A Brain-Like Computer for Cognitive Applications: The Ersatz Brain Project
My experience in brain cognitive research for summer minority high school students
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Transcript of My experience in brain cognitive research for summer minority high school students
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My experience in brain cognitive research for summer minority high school students
Ron Hu, M.D.Johnson Foundation Summer Research Program ‘01
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Summer 2001
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Summer Program
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Summer Program
Picture
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The Knot Tying Experiment
Tests how brain engages in motor learning
Subjects learn two sailor’s knots
Brain oxygenation and performance data gathered
BowlineClove hitch
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Hypotheses
1.The prefrontal cortex is involved in learning motor function2.An imagery period will enhance the performance of subjects3.Repetition learning in the subjects will subsequently decrease brain activation.
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Methods
18 subjects randomly split into two groups
Exp group asked to imagine tying knot before trial
Control group had rest period before trial
Each subject tested 4 times with at least one day between each test
Performance was compared
Baseline
Video Gap Trial Period
Baseline
Video Imagery
Trial Period
Control
Experimental
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Oxygenation Prefrontal cortex
-0.06
-0.04
-0.02
0
0.02
0.04
0.06
0.08
0.1
0.12
0.14
Video Imagery Trial
Change in oxygenation from baseline
Pre-frontal cortex activation was associated with imagining and actual knot-tying
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Best Performer
420 440 460 480 500 520 540 560 580
2
2.5
3
3.5
4
4.5
5
5.5
6
6.5
Sample Point
D4
Baseline Video Imagery Trial
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Worst performer
900 920 940 960 980 1000 1020
0.6
0.7
0.8
0.9
1
1.1
1.2
1.3
1.4
Sample Point
D12
Baseline Video Imagery Trial
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Performance
Stage 2: Non-Imagery Clove H.
0
1
2
3
4
5
6
1 2 3 4
Test
Stage 2: Imagery Clove H.
012
3456
78
1 2 3 4
Test
Imagery period did not improve performance in our subjects
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Repetition learning
Day1 vs Day4 Clove H.
0
0.05
0.1
0.15
0.2
0.25
0.3
0.35
0.4
Imagery Trial
Day 1
Day 4
Learning did occur as subjects gained experience in tying the knots, and the overall activation decreased
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Since Summer Program
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The future
Thank you!Prefrontal Cortex