Pag. 1/45 Product: BIO-STARTER A & B · MATERIAL SAFETY DATA SHEET Conforms to regulation...

MATERIAL SAFETY DATA SHEET

Conforms to regulation 1907/2006/EC Printed on: 03/03/2009 Revision date: January 17th, 2016 Revisione: 04 Pag. 1/45

Product: BIO-STARTER A & B

In this file, in order of arrangement, the component:

BIO-STARTER B

BIO-STARTER A


Conforms to regulation 1907/2006/EC Printed on: 05/03/2009 Revision date: January 17th, 2016 Revision No. 04 Page 1/8

Product: BIO-STARTER “B” Section 1. Identification of the substance or mixture and of the Company / Undertaking

1.1. Product identification: Product name: BIO-STARTER “B”

1.2. Relevant identified uses of the substance or mixture and uses advised against:

Description / Uses: Nutritive for heterotrophic bacterial flora, for ornamental aquariums.

1.3. Details of the supplier of the material safety data sheet:

Company name: E’QUO S.R.L. Address: Via Emilio Boni, 19 Locality and State: 59100 - Prato (PO) - ITALIA Phone: +39 0574 166 62 72 Fax: +39 0574 166 62 73

1.4. Emergency Phone Number:

Florence Poison Center: Telephone +39 055 794 7819 (CAV-Careggi Hospital in Florence). Padua Poison Center: Telephone +39 049 827 5078 (University of Padua). Genoa Poison Center: Telephone +39 010 563 6245 (Scientific Institute G. Gaslini). Turin Poison Center : Telephone +39 011/6637637 (SG Baptist Hospital - Molinette of Turin). Pavia Poison Center: Telephone +39 038 224 444 (CAV IRCCS Fondazione Maugeri-Pavia). Rome Poison Center: Telephone +39 06 305 4343 (CAV Policlinico Gemelli-Rome). Rome Poison Center: Telephone +39 06499780 00 (CAV Policlinico Umberto I-Rome). Naples Poison Center: Telephone +39 081 747 2870 (CAV Cardarelli Hospital-Naples). Milan Poison Centre: Telephone +39 02661010 29 (CAV Niguarda Ca 'Granda - Milan) (H-24) Technical Responsible: Mauro Calabrese Teephone +39 0574 166 62 72 available only during office hours e-mail: [email protected] Section 2. Hazards Identification 2.1. Classification of the substance or mixture: 2.1.1 Classification under the Regulation 1272/2008: The preparation is not classified as hazardous according to

the provisions of Regulation (EC) 1272/2008 (CLP) (and subsequent amendments). 2.2. Labeling elements: Danger labeling under the Regulation (EC) 1272/2008 (CLP) and subsequent amendments. Hazard symbols: None Warnings: None Hazard statements: None Precautionary Statements: None



Product: BIO-STARTER “B” 2.3. Other hazards: At the date of drafting of this sheet, the substances in this mixture do not meet the criteria for classification as PBT or vPvB. Section 3. Composition / Information on the ingredients 3.1. Substances: Not applicable 3.2. Mixtures: Aqueous solution based Mono Sodium Glutamate. Section 4. First aid measures 4.1. Description of first aid measures: 4.1.1. In case of inhalation move exposed individual to fresh air. If respiration is difficult, consult your doctor. In case of skin contact, wash thoroughly with water. Take off contaminated clothing. If irritation occurs seek medical attention. In case of contact with eyes, rinse thoroughly with water. See a doctor. If swallowed, seek medical advice. Do not induce vomiting and do not give anything that is not expressly authorized by the doctor. 4.2. Most important symptoms and effects, both acute and delayed: The product is not hazardous to health. 4.3. Indication of any immediate medical attention and special treatment: For the possibility to consult a doctor refer to section 4.1.1. Section 5. Fire-fighting measures 5.1. Extinguishing media: SUITABLE EXTINGUISHING MEDIA: Carbon dioxide, foam, dry chemical. EXTINGUISHING MEDIA NOT SUITABLE: None in particular. 5.2. Special hazards arising from the substance or mixture: In case of fire can be released decomposition products such as Carbon Oxides. Vapors can be irritating and dangerous to health. 5.3. Recommendations for those involved in extinguishing fires: Work always properly protected. Use protective helmet with visor, fireproof clothing, work gloves, a mask with facemask covering, the whole of the self face, or a scuba in the event of large quantities of smoke. Cool by spraying with water the containers to prevent product decomposition and the development of substances potentially hazardous for health. Collect extinguishing water must not be discharged into drains. Dispose of contaminated water used for extinction and the remains of the fire according to applicable regulations.



Product: BIO-STARTER “B” Section 6. Accidental release measures 6.1. Personal precautions, protective equipment and emergency procedures: 6.1.1. For non-emergency personnel: evacuate from the drop zone. Do nothing if not properly educated about what to do. 6.1.2. For emergency responders: Avoid contact with eyes and skin. Ensure good ventilation. Remove people not involved in the operations of intervention. Do not handle damaged containers or leaked product before donning appropriate protective gear. 6.2. Environmental precautions: Prevent product from entering into the drains, surface water, ground water and neighboring areas. 6.3. Methods and materials for containment and cleaning up: 6.3.1. How to contain a spill: Contain the spill with earth, sand or other inert absorbent material. 6.3.2. How to clean a spill: dispose of the contaminated absorbent and then clean up with water. 6.3.3. Information relating to spills and releases: prevent contamination of surface water and soil with suitable means of containment. 6.4. Reference to other sections (see section 8 and 13): The disposal of contaminated material must be made in accordance with the provisions of section 13. Section 7. Handling and storage 7.1. Precautions for safe handling: 7.1.1. Ensure good ventilation / exhaustion at the workplace. 7.1.2. Keep away from heat sources and protected from the sun's rays. Follow general rules of storage of chemicals. 7.2. Conditions for safe storage, including any incompatibilities: a. Keep away from heat, flames, sparks and other sources of ignition. b. Keep container in a cool, well-ventilated place. c. The product is stable under normal conditions of use and storage. Store at room temperature away from sunlight. d. Use original packaging and undamaged. 7.3. Specific end uses: None known. Section 8. Exposure controls/personal protection 8.1. Control parameters: None known. 8.2. Exposure controls:

As the use of adequate technical equipment must always take priority over personal protective equipment, ensure good ventilation in the workplace through effective local aspiration or bad air vent. Operate and handle according to the usual precautionary measures for handling chemicals. Do not eat, drink or smoke while handling it. Wash hands thoroughly with soap and water before meals and take a shower after work shift. 8.2.1. Appropriate engineering: an extraction unit in accordance with good industrial hygiene practice.



Product: BIO-STARTER “B”

8.2.2. Individual protection measures, such as personal protective equipment: 8.2.2.1. Maintain the personal protective equipment as reported in the instruction manual. 8.2.2.2. Eye / face: we recommend using protective airtight goggles (EN 166) Protection of the skin: Hand protection: protective gloves for chemicals in PVC or rubber (ref. Standard EN 374). Other: protective work clothing, work clothes with long sleeves and safety footwear for professional use (ref. Standard EN 344) Respiratory protection: It is advisable to use mask with filter type B, the class (1,2o3) must be chosen according to the limit concentration of use (ref. Standard 14387). In the case were present vapors with particles (aerosols, fumes, mists, etc.) Must be worn type filters are combined (gas and particles). Thermal hazards: combustion products may include carbon oxides and toxic pyrolysis products.

8.2.3. Environmental exposure controls: Depending on the mode of use of the product in various environmental compartments, is recalled to comply with any national or Community provisions to protect the environment. Section 9. Physical and chemical properties 9.1. Information on basic physical and chemical: Physical form: Liquid Color: turquoise/green light Odor: characteristic Odor detection threshold: NA (not available). pH = 8 Melting point or freezing: NA (not available). Boiling Point range: NA (not available). Distillation range: NA (not available). Flash Point: NA (not available). Evaporation Rate: NA (not available). Flammability of solids and gases: NA (not available). Lower explosive limit: NA (not available). Upper limit of flammability: NA (not available). Lower explosive limit: NA (not available). Upper explosive limit: NA (not available). Vapor Pressure: NA (not available). Vapour density: NA (not available). Relative density: NA (not available). Solubility: Soluble in water N-octanol/water partition coefficient: NA (not available). Ignition temperature: NA (not available). Decomposition temperature: 200 °C Viscosity: NA (not available). Explosive properties: NA (not available). Oxidizing properties: NA (not available). 9.2. Other information: VOC (%): 0 %



Product: BIO-STARTER “B” Section 10. Stability and reactivity 10.1. reactivity: Specific information is not available on this product. 10.2. Chemical stability: The mixture is stable under normal conditions of use and storage. 10.3. Possibility of hazardous reactions: Specific information is not available on this product. 10.4. Conditions to avoid: Do not expose to heat. 10.5. Incompatible materials: Oxidizing agents. 10.6. Hazardous decomposition products: Oxides of Sulfur, Oxides of Carbon, Nitrogen Oxides NOx. Section 11. Toxicological information 11.1 Information on toxicological effects: Information on: a. Acute toxicity: Not applicable. b. Corrosion/ irritation: Not applicable. c. Serious eye damage/eye irritation: Not applicable. d. Respiratory or skin sensitization: Not applicable. e. Germ cell mutagenicity: Not applicable. f. Carcinogenicity: Not applicable. g. Reproductive toxicity: Not applicable. h. Specific target organ toxicity (STOT): Not available. i. Aspiration hazard: Not applicable. IDENTIFICATION LD50 OR LC50 Mono Sodium Glutamate LD50 oral rat: 2000 mg/kg LD50 cute rat > 2000 mg/kg Information on likely routes of exposure: the likely routes of exposure include inhalation (for mists and vapors) and skin, much less likely, if swallowed. Symptoms related to the physical, chemical and toxicological characteristics: See Section 4.2 of this safety data sheet. Interactive effects: Not known



Product: BIO-STARTER “B” Other information: None known. Section 12. Ecological information The product is not considered dangerous for the environment and is not harmful to aquatic organisms. 12.1 Toxicity: tossicità acquatica: Mono Sodium Glutamate LC50 (96H) Cyprinus Carpio> 100 mg/L EC50 (48H) Daphnia Magna:> 100 mg/L EC50 (72H) Alga Pseudokirchneriella Subcapitata:> 2 mg/L 12.2 Persistence and degradability: Readily biodegradable. 12.3 Bioaccumulative potential: Slightly bioaccumulable. 12.4 Mobility in soil: Not known. 12.5 Results of PBT and vPvB assessment: his product is not, or does not contain a substance classified as PBT or vPvB. 12.6 Other adverse effects: Specific information is not available on this product.

Section 13. Disposal considerations 13.1. Waste treatment methods: a. Containers and methods for treatment: Uncontaminated packaging can be reused, while those not reclaimed must be disposed of as the mixture. b. Chemical / physical properties that may affect waste treatment: The product is stable under normal conditions. c. Disposal through waste water: Waste should not be disposed of by the release in exhaust ducts. d. Any special precautions during treatment: None in particular.



Product: BIO-STARTER “B” Section 14. Transport information The product is not classified as dangerous under current provisions governing the transport of dangerous goods by road (ADR), by Rail (RID), by sea (IMDG Code) and by air (IATA). Section 15. Regulatory information 15.1. Standards and legislation on health, safety and environment specific for the substance or mixture:

Seveso category. None. Restrictions relating to the product or contained substances pursuant to Annex XVII to Regulation (EC) 1907/2006: None. Substances in Candidate List (Art. 59 REACH): None. Substances subject to authorization (Annex XIV REACH): None. 15.2. Chemical safety assessment: The chemical risk of substance, has not been processed. Classes VOC (Ref. Tab. D Alleg. The Legislative Decree 152/2006 Part V): 0 % Section 16. Other information a. Indicate revision of the card and all points audited: This edition of this MSDS, replaces previous versions in section 16 for adaptation to Regulation 830/2015 of the European Parliament. b. An explanation of acronyms used with legend: ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road. ASTM: ASTM American Society for Testing and Materials (ASTM). ATE: Acute toxicity estimate. EINECS: European Inventory of Existing Commercial Chemical Substances. EC50: Effective Concentration 50 %. LC50: Lethal Concentration 50 %. IC50: Inhibitor Concentration 50 %. NOEL: No Observed Effect Level. NOEC: No Observed Effect Concentration. LOEC: Lowest Observed Effect Concentration. DNEL: Derived No Effect Level. DMEL: Derived Minimum Effect Level. CLP: Classification, Labelling and Packaging. LD(0/50/10): Lethal Dose 0/50/100. CSR: Chemical Safety Report. IATA: International Air Transport Association. ICAO: International Civil Aviation Organization. Code IMDG: International Maritime Dangerous Goods code. PBT: Persistent, bioaccumulative and toxic. vPvB: Very persistent very bioaccumulative. RID: Regulation concerning the international transport of dangerous goods by train. PNEC: Predicted No effect Concentration. PNOS: Particulates not Otherwise specified.



Product: BIO-STARTER “B” BOD: Biochemical Oxtgen Demand. COD: Chemical Oxygen Demand. BCF: BioConcentration factor. STEL: Short term exposure limit. TLV: Threshold limit value. TWA: Time Weighted Average. EU: European Union. VOC: Volatile organic compounds EmS: Emergency Schedule. GHS: Globally Harmonized System of Classification and Labelling of Chemicals CAS NUMBER: Chemical Abstract Service Number. IMO: International Maritime Organization. INDEX NUMBER: Identification number in Annex VI to the CLP ECHA: European chemicals agency.

b. Key literature references and sources of data: see previous point. 1. Directive 1999/45/EC and following amendments. 2. Directive 67/548/EEC and following amendments and adjustments (XXIX technical adjustment). 3. Regulation (EC) 1907/2006 (REACH) of the European Parliament (REACH). 4. Regulation (EC) 1272/2008 (CLP) of the European Parliament and following amendments and adjustments (CLP). 5. Regulation (EC) 790/2009 (I Atp. CLP) of the European Parliament (I ATP CLP). 6. Regulation (EC) 2015/830 of the European Parliament. 7. Regulation (EC) 286/2011 of the European Parliament (II ATP CLP). 8. Regulation (EC) 618/2012 of the European Parliament (III ATP CLP). 9. The Merck Index. 10th Edition. 10. Handling Chemical Safety. 11. Niosh – Registry of Toxic Effects of Chemical Substances. 12. INRS – Fiche Toxicologique (toxicological sheet). 13. Patty – Industrial Hygiene and Toxicology. 14. N.I. Sax-Dangerous properties of Industrial Materials-7, 1989 edition.

c. Details of any adequate information for workers: Operate in accordance with good industrial hygiene practices, adopting preventive and protective measures appropriate to the nature of the product as given in this material safety data sheet.

d. List phrases H: None

Codes of class and hazard category: None Note for users: The information in this sheet are based on knowledge available at the date of the last version. Users must verify the suitability and completeness of information in relation to the specific use of the product. It should not be construed as a guarantee on any specific product property. Since the use of this product is not under our direct control, users must, under their own responsibility, laws and regulations on hygiene and safety. Do not assume responsibility for improper use. Issuing MSDS: E’QUO S.r.l. For more information contact: Mauro Calabrese



Product: BIO-STARTER “A” Section 1. Identification of the substance or mixture and of the Company / Undertaking

1.1. Product identification: Product name: BIO-STARTER “A “

1.2. Relevant identified uses of the substance or mixture and uses advised against:

Description / Uses: Nutrient for heterotrophic bacterial flora, for ornamental aquarium.

1.3. Details of the supplier of the material safety data sheet:

Company name: E’QUO S.R.L. Address: Via Emilio Boni, 19 Locality and State: 59100 - Prato (PO) - ITALIA Phone: +39 0574 166 62 72 Fax: +39 0574 166 62 73

1.4. Emergency Phone Number:

Florence Poison Center: Telephone +39 055 794 7819 (CAV-Careggi Hospital in Florence). Padua Poison Center: Telephone +39 049 827 5078 (University of Padua). Genoa Poison Center: Telephone +39 010 563 6245 (Scientific Institute G. Gaslini). Turin Poison Center : Telephone +39 011/6637637 (SG Baptist Hospital - Molinette of Turin). Pavia Poison Center: Telephone +39 038 224 444 (CAV IRCCS Fondazione Maugeri-Pavia). Rome Poison Center: Telephone +39 06 305 4343 (CAV Policlinico Gemelli-Rome). Rome Poison Center: Telephone +39 06499780 00 (CAV Policlinico Umberto I-Rome). Naples Poison Center: Telephone +39 081 747 2870 (CAV Cardarelli Hospital-Naples). Milan Poison Centre: Telephone +39 02661010 29 (CAV Niguarda Ca 'Granda - Milan) (H-24) Technical Responsible: Mauro Calabrese Teephone +39 0574 166 62 72 available only during office hours e-mail: [email protected] Section 2. Hazards Identification 2.1. Classification of the substance or mixture: 2.1.1 Classification under the Regulation 1272/2008: The preparation is classified as hazardous according to the

provisions of Regulation (EC) 1272/2008 (CLP) (and subsequent amendments). Skin Corr. 1B H314 Eye Dam 1 H318



Product: BIO-STARTER “A” 2.2. Labeling elements: Danger labeling under the Regulation (EC) 1272/2008 (CLP) and subsequent amendments.

Hazard symbols: GHS05

Warnings: DANGER

Hazard statements: H314 CAUSES SEVERE SKIN BURNS AND EYE DAMAGE

Precautionary Statements: P210 Keep away from heat/sparks/open flames/hot surfaces. No smoking P233 Keep container tightly closed P280 WEAR PROTECTIVE GLOVES/PROTECTIVE CLOTHING/EYE PROTECTION/FACE PROTECTION.

P304+P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.

P310 Immediately call a POISON CENTER or doctor/physician.

2.3. Other hazards: At the date of drafting of this sheet, the substances in this mixture do not meet the criteria for classification as PBT or vPvB. Section 3. Composition / Information on the ingredients 3.1. Substances: Not applicable 3.2. Mixtures:

Denomination

Concentration (%)

Classification 1272/2008/CE

Acetic Acid 15<C<35 H226 Flam. Liq.3 N° Cas: 64-19-7 H314 Skin Corr.1A N° CE: 200-58-7 N° Index: 607-002-00-6 N° Reg.: 01-2119475328-30-XXXX

The full text of hazard (H) is given in section 16 of the MSDS.



Product: BIO-STARTER “A” Section 4. First aid measures 4.1. Description of first aid measures: 4.1.1. In case of inhalation move exposed individual to fresh air. If respiration is difficult, consult your doctor. In case of skin contact, wash thoroughly with water. Take off contaminated clothing. If irritation occurs seek medical attention. In case of contact with eyes, rinse immediately with plenty of water for at least 15 minutes. SEEK MEDICAL ATTENTION IMMEDIATELY. If swallowed, seek medical advice. Do not induce vomiting and do not give anything that is not expressly authorized by the doctor. 4.2. Most important symptoms and effects, both acute and delayed: The product is corrosive and causes severe burns and blistering of the skin, which can arise even after exposure. Burns are very stinging and pain. Contact with eyes causes serious injuries and may cause corneal opacity, iris lesions, irreversible eye coloration. 4.3. Indication of any immediate medical attention and special treatment: For the possibility to consult a doctor refer to section 4.1.1. Section 5. Fire-fighting measures 5.1. Extinguishing media: SUITABLE EXTINGUISHING MEDIA: Carbon dioxide, foam, dry chemical. EXTINGUISHING MEDIA NOT SUITABLE: None in particular. 5.2. Special hazards arising from the substance or mixture: In case of fire can be released decomposition products such as Carbon Oxides. Vapors can be irritating and dangerous to health. 5.3. Recommendations for those involved in extinguishing fires: Work always properly protected. Use protective helmet with visor, fireproof clothing, work gloves, a mask with facemask covering, the whole of the self face, or a scuba in the event of large quantities of smoke. Cool by spraying with water the containers to prevent product decomposition and the development of substances potentially hazardous for health. Collect extinguishing water must not be discharged into drains. Dispose of contaminated water used for extinction and the remains of the fire according to applicable regulations. Section 6. Accidental release measures 6.1. Personal precautions, protective equipment and emergency procedures: 6.1.1. For non-emergency personnel: evacuate from the drop zone. Do nothing if not properly educated about what to do. 6.1.2. For emergency responders: Avoid contact with eyes and skin. Ensure good ventilation. Remove people not involved in the operations of intervention. Do not handle damaged containers or leaked product before donning appropriate protective gear. 6.2. Environmental precautions: Prevent product from entering into the drains, surface water, ground water and neighboring areas.



Product: BIO-STARTER “A” 6.3. Methods and materials for containment and cleaning up: 6.3.1. How to contain a spill: Contain the spill with earth, sand or other inert absorbent material. 6.3.2. How to clean a spill: dispose of the contaminated absorbent and then clean up with water. 6.3.3. Information relating to spills and releases: prevent contamination of surface water and soil with suitable means of containment. 6.4. Reference to other sections (see section 8 and 13): The disposal of contaminated material must be made in accordance with the provisions of section 13. Section 7. Handling and storage 7.1. Precautions for safe handling: 7.1.1. Ensure good ventilation / exhaustion at the workplace. 7.1.2. Keep away from heat sources and protected from the sun's rays. Follow general rules of storage of chemicals. 7.2. Conditions for safe storage, including any incompatibilities: a. Keep away from heat, flames, sparks and other sources of ignition. b. Keep container in a cool, well-ventilated place. c. The product is stable under normal conditions of use and storage. Store at room temperature away from sunlight. d. Use original packaging and undamaged. 7.3. Specific end uses: None known. Section 8. Exposure controls/personal protection 8.1. Control parameters:

Descrition Type State TWA/8h STEL/15 min mg/m3 ppm mg/m3 ppm

Acetic Acid ACGIH USA 25 10 37 15

Other parameters: ACETIC ACID: Specification: DNEL (EC) Parameter: Local Effects_Short-term_Inhalation_Workers Value: 25 mg / m3 Released: Specification: DNEL (EC) Parameter: Local Effects_Long-term _Inhalation_Workers Value: 25 mg / m3 Released:



Product: BIO-STARTER “A” Specification: DNEL (EC) Parameter: Local Effects_Short-term_Inhalation_Population Value: 25 mg / m3 Released: Specification: DNEL (EC) Parameter: Local Effects_ Long-term _Inhalation_Population Value: 25 mg / m3 Released: Specification: PNEC STP (EC) Value: 85 mg / l Released: Specification: PNEC (EC) Parameter: Sediment (seawater) Value: 1,136 mg / kg Released: Specification: PNEC (EC) Parameter: Soil Value: 0.47 mg / kg Released: Specification: PNEC (EC) Parameter: Fresh water Value: 3,058 mg / l Released: Specification: PNEC (EC) Parameter: Aquamarine Value: 0.3058 mg / l Released: Specification: PNEC (EC) Parameter: Emission occasional Value: 30,58 mg / l Released: Specification: PNEC (EC) Parameter: Sediment (freshwater) Value: 11,36 mg / kg Released: Specification: TWA (EC) Value: 10 ppm / 25 mg / m3 Released: 29/05/1991 8.2. Exposure controls:

As the use of adequate technical equipment must always take priority over personal protective equipment, ensure good ventilation in the workplace through effective local aspiration or bad air vent. Operate and handle according to the usual precautionary measures for handling chemicals. Do not eat, drink or smoke while handling it. Wash hands thoroughly with soap and water before meals and take a shower after work shift.



Product: BIO-STARTER “A”

8.2.1. Appropriate engineering: an extraction unit in accordance with good industrial hygiene practice. 8.2.2. Individual protection measures, such as personal protective equipment: 8.2.2.1. Maintain the personal protective equipment as reported in the instruction manual. 8.2.2.2. Eye / face: we recommend using protective airtight goggles (EN 166) Protection of the skin: Hand protection: protective gloves for chemicals in PVC or rubber (ref. Standard EN 374). Other: protective work clothing, work clothes with long sleeves and safety footwear for professional use (ref. Standard EN 344) Respiratory protection: It is advisable to use mask with filter type B, the class (1,2o3) must be chosen according to the limit concentration of use (ref. Standard 14387). In the case were present vapors with particles (aerosols, fumes, mists, etc.) Must be worn type filters are combined (gas and particles). Thermal hazards: combustion products may include carbon oxides and toxic pyrolysis products.

8.2.3. Environmental exposure controls: Depending on the mode of use of the product in various environmental compartments, is recalled to comply with any national or Community provisions to protect the environment. Section 9. Physical and chemical properties 9.1. Information on basic physical and chemical: Physical form: Liquid Color: Pink Violet Odor: Very pungent Odor detection threshold: NA (not available). pH = 2 Melting point or freezing: > 65 °C Boiling Point range: NA (not available). Distillation range: NA (not available). Flash Point: NA (not available). Evaporation Rate: NA (not available). Flammability of solids and gases: NA (not available). Lower explosive limit: NA (not available). Upper limit of flammability: NA (not available). Lower explosive limit: NA (not available). Upper explosive limit: NA (not available). Vapor Pressure: NA (not available). Vapour density: NA (not available). Relative density: NA (not available). Solubility: Soluble in water: 1,184 g/l N-octanol/water partition coefficient: NA (not available). Ignition temperature: NA (not available). Decomposition NA (not available). Viscosity: NA (not available). Explosive properties: Not explosive Oxidizing properties: Not-oxidizing 9.2. Other information: VOC (%): c.a. 15-30%



Product: BIO-STARTER “A” Section 10. Stability and reactivity 10.1. reactivity: The product is stable in normal conditions of use and storage. 10.2. Chemical stability: The mixture is stable under normal conditions of use and storage. 10.3. Possibility of hazardous reactions: Acetic Acid: risk of explosion on contact with: Chromium Oxide (VI), Potassium Permanganate, Sodium Peroxide, Perchloric Acid, Phosphorus Chloride, Hydrogen Peroxide. It can react dangerously with: Alcohols, Bromine Pentafluoride, Chlorosulphuric Acid, Dichromate-Sulfuric Acid, Diamino Ethane, Potassium Hydroxide, strong bases, Sodium Hydroxide, strong oxidizing agents, Nitric Acid, Ammonium Nitrate, Potassium Tert-butoxide. Forms explosive mixtures with air. 10.4. Conditions to avoid: In case of fire, the product may undergo thermal decomposition releasing dangerous gas / vapors Acetic Acid: avoid exposure to sources of heat and open flames. 10.5. Incompatible materials: Acetic Acid: carbonates, hydroxides, many oxides. Oxidizing and bases. 10.6. Hazardous decomposition products: When heated or in case of fire can release gases and vapors which are dangerous to health. Section 11. Toxicological information 11.1 Information on toxicological effects: Information on: a. Acute toxicity: Not applicable. b. Corrosion/ irritation: Severe skin burns. c. Serious eye damage/eye irritation: Serious eye damage. d. Respiratory or skin sensitization: Not applicable. e. Germ cell mutagenicity: Not applicable. f. Carcinogenicity: Not applicable. g. Reproductive toxicity: Not applicable. h. Specific target organ toxicity (STOT): Not available. i. Aspiration hazard: Not applicable. IDENTIFICATION LD50 OR LC50 Acetic Acid LD50 oral rat> 3310 mg/kg LC50 Dermal rabbit: 1060 mg/kg LD50 Inhalation rat> 11.4 mg/l 4H



Product: BIO-STARTER “A” Information on likely routes of exposure: the likely routes of exposure include inhalation (for mists and vapors) and skin, much less likely, if swallowed. Symptoms related to the physical, chemical and toxicological characteristics: see Section 4.2 of this MSDS. Interactive effects: Not known Other information: None known Section 12. Ecological information. The product is not considered dangerous for the environment and is not harmful to aquatic organisms. 12.1 Toxicity: Acetic Acid LC50 (96H) Freshwater> 300.82 mg/L EC50 (48H) Daphnia Magna> 300.82 mg/L NOEC Daphnia Magna: 31.4 mg/L 12.2 Persistence and degradability: Not known. 12.3 Bioaccumulative potential: Minimum. 12.4 Mobility in soil: Not known. 12.5 Results of PBT and vPvB assessment: Not applicable. 12.6 Other adverse effects: Not known.

Section 13. Disposal considerations. 13.1. Waste treatment methods: a. Containers and methods for treatment: Uncontaminated packaging can be reused, while those not reclaimed must be disposed of as the mixture. b. Chemical / physical properties that may affect waste treatment: The product is stable under normal conditions. c. Disposal through waste water: Waste should not be disposed of by the release in exhaust ducts. d. Any special precautions during treatment: None in particular.



Product: BIO-STARTER “A” Section 14. Transport information

RID/ADR: N° ONU 2790 Class: 8 Denomination: Packing Group: III Proper shipping name: Acetic Acid solution containing more than 10% but less than 50% acid by mass Sea transport (IMDG Code): Aluminium Chloride solution N° ONU 2790 Class: 8 Packing Group: III EmS: F-A,S-B Marine pollulant NO Proper shipping name: Air transport (ICAO-IATA): N° ONU 2790 Class: 8 Packing Group: III Label 8

Section 15. Regulatory information 15.1. Standards and legislation on health, safety and environment specific for the substance or mixture:

Seveso category. None. Restrictions relating to the product or contained substances pursuant to Annex XVII to Regulation (EC) 1907/2006: None. Substances in Candidate List (Art. 59 REACH): None. Substances subject to authorization (Annex XIV REACH): None. 15.2. Chemical safety assessment: Has been developed the chemical risk assessment of the substance. Has been elaborated an evaluation for the substance contained in the mixture. Classes VOC (Ref. Tab. D Alleg. The Legislative Decree 152/2006 Part V): c.a. 15-30% Section 16. Other information a. Indicate revision of the card and all points audited: This edition of this MSDS, replaces previous versions in section 16 for adaptation to Regulation 830/2015 of the European Parliament.

b. An explanation of acronyms used with legend: ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road. ASTM: ASTM American Society for Testing and Materials (ASTM).



Product: BIO-STARTER “A” ATE: Acute toxicity estimate. EINECS: European Inventory of Existing Commercial Chemical Substances. EC50: Effective Concentration 50 %. LC50: Lethal Concentration 50 %. IC50: Inhibitor Concentration 50 %. NOEL: No Observed Effect Level. NOEC: No Observed Effect Concentration. LOEC: Lowest Observed Effect Concentration. DNEL: Derived No Effect Level. DMEL: Derived Minimum Effect Level. CLP: Classification, Labelling and Packaging. LD(0/50/10): Lethal Dose 0/50/100. CSR: Chemical Safety Report. IATA: International Air Transport Association. ICAO: International Civil Aviation Organization. Code IMDG: International Maritime Dangerous Goods code. PBT: Persistent, bioaccumulative and toxic. vPvB: Very persistent very bioaccumulative. RID: Regulation concerning the international transport of dangerous goods by train. PNEC: Predicted No effect Concentration. PNOS: Particulates not Otherwise specified. BOD: Biochemical Oxtgen Demand. COD: Chemical Oxygen Demand. BCF: BioConcentration factor. STEL: Short term exposure limit. TLV: Threshold limit value. TWA: Time Weighted Average. EU: European Union. VOC: Volatile organic compounds EmS: Emergency Schedule. GHS: Globally Harmonized System of Classification and Labelling of Chemicals CAS NUMBER: Chemical Abstract Service Number. IMO: International Maritime Organization. INDEX NUMBER: Identification number in Annex VI to the CLP ECHA: European chemicals agency.

b. Key literature references and sources of data: see previous point. 1. Directive 1999/45/EC and following amendments. 2. Directive 67/548/EEC and following amendments and adjustments (XXIX technical adjustment). 3. Regulation (EC) 1907/2006 (REACH) of the European Parliament (REACH). 4. Regulation (EC) 1272/2008 (CLP) of the European Parliament and following amendments and adjustments (CLP). 5. Regulation (EC) 790/2009 (I Atp. CLP) of the European Parliament (I ATP CLP). 6. Regulation (EC) 2015/830 of the European Parliament. 7. Regulation (EC) 286/2011 of the European Parliament (II ATP CLP). 8. Regulation (EC) 618/2012 of the European Parliament (III ATP CLP). 9. The Merck Index. 10th Edition. 10. Handling Chemical Safety. 11. Niosh – Registry of Toxic Effects of Chemical Substances. 12. INRS – Fiche Toxicologique (toxicological sheet). 13. Patty – Industrial Hygiene and Toxicology. 14. N.I. Sax-Dangerous properties of Industrial Materials-7, 1989 edition.



Product: BIO-STARTER “A”

c. Details of any adequate information for workers: Operate in accordance with good industrial hygiene practices, adopting preventive and protective measures appropriate to the nature of the product as given in this material safety data sheet.

d. For mixtures, explanation of the methods of grading 1272/2008: Method of calculation: H318, H314.

e. List phrases H: H226 FLAMMABLE LIQUID AND VAPOUR H314 CAUSES SEVERE SKIN BURNS AND EYE DAMAGE

Codes of class and hazard category: Flam.Liq.3 Flammable liquid, category 3 Skin Corr.1A Skin corrosion Category 1A Skin Corr.1B Skin corrosion Category 1B Note for users: The information in this sheet are based on knowledge available at the date of the last version. Users must verify the suitability and completeness of information in relation to the specific use of the product. It should not be construed as a guarantee on any specific product property. Since the use of this product is not under our direct control, users must, under their own responsibility, laws and regulations on hygiene and safety. Do not assume responsibility for improper use. Issuing MSDS: E’QUO S.r.l. For more information contact: Mauro Calabrese

SAFETY DATA SHEET according to Regulation (EC) No. 1907/2006

acetic acid...% Version 1.0

Revision Date 14.06.2013

Short title

Distribution of substance

Formulation & (re)packing of

substances and mixtures

Use in Cleaning Agents

Use in Cleaning

Agents

Use in laboratories Use in laboratories

Use as water treatment chemicals

Use in Oil and Gas field drilling and

production operations PA100049_001

Sector of Use (SU)

1, 2a, 2b, 4, 5, 6a, 6b,

7

NA

5

NA

10 NA

8, 9

10

Environm ental

Release Category

(ERC)

1, 2

2

4

8a, 8d

4 8a

1

1

No.

1 2

3 4 5 6

7

8

Product Category

(PC)

NA

NA

NA

NA

NA NA

NA

NA

11/35

Print Date 14.06.2013

Article Category Specified

(AC)

NA ES8

NA ES2319

NA ES2409

NA ES2411

NA ES2466 NA ES2470

NA ES2481

NA ES2472

EN

Main User

Group (SU)

3

3

3

22

3 22

3

3

Process Category (PROC)

1, 2, 3, 4, 8a, 8b, 9,

15 1, 2, 3, 4, 5, 8a, 8b, 9, 14, 15

2, 3, 4, 7, 8a, 8b, 10, 13

1, 2, 3, 4, 8a, 8b,

10, 11, 13 10, 15 10, 15

1, 2, 3, 4, 8a, 8b, 15

1, 2, 3, 4, 8a, 8b, 15


acetic acid...% Version 1.0 Print Date 14.06.2013

Revision Date 14.06.2013 1. Short title of Exposure Scenario 1: Distribution of substance

SU 3: Industrial uses: Uses of substances as such or in preparations at industrial sites SU1: Agriculture, forestry, fishery SU2a: Mining (without offshore industries) SU2b: Offshore industries SU4: Manufacture of food products SU5: Manufacture of textiles, leather, fur SU6a: Manufacture of wood and wood products SU6b: Manufacture of pulp, paper and paper products SU7: Printing and reproduction of recorded media PROC1: Use in closed process, no likelihood of exposure PROC2: Use in closed, continuous process with occasional controlled exposure PROC3: Use in closed batch process (synthesis or formulation) PROC4: Use in batch and other process (synthesis) where opportunity for exposure arises PROC8a: Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at non-dedicated facilities PROC8b: Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at dedicated facilities PROC9: Transfer of substance or preparation into small containers (dedicated filling line, including weighing) PROC15: Use as laboratory reagent ERC1: ERC2:

2.1 Contributing scenario controlling environmental exposure for: ERC1, ERC2 No exposure assessment presented for the environment., In the chemical safety assessment performed according to Article 14(3) in connection with Annex I section 3 (Environmental Hazard Assessment) and section 4 (PBT/vPvB Assessment) no hazard was Identified., Therefore according on REACH Annex I (5.0) an exposure estimation and risk characterisation is not necessary 2.2 Contributing scenario controlling worker exposure for: PROC1, PROC2, PROC3, PROC4,

PROC8a, PROC8b , PROC9 , PROC15 Physical Form (at time of use) Vapour pressure Assumes use at not more than 20°C above ambient temp erature.

Covers daily exposures up to 8 hours (unless stated differently).

Batch process Handle substance within a closed system. with sample collection provide a good standard of general ventilation (not

12/35 EN

Main User Groups Sectors of end-use Process categories

Environmental Release Categories

Manufacture of substances Formulation of preparations

liquid

> 100 hPa Product characteristics Frequency and duration of use Technical conditions and measures to control dispersion

PA100049_001


acetic acid...% Print Date 14.06.2013

less than 3 to 5 air changes per hour). Avoid carrying out operation for more than 1 hour.(PROC4) Provide extract ventilation to points where emissions occur.(PROC4) Sample via a closed loop or other system to avoid exposure.(PROC8b) Handle in a fume cupboard or under extract ventilation.(PROC15) Clear lines prior to de-coupling. Provide extract ventilation to points where emissions occur.(PROC8b) Provide extract ventilation to points where emissions occur.(PROC8b) Provide extract ventilation to points where emissions occur.(PROC9) Drain down system prior to equipment break-in or maintenance.(PROC8a, PROC8b) Store substance within a closed system. Locate bulk storage outdoors. or provide a good standard of general ventilation (not less than 3 to 5 air changes per hour).(PROC2) or If above technical/organisational control measures are not feasible, then adopt following PPE: Wear a respirator conforming to EN140 with Type A filter or better. Wear suitable gloves tested to EN374.(PROC8b) If above technical/organisational control measures are not feasible, then adopt following PPE: Wear a respirator conforming to EN140 with Type A filter or better. Wear suitable gloves tested to EN374.(PROC8b) Wear suitable gloves tested to EN374.(PROC8a, PROC8b)

Workers

ECETOC TRA Version 2 with modifications has been used. When the recommended risk management measures (RMMs) and operational conditions (OCs) are observed, exposures are not expected to exceed the predicted PNECs and the resulting risk characterisation ratios are expected to be less than 1. 4. Guidance to Downstream User to evaluate whether he works inside the boundaries set by the

PA100049_001 13/35 EN

Equipment cleaning and maintenance

3. Exposure estimation and reference to its source

Version 1.0


from source towards the worker

Conditions and measures related to personal protection, hygiene and health evaluation

General exposures (closed systems)

Process sampling Laboratory activities Bulk transfers (closed systems)

Bulk transfers (open systems) Drum and small package filling Equipment cleaning and maintenance Storage with occasional controlled exposure Bulk transfers (closed systems)

Bulk transfers (open systems)




Exposure Scenario

Guidance is based on assumed operating conditions which may not be applicable to all sites; thus, scaling may be necessary to define appropriate site-specific risk management measures. Estimated exposures are not expected to exceed PNEC when the identified Risk Management Measures / Operational Conditions are adopted, as indicated in Section 2 Predicted exposures are not expected to exceed the DN(M)EL when the Risk Management Measures/Operational Conditions outlined in Section 2 are implemented. Where other Risk Management Measures/Operational Conditions are adopted, then users should ensure that risks are managed to at least equivalent levels.

Additional good practice advice beyond the REACH Chemical Safety Assessment

Assumes a good basic standard of occupational hygiene is implemented. PA100049_001 14/35 EN



Revision Date 14.06.2013 1. Short title of Exposure Scenario 2: Formulation & (re)packing of substances and mixtures

SU 3: Industrial uses: Uses of substances as such or in preparations at industrial sites PROC1: Use in closed process, no likelihood of exposure PROC2: Use in closed, continuous process with occasional controlled exposure PROC3: Use in closed batch process (synthesis or formulation) PROC4: Use in batch and other process (synthesis) where opportunity for exposure arises PROC5: Mixing or blending in batch processes for formulation of preparations and articles (multistage and/or significant contact) PROC8a: Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at non-dedicated facilities PROC8b: Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at dedicated facilities PROC9: Transfer of substance or preparation into small containers (dedicated filling line, including weighing) PROC14: Production of preparations or articles by tabletting, compression, extrusion, pelettisation PROC15: Use as laboratory reagent

Formulation of preparations

2.1 Contributing scenario controlling environmental exposure for: ERC2 In the chemical safety assessment performed according to Article 14(3) in connection with Annex I section 3 (Environmental Hazard Assessment) and section 4 (PBT/vPvB Assessment) no hazard was Identified., Therefore according on REACH Annex I (5.0) an exposure estimation and risk characterisation is not necessary 2.2 Contributing scenario controlling worker exposure for: PROC1, PROC2, PROC3, PROC4,

PROC5, PROC8a , PROC8b , PROC9 , PROC14 , PROC15

Covers percentage substance in the product up to 100 % (unless stated differently).

liquid

> 100 hPa Assumes use at not more than 20°C above ambient temp erature.


Assumes a good basic standard of occupational hygiene is implemented.

General exposures Handle substance within a closed system.(PROC1, (closed systems) PROC2)

15/35 EN

Main User Groups Process categories


ERC2:

Concentration of the Substance in Mixture/Article Physical Form (at time of use) Vapour pressure

Product characteristics

Frequency and duration of use Other operational conditions affecting workers exposure Technical conditions and measures to control dispersion

PA100049_001



Handle substance within a closed system. provide a good standard of general ventilation (not less than 3 to 5 air changes per hour).(PROC2)

Handle substance within a closed system. Provide extract ventilation to points where emissions occur.(PROC3)

Provide extract ventilation to points where emissions occur.(PROC4)

Ensure material transfers are under containment or extract ventilation. Avoid carrying out operation for more than 1 hour.(PROC3) Sample via a closed loop or other system to avoid exposure.(PROC8b) Handle in a fume cupboard or under extract ventilation.(PROC15) Ensure material transfers are under containment or extract ventilation.(PROC4, PROC8a, PROC8b)

Provide extract ventilation to points where emissions occur.(PROC4, PROC5)

Provide extract ventilation to points where emissions occur.(PROC8a)

Provide extract ventilation to points where emissions occur.(PROC3, PROC8a, PROC8b, PROC9)


Ensure material transfers are under containment or extract ventilation.(PROC9) Drain down system prior to equipment break-in or maintenance.(PROC8a, PROC8b) Locate bulk storage outdoors. or

EN

General exposures (closed systems) with sample collection with occasional controlled exposure General exposures (closed systems) Use in contained batch processes General exposures (open systems) Batch process with sample collection with potential for aerosol generation Batch processes at elevated temperatures

Process sampling Laboratory activities Bulk transfers

Mixing operations (open systems) with potential for aerosol generation Manual Transfer from/pouring from containers Drum/batch transfers Production of preparations or articles by tabletting, compression, extrusion, pelettisation Drum and small package filling Equipment cleaning and maintenance Storage Product sampling

16/35

Version 1.0


from source towards the worker PA100049_001




provide a good standard of general ventilation (not less than 3 to 5 air changes per hour).(PROC1, PROC2, PROC8b)

Conditions and measures related Equipment cleaning and Wear suitable gloves tested to EN374.(PROC8a, to personal protection, hygiene maintenance PROC8b) and health evaluation


Workers

When the recommended risk management measures (RMMs) and operational conditions (OCs) are observed, exposures are not expected to exceed the predicted PNECs and the resulting risk characterisation ratios are expected to be less than 1. 4. Guidance to Downstream User to evaluate whether he works inside the boundaries set by the

Exposure Scenario


PA100049_001 17/35 EN



Revision Date 14.06.2013 1. Short title of Exposure Scenario 3: Use in Cleaning Agents

SU 3: Industrial uses: Uses of substances as such or in preparations at industrial sites SU5: Manufacture of textiles, leather, fur PROC2: Use in closed, continuous process with occasional controlled exposure PROC3: Use in closed batch process (synthesis or formulation) PROC4: Use in batch and other process (synthesis) where opportunity for exposure arises PROC7: Industrial spraying PROC8a: Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at non-dedicated facilities PROC8b: Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at dedicated facilities PROC10: Roller application or brushing PROC13: Treatment of articles by dipping and pouring

Industrial use of processing aids in processes and products, not becoming articles


PROC8a, PROC8b , PROC10 , PROC13


liquid

> 100 hPa


Assumes use at not more than 20°C above ambient temp erature, unless stated differently., Assumes a good basic standard of occupational hygiene is implemented. Limit the substance content in the mixture to 5 %.(PROC7, PROC10)

18/35 EN


Frequency and duration of use Other operational conditions affecting workers exposure PA100049_001

ERC4: part of


Main User Groups

Sectors of end-use Process categories Environmental Release Categories



Ensure material transfers are under containment or extract ventilation.(PROC8a, PROC8b) provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). Avoid carrying out operation for more than 1 hour.(PROC8a, PROC8b) provide a good standard of general ventilation (not less than 3 to 5 air changes per hour).(PROC2, PROC4)

Ensure material transfers are under containment or extract ventilation.(PROC8b)

Ensure material transfers are under containment or extract ventilation. Avoid carrying out operation for more than 4 hours.(PROC4) Provide extract ventilation to points where emissions occur.(PROC13) provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). Avoid carrying out operation for more than 4 hours.(PROC10) provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). or Ensure operation is undertaken outdoors. Avoid carrying out operation for more than 1 hour.(PROC7) provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). or Ensure operation is undertaken outdoors. Avoid carrying out operation for more than 4 hours.(PROC10) Drain down system prior to equipment break-in or maintenance.(PROC8a, PROC8b) Locate bulk storage outdoors. or provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). Wear suitable gloves tested to EN374.(PROC8a, PROC8b)

EN

Bulk transfers

Automated process with (semi) closed systems Drum/batch transfers Use in contained systems Application of cleaning products in closed systems Filling / preparation of equipment from drums or containers Dedicated facility Use in contained systems Treatment by heating Degreasing small objects in cleaning station Cleaning with low- pressure washers Cleaning with high pressure washers Manual Surfaces cleaning No spraying Equipment cleaning and maintenance

Storage with occasional controlled exposure

Equipment cleaning and maintenance


PA100049_001 19/35

Version 1.0


Technical conditions and measures to control dispersion from source towards the worker





Workers


Exposure Scenario


PA100049_001 20/35 EN



Revision Date 14.06.2013 1. Short title of Exposure Scenario 4: Use in Cleaning Agents

SU 22: Professional uses: Public domain (administration, education, entertainment, services, craftsmen) PROC1: Use in closed process, no likelihood of exposure PROC2: Use in closed, continuous process with occasional controlled exposure PROC3: Use in closed batch process (synthesis or formulation) PROC4: Use in batch and other process (synthesis) where opportunity for exposure arises PROC8a: Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at non-dedicated facilities PROC8b: Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at dedicated facilities PROC10: Roller application or brushing PROC11: Non industrial spraying PROC13: Treatment of articles by dipping and pouring ERC8a: Wide dispersive indoor use of processing aids in open systems ERC8d: Wide dispersive outdoor use of processing aids in open systems

2.1 Contributing scenario controlling environmental exposure for: ERC8a, ERC8d In the chemical safety assessment performed according to Article 14(3) in connection with Annex I section 3 (Environmental Hazard Assessment) and section 4 (PBT/vPvB Assessment) no hazard was Identified., Therefore according on REACH Annex I (5.0) an exposure estimation and risk characterisation is not necessary 2.2 Contributing scenario controlling worker exposure for: PROC1, PROC2, PROC3, PROC4,

PROC8a, PROC8b , PROC10 , PROC11 , PROC13


liquid

> 100 hPa


Assumes use at not more than 20°C above ambient temp erature, unless stated differently., Assumes a good basic standard of occupational hygiene is implemented. Limit the substance content in the mixture to 25 %.(PROC2, PROC4, PROC8a, PROC8b) Limit the substance content in the mixture to 5 %.(PROC10, PROC11, PROC13)

21/35 EN




Frequency and duration of use

Other operational conditions affecting workers exposure PA100049_001




provide a good standard of general ventilation (not less than 3 to 5 air changes per hour).(PROC8b)

provide a good standard of general ventilation (not less than 3 to 5 air changes per hour).(PROC2)

Avoid carrying out operation for more than 4 hours.(PROC2, PROC3)

Provide a good standard of general or controlled ventilation (5 to 15 air changes per hour).(PROC4)

Ensure operation is undertaken outdoors. Avoid carrying out operation for more than 1 hour.(PROC8a, PROC8b)

provide a good standard of general ventilation (not less than 3 to 5 air changes per hour).(PROC13)


Ensure operation is undertaken outdoors.(PROC11)


Ensure operation is undertaken outdoors. or provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). Avoid carrying out operation for more than 4 hours.(PROC10)


Ensure operation is undertaken outdoors. or

EN

Filling / preparation of equipment from drums or containers Dedicated facility Automated process with (semi) closed systems Use in contained systems Automated process with (semi) closed systems Use in contained systems Drum/batch transfers Semi-automated process (e.g.: Semi-automatic application of floor care and maintenance products) Filling / preparation of equipment from drums or containers Manual cleaning Dipping, immersion and pouring Cleaning with low- pressure washers Rolling, Brushing No spraying Cleaning with high pressure washers Spraying Outdoor. Cleaning with high pressure washers Spraying Indoor. Manual Surfaces cleaning Spraying Ad hoc manual application via trigger sprays, dipping, etc Ad hoc manual application via trigger

22/35

Version 1.0



PA100049_001



provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). Avoid carrying out operation for more than 4 hours.(PROC10) Provide extract ventilation to points where emissions occur.(PROC4) Drain down and flush system prior to equipment opening or maintenance. provide a good standard of general ventilation (not less than 3 to 5 air changes per hour).(PROC8a, PROC8b) provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). or Ensure operation is undertaken outdoors.(PROC2)

Provide basic employee training to prevent/minimize exposures(PROC8a, PROC8b)

Provide basic employee training to prevent/minimize exposures(PROC11)

Wear suitable gloves tested to EN374.(PROC8b)

Wear suitable gloves tested to EN374.(PROC2)

Wear suitable gloves tested to EN374.(PROC2, PROC3)



Wear a respirator conforming to EN140 with Type A filter or better.(PROC11)

EN

Version 1.0


Organisational measures to prevent /limit releases, dispersion and exposure

Conditions and measures related to personal protection, hygiene and health evaluation PA100049_001

sprays, dipping, etc

cleaning Equipment cleaning and maintenance Storage with occasional controlled exposure

Filling / preparation of equipment from drums or containers Cleaning with high pressure washers Spraying Outdoor. Filling / preparation of equipment from drums or containers Dedicated facility Automated process with (semi) closed systems Use in contained systems Automated process with (semi) closed systems Use in contained systems Drum/batch transfers Manual cleaning Dipping, immersion and pouring Cleaning with low- pressure washers Rolling, Brushing No spraying Cleaning with high pressure washers Spraying Outdoor.

23/35



Wear a respirator conforming to EN140 with Type A filter or better. Wear suitable gloves tested to EN374.(PROC11)



Wear suitable gloves tested to EN374.(PROC8a, PROC8b)

2.3 Contributing scenario controlling worker exposure for: PROC4 Product characteristics

Frequency and duration of use Other operational conditions affecting workers exposure



Workers


Exposure Scenario

Guidance is based on assumed operating conditions which may not be applicable to all sites; thus, scaling may be necessary to define appropriate site-specific risk management measures. Estimated exposures are not expected to exceed PNEC when the identified Risk Management Measures / Operational Conditions are adopted, as indicated in Section 2

PA100049_001 24/35 EN


Covers concentrations up to 5%

liquid

> 100 hPa

Version 1.0


Cleaning with high pressure washers Spraying Indoor. Manual Surfaces cleaning Spraying Ad hoc manual application via trigger sprays, dipping, etc Equipment cleaning and maintenance

Covers daily exposures up to 8 hours (unless stated differently). Assumes use at not more than 20°C above ambient temp erature, unless stated differently.

Application of cleaning products in closed systems Outdoor.

Ensure operation is undertaken outdoors.(PROC4)




Predicted exposures are not expected to exceed the DN(M)EL when the Risk Management Measures/Operational Conditions outlined in Section 2 are implemented. Where other Risk Management Measures/Operational Conditions are adopted, then users should ensure that risks are managed to at least equivalent levels.



PA100049_001 25/35 EN



Revision Date 14.06.2013 1. Short title of Exposure Scenario 5: Use in laboratories

SU 3: Industrial uses: Uses of substances as such or in preparations at industrial sites SU 10: Formulation [mixing] of preparations and/ or re-packaging (excluding alloys)

Roller application or brushing Use as laboratory reagent

Industrial use of processing aids in processes and products, not becoming articles

2.1 Contributing scenario controlling environmental exposure for: ERC4 In the chemical safety assessment performed according to Article 14(3) in connection with Annex I section 3 (Environmental Hazard Assessment) and section 4 (PBT/vPvB Assessment) no hazard was Identified., Therefore according on REACH Annex I (5.0) an exposure estimation and risk characterisation is not necessary 2.2 Contributing scenario controlling worker exposure for: PROC10, PROC15


Frequency and duration of use Other operational conditions affecting workers exposure



PA100049_001

Handle in a fume cupboard or under extract ventilation.(PROC15) Provide a good standard of general or controlled ventilation (5 to 15 air changes per hour). Avoid carrying out operation for more than 1 hour.(PROC10) Wear suitable gloves tested to EN374.(PROC10)

EN

Laboratory activities

cleaning Rolling, Brushing Vessel and container cleaning with local exhaust ventilation cleaning Rolling, Brushing Vessel and container

26/35



PROC10: PROC15: ERC4:

Covers daily exposures up to 8 hours (unless stated differently). Assumes use at not more than 20°C above ambient temp erature, unless stated differently., Assumes a good basic standard of occupational hygiene is implemented.

part of

Covers percentage substance in the product up to 100 % (unless stated differently). liquid

> 100 hPa





cleaning with local exhaust ventilation


Workers


Exposure Scenario


PA100049_001 27/35 EN



Revision Date 14.06.2013 1. Short title of Exposure Scenario 6: Use in laboratories

SU 22: Professional uses: Public domain (administration, education, entertainment, services, craftsmen) PROC10: PROC15: ERC8a: Wide dispersive indoor use of processing aids in open systems

2.1 Contributing scenario controlling environmental exposure for: ERC8a In the chemical safety assessment performed according to Article 14(3) in connection with Annex I section 3 (Environmental Hazard Assessment) and section 4 (PBT/vPvB Assessment) no hazard was Identified., Therefore according on REACH Annex I (5.0) an exposure estimation and risk characterisation is not necessary 2.2 Contributing scenario controlling worker exposure for: PROC10, PROC15


liquid

> 100 hPa


Assumes use at not more than 20°C above ambient temp erature, unless stated differently.

Handle in a fume cupboard or under extract ventilation.(PROC15)

Provide a good standard of general or controlled ventilation (5 to 15 air changes per hour). Avoid carrying out operation for more than 1 hour.(PROC10)

Wear chemically resistant gloves (tested to EN374) in combination with ‘basic’ employee training.(PROC10)

EN





Frequency and duration of use Other operational conditions affecting workers exposure Technical conditions and measures to control dispersion from source towards the worker Conditions and measures related to personal protection, hygiene and health evaluation PA100049_001

Laboratory activities

cleaning Rolling, Brushing Vessel and container cleaning with local exhaust ventilation cleaning Rolling, Brushing Vessel and container cleaning with local exhaust ventilation

28/35

Roller application or brushing Use as laboratory reagent



Revision Date 14.06.2013 3. Exposure estimation and reference to its source

Workers


Exposure Scenario




PA100049_001 29/35 EN



Revision Date 14.06.2013 1. Short title of Exposure Scenario 7: Use as water treatment chemicals

SU 3: Industrial uses: Uses of substances as such or in preparations at industrial sites SU8: Manufacture of bulk, large scale chemicals (including petroleum products) SU9: Manufacture of fine chemicals PROC1: Use in closed process, no likelihood of exposure PROC2: Use in closed, continuous process with occasional controlled exposure PROC3: Use in closed batch process (synthesis or formulation) PROC4: Use in batch and other process (synthesis) where opportunity for exposure arises PROC8a: Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at non-dedicated facilities PROC8b: Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at dedicated facilities PROC15: Use as laboratory reagent ERC1:


PROC8a, PROC8b , PROC15


liquid

> 100 hPa


Assumes use at not more than 20°C above ambient temp erature, unless stated differently. Limit the substance content in the mixture to 25 %.(PROC4)

Bulk transfers Ensure material transfers are under containment or

30/35 EN

Manufacture of substances






Other operational conditions affecting workers exposure Technical conditions and measures to control dispersion PA100049_001



extract ventilation. Avoid carrying out operation for more than 4 hours.(PROC8a, PROC8b) provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). Provide extract ventilation to points where emissions occur.(PROC8a) Ensure operation is undertaken outdoors. or provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). Avoid carrying out operation for more than 4 hours.(PROC4) Ensure operation is undertaken outdoors. or provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). Drain down system prior to equipment break-in or maintenance.(PROC8a) Use drum pumps. Avoid spillage when withdrawing pump. Avoid carrying out operation for more than 4 hours.(PROC8b) Ensure operation is undertaken outdoors. or provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). Avoid carrying out operation for more than 1 hour.(PROC3) Store substance within a closed system.(PROC1, PROC2)

Wear suitable gloves tested to EN374.(PROC8a)



Wear suitable gloves tested to EN374.(PROC8b)

EN

Pouring from small containers Treatment by dipping and pouring General exposures (open systems) Equipment cleaning and maintenance Drum/batch transfers Dedicated facility

General exposures (closed systems) Batch process Storage

Pouring from small containers General exposures (open systems) Equipment cleaning and maintenance Drum/batch transfers Dedicated facility


Workers PA100049_001 31/35

Version 1.0


from source towards the worker






Exposure Scenario




PA100049_001 32/35 EN



Revision Date 14.06.2013 1. Short title of Exposure Scenario 8: Use in Oil and Gas field drilling and production operations

SU 3: Industrial uses: Uses of substances as such or in preparations at industrial sites SU 10: Formulation [mixing] of preparations and/ or re-packaging (excluding alloys) PROC1: Use in closed process, no likelihood of exposure PROC2: Use in closed, continuous process with occasional controlled exposure PROC3: Use in closed batch process (synthesis or formulation) PROC4: Use in batch and other process (synthesis) where opportunity for exposure arises PROC8a: Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at non-dedicated facilities PROC8b: Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at dedicated facilities PROC15: Use as laboratory reagent ERC1:


PROC8a, PROC8b , PROC15


liquid

> 100 hPa


Assumes use at not more than 20°C above ambient temp erature, unless stated differently. Limit the substance content in the mixture to 25 %.(PROC4)

Bulk transfers Ensure material transfers are under containment or

33/35 EN

Manufacture of substances






Other operational conditions affecting workers exposure Technical conditions and measures to control dispersion PA100049_001



extract ventilation.(PROC8a, PROC8b) Use drum pumps. provide a good standard of general ventilation (not less than 3 to 5 air changes per hour).(PROC8a, PROC8b) Ensure operation is undertaken outdoors. or provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). Avoid carrying out operation for more than 4 hours.(PROC4) Ensure material transfers are under containment or extract ventilation.(PROC4) Ensure material transfers are under containment or extract ventilation.(PROC3) Use a sampling system designed to control exposure. Ensure operation is undertaken outdoors. or provide a good standard of general ventilation (not less than 3 to 5 air changes per hour).(PROC8b)

Handle substance within a closed system.(PROC2)

Ensure operation is undertaken outdoors. or provide a good standard of general ventilation (not less than 3 to 5 air changes per hour).(PROC8a) Ensure operation is undertaken outdoors. or provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). Avoid carrying out operation for more than 4 hours.(PROC4) Ensure operation is undertaken outdoors. or provide a good standard of general ventilation (not less than 3 to 5 air changes per hour). Avoid carrying out operation for more than 1 hour.(PROC8a) Handle substance within a closed system. Provide extraction ventilation at points where emissions occur.(PROC4)

Wear suitable gloves tested to EN374.(PROC8a, PROC8b)


EN

Filling / preparation of equipment from drums or containers Drill floor operations

Operation of solids filtering equipment Treatment and disposal of filtered solids

Process sampling

General exposures (closed systems) Pouring from small containers General exposures (open systems) Equipment cleaning and maintenance

Batch process Product sampling

Filling / preparation of equipment from drums or containers Pouring from small

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from source towards the worker Conditions and measures related to personal protection, hygiene and health evaluation

PA100049_001


acetic acid...% Version 1.0


containers General exposures (open systems) Equipment cleaning and maintenance


Workers


Exposure Scenario




PA100049_001 35/35 EN

Print Date 14.06.2013 Wear suitable gloves tested to EN374.(PROC4) Wear suitable gloves tested to EN374.(PROC8a)

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