Nervous System. Divisions Central nervous system (CNS). Brain and spinal cord. Both contain...

20
Nervous System

Transcript of Nervous System. Divisions Central nervous system (CNS). Brain and spinal cord. Both contain...

Page 1: Nervous System. Divisions Central nervous system (CNS). Brain and spinal cord. Both contain fluid-filled spaces which contain cerebrospinal fluid (CSF).

Nervous System

Page 2: Nervous System. Divisions Central nervous system (CNS). Brain and spinal cord. Both contain fluid-filled spaces which contain cerebrospinal fluid (CSF).

Divisions

•Central nervous system (CNS).▫Brain and spinal cord.

Both contain fluid-filled spaces which contain cerebrospinal fluid (CSF). The central canal of the spinal cord is

continuous with the ventricles of the brain.▫White matter is composed of bundles of

myelinated axons▫Gray matter consists of unmyelinated axons,

nuclei, and dendrites.•Peripheral nervous system.

▫Everything outside the CNS.

Copyright © 2002 Pearson Education, Inc., publishing as Benjamin Cummings

Page 3: Nervous System. Divisions Central nervous system (CNS). Brain and spinal cord. Both contain fluid-filled spaces which contain cerebrospinal fluid (CSF).

PNS

Copyright © 2002 Pearson Education, Inc., publishing as Benjamin Cummings

Fig. 48.17

Page 4: Nervous System. Divisions Central nervous system (CNS). Brain and spinal cord. Both contain fluid-filled spaces which contain cerebrospinal fluid (CSF).

Neuron Anatomy

Page 5: Nervous System. Divisions Central nervous system (CNS). Brain and spinal cord. Both contain fluid-filled spaces which contain cerebrospinal fluid (CSF).

Membrane Potential

•Measuring Membrane Potentials.▫-70 mV is

resting

Copyright © 2002 Pearson Education, Inc., publishing as Benjamin Cummings

Page 6: Nervous System. Divisions Central nervous system (CNS). Brain and spinal cord. Both contain fluid-filled spaces which contain cerebrospinal fluid (CSF).

Normal Levels

Copyright © 2002 Pearson Education, Inc., publishing as Benjamin Cummings

Fig. 48.7

Page 7: Nervous System. Divisions Central nervous system (CNS). Brain and spinal cord. Both contain fluid-filled spaces which contain cerebrospinal fluid (CSF).

Hyperpolarization.

•Gated K+ channels open K+ diffuses out of the cell the membrane potential becomes more negative.

Copyright © 2002 Pearson Education, Inc., publishing as Benjamin Cummings

Fig. 48.8a

Page 8: Nervous System. Divisions Central nervous system (CNS). Brain and spinal cord. Both contain fluid-filled spaces which contain cerebrospinal fluid (CSF).

Depolarization

•Gated Na+ channels open Na+ diffuses into the cell the membrane potential becomes less negative.

Copyright © 2002 Pearson Education, Inc., publishing as Benjamin Cummings

Fig. 48.8b

Page 9: Nervous System. Divisions Central nervous system (CNS). Brain and spinal cord. Both contain fluid-filled spaces which contain cerebrospinal fluid (CSF).

Action Potential

•The Action Potential: All or Nothing Depolarization.▫If graded potentials sum

to -55mV a threshold potential is achieved. This triggers an action

potential. Axons only.

Copyright © 2002 Pearson Education, Inc., publishing as Benjamin Cummings

Fig. 48.8c

Page 10: Nervous System. Divisions Central nervous system (CNS). Brain and spinal cord. Both contain fluid-filled spaces which contain cerebrospinal fluid (CSF).

•Step 1: Resting State.

Copyright © 2002 Pearson Education, Inc., publishing as Benjamin Cummings

Fig. 48.9

Page 11: Nervous System. Divisions Central nervous system (CNS). Brain and spinal cord. Both contain fluid-filled spaces which contain cerebrospinal fluid (CSF).

•Step 2: Threshold.

Copyright © 2002 Pearson Education, Inc., publishing as Benjamin Cummings

Fig. 48.9

Page 12: Nervous System. Divisions Central nervous system (CNS). Brain and spinal cord. Both contain fluid-filled spaces which contain cerebrospinal fluid (CSF).

•Step 3: Depolarization phase of the action potential.

Copyright © 2002 Pearson Education, Inc., publishing as Benjamin Cummings

Fig. 48.9

Page 13: Nervous System. Divisions Central nervous system (CNS). Brain and spinal cord. Both contain fluid-filled spaces which contain cerebrospinal fluid (CSF).

•Step 4: Repolarizing phase of the action potential.

Copyright © 2002 Pearson Education, Inc., publishing as Benjamin Cummings

Fig. 48.9

Page 14: Nervous System. Divisions Central nervous system (CNS). Brain and spinal cord. Both contain fluid-filled spaces which contain cerebrospinal fluid (CSF).

•Step 5: Undershoot.

Copyright © 2002 Pearson Education, Inc., publishing as Benjamin Cummings

Fig. 48.9

Page 15: Nervous System. Divisions Central nervous system (CNS). Brain and spinal cord. Both contain fluid-filled spaces which contain cerebrospinal fluid (CSF).

Copyright © 2002 Pearson Education, Inc., publishing as Benjamin Cummings

Fig. 48.10

Moving Potential

Page 16: Nervous System. Divisions Central nervous system (CNS). Brain and spinal cord. Both contain fluid-filled spaces which contain cerebrospinal fluid (CSF).

Saltatory conduction

•In myelinated neurons only unmyelinated regions of the axon depolarize.

Thus, the impulse moves faster than in unmyelinated neurons.

Copyright © 2002 Pearson Education, Inc., publishing as Benjamin Cummings

Fig. 48.11

Page 17: Nervous System. Divisions Central nervous system (CNS). Brain and spinal cord. Both contain fluid-filled spaces which contain cerebrospinal fluid (CSF).

Synapses

•Electrical Synapses.▫Action potentials travels directly from the

presynaptic to the postsynaptic cells via gap junctions.

Copyright © 2002 Pearson Education, Inc., publishing as Benjamin Cummings

Page 18: Nervous System. Divisions Central nervous system (CNS). Brain and spinal cord. Both contain fluid-filled spaces which contain cerebrospinal fluid (CSF).

Chemical Synapses

•More common than electrical synapses.•Postsynaptic chemically-gated channels

exist for ions such as Na+, K+, and Cl-. Depending on which gates open the

postsynaptic neuron can depolarize or hyperpolarize.

Copyright © 2002 Pearson Education, Inc., publishing as Benjamin Cummings

Page 19: Nervous System. Divisions Central nervous system (CNS). Brain and spinal cord. Both contain fluid-filled spaces which contain cerebrospinal fluid (CSF).

Copyright © 2002 Pearson Education, Inc., publishing as Benjamin Cummings

Fig. 48.12

Page 20: Nervous System. Divisions Central nervous system (CNS). Brain and spinal cord. Both contain fluid-filled spaces which contain cerebrospinal fluid (CSF).

Routes of Nerve Transmission