Nicotine

Adam Hoza

Alexandra Rychová

What is nicotine?

pyridin-N-metylpyrrolidin

liquid alkaloid included in tobacco

is bound to acid apple or lemonish and his quantity in plant notching as far as 8%

is washable and dozen

fresh is odourless, otherwise dirtily smells and tastes pungently

N

N

CH3

Effects of nicotine on man

has ability to liberate dopamin thereby evoke pleasant feelingshelps smokers to refresh memory namely thanks to activation of acetylcholine stepsreleases epinephrine from suprarenal gland works vegetative nerve knot, NS plate, CNS (at overdosing shake)turns sensation taste foods and sensation enjoyment from foods

Why is nicotine so dangerous?

mitotic poisoning of organoleptic nucleus of a cell (fatal dose is 50mg)

at high taxs: overall attenuation of CNS> apneusis > death

manifestations of poisoning: nauzea, vomit, diarrhoea, salivation, cold sweat, fuzziness

How does nicotine get to human body?

row plants include nicotine, they come largely from America mostly nicotine is included in tobacco (0.6-8%)to the bodies it gets by smoking, snuff or chewing leafs nicotinic receptors respond very fastIncidence on body is up to several minutes, however way nicotine goes from lungs to the brain nicotine mere 7,5 seconds

Something about the story of tobacco

During Antiquity and Middle Ages Europe didn‘t know about tobaccoFirst tobacco was taken to Europe by Kolumbus in the year 1492Seeds of tobacco got here some about 20 years later Biggest worth has Frenchman Jean Nicotothat who took it to French court in 1560, namely in develoment of practice of snuffing powder

Diseases incurred by smoking

Cardio-vascular disorder (25%)

Tuberculous disorder (30%)

Chronic pulmonary disorder (75%)

červeně je zobrazena celková úmrtnost v ČR, zeleně choroby související s kouřením; oboje vztaženo na 100.000 obyvatel

Vocabulary:

Thank you for your attention