Mutations

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13.3 Mutations

Transcript of Mutations

Page 1: Mutations

13.3 Mutations

Page 2: Mutations

Gene Mutations

• Mutation – change in the genetic material of a cell

• Point mutations–Changes in one or a few nucleotides– Insertions, deletions, substitutions

• Frameshift mutations–Reading frame of the genetic code is shifted– Insertions and deletions are examples

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Chromosomal Mutations

• Change in the number or structure of chromosomes

• Can change location of genes on chromosomes, or the number of copies of some genes

• Four types are: deletion, duplication, inversion, and translocation (see page 318)

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Effects of Mutations• Chemical or physical agents in the

environment that can alter genetic material

• Can help or harm organisms, although most have little or no effect

• Chemical mutagens can include: pesticides, tobacco smoke, and pollutants

• Physical mutagens can include: x-rays and ultraviolet light

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Example

• Sickle cell anemia (see page 318)–Caused by point mutation–Causes red blood cells to change shape–Sickle-shaped cells interfere with blood

flow and can cause severe problems in bloodstream