The Nervous System: Neurotransmitters By Josephina, Ben, Andrew, and Jacob
Nervous system 3; Synapses and Neurotransmitters
20
Nervous system 3 Neuron synapses Neurotransmitters Effects of drugs on synapses
-
Upload
james-h-workman -
Category
Education
-
view
457 -
download
1
description
Lecture notes and diagrams for Anatomy and Physiology students describing / showing the connections between nerve cells (synapses) and how neurotransmitters work. Video of animation that shows how drugs affect neurotransmitters is included, although it will not show in slideshare.
Transcript of Nervous system 3; Synapses and Neurotransmitters
Nervous system 3
Neuron synapsesNeurotransmitters
Effects of drugs on synapses
One direction
No that’s not what I meant.
SynapseA structure that permits a neuron (nerve cell) to pass an electrical or chemical signal to another cell.
Excitatory post synaptic potential
Inhibitory post synaptic potential
Types of synapses
Electrical v. Chemical synapse
Types of synapsesSynapse with another neuron
Junction between two nerve cells
NeuroeffectorNeuromuscular: synapse of motor neuron and
muscleNeuroglandular: synapse of neuron and endocrine
or exocrine gland.
NeurotransmittersExcitatory – can cause next cell to initiate a new impulse– ACh (acetylcholine) – neuromuscular junction– NE (norepinephrine)– DA (dopamine)
NeurotransmittersInhibitory– can cause hyperpolarization of next cell, reduce chance of a new impulse– Serotonin– GABA (gamma aminobutyric acid)– Glycine
Convergence and Divergence
Synapse functionEssential for homeostasisA problem with communication between nerves at synapses is often the basis for disease
Examples: Parkinsons, Azheimers, depression, anxiety, schizophrenia
Drug effects Can increase permeability of nerve cell membrane to Na+ makes impulses more likelyCan decrease permeability of nerve cell membrane to Na+ makes impulses less likelyCan block / compete for receptor site binding
Aspirin, Morphine, CurareCan inhibit secretory vesicle formation / release
Botulism / Tetanus
