synthesis and characterization of biodegradable poly(l-Azabi- 1-13-186 186

cyclo[4.2.0)octane) as a potential carrier system for antigenic peptide and proteinsKarabulut Erdem, Ozdemir Zafer Omer, Saricay Yunus, Mustafaeva Zeynep

New Building Blocks Useful For The Synthesis Of Ribosylated Peptides 1-15-188 188

Bonache MAngeles, Nuti Francesco, Le Chevalier lsaadAlexandra, Peroni Elisa,

Chelli Mario, Papini Anna Maria

Parallel small scale peptide synthesis meets a fast low-cost purification method for the 1 -16-189 190

production of high quality peptide microarrays to analyze DNA-protein interactions

Dauber Marc, Schnoelzer Martina, HoheiselJoerg, Jacob Anette

Synthesis of desmycosin analogs containing peptides at 4'-position 1 -20-190 192

Karpenko Victoria, Sumbatyan Natalia, Korshunova Galina, Bogdanov Alexey

Submitted papers: 87

XXIX

Proceedings ofthe 3(1"' European Peptide Symposium Helsinki, FMandia Hall, 2008

Non Peptide Mimetics: A New Generation of Drugs

Matsoukas John M, Agelis George, Androulsou Maria-Eleni, Kalavrizioti Dimitra,

Kelaidonis Konslcmtinos, Keppa Pasxalina, Magoulas George,

Matsoukas Minos-Timotheos, Resvani Amalia

Chemotactic Drug Targeting (CDT) 2-05-002 196

Synthesis and in vitro application of chemotactic drug delivery systems

Bai Katalin Boglarka, Lang Orsolya, Szabo Ildiko, Kiihidai Ldszlo, Hitdecz Ferenc,

Mezb Gdbor

Solid-Phase synthesis ofpyrrolo[3,2-£] [ 1,4]diazepin-2-ones peptide turn mimics 2-05-003 198

Deaudelin Philippe, Lubell William D

Synthesis of a Series of Cyclic i-to-i+4 Side Chain-to-Side Chain 1,4-Disubstituted 2-07-004 200

[1,2,3] triazolyl-Bridged PTHrP(ll-19) Derivatives

Le Chevalier IsaadAlexandra, Scrima Mario, Cantel Sonia, Levy Jay, Rovero Paolo,

D'Ursi Anna Maria, Chorev Michael, PapiniAnna Maria

Modulating Biology with Cryptic Cell Penetrating Peptides 2-07-005 202

Howl John, Jones Sarah

Manipulation and measurement of intracellular calpain activity by new cell 2-17-006 204

penetrating peptide conjugate

Bdnoczi Zoltan, Farkas Attila, Alexa Anita, Tantos Agnes, Tompa Peter, Friedrich Peter,

Hudecz Ferenc

Modification of the chemical structure of cell-penetrating peptides: 2-17-007 206

impact on cargo deliveryAvssedai Baptiste, Dupont Edmond, Sagan Sandrine, Joliot Alain, Lavielle Solange,

Chassaing Gerard, Bitrlina Fahienne

Surface-bound cationic antimicrobial peptides: The effect of immobilization upon the 2-19-008 208

activity spectrum and the mode of action

Bagheri Mojtaba, Beyermann Michael, Dathe Margitla

Design and synthesis of cell-penetrating nucleopeptides 2-19-009 210

Geotti-Bianchini Piero, Beyrath Julien, Chaloin Olivier, Formaggio Fernando,

Bianco Alberto

Human cystatin C interactions with amyloidogenic molecules 2-19-010 212

Juszczyk Paulina, Szymanska Aneta, Rodziewicz-Motowidio Syhvia, Jankowska Elzbieta,

Ladewska Anna, Spodzieja Maria, Kolodziejczyk Aleksandra S, Paraschiv Gabriela,

Przybylski Michael, Grzonka Zbigniew

Mimetibodies A New Platform Technology for the Development of Biologically 2-23-011 214

Active Peptides that Prolongs the Half-Life

Heavner GeorgeA

A novel nucleolar localization signal sequence derived by structural minimization of 2-25-012 216

an animal toxin

Rddis-Baptista Gandhi, de la Torre Beatriz G, Andreu David

N-acylation of anti-LPS peptides renders micellar and tubular nanostructures with 2-29-013 218

enhanced LPS-neutralizing activityMas-Moruno Carlos, Cascales Laura, Cruz Luis J., Mora Puig, Perez-Paya Enrique,Albericio Fernando


XXX

Bioactive peptides

New Amide Analogues OfAntistasin Isoform 2 And 3 2-01-101 220

Danalev Dcmtcho, Vezenkov Lyubomir

Synthesis of the SI29-1229 fragment of the extracellular domain of the VEGF receptor 2-01-102 222

1 embedding the ligand binding site

Goncalves Victor, Gantier Benoit, Huguenot Florent, Leproux Pascale, Garbay Christiane,

Vidal Michel, lnguimbert Nicolas

In-vivo and in-vitro activities of new L-Valine derivatives: structure-activity 2-01 -103 224

relationshipsTsekova Daniela, Tancheva Lyubka, Makakova Emilia, Alov Petko, Pajeva Ilza,

Petkov Vesselin

N-Methylation of cyclic enkephalin analogues 2-01-104 226

Berezowska Irena, Weltrowska Grazyna, Wilkes Brian C, Lemieux Carole, Chung Nga N,

Schiller Peter W

A useful scaffold for^-turn scan in peptides. Enkephalin and morphiceptin analogues 2-01-105 228

containing a 4-aminopyroglutamic acid residue

Kaczmarek Krzysztof, Chung Nga N, Schiller Peter W

Modifications of the Myelin Basic Protein epitope MBP87-99 divert Th2 to Thl: 2-01 -106 230

Immune responses in peripheral blood mononuclear cells (PBMC) from MultipleSclerosis patientsDeraos George, Chatzanloni Kokona, Matsoukas Minos-Timotheos, Katsara Maria,

Tselios Theodore, Deraos Spyros, Papathanasopoulos Panagiotis, Vynios Dimitrios,

Apo.tolopoulos Vasso, Mouzaki Athanasia, Matsoukas John M

Solid-Phase Synthesis and Effects of Amino Acid and Peptide Analogs of Non-Protein 2-01-107 232

Amino Acid Canavanine on NociceptionDzimbova Tatiana, Djambazova Elena, Bocheva Adriana, Pajpanova Tamara,

GolovinskyEvgeny

Synthesis of/?2-amino acids and their application in endomorphin analogues 2-01-108 234

Tymecka Dagmara, Kosson Piotr, Lipkowski Andrzej W, Misicka Aleksandra

Non-Protein Amino Acid Analogues of Melanocyte Inhibiting Factor (MIF-1): 2-01-109 236

Synthesis and Effects of NociceptionKalauzka Rositsa, Dzimbova Tatiana, Djambazova Elena, BochevaAdriana,

Pajpanova Tamara

Design And Synthesis Of New Peptide Mimetics With Potential /?-secretase Inhibition 2-01-110 238

ActivityIvanov Ivan, Danalev Dantcho, Vezenkov Lyubomir

Oostatic peptides containing D-amino acids: Activity and degradation in the flesh fly 2-01-111 240

Neobellieria bullata

Bennetovd Blanka, Slaninovd Jifina, Cerny Bohuslav, Vlasdkovd Vera, Hollk Josef,

Tykva Richard, Hlavdcek Jan

Incorporation ofAza-/?3-Amino Acid into 26RFa(20 the Endogenous Ligand of 2-01-112 242

GPR103 : Structural AnalysisTasseau Olivier, Legrand Baptiste, Bondon Arnaud, Leprince Jerome, Validly Hubert,Baudy-Floc 'h Michele

An investigation of the functional requirements ofApidaecin Ib C-terminal fragment 2-01-113 244

by means of peptoid-peptide hybridsGobbo Marina, Benincasa Monica, Bolognini Erika, Rossi Valentino, Rocchi Raniero,

Gennaro Renato

XXXI


Pipecolic Acid Disrupts Collagen Triple Helix Structure in Model Peptides 2-01-114 246

Shankar Sonu Ram, Islam Md'Nuruh Tanaka Yuji, Kato Tamaki. Nish'mo Norikazu

Analgesic Effects of MIF-l's Analogues 2-01-115 248

Bocheva Adriana, Kalauzka Rosilsa, Pajpanova Tamara

Synthesis and antiproliferative activity against breast and colon cancer cells of 2-01-116 250

peptidomimetics based on Substance P C-terminal region hexapeptideGlezakos Peims, Stahtea Xanthi, Sarigiannis Yiarmis, Karamanos Nikos,

Stavropoulos George

Macrocyclic phosphino dipeptide isostere inhibitors of/3 secretase (BACE1) with 2-01-117 252

improved serum stability

Manzenrieder Florian, Huber Timo, KuttraffChristian, Dorner-Ciossek Cornelia,

Kessler Horst

Design and synthesis of cyclotheonamide analogs with a basic P3 residue as inhibitors 2-01-118 254

ofhuman /Mxyptase

Schaschke Norbert, SommerhoffChristian P

The potent antiproliferative activity of small hydrophobic peptides containing 2-01-119 256

adamantyl group

Miyazaki Anna, Tsuda Yuko, Miyawaki Youhei, Fukushima Shaji, Yokoi Toshto,

Vdnlns Tibot; Bokonyi Gyorg)'i, Szabo Edit, Horvdlh Aniko, Keri Gyorgy, Okada Yoshio

Antimicrobial peptides tailored for plant protection 2-02-120 258

Ferre Rafael, Monroe Sylvie, Badosa Esther, Cabrefiga Jordi, Besah't Emili, Feliu Lidia,

Moniesinos Emilio, Bardaji Eduard, Planas Maria

Selection of chromogenic and fluorogenic substrates of neutrophil serine proteases 2-02-121 260

using combinatorial chemistry approachLesnerAdam, Wysocka Magdalena, Gitzow Ka/arqwi, Wiczk Wiselaw, Rolka Krzysztof

Selection of peptomeric inhibitors of bovine a-chymotrypsin and cathepsin G based 2-02-122 262

on trypsin inhibitor SFTI-1 using combinatorial chemistry approachDebowski Dawid, Lqgowska Anna, Wysocka Magdalena, LesnerAdam, Rolka Krzysztof

Using a random peptide library to screen for antimicrobial activity against 2-02-123 264

Pseudomonas aeruginosaMikut Ralf, Hilperl Kai

Conformational Preferences of Cyclopeptides Formed by i-to-i+4 Side Chain-to-Side 2-03-124 266

Chain Cyclization via 1,4-Disubstituted (l,2,3]Triazolyl MoietyScrima Mario, Le Chevaleir IsaadAlexandra, Grimaldi Manuela, Rovero Paolo, PapiniAnna Maria, Chorev Michael, D 'UrsiAnna Maria

Solid-phase synthesis and biological activity of linear tuftsin and retro-tuftsin 2-03-125 268

derivatives

Kukowska-Kaszuba Magdalena, Dzierzbicka Krystyna, Mackiewicz Zbigniew

Biocatalyst-Catalyzed Peptide Synthesis Using Inverse Substrates as Acyl Donorl2 2-03-126 270

Sekizaki Haruo, Fuchise Tomoyoshi, Kojoma Mareshige, Toyota Eiko

Synthesis of Conjugates of MDP and nor-MDP linked to Tuftsin Derivatives as 2-03-127 272

Potential Immunomodulators

Dzierzbicka Krystyna, Wardowska Anna, Kukowska-Kaszuba Magdalena, MysliwskiAndrzej

On-resin microwaves -assisted ring closing metathesis for rapid synthesis of 2-04-128 274

Octreotide dicarba-anatoguesDi CianniAlessandra, D 'Addona Debora, Rizzolo Fabio, Papini Anna Maria,Ginanneschi Maitro

XXXII

Bioactive peptides

Efficient microwave-assisted synthesis of myelin epitopes MOG 35-55 and 2-04-129 276

MOG 97-108 using CLTR-C1 resin

Fri/igou Irene, Androutsou Maria-Eleni, Agelis George, Malsoukas John M,

Tselios Theodore

Microwave-Assisted Solid Phase Synthesis of Backbone Cyclic Glycopeptide Libraries 2-04-130 278

Nuti Francesco, Qvit Nir, Rizzolo Fabio, Harevich Mattan, Peroni Elisa, Rovero Paolo,

GUon Chaim, PapiniAnna Maria

Synthesis and folding ofthe circular cystine knotted cyclotide cycloviolacin 02 2-05-13 1 280

Leta Aboye Teshome, ClarkRichard J, Craik David J, Goransson Ulf

Modification of the regenerative chemokine SDF1 a to allow fluorescence imaging 2-05-132 282

Bellmann-Sickerl Kathrin, Baumann Lars, Beck-Sickinger Annette G

P5U and urantide modified at position 7 with Tpi 2-07-133 284

Auriemma Luigia, Campiglia Pietro, Gomez-Monterrey Isabel Maria, Novellino Eilore,

Sorrentino Raffaella, Carotenuto Alfonso, Grieco Paolo

Novel antimicrobial peptides from the venom of solitary bees 2-07-135 286

Cefovsky Vaclav, Hovorka Oldfich, Cvaeka Josef, Voburka Zdenik, Slaninova Jifina, Fucik

Vladimir, Borovickovd Lenka, Bedndrovd Lucie, Budisinsky Milos

Antimicrobial activity of analogues of the peptide isolated from the venom ofsocial 2-07-136 288

wasp Polistes major major inhabiting the Dominican RepublicJezek Rudolf, Sebestik Jaroslav, Safarik Martin, Fucik Vladimir, Borovickovd Lenka,

Cefovsky Vaclav, Slaninova Jifina

Antimicrobial properties of new mastoparan analogues 2-07-137 290

Ruczynski Jaroslaw, Parfianowicz Brygida, Olkowicz Mariola, Mucha Piotr, SkupienMagdalena, Rekowski Piotr, Wisniewska Katarzyna, Dabrowska-Szponar Maria

Influence of bulky 3,3-diphenylalanine isomers at position 2 ofAVP analogues on their 2-07-138 292

conformation

Kwiatkowska Anna, Sikorska Emilia

/V-terminal modification of arginine vasopressin with C/S,-l-amino-4-phenyl- 2-07-139 294

cyclohexane carboxylic acid: Highly potent oxytocin receptor antagonistsPrahl Adam, Kwiatkowska Anna, Sleszynska Malgorzala, Derdowska Izabela, Sobolewski

Dariusz, Borovickovd Lenka, Slaninova Jirina, Lammek Bernard

Influence of (2S,4R)-4-(2-naphthylmethyl)-pyrrolidine-2-carboxylic acid in position 2 2-07-140 296

of arginine vasopressin and its analogues on pharmacological propertiesDerdowska Izabela, Kwiatkowska Anna, PrahlAdam, Sobolewski Dariusz, Borovickovd

Lenka, Slaninova Jifina, Lammek Bernard

New analogs of the antimicrobial Gramicidin S 2-07-141 298

Ciarkowski Jerzy, Mickiewicz Beata, Kamysz Elzbieta, Kamysz Wojciech, Rodziewicz-

Motowidlo Sylwia

Analogues of arginine vasopressin modified in the N-terminal part ofthe molecule 2-07-142 300

with a-2-indanylglycine. Highly active and selective antiuterotonic agentsLammek Bernard, Kwiatkowska Anna, Derdowska Izabela, PrahlAdam,

Sobolewski Dariusz, Sleszynska Malgorzata, Borovickovd Lenka, Slaninova Jifina

Cyclic enkephalin analogs containing two alkylurea units 2-07-143 302

Luczak Sylwia, Ciarkowski Jerzy, Rodziewicz-Motowideo Sylwia, Czaplewski Cezary,WojcikJacek, Nowakowski Michal, Kwasiborska Maria, Izdebski Jan, OleszczukMarta,

Schiller Peter W, Chung NN

Analogues of bradykinin B2 receptor antagonist 2-07-144 304

Sobolewski Dariusz, Neugebauer Witold, C6te Jerome, Belanger Simon,

Gobeil FernandJr, LammekBernard, Prahl Adam

XXXIII

Proceedings ofthe 3ff'' European Peptide Symposium Helsinki, Finlandia Hall, 2008

Metal ion interactions within the 1-16 N-terminal region of/^-Amyloid 2-07-145 306

Damante ChiaraAntonia, OszKatalin, Nag)> Zoltdn, Pappalardo Giuseppe,Grasso Ghdia, Impellizzeri Giuseppe, Rizzarelli Enrico, Sovdgo Imre

Antibacterial activity and resistance to proteolytic degradation of trichogin GAIV 2-07-146 308

and selected analoguesToniolo Claudio, De Zotti Maria, Formaggio Fernando, Stella Lorenzo, Kim Mi-Hyun,

Park Yoonkyung, Hahm Kyung-Soo

The chiral sequence of a natural peptide inhibitor of HIV-1 integrase elucidated 2-07-147 310

De Zotti Maria, Toniolo Claudio, Formaggio Fernando, Kaplein Bernard,

Broxterman Quirimis B, Felock Peter J, Hazuda Daria J, Singh Sheo B, Briickner Hans

Biological studies of the peptide Hy-al and analogs 2-07-148 312

Crusca Jr Edson, Rezende Adrielle, Marchetlo Reinaldo, Castro Mariana S, Fontes Wagner,

Cilli Eduardo M

Application of non-sequential pharmacophore concept for design of antimicrobial 2-07-149 314

peptide dendritners

Urbancz)>k-Lipkowska Zofia, Polcyn Piotr, Janiszewska Jolanta

Enhancement ofAntimicrobial Activity of a Natural Antimicrobial Neuropeptide of 2-07-150 316

Sepia officinalisLaurencin Mathieu, DuvalEmilie, Zatylny-Gaudin Celine, Hemy Joel, Baudy-FIoc 7; Michele

New bradykinin B2 antagonists - influence ofC-terminal modifications on their 2-07-151 318

pharmacological properties

ileszynska Malgorzata, Kwiatkowska Anna, Sobolewski Dariusz, Wierzba Tomasz,

Katarzynska Joanna, ZabrockiJanitsz, Borovickovd Lenka, Slaninovd Jifina, Prahl Adam

Design synthesis and biological activities of temporin A and temporin L analogues 2-07-152 320

Malfi Stefania, Auriemma Luigia, Saviello Maria Rosaria, Marcozzi Cristina,

CarotenutoAlfonso, Campiglia Pielro, Gomez-Monterrey Isabel Maria,

Mangoni Maria Luisa, Marcellini Hercolani Gaddi Ludovica, Novellino Ettore,

Grieco Paolo

Comparative structural studies of potent neuroprotective peptides ofthe humanin family 2-07-153 322

Benaki Dimitra, Zikos Christos, EvangelouAlexandra, Slaninovd Jifina, Vlassi Metaxia,

Livaniou Evangelia, Mikros Emmanuel, Pelecanoit Maria

In vitro and in vivo antitumor effect of symmetric GnRH-IH dimer derivatives 2-07-154 324

Szabo Ildiko, Bosze Szilvia, Orbdn Erika, Vincze Borbala, Gadl Dezso, Csuka Orsolya,Hudecz Ferenc, Mezo Gdbor

Delta Sleep Inducing Peptide (DSIP) its analogues and Deltaran®: biological activity 2-07-156 328

and mode of action

Mikhaleva Inessa, Prudchenko Igor, NurbakovAlfred, Sapozhnikov Alexander,

Ivanov Vadim

Antiviral (HSV) activities of selected insect peptides 2-07-157 330

Kuczer Mariola, DziubasikKatarzyna, Midak-Siewirska Anna, Zahorska Renata, Litczak MirostaM;

Konopinska Danuta

Creation of novel spider toxin analogs to adopt as probes for visualization of 2-07-158 332

glutamate receptors

Wakamiya Tateaki, Nishimaru Takahiro, Mori Kiyoe, Yamaguchi Yoshihiro

Neurotensin analogs with high affinity and selectivity at human neurotensin receptor 1 2-07-159 334

Bednarek Maria A, Tang Rui, DavisAmber, WeinbergDavidH

Sequence analysis and solid phase synthesis ofturtle (S-defensin TBD-1 2-07-160 336

Knappe Daniel, Stegemann Christin, KolobovJr. Alexander, Shamova Olga, Kokryakov Vladimir N,

Hoffmann Ralf

XXXIV

Bioactive peptides

Trichogin GAIV is able to bind Ca(II) and lanthanide ions 2-07-161 338

Gallo Emamiela, Stella Lorenzo, Bocchinfuso Gianfranco, PalleschiAntonio, FormaggioFernando, Toniolo Claadio, Venanzi Mariano

Three-dimensional structure and mechanism of action of an antifungal peptide 2-07-162 340

generated from hemocyanin cleavage in a penaeid shrimpPetit Vanessa, BlondAlain, Djediat Chakib, Peduzzi Jean, Dupont Joe'lle, Bachere Evelyne,

Destoumieux-Garzon Delphine, Rebuffal Sylvie

Structural studies on human neuropeptide FF 2-07-163 342

Thuau Romain, Segalas-Milazzo Isabelle, Chartrel Nicolas, Coadou Gael,

Lameiras Pedro, Davoust Daniel, Guilhaudis Laure

Structural comparison of//-opioid receptor selective peptides and peptidomimetics 2-07-164 344

revealed four important conformational parameters ofbioactivityBoricsAttila, Toth Geza

Novel chitosan-pexiganan conjugate for the treatment of infected diabetic foot ulcers: 2-07-165 346

synthesis and characterization by FT1R and AAA

Batista Mary, Adeva Alberto, Gallemi Marcal, Gomes Carlos, Gomes Paula

Synthesis and biological activities ofendomorphin-2 analogues containing Pro mimics 2-07-166 348

Tsuda Yuko, Miyazaki Anna, Yamada Takashi, Isozaki Kaname, Shimohigashi Yasiiyuki,Ambo Akihiro, Sasaki Yusuke, Minour Katsuhiko, In Yasuko, Ishida Toshimasa,

Okada Yoshio

Biological evaluation of new arginine vasopressin (AVP) analogues containing non 2-07-167 350

natural amino acids

Magafa Vassiliki, Pappa Eleni, Borovickovd Lenka, Pairas George, Slaninovd Jifina,

CordopatisPaul

Structure-activity relationship studies of pituitary adenylate cyclase-activating 2-07-168 352

polypeptide: Ala-scan of the TV-terminal domain

Bourgault Steve, Vaudry David, Doan Ngoc Due, Laburthe Marc, Couvineau Alain,

Vaudry Hubert, FournierAlain

The siderophore microcin family: from the genetic systems to the antimicrobial peptides 2-09-169 354

Vassiliadis Gae'lle, Peduzzi Jean, Rebuffal Sylvie

Peptidomics of grape 2-10-172 356

BorchikivAlexander, Zamyatnin Alexander

The effect ofthe so called "/?-sheet breakers" (BSBs) on Aft 1-42 aggregates 2-11-173 358

Sods Katalin, HetenyiAnasztdzia, Fiilop Livia, Laczko Ilona, Martinek Tamds, Penke Botond

Designing trehalose-conjugated peptides for the inhibition ofAlzheimer's Aft 2-11-174 360

oligomerization and neurotoxicityDe Bona Paolo, Giuffrida Maria Laura, Copani Agata, Pignataro Bruno,

Attanasio Francesco, Cataldo Sebastiano, Pappalardo Giuseppe, Rizzarelli Enrico

Conformational studies of cyclolinopeptideA analogues modified by/^-prolines 2-11-175 362

Mazur Adam, Katarzynska Joanna, Zabrocki Jamtsz, Jankowski Stefan

The synthesis and structural study ofiso-A/?(l-42) 2-11-176 364

Bozso Zsolt, Penke Botond, Juhdsz Gdbor, Szegedi Viktor, Laczko Ilona, Sods Katalin,

Simon Dora, Fiilop Livia

Oligopeptide-porphyrin interactions: the effects of the porphyrin metalation and axial 2-11-177 366

ligation on peptide matrix conformation

Setnicka Vladimir, HlavdcekJan, Urbanova Marie

Conformational and thermal stability of sequential cationic oligopeptides (Lys-Ala- 2-11-178 368

Ala)„ in aqueous solution

Setnicka Vladimir, HlavdcekJan, Urbanova Marie

XXXV


Spin-label aided investigation of feline immunodeficiency virus Gp36 derived peptide 2-12-179 370

in presence of membrane models

Grimaldi Mamiela, D 'Errico Gerardino, Scrima Mario, Esposito Cinzia,

Giannecchini Simone, Bendinelli Mawo, Rovero Paolo, Marsh Derek, D 'UrsiAnna Maria

Effect offlavonoids on AfJ-25-35 -DLPC vesicle interaction 2-12-180 372

TedeschiAnnamaria, Lauro Maria Rosaria, Grimaldi Mamiela, D'Errico Gerardino,

D'UrsiAnna Maria, Aquino Rita Patrizia

A//16-35 peptide: structural features in membrane mimicking systems 2-12-181 374

Grimaldi Mamiela, Scrima Mario, Esposito Cinzia, Tedeschi Annamaria,

D 'Ursi Anna Maria

Towards a Vaccine Against Multiple Sclerosis 2-14-182 376

Katsara Maria, Deraos George, Matsoukas John M, Apostolopoulos Vasso

Synthesis and biological evaluation of novel peptides influencing angiogenesis 2-14-183 378

Horvath Aniko, Knedlitschek Gudrun, Okada Yoshio, MiyazakiAnna, Vantus Tibor, Seprodi

Jdnos, Varga Andrds, Tanai Henrietta, Bokonyi Gydrgyi, Hiebl Bernhardt Keri GyGrgy

A RGD tetracyclopeptide as a new tool for specific tumor cell targeting 2-15-184 380

Schmidt Julien, Robert Bruno, Garambois Veroniqne, Rocheblave Luc, Martinez Jean,

Pelegrin Andre, Cavelier Florine, Vives Eric

Identification ofbiologically active peptides from the N-terminal domain oflaminin 2-16-185 382

alpha 2 chain

Hayashi Takemitsu, Urushibata Shunsuke, Kobayashi Kazuki, Ishikawa Masaya,Hozumi Kentaro, Kikkawa Yamato, Nomizu Motoyoshi

New integrin ligands based on isoDGR sequence 2-16-186 384

Otto Elke, Heckmann Dominik, Zahn Grit, Stragies Roland, Kessler Horst

Development ofGnRH-IIl anthracycline conjugates as drug delivery systems for 2-18-187 386

targeted chemotherapyManea Marilena, Szabo Ildiko, Orbdn Erika, Bosze Szilvia, Tejeda Miguel, Gaal Dezso,

Kapuvdri Bence, Csdmpai Antal, Radnai Laszld, Mezo Gabor

Dimeric ct-MSH analogues carrying DOTA for melanoma tumor targeting 2-18-189 388

Tanner Heidi, Bapsi Jean-Philippe, Calame Marline, EberleAlex N

Protein delivery with transportans avoids recycling endosomal route and is not 2-19-190 390

potentiated by EGF

SddlikPille, Rda'gel Helin, Hansen Mats, Langel Ulo, Pooga Margus

Novel intracellular delivery system using pH-dependent fusiogenic peptide 2-19-191 392

NakaseIkuhiko, Kobayashi Sachiko, Kawabata Noriko, Futaki Shiroh

Interaction of S4(13)-PV peptide with plasma membrane and cell entry. 2-19-192 394

An electron microscopy view

KoppelKaida, Padari Kdrt, Lorents Annely, Mano Miguel, RaidRaivo,Pedroso de Lima Maria, Pooga Margus

A Modular Strategy for the Design of Apoptogenic Cell Penetrating Peptides 2-19-193 396

Jones Sarah, Howl John

Multifunctional Peptides Analogues Of Tyr-MIF 2-20-194 398

Lipkowski Andrzej W, Kosson Piotr, Tsuda Yuko, Okada Yoshio

Synthesis of conformational^ restricted analogues of GnRH-I and GnRH-III and 2-20-195 400

studies on prostate cancer cell proliferationPappa Eleni V, ZotnpraAikaterini A, Magafa Vassiliki, Diamantopoulou Zoi,Lamari Fotini N, Katsoris Panagiotis, Cordopatis Paul

XXXVI

Bioactive peptides

Apoptotic effect of peptides produced by clastase I hydrolysis of bone proteoglycan 2-21-196 402

extract

McLaughlin Rene, Johnson Keryn, Harper Jacquie, Vasudevamurthy Madhusudan

Opioid peptide-platinum(II) complexes: synthesis characterization and in vitro 2-21-197 404

antitumor activity

GlowinskaAgnieszka, Tomczyszyn Aleksandra, Kosson Piotr, Malalinska Joanna,

Lipkowski Andrzej W, Misicka Aleksandra

Bioinformatic-aided studies of biological activity of food peptides and proteins 2-22-198 406

Darewicz Maigorzata, Dziuba Jerzy

Search for modulators of VEGF-KDR interaction: hydrocarbon-bridged VEGF 2-23-199 408

derived peptidesGarcia-Aranda M. Isabel, Mirassou Yasmina, Mirones Isabel, Alfranca Arantza,

Martin-Martinez Mercedes, Garcia-Lopez M. Teresa, Jimenez M. Angeles, Redondo Juan M,

Gonzalez-Muniz Rosario, Perez de Vega M" Jesus

Cyclic peptides comprising constrained amino acids as inhibitors of integrin-ligand 2-23-200 410

interaction

Royo Soledad, Conradi Jens, SewaldNorbert

Conjugation of RGD analogs with o-quinone methides of [ll 'jbinaphthalenyl and 2-23-201 412

their biological activity

Sarigiannis Yiannis, Saravanos Antonios, Stavropoulos George, Tsoungas Peter,

Cordopaiis Paul

Analysis of POl-PO interaction using fluorescent labeled analogs designed based on 2-23-202 414

"camouflaging substitution"

Yoshida Rinako, Awada Chihiro, Takao Toshifumi, Sato Takashi

Linear and cyclic synthetic peptide analogs of the A2 subunit (sequence 558-565) of 2-23-203 416

the factor Villa blood coagulation and their biological effects

Anastasopoulos Charalampos, Sarigiannis Yiannis, Stavropoulos George,

Liakopoulou-Kyriakides Maria, Makris Pantelis

Effect of4-iJ-Hydroxy-L-proline (Hyp) on peptide conformation and SH3 affinity 2-23-204 418

Ruzza Paolo, Siligardi Gwliano, Hussain Rohanah, Calderan Andrea, Guiotto Andrea,

Biondi Barbara, Cesaro Luca, Donella-Deana Arianna

Binding of Peptides to GPCRs - A Molecular Docking Approach with PSO@Autodock 2-23-205 420

Namasivayam Vigneshwaran, SchildEnrico, Gunther Robert, Beck-Sickinger Annette G

Peptides from a Phage Display Library Recognize of Modified Nucleosides of 2-25-206 422

Anticodon Domain of Human tRNALys3Rekowski Piotr, Mucha Piotr, Kozlowska Anna, Ruczynski Jaroslaw, Agris Paul F

GnRH analogs as carriers for targeted suicide gene delivery 2-25-207 424

Burov Sergey, Yablokova Tatyana, Dorosh Marina, Orlov Sergey, Ignatovich Irina

Molecular Modeling of GnRH analogues in DMSO solution using Nuclear Magnetic 2-28-208 426

Resonance (NMR) and Molecular Dynamics (MD)Laimou Despina, Mantzowani Efthimia, Plaits Jamie, Matsoukas Minos-Tim otheos,

Troganis Anastasios, Tselios Theodore


XXXVII

Proceedings ofthe 3(1"' European Peptide Symposium Helsinki, Finlandia Hall, 2008

Cell Adhesive Laminiii Peptides for Tissue Engineering 3-05-001

Nomizu Motoyoshi, Otagiri Dai, Fujimori Chikara, Hozumi Kentaro, Kikkawa Yamalo

Photocurrent generation in peptide-based self-assembled monolayers functionalized 3-11-002 430

with electron transfer antenna chromophoresGatto Emanuela, Stella Lorenzo, Formaggio Fernando, Toniolo Claudia, Venanzi Mariano

Neoglycopeptides as glycoprobes for lectin-carbohydrate interaction studies by SPR 3-13-003 432

Jimenez-Castells Carmen, de la Torre Beatriz G, Gutierrez-Gallego Ricardo, Andreu David

Involvement of alpha-helix 2 domain in prion protein conformationally-induced diseases 3-14-004 434

Ronga Luisa, Palladino Pasquale, Rossi Filomena, Pugniere Martine, Roquet Francoise,

Amblard Muriel, Martinez Jean, Benedetti Ettore

A leptin receptor agonist glocopeptide for leptin replacement therapy 3-15-005 436

Otvos Laszlo, Cassone Marco, Wade John D, Knappe Daniel, Hoffmann Ralf, HenryBelinda, Clarke lain, Surmacz Eva

Peptide-based immunoassays for biomarkers detection: a challenge for translational 3-18-006 438

research

Papini Anna Maria

Synthesis and Evaluation of RGD Peptide Analogs Cyclized by Coordination of 3-18-007 440

Oxorhenium and Oxotechnetium Cores for Molecular Imaging of Cancer

Auforl Marie, Gonera Marta, Dubs Pascaline, Czarny Bertrand, Thai Robert,

Le Clainche Low, Masella Michel, Servent Denis, Dugave Christophe

Synthesis of smart potential MRI contrast reagents that bind aggregated fl amyloid 3-26-008 442

for the diagnosis fAlzheimer's disease

Austen Brian, Mohammed Yeser, Cheng Elliott, Malharu Balpreet

Submitted papers: 8

Semi-synthetic approaches to glycosylation ofMOG as autoantigen in Multiple 3-03-101 444

Sclerosis disease

GoriFrancesco, Mulinacci Barbara, PapiniAnna Maria, Rovero Paolo,

Beck-Sickinger Annette G

Different proteases immobilized inside chitosan film can catalyze synthesis and 3-03-102 446

hydrolysis of peptide substrates

Bacheva Anna V, Macquarrie Duncan J, Filippova Irina Yu

Cell Adhesion Ability of Self-Assembled Nanofiber Consisting of RGDS-Tagged 3-05-103 448

Amphiphilic Peptide

Higashi Nobuyuki, Kawamura Yoko, Koga Tomoyuki

AKTA oligopilot for Automated Solid Phase Peptide Synthesis 3-06-104 450

Tedebark Ulf, Latassa Daniel, Heinzmann Etienne, Denker Per, HolmbergLars,Uhlen Kristina, KarlbergPer, Werbitzky Oleg, Strong Andrew

Using the activity-based approach to identify neuropeptide-processing proteases 3-07-105 452

Sabido Eduard, Tarrago Teresa, Giralt Ernest

A flow cytometric method to detect internalization of antimicrobial fluorescently- 3-07-106 454

labeled peptides in bacterial cells

Gennaro Renato, Benincasa Monica, Pacor Sabrina, Carlini Gianluigi, Tossi Alessandro,Scocchi Marco

XXXVIII

Peptide biotechnology and diagnostics

Synthesis and Characterization of a Molecular Force Balance based on Peptide Epitopes 3-13-107 456

DavidRalf, Ho Dominik, Gaab Hermann E

Totally synthetic collagen-like gels by intermolecular folding of designed peptides 3-13-108 458

Yamazaki Chisato M, Asada Shinichi, Kilagawa Kouki, Koide Takaki

Towards a fully synthetic "phage-display like" system for high-throughput screening. 3-13-109 460

Khandadash Raz, Partouche Shirty, Marge] Shlomo, Byk Gerardo

Molecular-weight distribution and structural transformation in water-soluble 3-14-110 462

conjugates ofpoly(acrylic acid) and synthetic peptide

Mansuwglti Bami, Topuzogullari Mural, Akdesle Zeynep

A new stable Copper(III)/Cyclopeptide complex: structural characterization by 3-15-111 464

XANES and EXAFS studies

Pratesi Alessandro, Giuli Gabriele, Cicconi Maria Rita, Pratesi Giovanni, Ginanneschi Mauro

The role of deiminated protein antigens in the diagnosis of Rheumatoid Arthritis 3-15-112 466

Magyar Anna, Neer Zsuzsa, Szarka Eszter, Hudecz Ferenc, Sarmay Gabriella

New selective substrates for detection of cysteine proteinases 3-15-113 468

Semashko Tatiana, Popletaeva Sofia, Oksenoit Elena, Lysogorskaya Elena, Filippova Irina

Yu

Post translational modified peptide-based ELISA to detect autoantibodies in Primary 3-15-114 470

Biliary Cirrhosis

Innocenti E/isa, Peroni Elisa, Nuti Francesco, Chelli Mario, Rovero Paolo, Selmi Carlo,

Papini Anna Maria

Development of CelluSpot method for serodiagnosis of human parvovirus B19 infections 3-15-115 472

Hepojoki Jussi, Brandt 01e, Frank Ronald, Kaikkonen Leena, Soderlund-Venermo Maria,

Hedman Klaus, Lankinen Hilkka

Design and synthesis of aminoacyl esters of unprotected saccharides as potent 3-15-116 474

inhibitors of angiotensin converting enzyme (ACE)Stoineva Ivanka, Ivanovo Galya, Tchorbanov Bozidar

""'Tc-labeled Tetraamine-Derivatized Cyclic Nonapeptides with Pansomatostatin-like 3-15-117 476

Properties: Synthesis and Comparative Biological Evaluation

Nikolopoulou Anastasia, Petrou Christos, Zompra Aikaterini A, Charalambidis David,

Nock Berthold Artw; Waser Beatrice, Cescato Renzo, ReubiJean Claude, Cordopatis Paul,

Maina Theodosia

Introduction of Hydrophilic Asp-Residue(s) in ["'"TclDemotate 1: A Structure - 3-15-118 478

Activity Relationships StudyNock BertholdArtur, Petrou Christos, Galanis Athanassios S, NikolopoulouAnastasia,Waser Beatrice, Reubi Jean Claude, Cordopatis Paul, Maina Theodosia

Adrenomedullin analogs: potential diagnostic tools for pulmonary circulation imaging 3-15-119 480

Letourneau Myriam, Fit Yan, Nguyen Quang Trinh, Hare! Francois, Dupuis Jocelyn,Fournier Alain

Production of peptide arrays consisting of labeled structured peptide and 3-16-120 482

glycopeptide libraries for the construction ofprotein detection systemsNokihara Kiyoshi, Hirata Akiyoshi, Kawasaki Takayastt, Miyazato Naeko, Kodama Yukiko,

Ono Noriko, Sogon Tetsuya, Suzuki Kanae, Miyajima Midori, Kawahira Nobom,

Ohyama Takafumi

A Compact Disc-sized biochip structured and functionalized by microplasma-based 3-16-121 484

patterned amination as substrate for an automated chemical synthesizerFranke Raimo, Hinze Alena, Lucas Nina, Biittgenbach Stephanas, Klages Clans-Peter,

Frank Ronald

XXXIX


Cellular Activity ofAntisense CatLip PNA Conjugates 3-19-122 486

Shiraishi Takehiko, Nielsen PeterE

New Strategy for Protein Identification-Improving Signal Intensity and Sensitivity of 3-26-123 488

MALDI Mass Spectrometry by Specific Peptide Derivatization

Camel Soma, Valmalle Charlene, Subra Gilles, Enjalbal Christine, Martinez Jean

Synthesis and evaluation of peptide analogues as functional probes targeting matrix 3-27-124 490

metalloproteinasesPlanner Hannes Patrik, Collet Magalie, Hoess Eva, Lenger Janina, Pestlin Gabriele,

SewuldNorbert

The Potential Stem-Forming Sequence Consists of the2-Stranded fi-Structure in Prion Proteins 3-28-125 492

Saiki Masatoshi, Hidaka Yaji, Nara Msayuki, Morii Hisayuki

Submitted papers; 25

CREDEX-MS: Molecular elucidation of carbohydrate recognition peptides in lectins 4-01 -001 494

and related proteins by proteolytic excision- mass spectrometry

Przybylski Michael, MoiseAdrian, Siebert Hans-Christian, Gabins Hans-Joachim

Novel non-peptide ghrelin receptor ligands based on 124-trisubstituted triazoles 4-07-002 496

BlayoAnne-Laure, Moulin Aline, Demange Luc, Dickson Suzanne L, GalleyrandJean-Claude, Locatelli Vittorio, Torsello Antonio, PerrissoudDaniel, Martinez Jean,

Fehrentz Jean-Alain

The proline-rich antimicrobial peptide dimerA3-APO and its single chain in vivo 4-13-003 498

metabolite represent a new paradigm in microbiology pharmacology and drug developmentCassone Marco, Vogiatzi Paraskevi, Wade John D, Rozgonyi Ferencz, Szabo Dora,

Kocsis Bela, Otvos Laszlo

Naposomes: A new class of peptide containing supramolecular aggregates as target 4-18-004 500

selective delivery systems.MoriscoAnna, Accardo Antonella, Tesauro Diego, Benedetti Ettore, Pedone Carlo,Morelli Giancarlo

New approaches to the design synthesis and biochemical and biophysical evaluation of 4-20-005 502

heteromultivalent ligands for detection and treatment of cancer

Hruby Victor, Josan Jatinder, Vaguer Joseph, Fernandes Steve, Handl Heather, Xu Liping,Lynch Ronald, Mash Eugene, Gillies Robert

Rational Design of HighlyActive and Selective o^p, Integrin Antagonists 4-21 -006 504

Laufer Bwkhardt, Heckmann Dominik, MeyerAxel, Marinelli Luciana, NeabauerStefanie,Zahn Grit, Stragies Roland, Kessler Horst

N-methyl phenylalanine-rich peptides as potential blood brain barrier shuttles 4-28-007 506Malakoulikhah Morteza, Teixido Meritxell, Giralt Ernest

Submitted papers: 7

Esters ofPurine Nucleosides (Abacavir) with Natural and Unnatural Amino Acids 4-01-101 508

-Synthesis and Cytotoxicity in Cell Culture

GenovaPetia, Chayrov Radoslav, Argirova Radka

Development ofvV-acyl amino acid bisphosphonate amide derivatives as potent bone 4-01-102 510

metastatic prostate anti-cancer agentsGera Lajos, Wu Daqing, Seo Seongil, Chan Daniel C, StewartJohn M, ChungLeland WK

XL

Pharmacology and medicalpeptide chemistry

Novel potent and selective Angiotensin IV short analogues 4-01-103 512

Lukaszuk Aneta, Demaegdt Heidi, Karoyan Philippe, Vanderheyden Patrick,

Vauquelin Georges, Tourwe Dirk

Improving pharmacokinetic properties of radiolabeled bombesin analogues by 4-01-104 514

incorporation ofpolar groups

Brans Luc, Maes Veronique, Garcia-Garayoa Elisa, Schweinsberg Christian, Daepp Simone,

Schibli Roger, Blauenstein Peter, Tourwe Dirk

Chemical Stability of Some Purine Analogues 4-04-105 516

Stankova Ivanka, Hristov Georgi, Dzimhova Taliana

A Novel Approach To Improve Cellular Delivery Of 5-Aminolaevulinic Acid: New 4-05-106 518

5-ALA-containing Peptide Prodrugs For Photodynamic TherapyGiuntini Francesco", Bourre Ludovic, MacRobert Alexander J, Wilson Michael,

Eggleston Ian M

Determination of Binding Ratio ofHydrofobic Peptide-Polymer Conjugates by Using 4-05-107 520

Fluorescamine Assay

Budama Ballal Yasemin, Derman Scrap, Mansuroglu Bami, Mustafaeva Zeynep

Peptides from CcdB protein as novel inhibitors ofDNA gyrase 4-07-108 522

Marchetto Reinaldo, Garrido Saulo S, Barros Ronaldo S, Trovatti Eliane, Cotrim Camila A

Synthesis and Biological Activity of a Series ofAza-/f3-Pseudopeptides Related to 4-07-109 524

26RFa The Endogenous Ligand of GPR103

Le Marec Olivier, Neveu Cindy, Tasseau Olivier, Guilhaudis Laure, Segalas-MilazzoIsabeHe, Lefranc Benjamin, Tena-Sempere Manuel, Tonon Marie-Christine, Baudy-Floc 'h

Micbele, Vaudry Hubert, Leprince Jerome

Effect of Synthetic Peptides against Multi-Drug Resistant Bacteria from Otitis Media 4-07-110 526

Park Yoonkyung, Jeong Nari, Park Hae-Kyun, Kim Mi-Hyun

Development of biotin-tagged diketopiperazine based anti-microtubule agents and 4-07-111 528

tubulin photoaffinity labelingYamazaki Yuri, Kohno Kyoko, Yasui Hiroyuki, Kiso Yoshiaki, Neuteboom Saskia,

BarralAna M, Potts Barbara, Lloyd G Kenneth, Hayashi Yoshio

New all non-aromatic vasopressin Via receptor agonists 4-07-112 530

Wisniewski Kazimierz, Galyean Robert, Schteingart Claudia, Taki Hiroe, Alagarsamy

Sudar, Croston Glenn, Heitzmann Joshua, Kohan Arash, Wisniewska Halina, Laporte

Regent, Riviere Pierre

The Impact of Lithium Cations on the Peptide Bond 4-11-113 532

Kunz Claudia, Berger Stefan, Fischer Giinter, Hofmann Hans-Jorg

Microwave Assisted Synthesis of Polyelectrolytic Bioconjugates of Hepatitis B Surface 4-14-114 534

Antigenic Polypeptides and Their Immunological Properties

Mustafaeva Zeynep, OzdemirZafer Omer, Iscani Basak, Karabulut Erdem, B Battal Yasemin

Synthesis and utilization of peptide adhesives for medical application 4-14-115 536

Rawer Stephan, Schauer Frieder, Lindequist Ulrike, Wende Kristian, Jiilich Wolf-Dieter

Chimeric opioid-neurotensin ligands as new prospective analgesics in chronic pain 4-15-116 538

Kleczkowska Patrycja, Ruszczynska-Bartnik Katarzyna, Kaczorowska Ewa,

Ejchart Andrzej, Kosson Piotr, Tourwe Dirk, Lipkowski Andrzej W

Multi-component fluorescence labeling method for efficient positional screening of 4-16-117 540

peptide libraryKitamatsu Mizuki, Kuroiwa Hiroyuki, Sakata Daisuke, Yamamoto Takahiro, Inoue Keisuke,

Kishimoto Yoshiko, Futami Midori, Sisido Masahiko

XLI


Study of spillover tritium reaction with insulin 4-17-118 542

Yaskovsk)' Boris, Zololarev Ywii, ShepelElena, KsenojbntovAlexander, Murashev Arkadi,

Dadayan Alexander, Semushina Svetlana, PakhomovaIrina, Kozik Valerii, Myasoedov Nikolai

BioShuttle for Temozolomide Transport into Prostate Cancer Cells 4-19-119 544

Pipkorn Riidiger, Waldeck Waldemar, Didinger Bemd, Wiefiler Manfred, Braun Klaus

Analogues of the kinin Bl receptor antagonist R-954 bearing JV-terminal lipid moieties 4-19-120 546

Neugebauer Witold, Savard Martin, Elkara Soma, Sirois Pierre, Gobeil FernandJr

Peptide conjugates of new insilico identified drug candidates and first/second line 4-19-121 548

antituberculars - design synthesis and antimycobacterial effect

Horvati Kata,- Mezb Gabor, Szabo Ildiko, Szabo Nora, Grolmusz Vince, Hudecz Ferenc,

Bosze Szilvia

CPPor cholesterol conjugation to antisense PINA for cellular delivery 4-19-122 550

Joshi Rajendra, Mishra Ritu, Su Wu, Engelmann Joern

The Evaluation of the Effect of Japanese Herbal (Kampo) Medicines using Bioavtive 4-20-123 552

Peptides as Biomarkers

Katagiri Fumihiko, Sato Yuhki, Itoh Hiroki, Takeyama Masaharu

Design and synthesis of a tripartate paclitaxel prodrug for melanoma therapy 4-20-124 554

RuzzaPaolo, NassiAlberto, Marchiani Anna, Rondina Maria, Rosato Antonio,

Rossi Carlo Riccardo, Mammi Stefano, Floreani Maura, Quintieri Luigi

Synthetic immunoactive fragments of endogenous proteins: selection and application 4-21-125 556

for diagnostics and immunotherapy

Volpina Olga, Kamvnina Anna, Shalgwiov Vladimir, Akhidova Elena, Volkova Tatyana,Koroev Dmitriy, Filatova Margarita, Kormakova Tatyana, Bobkova Natalya,Vladimirova Natalya

Allosteric inhibition and activation of SHP-1 phosphatase by SH2 phosphopeptide ligands 4-23-126 558

Teichmann Kathleen, Hampel Kornelia, ImhofDiana

Size and Zeta Potential Analysis of Synthetic Pepride-Carrier Protein Conjugates 4-23-127 560

Depend on the Time

Deiman Serap, Dalgakiran Eray, Mustafaeva Zeyrtep

Peptide drugability: Analytical functionality 4-26-128 562

De Spiegeleer Bart, Van de Wiele Chrislophe, Burvenich Christian, Van Dorpe Sylvia,Vergote Valentijn, Baert Bram, Peremans Kathelijne, Audenaert Kurt


Determination of GPCR structures and activation mechanisms with reactive peptide probes 5-07-001 564ArsenaultJason, Clement Martin, Pillion Dany, Beaulieu Marie-Eve, Holleran Brian,Leduc Richard, Guillemette Gaetan, Lavigne Pierre, Escher Emanuel

Submitted papers: 1

Protein-oligopeptide fragmentomics 5-22-101 566ZamyatninAlexander

Folding patterns for double helices in a-peptides 5-22-102 568Schramm Peter, Hqfmann Hans-Jdrg

XLII

Bioinformalics and systems biology

Cryptic signal: A novel signaling mechanism involving cryptides

Mukai Hidehilo, Ueki Nobuhiko, Wakamatsu Kaori, Kiso Yoshiaki

The binding of peptides containing tyrosine residue to B-cycIodextrin

Czaplewski Cezary. Czaplewska Paulina, Romankiewicz Justyna, Wiczk Wieslaw

Submitted papers: 4

5-24-103

5-28-104

570

572

Artificial intelligence delivers superb antibiotics for superbugs

Jenssen Havard, Hilperl Kai, Fjell Christopher D, Waldbrook Mall, Mullaly Sarah D,

Volkmer Rudolf, CherkasovArtem, Hancock Robert EW

Submitted papers: 1

6-07-001 574

Design and synthesis of asymmetric //-Sandwich Proteins 6-01-101 576

Frilzemeier Kai, Haehnel Wolfgang

NMR solution structure analysis of the active and inactive fragments of pheromone 6-07-102 578

biosynthesis-activating neuropeptide (PBAN) from the silkmoth Bombyx mori

Nagata Koji, Okada Akitoshi, Ohtsuka Jun, Takahashi Mihoko, Kawai Takeshi,

Sagisaka Arisa, Hull JJoe, Moto Ken-ichi, Matsumoto Shogo, Nagasawa Hiromichi,

Tanokura Masani

Membrane interactions of primate antimicrobial cathelicidins LL37 and RL37 6-07-103 580

Morgera Francesco, Antcheva Nikolinka, Scaini Denis, Pacor Sabrina, Vaccari Lisa

Azobenzene-mediated photomodulation of a collagen triple helix monitored by IR spectroscopy 6-11 -104 582

Lorenz Lisa, Kitsebauch Ulrike, Moroder Luis, Wachlveitl Josef

Are V57 mutants of amyloidogenic protein - human cystatin C more or less resistant 6-11-105 584

to denaturation conditions?

Jankowska Ekbieta, Orlikowska Marta, Radulska Adrianna, SzymanskaAnela

Molecular dynamics study of //-peptides: 6-11 -106 586

Using computer simulation to correct and interpret experimental data

Gattin Zrinka, van Gunsleren Wilfred F

Nanomolar aggregation of amyloid beta peptides covalently and site-specifically 6-11-107 588

modified by cholesterol oxidation productsUsuiKenji, Powers Evan, Paulsson Johan, Siegel Sarah, Kelly Jeffeiy

Hairpin peptide inhibitors of amyloid fibril formation 6-11-108 590

Huggins Kelly, Andersen Niels

Structural Studies on the Membrane-Reconstituted Transmembrane-Juxtamembrane 6-11-109 592

Region of ErbB2/Neu(647-693)Matsushita Chihiro, Sato Takeshi, Furukawa Yusuke, Smith Steven O, Aimolo Saburo

An End-cap for Enhancing Hairpin Stability 6-11-110 594

Kier Brandon, Andersen Niels

Interaction ofthe minimal active peptide sequence ofhuman growth hormone 6-12-111 596

releasing factor with negatively charged liposomesThomas Lars, Weigelt Heiko, Kohler Guido, Zschornig Olaf

Artificial esterases formed by self-organization ofN-lipidated tripeptides of a catalytic 6-12-112 598

triad immobilized on cellulose

Kujawska Nina, Kaminski Zbigniew J, Fraczyk Justyna

XLIII


A comparative study on lipid affinity of cell penetrating peptides in presence or 6-12-113 600

absence of cargo

Biondi Barbara, CalderanAndrea, Guiotto Andrea, Ruzza Paolo

Kinetic Study of Liposome Adsorption to a Peptide-modified Au Electrode for 6-12-114 602

Applications in Biomembrane Sensors

Kasuya Yuzo, Nosaka Shizuka, Yamada Daisuke, Ikeda Yasuyiiki, Matsumura Kazunari

Fraternal twins! y-peptide and oligoureas are isosteric isostructural foldamers 6-17-115 604

endowed with yet distinct biomolecular recognition propertiesClaudon Paul, Violette Aude, Lamour Karen, Foumel Sylvie, Heuriauli Beatrice,

GodetJulieii, Jamart-Gregoire Brigitte, Averlant-Pelit Marie-Christine, BriandJean-Paul,

Duporail Guy, Monteil Henri, Guichard Gilles

Temperature dependant methionine proximity assay highlights conformational 6-17-116 606

variations occurring through the mechanism of peptidergic GPCR activation

Arsenaull Jason, Clement Martin, Leduc Richard, Guillemette Gaelan, Lavigne Pierre,

Escher Emanuel

New analytical methodology for the characterization of synthetic polypeptides 6-26-117 608

Miramon Helene, Cottet Herve, Martinez Jean, Cavelier Florine

Conformational analysis of the new temporin analogues: Gln'TAand Pro'TL 6-28-118 610

Saviello Maria Rosaria, Cavalli Andrea, Malfi Stefania, Campiglia Pietro, Gomez-

Monterrey Isabel Maria, Mangoni Maria Luisa, Novellino Ettore, Grieco Paolo,

Carotenuto Alfonso

Synthesis and characterization of the collagen model peptides containing 4(S)-hydroxyproline 6-28-119 612

Motooka Daisuke, Kawahara Kazuki, Sato Nozomi, Nakamura Shota, Uchiyama Susuma,

Doi Masamiisu, Nishiuchi Yuji, Nakazawa Takashi, Yoshida Takuya, Ohkubo Tadayasu,Nishi Yoshinori, Kobayashi Yuji


/(-sheet antimicrobial peptide cateslj tin generates rigid domains for membrane permeationJean-Francois Franlz, Elezgaray Juan, Metz-Boutigue Marie-Helene, Diifoiirc Erick

Submitted papers: 1

7-13-001 614

Degradation product of desmopressin in phosphate/citrate buffer

NylanderBo, Malm Mattias, Walhagen Karin, Nilsson Anders

Unusual Cleavage ofTripeptides Containing Pipecolic AcidIslam Md Nurul, Shankar Sonu Ram, Kato Tamaki, Nishino Norikazu

Analysis of protein-protein interaction sites without natively folded protein samples:Action or fact?

MalesevicMiroslav, Pohlmann Angela, Liicke Christian, Trdger Mario, Jahreis Gunther,Hernandez-Alvarez Birte, Bordusa Frank, Fischer Giinter

Improved expressed protein ligation method for consecutive coupling of polypeptidefragments

Tomboly Csaba, WelkerErvin

Cellular peptidomics: peptide sets produced by rat hepatocytes in vitro

Sazonova Olga, Yatskin Oleg, Khachin Dmitry, Kudryavtsev Denis, KarelinAndrei,Ivanov Vadim

7-01-101 616

7-01-102 618

7-02-103 620

7-05-104 622

7-10-105 624

XLIV

Peptide biophysics and lipid-peptide interactions

Spectroscopic characterization of doppel peptide fragments and their complex species 7-11-106 626

with Cu (II)

La Mendola Diego, Magri Antonio, Bonomo Raffaele P, Rizzarelli Enrico, Hansson Orjan

Angiotensin-l/captopril competitive interaction studies with 46-residues catalytic site 7-11 -107 628

maquettes of angiotensin-I converting enzymes through NMR studies

Tsami Natalia, Galanis Athanassios S„ Spyroulias Georgios A, Pairas George,

Manessi-Zoupa Evy, Cordopatis Paul

The influence of human cystatin C hinge loop LI on its dimerization and 7-11-108 630

oligomerization propensities

Szymanska Aneta, Czaplewska Paulina, Jankowska Elzbieta, Radulska Adrianna,

Wahlbom Maria, Gnibb Anders, LiberekKrzysztof, Rodziewicz-Motowidh Sylwia

14-DHP-lipid forms rod like micellae 7-12-109 632

Liepina Inta, Plotniece Aiva, Czaplewski Cezary, Liwo Adam, PajusteKaiiis, Ose Velta,

Duburs Gurrars

Sell-assembling cyclic peptides for peptide nanotube formation 7-14-110 634

Kato Tamaki, Yoshizaki Mai, Nishio Natsuko, Kuwahara Junko, Nishino Norikazu

Control of duplex formation and columnar self-assembly with heterogeneous amide/ 7-14-111 636

urea mac recyclesFischer Lucile, Decossas Marion, BriandJean-Paul, Didierjean Claude, Guichard Gilles

Site-specific labelling of proteins using an engineered intein 7-17-112 638

Aranko A Sesilja, Iwai Hideo

Fluorescent agonists for the human vasopressin Vlb receptor 7-18-113 640

Gidllon Gilles, Mural Brigitte, Corbani Maithe, Boulay Vera, Stoev Stoytcho,Manning Maurice

DNA-peptide interaction forces on the single molecule level 7-25-114 642

Wollschldger Katrin, Gaus Kalharina, KornigAndre, Eckel Rainer, Wilking Sven David,

Lavas Zsuzsa, Majer Zsuzsa, BeckerAnke, Ros Robert, Anselmetti Dario, Sewald Norbert

Hemoglobin peptides in mammalian tissues: facts or artifacts? 7-27-115 644

Yatskin Oleg, Karelin Andrei, Ivanov Vadim

Photoswitchable DNA bis-intercalators — structure and activity 7-28-116 646

Gaus Katharina, Wollschldger Katrin, Zobel Ansgai; Niefi Anke, KorffGerrit,

Juodaityte Jovita, Kleimann Christoph, Sischka Andy, Anselmetti Dario, SewaldNorbert

Melanocollagen type 1 - structure obtaining and application 7-29-117 648

Pi-zybylski Jozef, Rogala Piotr, Siemaszko-Przybylska Kiystyna

2-Alkyl-2-carboxyazetidines as reverse turns inducers when incorporated at (i+2) 7-29-118 650

position of model peptides

Baeza Jose Luis, Perez de Vega M"Jesus, Gerona-Navarro Guillermo, Infantes Lourdes,

Garcta-Lopez M Teresa, Gonzalez-Muniz Rosario, Martin-Martinez Mercedes

Determining the location of antimicrobial peptides inside lipid bilayers by combined 7-07-119 652

fluorescence spectroscopy and molecular dynamics simulations

Stella Lorenzo, Bocchinfuso Gianfranco, Grande Giacinto, Orioni Barbara, Venanzi

Mariano, Kim Jin-Young, Yoonkyung Park Yoonkyung, Hahm Kyung-Soo, De Zolti Marta,

Formaggio Fernando, Toniolo Claudia, PalleschiAntonio


XLV

Peptides 2008 : chemistry of peptides in life science ... · Azide as aprotecting groupfor lysine...

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